WO2014073568A1 - Lentille de contact colorée à couche mince de côté face intérieure et son procédé de fabrication - Google Patents

Lentille de contact colorée à couche mince de côté face intérieure et son procédé de fabrication Download PDF

Info

Publication number
WO2014073568A1
WO2014073568A1 PCT/JP2013/080014 JP2013080014W WO2014073568A1 WO 2014073568 A1 WO2014073568 A1 WO 2014073568A1 JP 2013080014 W JP2013080014 W JP 2013080014W WO 2014073568 A1 WO2014073568 A1 WO 2014073568A1
Authority
WO
WIPO (PCT)
Prior art keywords
contact lens
polymer
lens
mold
colored
Prior art date
Application number
PCT/JP2013/080014
Other languages
English (en)
Japanese (ja)
Inventor
岡田　務
麻衣 鈴木
Original Assignee
株式会社メニコンネクト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式会社メニコンネクト filed Critical 株式会社メニコンネクト
Priority to JP2014545732A priority Critical patent/JPWO2014073568A1/ja
Publication of WO2014073568A1 publication Critical patent/WO2014073568A1/fr

Links

Images

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04—Contact lenses for the eyes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D11/00—Producing optical elements, e.g. lenses or prisms
    • B29D11/00009—Production of simple or compound lenses
    • B29D11/00038—Production of contact lenses
    • B29D11/00048—Production of contact lenses composed of parts with dissimilar composition
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D11/00—Producing optical elements, e.g. lenses or prisms
    • B29D11/0073—Optical laminates
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/10—Filters, e.g. for facilitating adaptation of the eyes to the dark; Sunglasses

