WO2012121560A3 - 난청의 예방 또는 치료용 조성물 - Google Patents

난청의 예방 또는 치료용 조성물 Download PDF

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Publication number
WO2012121560A3
WO2012121560A3 PCT/KR2012/001711 KR2012001711W WO2012121560A3 WO 2012121560 A3 WO2012121560 A3 WO 2012121560A3 KR 2012001711 W KR2012001711 W KR 2012001711W WO 2012121560 A3 WO2012121560 A3 WO 2012121560A3
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Prior art keywords
hearing loss
preventing
present
dodder
treating
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PCT/KR2012/001711