Definitions

  • the present invention relates to a contact lens having a two-layer structure in the thickness direction and a colored portion between the two layers, and a method for producing a laminated colored contact lens by sequentially polymerizing each layer in a mold. Is.
  • a method of polymerizing a contact lens (hereinafter sometimes simply referred to as “lens”) in a mold generally includes a female mold that forms the front side of the lens and a rear surface side.
  • a lens is obtained by filling a polymerizable monomer between the male mold and forming a lens and irradiating with heat or ultraviolet rays. Since the process is simple and short in this way, it has been widely adopted as a manufacturing method for disposable lenses, which has become the mainstream in recent years.
  • the lens can be provided at low cost by the mold manufacturing method.
  • it has been required to increase the added value of the lens by adding new functions by utilizing the characteristics of the mold manufacturing method.
  • An example of increasing the added value of a lens is a colored lens that objectively changes the color or texture of the pupil.
  • These lenses are also called irised lenses, but the manufacturing method for these lenses is to coat the colored monomer component on the part that forms the iris part of the lens molding die surface, form a film, and then fill and polymerize the lens monomer component.
  • a method in which a colored lens is formed when removed from the mold (Patent Document 1), a colored liquid film is deposited in the mold, and the liquid lens-forming mixture is applied to the mold while maintaining the position of the colored film.
  • Patent Document 2 There is a method (Patent Document 2) of filling and forming a molded contact lens in which the film surface and the lens body are integrated.
  • the colored portion does not appear to protrude on the lens surface, and the wearer's eyelid or the like does not cause a sense of incongruity directly.
  • a colored portion may appear on the lens surface.
  • the colored portion may peel off, resulting in irritation to the wearer or the colored portion.
  • the difference in hardness between the surrounding area and the surrounding area is a risk that dirt may adhere to the colored portions appearing on the lens surface.
  • a so-called sandwich sandwiching the colored portion inside the lens that is, a sandwich type lens
  • a sandwich type lens For example, after a colored part is provided between the hydrogel layers of the lens, the hydrogel is joined by polymerization (Patent Document 3), and an iris shielding means is provided between the first lens part and the second lens part.
  • a method of disposing and joining the first lens portion and the second lens portion (Patent Document 4), a transfer material provided with a transfer layer for forming a colored portion is placed in a female mold, A method of injecting a contact lens material between male molds forming a polymer (Patent Document 5), forming a first lens material in a concave mold, that is, a female mold, and forming a functional material serving as a colorant thereon After printing, the lens material is filled, and a convex surface that is paired with the female mold, that is, a method of polymerizing by fitting the male mold (Patent Document 6) or a colored layer having a predetermined thickness by a mold manufacturing method. There are at least two lenses comprising a transparent layer having a predetermined thickness (Patent Document 7) or the like is arranged in. A colored lens in which a colored portion is coated with a coat layer has been proposed (Patent Document 8).
  • the method of Reference 3 does not use a mold, and the method of Reference 4 is supposed to perform processing by a standard method after a manufacturing method using a mold.
  • the manufacturing cost is high and complicated.
  • the method of Document 5 does not make the lens into a two-layer structure, but uses a transfer layer for coloring, etc., so that the handling of the transfer layer causes a problem in coloring quality and the manufacturing cost is high. There is a risk.
  • a functional material such as a light shielding material is applied to a concave mold and transferred to a lens, so that it has a two-layer structure and a colored portion between the two layers.
  • the method of Document 7 can provide a lens having a three-dimensional appearance by using alternately arranged transparent layers and colored layers, and although the thickness of each layer is also described, There is no mention of any issues.
  • Reference 8 describes a lens comprising a lens-forming polymer, a front lens surface, a rear lens surface, a colorant applied to the exterior of the front or rear lens surface, and a colorant coated with a coat layer.
  • a process of forming a coat layer is necessary, and the lens of Document 8 may cause eye irritation due to dropping off of the colorant containing the coat layer.
  • the colored contact lens has a two-layer structure and the colored portion is a sandwich type.
  • a polymer provided with the inner surface of the contact lens that is, the surface in contact with the eyeball when the contact lens is worn on the eyeball, hereinafter simply referred to as “inner surface”.
  • inner surface a polymer provided with the inner surface of the contact lens
  • outer surface a polymer layer provided with an outer surface side surface of the contact lens (that is, a surface contacting the outside when the contact lens is worn on the eyeball, hereinafter simply referred to as “outer surface”).
  • the sandwich type contact lens there are a lens having a thinner polymer layer having an outer surface and a lens having a thicker one than a polymer layer having an inner surface.
  • colored lenses in which the thickness of the polymer layer having the inner surface of the contact lens is thinner than the thickness of the polymer layer having the outer surface of the contact lens are described in Documents 4 and 7 among the documents.
  • these documents do not recognize the problems in the present invention described below, and naturally do not describe the problems to be solved. Therefore, there is no means for solving the problems and problems of the present invention. It can be said that it was still a solution.
  • the object of the present invention is to compare the thickness of the polymer layer having the inner surface with the thickness of the polymer layer having the outer surface in the two-layer colored contact lens by the mold manufacturing method, and the former is not thinner than the latter.
  • the problem is that the colored contact lens is easily displaced from the eyes, the fitting is changed, and the dryness is increased.
  • the inventors of the present invention also found that the stress remaining on the colored contact lens by the mold manufacturing method that was relaxed in the hydrated, equilibrium swollen colored contact lens is not relaxed in the colored contact lens in the dry state.
  • the lens shape is changed so as to cause a change. Furthermore, when the residual stress is strong, the inventors have found that the shape of the hydrated and swollen colored contact lens is remarkably changed, leading to a decrease in the yield rate and cost increase.
  • the possibility of the shape change of the colored contact lens is possessed by the contact lens even if the contact lens is not in a dry state. For example, the contact lens may become apparent when the contact lens that is not in a dry state is cut. In other words, when the contact lens is cut, the contact lens that does not have the possibility of shape change retains the original uneven shape of the contact lens, but the contact lens that may change shape has the original uneven state. The shape may be more distorted. Therefore, the present invention has solved the above-mentioned problems by defining the thickness of a polymer layer having an inner surface to a predetermined thickness, and has completed the invention.
  • a first problem of the present invention is that a sandwich-type colored contact lens having a two-layer structure has a stable shape even when worn for a long time by defining the thickness of a polymer layer having an inner surface to be a predetermined thickness. It is to provide a colored contact lens that can be maintained. More specifically, the shape of the colored contact lens changes due to the dry state of the colored contact lens that is inevitably generated during wearing, which impairs visual stability and makes the colored contact lens easily displaced. Thus, the problem that the feeling of wearing becomes worse, the fitting and appearance change, and the feeling of dryness becomes stronger is solved by maintaining the shape retaining property of the colored contact lens. And the 2nd subject of this invention is to prevent the fall of the yield rate of the colored contact lens which has a 2 layer structure by a mold manufacturing method, and to improve productivity.
  • a first aspect of the present invention is a colored contact lens having a center thickness of 80 ⁇ m or more and 200 ⁇ m or less, the first polymer layer having an inner surface of the contact lens having a center thickness of 5 ⁇ m or more and 40 ⁇ m or less, and an outer surface of the contact lens
  • a colored contact lens comprising: a second polymer layer comprising: a light shielding material pattern portion between the two polymer layers.
  • a second aspect of the present invention is a colored contact lens having a center thickness of 50 ⁇ m or more and less than 80 ⁇ m, wherein the lower limit of the center thickness is 5 ⁇ m and the upper limit is 35% with respect to the center thickness of the contact lens.
  • the colored contact comprising: a first polymer layer having an inner surface; a second polymer layer having an outer surface of a contact lens; and a light shielding pattern portion between the two polymer layers. It is a lens.
  • a contact lens is formed in a space formed by matching a male mold having a convex molding surface and a female mold having a concave molding surface.
  • 1 lens forming material is filled and polymerized to form a first polymer, the male mold and the female mold are opened to fix the first polymer to the male mold, and the first mold fixed to the male mold
  • a light shielding material is applied to the exposed surface of the polymer, and a second die of the contact lens is formed in a space formed by matching the female die paired with the male die to which the first polymer is fixed.
  • 1st or 2nd aspect which fills the lens forming material of this, polymerizes, forms a 2nd polymer, and impregnates the physiological solution in the 2 layer polymer obtained by opening a male type
  • a contact lens in a space formed by matching a male mold having a convex molding surface and a female mold having a concave molding surface.
  • the lens forming material 2 is filled and polymerized to form a second polymer, the male mold and the female mold are opened, the second polymer is fixed to the female mold, and the second mold is fixed to the female mold.
  • a light shielding material is applied to the exposed surface of the polymer, and a first die of the contact lens is formed in a space formed by matching the male die paired with the female die to which the second polymer is fixed.
  • 1st or 2nd aspect which fills the lens formation material of this, polymerizes, forms a 1st polymer, and impregnates the physiological solution in the 2 layer polymer obtained by opening a male type
  • mold This is a method for producing a colored contact lens.
  • the inner surface of the contact lens refers to the surface that contacts the eyeball when the contact lens is worn
  • the outer surface of the contact lens that is, the FC-side outer surface is the opposite side of the BC-side inner surface.
  • a polymer constituting the inner surface layer is referred to as a “first polymer”
  • a polymer constituting the outer surface layer is referred to as a “second polymer”.
  • the colored contact lens of the present invention has a first polymer layer on the inner surface side and a second polymer layer on the outer surface side, and a pattern of light shielding material is provided between these two polymer layers. Has a part.
  • the first and second polymers constituting the colored contact lens of the present invention are generally provided as a soft lens after being impregnated with a physiological solution such as physiological saline and brought into an equilibrium swelling state.
  • a physiological solution such as physiological saline and brought into an equilibrium swelling state.
  • the term “polymer layer” refers to a layer-shaped polymer that has been hydrated and brought into an equilibrium swollen state as a result of impregnating a polymer constituting a colored contact lens with a physiological solution.
  • the “center thickness of the contact lens” means the thickness of the center portion of the contact lens when the polymer is impregnated with a physiological solution and hydrated to be in an equilibrium swollen state.
  • the center thickness of the colored contact lens is adjusted by the refractive index of the contact lens material, the required lens power, and the like, and is generally 50 ⁇ m or more and 200 ⁇ m or less. Therefore, the center thickness of the colored contact lens in the present invention is also preferably 50 ⁇ m or more and 200 ⁇ m or less, more preferably 80 ⁇ m or more and 200 ⁇ m or less, further preferably 80 ⁇ m or more and 140 ⁇ m or less, and most preferably 80 ⁇ m or more and 120 ⁇ m or less.
  • the lower limit of the center thickness of the first polymer layer provided with the inner surface of the colored contact lens is preferably 5 ⁇ m, more preferably 10 ⁇ m.
  • the thickness of the first polymer layer that is in contact with the male mold at the time of manufacturing the colored contact lens is less than 5 ⁇ m, the thinner the first polymer, the more stable quality is maintained in the formation of the first polymer. Difficult to do.
  • the center thickness of the first polymer layer is too thin, the distance between the cornea and the colored material is too small, which may cause an adverse effect on the cornea.
  • the upper limit of the center thickness of the first polymer layer having the inner surface is classified according to the center thickness of the colored contact lens.
  • the upper limit is preferably 40 ⁇ m, more preferably 35 ⁇ m, still more preferably 30 ⁇ m. This is because if the center thickness of the first polymer layer having the inner surface of the colored contact lens exceeds 40 ⁇ m, the problem of the present invention cannot be solved.
  • the upper limit is 35% as a ratio of the center thickness of the first polymer layer including the inner surface of the colored contact lens to the center thickness of the colored contact lens. Preferably, it is 32.5%, more preferably 30%.
  • the preferred range of the center thickness of the first polymer layer provided with the inner surface of the colored contact lens is preferably 5 ⁇ m or more and 40 ⁇ m or less.
  • the center thickness of the colored contact lens is 50 ⁇ m or more and less than 80 ⁇ m
  • the lower limit of the center thickness range of the first polymer layer provided with the inner surface of the colored contact lens is preferably 5 ⁇ m
  • the upper limit of the range is that of the lens.
  • the ratio of the colored contact lens to the center thickness is 35%.
  • a light shield is a substance that functions to color a contact lens by blocking a part of light that reaches the eyes from the outside. After the light shielding material is applied to the exposed surface of the first polymer by printing or the like, the second polymer is formed on the exposed surface of the first polymer, or the light shielding material is the second polymer.
  • the light shielding material can be sandwiched in the contact lens by forming the first polymer on the exposed surface of the second polymer after being applied to the exposed surface of the second polymer by printing or the like.
  • the pattern of the light shielding object is a pattern of the light shielding object.
  • the pattern is formed by printing, or the colored area surrounding the transparent central visual area is a continuous sea part.
  • a sea-island structure composed of the transparent portion and the discontinuous colored opaque portion of the island portion can be formed.
  • the thickness of the light shield is preferably 5 ⁇ m or more and 15 ⁇ m or less, and more preferably 8 ⁇ m or more and 12 ⁇ m or less. If the thickness of the light shielding material is less than 5 ⁇ m, the light shielding is insufficient, and if it exceeds 15 ⁇ m, the two polymer layers sandwiching the light shielding material may peel off, which may cause a problem in the shape retention of the contact lens. It is.
  • the ratio of the thickness of the light shielding layer to the center thickness of the first polymer layer provided with the inner surface of the colored contact lens is such that when the center thickness of the colored contact lens is 80 ⁇ m or more and 200 ⁇ m or less, the inner surface of the colored contact lens is Since the lower limit of the center thickness of the first polymer layer provided is 5 ⁇ m and the upper limit of the thickness of the light shielding layer is 15 ⁇ m, the maximum is 300%, and the center of the first polymer layer provided with the inner surface of the colored contact lens Since the upper limit of the thickness is 40 ⁇ m and the lower limit of the thickness of the light shielding layer is 5 ⁇ m, the minimum is 12.5%.
  • the center thickness of the colored contact lens is 50 ⁇ m or more and less than 80 ⁇ m
  • the lower limit of the center thickness of the first polymer layer including the inner surface of the colored contact lens is 5 ⁇ m
  • the upper limit of the thickness of the light shielding layer is 15 ⁇ m. Therefore, the upper limit of the center thickness of the first polymer layer provided with the inner surface of the colored contact lens is 28 ⁇ m, and the lower limit of the thickness of the light shielding layer is 5 ⁇ m. Therefore, the minimum is 17.9%. Become.
  • the “pair” in the third and fourth embodiments means that a lens forming material is added to a female mold, matched with the male mold, polymerized with the lens forming material, and opened to form both molds.
  • the lens forming material is a flowable polymerizable material that forms a lens after polymerization.
  • the lens forming material includes a first lens forming material and a second lens forming material.
  • the lens forming material that forms the first polymer layer having the inner surface is “first”.
  • the lens forming material that forms the second polymer layer having the outer surface of the contact lens is the “second lens forming material”.
  • the first lens forming material or the second lens forming material is polymerized between the matched male mold and female mold to form a first polymer or a second polymer, respectively.
  • the female mold and the male mold are opened in the next step.
  • the previously formed polymer is fixed to either the male mold or the female mold, and in the subsequent step, a light shielding material is applied to the exposed surface of the fixed polymer.
  • the first polymer is fixed to the male mold, and the light shield is applied to the exposed surface of the first polymer fixed to the male mold.
  • the mold that makes a pair with the male mold to which is fixed is a female mold.
  • the pair of female molds to be used subsequently may be new female molds that are not used, but those that have already been used in consideration of cost reduction may be reused.
  • the second polymer is fixed to the female mold, and the light shield is applied to the exposed surface of the second polymer fixed to the female mold.
  • a mold that makes a pair with a female mold to which an object is fixed becomes a male mold.
  • the pair of male molds to be used subsequently may be new male molds that are not used, but those that have already been used in consideration of cost reduction may be reused.
  • a first polymer is first formed, a light shielding pattern is formed, and then a second polymer is formed.
  • the first polymer is fixed to the male mold, and a light shielding material is formed on the convex portion of the first polymer, and the second polymer is joined along the concave surface.
  • the light shielding material can be applied twice or more, and thus different patterns can be applied to increase the added value.
  • the first polymer and the second polymer may be a transparent layer containing no dye or the like, or a colored transparent layer containing a dye or the like. This is because adding a dye or the like to the transparent layer may increase the added value in combination with the pattern of the light shielding object.
  • a 2nd polymer is formed first, the pattern of a light-shielding material is formed, and then a 1st polymer is formed.
  • the second polymer is fixed to the female mold, and a light shielding material is formed on the concave surface portion of the second polymer, and the second polymer is joined so that the convex surface of the first polymer follows.
  • the light shielding object can be applied two or more times, so that different patterns can be applied and the added value can be increased.
  • the first polymer and the second polymer may be a transparent layer containing no dye or the like, or a colored transparent layer containing a dye or the like.
  • the center thickness of the first polymer is the center of the lens on the male convex molding surface when the molds are matched. Defined by the distance between the point and the lens center point on the female concave mold surface.
  • the center thickness of the first polymer is determined by the center point of the male lens where the polymer is not fixed and the lens center of the exposed surface of the second polymer fixed to the female die. It will be determined by the distance of the points.
  • the colored contact lens of the present invention can be obtained by immersing the two-layered polymer obtained in the third and fourth aspects in a physiological solution such as physiological saline to bring it into an equilibrium swelling state.
  • the center thickness of the colored contact lens is finally determined by the center thickness of the two-layered polymer molded and bonded in the mold, swelling during hydration, shrinkage during polymerization, and the like.
  • the “center thickness” of the colored contact lens is a thickness after impregnating a physiological solution into a bilayer polymer to obtain an equilibrium swollen state.
  • the thickness obtained by dividing the thickness of each subsequent polymer layer by the linear expansion coefficient (LSR) of each polymer is the thickness of each polymer before the impregnation treatment, that is, at the time of production.
  • the colored contact lens manufactured by the above-described manufacturing method can add a new function as a colored contact lens having a two-layer structure in the colored thickness direction even if a lens material similar to the conventional lens material is used.
  • a lens material similar to the conventional lens material is used.
  • by superimposing the layer structure it is possible to provide a novel colored contact lens material as a whole by drawing out excellent points of each material and compensating for the defects.
  • the rate of non-defective products at the time of lens production will be improved to reduce costs.
  • the thickness of the first polymer layer provided with the inner surface of the colored contact lens a predetermined thickness, the deformation of the colored contact lens due to the unavoidable occurrence of water evaporation of the colored contact lens is suppressed and stable for a long period of time. Maintain shape.
  • the colored contact lens of the present invention has a two-layer structure, by using an appropriate material for each layer, a problem that cannot be solved by a single material is solved as a whole by combining a plurality of materials. Simple colored contact lenses.
  • FIG. 1 is a diagram for explaining a method for producing a colored contact lens having a two-layer structure.
  • FIG. 2 is a diagram for explaining another method for producing a colored contact lens having a two-layer structure.
  • FIG. 3 is a diagram showing a cross section in the diameter direction of a colored contact lens having a two-layer structure.
  • FIG. 4 is a photograph showing the contact lens shape in Example 4 and Comparative Example 4, wherein (a), (b), and (c) are 0 minutes and 20 minutes after the start of drying of the colored contact lens in Example 4, The lens shape after 45 minutes is shown, and (d), (e), and (f) are photographs showing the contact lens shape after 0 minutes, 20 minutes, and 45 minutes from the start of drying of the colored contact lens in Comparative Example 4. is there.
  • the present invention relates to a colored contact lens having a two-layer structure in the thickness direction in which the center thickness of the first polymer layer provided with the inner surface of the colored contact lens is a predetermined thickness, and a method for manufacturing the same.
  • the lower limit of the center thickness of the first polymer layer having the inner surface is 5 ⁇ m
  • the upper limit is 35% as the ratio of the center thickness of the first polymer layer having the inner surface to the center thickness of the colored contact lens.
  • the colored contact lens is manufactured through at least two polymerization steps so as to have a two-layer structure.
  • FIG. 1 illustrates a process of manufacturing a colored contact lens having a two-layer structure.
  • a female mold (1) having a concave molding surface and a male mold (2) having a convex molding surface are prepared.
  • the male mold or female mold used in the present invention is molded from a general-purpose thermoplastic resin.
  • polypropylene, polyethylene, polystyrene, polycarbonate, polyethylene terephthalate, polyamide, polyacetal, polyvinyl chloride, and nylon 6 can be used. Different resins can be appropriately selected from these resins to form each mold, or the same resin can be selected to form each mold.
  • the mold forming resin polypropylene, polystyrene, polyamide or the like is preferably used for reasons such as excellent price, transparency, and moldability.
  • a known method such as compression molding or vacuum molding can be appropriately employed as a method for forming each mold.
  • the female mold (1) is filled with the first lens forming material (3) of the lens (A-1 in FIG. 1).
  • the first lens forming material is polymerized in the space (4) formed in combination with the male mold (A-2 in FIG. 1).
  • the male mold and the female mold are opened (B in FIG. 1), and a light shielding material (6) is applied on the convex surface of the first polymer (5) fixed to the male mold. (C in FIG. 1).
  • the center thickness of the first polymer is defined by the distance between the male lens center point ( ⁇ ) and the female lens center point ( ⁇ ).
  • a female mold (1 ′) which is a mold that forms a pair with the mold on which the first polymer is fixed, is filled with the second lens forming material (3 ′) (D-1 in FIG. 1) and polymerized (FIG. 1). 1 D-2).
  • the center thickness of the second polymer is such that the lens center point ( ⁇ ′) of the female mold which is a mold in which the polymer is not fixed and the lens center of the exposed surface of the first polymer fixed to the male mold. It is defined by the distance to the point ( ⁇ ).
  • the female mold (1) is filled with the second lens forming material of the lens (A-1 in FIG.
  • the second lens forming material is polymerized in the space formed in combination with the male mold (A-2 in FIG. 2).
  • the male mold and the female mold are opened (B in FIG. 2), and a light shielding material is applied on the concave surface of the second polymer fixed to the female mold (C in FIG. 2).
  • the center thickness of the second polymer is defined by the distance between the male lens center point ( ⁇ ) and the female lens center point ( ⁇ ).
  • the first lens-forming material is filled on the fixed second polymer (D-1 in FIG. 2) and polymerized (D-2 in FIG. 2).
  • the center thickness of the first polymer is determined by the lens center point ( ⁇ ) of the male mold that is a mold in which the polymer is not fixed and the lens center point of the exposed surface of the second polymer fixed to the female mold. It is defined by the distance to ( ⁇ ′).
  • FIG. 1 is an example in which the paired mold is a female mold (third aspect of the present invention)
  • FIG. 2 is an example in which the paired mold is a male mold (fourth aspect of the present invention).
  • the female mold should be a new female mold that is not used if priority is given to the cleanliness of the concave surface of the female mold. In consideration of cost reduction, it is preferable to reuse the already used female mold.
  • the male mold should use a new male mold that is not used if priority is given to the cleanliness of the convex surface of the male mold. In consideration of cost reduction, it is preferable to reuse the already used male mold.
  • the first and second lens forming materials of the present invention are polymerizable compositions, and conventionally known monomers can be used.
  • hydroxyalkyl (meth) Acrylate especially hydroxyalkyl methacrylate: 2-HEMA
  • alkylene glycol mono (meth) acrylate especially hydroxyalkyl methacrylate: 2-HEMA
  • alkylene glycol mono (meth) acrylate alkylaminoalkyl (meth) acrylate, dimethyl (meth) acrylamide (especially dimethylacrylamide: DMAA)
  • glycerol (meth) acrylate especially glycerol
  • Examples include methacrylate: glycerol MA), glycidyl (meth) acrylate, vinyl pyrrolidone, and (meth) acrylic acid.
  • a monomer that gives a polymer having a low glass transition point such as n-butyl (meth) acrylate, decyl (meth) acrylate, or lauryl (meth) acrylate
  • a monomer such as a silicone-containing alkyl (meth) acrylate, a silicone-containing macromer, or the like can be used in combination with the above monomer.
  • None of the polymerizable compositions that are the first and second lens forming materials has an essential monomer, and the type, composition ratio, and the like can be appropriately selected according to the colored contact lens to be obtained.
  • (II) Created with the same mold material for male and female molds, and some kind of treatment (plasma treatment, UV irradiation, corona discharge treatment, laser irradiation or application of a surfactant, etc.) on the surface of one mold To increase the adhesive strength with the first polymer or to facilitate release.
  • a method of opening a mold so as to always be selectively fixed to one mold for example, a mold is opened with a temperature gradient from a male mold to a female mold, and the heat is low.
  • a method in which the first polymer remains selectively may be employed.
  • the adhesive surface between the surface of the first polymer or the second polymer and the male and female surfaces has an antisymmetric relationship (concave with respect to the convex surface, convex with respect to the concave surface).
  • the mold can be opened in a state of being selectively fixed to one of the molds.
  • the control method described above is a technique that enables more reliable control, and whether or not to adopt it may be determined from comprehensive judgment such as cost.
  • the space (4) in FIG. 1 is filled with the first lens forming material (3), but there are separate voids for accommodating an excessive amount of the first lens forming material. It may be formed when these are combined. By accommodating an excessive amount of the first lens forming material as a feeder, shrinkage that may occur during the polymerization process can be suppressed.
  • Other methods for avoiding shrinkage during polymerization include a method in which a non-reactive substance that does not participate in polymerization is added in advance to a polymerizable composition that is a lens-forming material, and male and / or female molds shrink. For example, there is a method of using a material molded with a material having sufficient flexibility to absorb.
  • one surface of the first polymer forms the inner surface of the colored contact lens
  • the other surface is a surface covered with the second polymer (7).
  • the surface to be coated with the second polymer does not necessarily have to have a precisely shaped surface, so the male or female mold that will form this surface has sufficient flexibility. It can be absorbed to absorb shrinkage during polymerization.
  • thermo polymerization by heating, photopolymerization irradiated with light such as ultraviolet rays, and a combination thereof can be mentioned.
  • the temperature is gradually raised from around room temperature, and heat in a temperature range of 30 ° C. to 120 ° C. is applied to the lens forming material within a few minutes to a few hours.
  • the thermal polymerization initiator persulfates, peroxides, azo initiators, and the like can be suitably used.
  • polymerization of the lens forming material proceeds by irradiation with active energy such as ultraviolet rays and electron beams.
  • active energy such as ultraviolet rays and electron beams.
  • an alkylphenone-based or acylphosphine oxide-based initiator can be suitably used.
  • the light shielding object (6) is applied to the exposed surface of the second polymer fixed to the female mold with a desired design to form a pattern by the light shielding object.
  • the design is composed of any one of dots, lines, planes, or a combination thereof, and can also represent characters, figures, symbols, iris patterns, etc. in addition to simply coloring.
  • a method for applying the light shielding pattern a conventional method can be appropriately employed, and screen printing, pad printing, ink jet printing, or the like can be employed.
  • Which coating method is selected is determined in consideration of the physical properties of the light shielding material, the characteristics of the second polymer, the state of the surface to be coated, and the like. After applying the light shield to the second polymer, it is desirable to fix the light shield to the second polymer so that the light shield is not dispersed when filling the first lens forming material. . There are various methods for fixing the light shield (heating, drying, electron beam irradiation, etc.), which can also be selected as appropriate (FIG. 3-i). After opening the male mold and the female mold, the light shielding object (6) is applied to the exposed surface of the first polymer fixed to the male mold with a desired design to form a pattern by the light shielding object. Is done.
  • the design is composed of any one of dots, lines, planes, or a combination thereof, and can also represent characters, figures, symbols, iris patterns, etc. in addition to simply coloring.
  • a method for applying the light shielding pattern a conventional method can be appropriately employed, and screen printing, pad printing, ink jet printing, or the like can be employed. Which coating method is selected is determined in consideration of the physical properties of the light shielding material, the characteristics of the first polymer, the state of the surface to be coated, and the like. After applying the light shield to the first polymer, it is desirable to fix the light shield to the first polymer so that the light shield is not dispersed when filling the second lens forming material. . There are various methods for fixing the light shield (heating, drying, electron beam irradiation, etc.), which can be selected as appropriate (FIG. 3-ii).
  • a pattern of light shielding material (for example, comprising a continuous transparent portion of the sea portion and a discontinuously colored opaque portion of the island portion) masking the color of the iris surrounding the transparent central visual region applied by the above printing method.
  • the pattern having a sea-island structure is a so-called layer having some thickness in the thickness direction of the colored contact lens between the first and second polymers. It is appropriate that the pattern of the light shielding object has a thickness of about 5 to 15 ⁇ m so that it has light shielding properties and can maintain the shape of the colored contact lens.
  • a colored transparent lens containing an opaque material can be manufactured.
  • coloring the entire colored contact lens in the same color it is only necessary to add a coloring component to the first and / or second lens forming material.
  • the production method of the present invention can be used effectively.
  • the first lens forming material and the second lens forming material are not necessarily different compositions as the lens forming material.
  • the same composition as the first lens forming material is applied to the second lens forming material after applying a light shielding material to the exposed surface of the first polymer. It is because it may be used as.
  • An example of combining different polymerizable compositions as lens forming materials is to produce colored contact lenses having different hardnesses of the respective polymer layers.
  • two-material contact lenses have been proposed in which the central portion is a hard contact lens and the peripheral portion is a soft contact lens.
  • the characteristics of these two kinds of contact lenses are that the central part is formed with a hard contact lens with excellent visual acuity correction power, and at the same time, the peripheral part is softened to improve the wearing feeling, and the advantages of the hard contact lens and the soft contact lens are improved. It was to provide a contact lens to have.
  • Various manufacturing methods have been proposed. Basically, the manufacturing method has a material distribution of a central portion and an annular peripheral portion. There are two problems with the two-material contact lens.
  • the wearer removes the worn contact lens
  • two is that the area where the dissimilar materials are joined together is small and the bonding between the dissimilar materials is weak.
  • the hard contact lens is removed by gathering the upper and lower eyelids toward the center. This is possible because the edge portion of the contact lens is hard.
  • the soft contact lens is bent so that the contact lens is sandwiched between the thumb and forefinger and removed from the eye.
  • the hard part does not get in the way to bend like a soft contact lens, and the peripheral part is soft, so the power of the eyelids is like a hard contact lens. It is also difficult to remove.
  • the soft contact lens is inferior in visual acuity correction power than the hard contact lens
  • the color contact lens inner surface side (BC side) layer of the present invention is manufactured as a hard layer
  • the contact lens outer surface side (FC side) layer is manufactured as a soft layer.
  • the hardness on the inner surface side of the contact lens prevents the contact lens from following the irregularities on the corneal surface, and corrects visual acuity by accumulating tear fluid between the inner surface of the contact lens and the cornea.
  • the contact lens outer surface side can be softened to maintain the feeling of wearing the contact lens, and the contact lens as a whole can be made flexible enough to be sandwiched when the contact lens is removed.
  • the colored contact lens of the present invention does not have a narrow joining area of different materials unlike the conventional two-type contact lens, and has a layered structure in the thickness direction.
  • the power is very high. In this way, it is possible to design a contact lens that is comprehensively excellent in terms of visual acuity correction power, wearing feeling, ease of contact lens removal, durability, and the like.
  • FIG. 4 shows a sectional view in the diameter direction of the two-layer colored contact lens.
  • the colored contact lens of the present invention has a colored portion between the first polymer having the inner surface of the contact lens having a predetermined center thickness and the other polymer layer. Recognize.
  • FIG. 3 (i) shows a color on the surface of the second polymer on the FC side
  • FIG. 3 (ii) shows a color on the surface of the first polymer on the BC side.
  • Example 1 The first lens forming material (2-hydroxyethyl methacrylate (HEMA) 59 w / w%, glycerol methacrylate 30 w / w%, ethylene glycol dimethacrylate 0.5 w / w%, glycerin 10 w / w on a female mold having a concave molding surface.
  • a plasma-treated male mold provided, irradiated with light (365 nm, 1 mW / cm 2 ) for 5 minutes from the female mold side in a nitrogen atmosphere, polymerized the lens forming material, and then separated both molds .
  • the obtained first polymer was attached to the male mold and had a shape similar to a colored contact lens.
  • the male mold and the female mold were designed so that a polymer layer having a front curvature radius of 6.6 mm, a rear curvature radius of 6.6 mm, a center thickness of 24 ⁇ m, and an outer diameter of 10.9 mm was obtained.
  • a light shielding material (2-HEMA 30 w / w%, iron oxide 40 w / w%, titanium oxide 20 w / w%, polyvinylpyrrolidone (PVP (K-30)) 10 w / w%) is exposed on the exposed surface of the first polymer.
  • PVP polyvinylpyrrolidone
  • 35 ⁇ l of a second lens forming material having the same composition as the first lens forming material is placed in a female mold that is paired with a male mold on which the first polymer is fixed, and the first polymer is left in a blower.
  • the attached male mold was fitted, and light (365 nm, 3 mW / cm 2 ) was irradiated from the female mold side for 5 minutes in a nitrogen atmosphere to polymerize the second lens forming material.
  • both molds were separated, the two-layer polymer in which the first polymer and the second polymer were joined adhered to the male mold.
  • the two-layer polymer contained water and was removed from the male mold.
  • the colored contact lens which is a two-layered polymer that has been removed from the male mold and softened with water and swelling, was immersed in 5 ml of fresh purified water for 10 minutes at room temperature.
  • the operation of immersing in fresh purified water 5 ml at room temperature for 10 minutes is repeated 5 times to remove the eluting components from the colored contact lens, and 1 colored contact lens is placed in a depression in a PP container containing 1 ml of physiological saline, The hollow of the container was sealed with the multilayer film, and autoclaved at 121 ° C.
  • the measuring method of the center thickness of the colored contact lens and the thickness of the colored part was performed as follows. Two razors with sharp teeth were aligned and fixed. When the fixed razor was pressed and cut at a position where the colored contact lens was divided into two equal parts, a strip-shaped lens piece having a width corresponding to the interval between the razor teeth aligned (about 50 ⁇ m) could be obtained. .
  • the lens piece is immersed in physiological saline in a plastic petri dish, and the thickness direction of the colored contact lens is photographed using a metal microscope (Nikon ECLIPSE ME600) and an illuminator (L-UEP1). In addition, the center thickness of the lens was calculated by comparing with the size of the reference ruled image taken in the same manner. Comparative Example 1 An attempt was made to produce colored contact lenses in the same manner as in Example 1. However, the thickness of the first polymer layer produced by the female mold and the male mold was designed to be 60 ⁇ m. The thickness of the polymer layer on the BC side became too thick, and 2 out of 8 defective products due to shape defects occurred.
  • the center thickness of one polymer layer including the inner surface of the lens was 60 ⁇ m, and the center thickness of the colored contact lens was 110 ⁇ m.
  • the method for measuring the center thickness of the lens was the same as in Example 1.
  • Example 2 23 ⁇ l of the same first lens forming material as in Example 1 was placed in a female mold and fitted with a plasma-treated male mold, and light (365 nm, 1 mW / cm 2 ) was applied for 5 minutes from the female mold side in a nitrogen atmosphere. Irradiated to polymerize the first lens forming material and separate the two molds. The obtained first polymer was attached to the male mold and had a lens-like shape. At this time, the male mold and the female mold were designed so that a polymer layer having a front curvature radius of 6.6 mm, a rear curvature radius of 6.6 mm, a center thickness of 15 ⁇ m, and an outer diameter of 10.9 mm was obtained.
  • a light shielding material (2-HEMA 30 w / w%, iron oxide 40 w / w%, titanium oxide 20 w / w%, PVP (K-30) 10 w / w%) on the exposed surface of the first polymer as in Example 1.
  • the second polymer is designed to have a lens shape with a center thickness of 40 ⁇ m and an outer diameter of 10.9 mm.
  • the two-layer polymer in which the first polymer and the second polymer were joined adhered to the male mold.
  • Eight lens-shaped two-layer polymers adhering to the male mold were plasma-treated in an oxygen atmosphere in a low-temperature ashing apparatus for 2 minutes and immersed in 5 ml of purified water, respectively. More off.
  • a colored contact lens which is a two-layered polymer that has been removed from the mold and became soft due to water content and swelling, was immersed in 5 ml of fresh purified water for 10 minutes at room temperature.
  • the operation of immersing in 5 ml of fresh purified water at room temperature for 10 minutes is repeated 5 times to remove the eluting components from the colored contact lens, and the colored contact is formed in the depression in the PP container containing 1 ml of physiological saline as in Example 1.
  • the lens was put in, the hollow of the container was sealed with the multilayer film, and autoclaved at 121 ° C. for 20 minutes. After cooling, the multilayer film was peeled off and the colored contact lens was inspected.
  • the colored contact made of a good silicone hydrogel material and a water-containing material having a power of ⁇ 3.0D, a diameter of 14.2 mm, and a center thickness of 110 ⁇ m. Eight lenses were obtained.
  • the center thickness of the first polymer layer provided with the inner surface of the lens was 15 ⁇ m.
  • the method for measuring the center thickness of the colored contact lens was the same as in Example 1. Comparative Example 2 An attempt was made to produce colored contact lenses in the same manner as in Example 2. However, the thickness of the first polymer layer was designed to be 60 ⁇ m. An attempt was made to produce a colored contact lens of -3.0D, but the size of the finished colored contact lens was unstable, and 3 out of 8 out of specifications occurred.
  • the measuring method of the center thickness of a lens and the center thickness of the 1st polymer layer provided with a lens inner surface was performed similarly to Example 1. FIG.
  • Example 3 Using the same first and second forming materials as in Example 1, a colored contact lens having a center thickness T1 of the colored contact lens and a thickness T2 of the first polymer provided with the inner surface of the colored contact lens was obtained (frequency ⁇ 3.0D, diameter 14.2 mm). The thickness of the colored layer was about 10 ⁇ m. A colored contact lens having a lens center thickness of 50 ⁇ m or more and less than 80 ⁇ m, wherein T1 / T2 which is a ratio of the center thickness of the first polymer layer provided with the inner surface of the colored contact lens to the center thickness of the colored contact lens is 35% or less. The colored contact lenses that were obtained are shown in Table 1 as Example 3-1 and Example 3-2.
  • colored contact lenses having a colored contact lens center thickness of 80 ⁇ m or more and 200 ⁇ m or less and T2 of 40 ⁇ m or less are shown as Example 3-3, Example 3-4 and Example 3-5 in Table 1. It was shown to. Table 1 shows the state of the strip-shaped lens pieces cut out from these hydrated colored contact lenses in the same manner as in Example 1 in physiological saline. When the shape of the strip-shaped lens piece remains the same as that of the colored contact lens before cutting, ⁇ , when it is almost flat, it is warped against the lens shape before cutting. ⁇ when curled, and x when curled.
  • Comparative Example 3 Using the same first and second forming materials as in Example 1, a colored contact lens having a central thickness T1 of the colored contact lens and a thickness T2 of the first polymer layer provided with the colored contact lens inner surface was obtained (frequency) -3.0D, diameter 14.2 mm). The thickness of the colored layer was about 10 ⁇ m. Colored contact lenses having a lens center thickness of 50 ⁇ m or more and less than 80 ⁇ m and having T1 / T2 of more than 35% are shown in Table 1 as Comparative Example 3-1 and Comparative Example 3-2. Further, colored contact lenses having a lens center thickness of 80 ⁇ m or more and 200 ⁇ m or less and T2 exceeding 40 ⁇ m are shown in Table 1 as Comparative Example 3-3 and Comparative Example 3-4.
  • Example 3 The state of the strip-shaped lens pieces cut out from these hydrated colored contact lenses in the same manner as in Example 1 in physiological saline was evaluated in the same manner as in Example 3 and shown in Table 1.
  • the cut-out strip-shaped lens piece maintains an appropriate lens shape, and it is estimated that the stress due to the molding method does not remain in the colored contact lens. It was.
  • the colored contact lens indicated by ⁇ or ⁇ in Comparative Example 3 shows that even if it is in an appropriate lens shape before cutting, the cut-out strip-shaped lens piece cannot retain the lens shape before cutting, and coloring It was estimated that the stress due to the mold manufacturing method remained on the contact lens.
  • Example 4 An experiment was conducted to examine the retention of the contact lens shape when the contact lens was in a dry state.
  • 2 g of cobalt chloride (2) hexahydrate (Nacalai tex) was weighed and dissolved in 8 ml of purified water (Kyoei Pharmaceutical) to prepare a 20 w / v% solution.
  • T1 110 ⁇ m
  • T2 20 ⁇ m
  • the colored contact lens In the colored contact lens, with the discoloration (blue) of the cobalt chloride reagent indicating the dry state, the lens edge bent to the BC side, and the shape of the entire contact lens changed to an irregular shape. On the other hand, the lens shape hardly changed in other cases.
  • the colored contact lens of the present invention is a contact by a mold manufacturing method that is not colored. As with the lens, it was found that even when the dry state progressed, the lens shape retention was excellent.
  • T1 73 ⁇ m
  • T2 62 ⁇ m
  • power ⁇ 9.0D diameter 14.2 mm
  • BC 8.5 mm the thickness of the colored layer in the colored contact lens and the colored (with iris) contact lens was about 10 ⁇ m.
  • the present invention relates to a colored contact lens having a two-layer structure in the thickness direction and a method for producing the same, and the shape of the lens is obtained by setting the center thickness of a first polymer layer provided with the inner surface of the colored contact lens to a predetermined thickness.

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Manufacturing & Machinery (AREA)
  • Mechanical Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Eyeglasses (AREA)
  • Casting Or Compression Moulding Of Plastics Or The Like (AREA)

Abstract

La présente invention concerne une lentille de contact colorée ayant une épaisseur centrale de 80 à 200 µm, comprenant : une première couche polymère comportant une surface intérieure de la lentille de contact, dotée d'une épaisseur centrale de 5 à 40 µm ; une seconde couche polymère comportant une surface extérieure de la lentille de contact ; et un motif bloquant la lumière, situé entre les deux couches polymères. La présente invention concerne également une lentille de contact colorée ayant une épaisseur centrale de 50 µm au minimum et de 80 µm au maximum, comprenant : une première couche polymère comportant une surface intérieure de la lentille de contact, dotée d'une épaisseur centrale limite basse de 5 µm et d'une épaisseur centrale limite haute de 35 % de l'épaisseur centrale de la lentille de contact ; une seconde couche polymère comportant une surface extérieure de la lentille de contact ; et un motif bloquant la lumière, situé entre les deux couches polymères.
PCT/JP2013/080014 2012-11-09 2013-11-06 Lentille de contact colorée à couche mince de côté face intérieure et son procédé de fabrication WO2014073568A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2014545732A JPWO2014073568A1 (ja) 2012-11-09 2013-11-06 内面側層が薄い着色コンタクトレンズ及びその製造方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012247402 2012-11-09
JP2012-247402 2012-11-09

Publications (1)

Publication Number Publication Date
WO2014073568A1 true WO2014073568A1 (fr) 2014-05-15

Family

ID=50684670

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2013/080014 WO2014073568A1 (fr) 2012-11-09 2013-11-06 Lentille de contact colorée à couche mince de côté face intérieure et son procédé de fabrication

Country Status (2)

Country Link
JP (1) JPWO2014073568A1 (fr)
WO (1) WO2014073568A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3213229U (ja) * 2017-08-14 2017-10-26 視茂股▲ふん▼有限公司 深層カバー式コンタクトレンズ
JP2018103600A (ja) * 2016-07-28 2018-07-05 株式会社キヨシ・ネットワーク アニロックスロール洗浄装置
WO2019078231A1 (fr) 2017-10-18 2019-04-25 株式会社シード Procédé de fabrication de lentille ophtalmique dans laquelle est incorporé un élément
WO2021092038A1 (fr) 2019-11-06 2021-05-14 Innovega Inc. Appareils et procédés de moulage multi-étapes de lentilles
JP2023044605A (ja) * 2021-09-17 2023-03-30 ペガヴィジョン コーポレーション コンタクトレンズ及びその製造方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02181723A (ja) * 1988-11-16 1990-07-16 Ciba Geigy Ag 着色されたコンタクトレンズ及びその製造方法
JPH04264517A (ja) * 1990-10-30 1992-09-21 Pilkington Visioncare Inc コンタクトレンズ
JP2005531810A (ja) * 2002-06-28 2005-10-20 ボシュ・アンド・ロム・インコーポレイテッド カラー部分およびコーティング表面を有するレンズ
JP2009008848A (ja) * 2007-06-27 2009-01-15 Nippon Optical:Kk コンタクトレンズとその製造方法
JP2010529505A (ja) * 2007-06-07 2010-08-26 ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド 奥行き効果を有する着色コンタクトレンズ
JP2013242450A (ja) * 2012-05-22 2013-12-05 Menicon Nect:Kk 眼用レンズの製造方法及び眼用レンズ

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102985871B (zh) * 2010-06-21 2015-09-30 目立康株式会社 彩色隐形眼镜

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02181723A (ja) * 1988-11-16 1990-07-16 Ciba Geigy Ag 着色されたコンタクトレンズ及びその製造方法
JPH04264517A (ja) * 1990-10-30 1992-09-21 Pilkington Visioncare Inc コンタクトレンズ
JP2005531810A (ja) * 2002-06-28 2005-10-20 ボシュ・アンド・ロム・インコーポレイテッド カラー部分およびコーティング表面を有するレンズ
JP2010529505A (ja) * 2007-06-07 2010-08-26 ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド 奥行き効果を有する着色コンタクトレンズ
JP2009008848A (ja) * 2007-06-27 2009-01-15 Nippon Optical:Kk コンタクトレンズとその製造方法
JP2013242450A (ja) * 2012-05-22 2013-12-05 Menicon Nect:Kk 眼用レンズの製造方法及び眼用レンズ

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018103600A (ja) * 2016-07-28 2018-07-05 株式会社キヨシ・ネットワーク アニロックスロール洗浄装置
JP3213229U (ja) * 2017-08-14 2017-10-26 視茂股▲ふん▼有限公司 深層カバー式コンタクトレンズ
WO2019078231A1 (fr) 2017-10-18 2019-04-25 株式会社シード Procédé de fabrication de lentille ophtalmique dans laquelle est incorporé un élément
JPWO2019078231A1 (ja) * 2017-10-18 2019-11-14 株式会社シード 部材を埋入した眼用レンズの製造方法
CN111328381A (zh) * 2017-10-18 2020-06-23 株式会社实瞳 埋入了部件的眼用镜片的制造方法
CN111328381B (zh) * 2017-10-18 2021-08-24 株式会社实瞳 埋入了部件的眼用镜片的制造方法
WO2021092038A1 (fr) 2019-11-06 2021-05-14 Innovega Inc. Appareils et procédés de moulage multi-étapes de lentilles
EP4055439A4 (fr) * 2019-11-06 2023-12-27 Innovega Inc. Appareils et procédés de moulage multi-étapes de lentilles
JP2023044605A (ja) * 2021-09-17 2023-03-30 ペガヴィジョン コーポレーション コンタクトレンズ及びその製造方法

Also Published As

Publication number Publication date
JPWO2014073568A1 (ja) 2016-09-08

Similar Documents

Publication Publication Date Title
JP5621117B2 (ja) 多層コンタクトレンズおよびその製造方法
WO2014073568A1 (fr) Lentille de contact colorée à couche mince de côté face intérieure et son procédé de fabrication
KR880002451B1 (ko) 연속변화성 다촛점 소프트 콘택트렌즈 및 그 제조방법
CN105142886B (zh) 制造具有嵌入式掩膜的人工晶状体的方法
JP5369273B1 (ja) 着色コンタクトレンズ
JP2009008848A (ja) コンタクトレンズとその製造方法
KR20070009585A (ko) 하이브리드 콘택트렌즈 시스템 및 방법
JP2023164574A (ja) 眼用レンズの付加的な製造方法、及び眼用レンズ
KR20160047529A (ko) 초박형 광학 부분품을 포함하는 안과용 렌즈의 제조 방법 및 그러한 렌즈
JPH06170857A (ja) コンタクトレンズの製造方法およびそれに用いられる成形型
KR101190303B1 (ko) 플루시어 공법을 적용하여 채색부가 렌즈 내부에 함입된 착색 콘택트렌즈를 제조하는 방법 및 이에 의하여 제조된 착색 콘택트렌즈
JP6155457B2 (ja) 多層コンタクトレンズおよびその製造方法
JP5621118B2 (ja) 着色コンタクトレンズおよびその製造方法
US11543684B2 (en) Non-corrective plastic spectacle lens
WO2012102332A1 (fr) Corps correcteur de presbytie et procédé de correction de presbytie
US10175509B2 (en) Spectacle lens
JPS6361225A (ja) 眼用レンズの製造方法
TW202014763A (zh) 具有圖案的隱形眼鏡
JP3179308U (ja) 老眼矯正コンタクトレンズ
TWI844287B (zh) 訂製型散光隱形眼鏡
WO2020077619A1 (fr) Lentille de contact ayant un motif
KR20240119257A (ko) 오그제틱 필름을 구비하는 필름 구조물을 포함하는 안과용 요소
JP5936055B2 (ja) 矯正コンタクトレンズの製造方法
CN108803077A (zh) 一种色盲色弱矫正隐形眼镜及其制作方法
JP2012155295A (ja) 老眼矯正体及び老眼矯正方法

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13853293

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2014545732

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 13853293

Country of ref document: EP

Kind code of ref document: A1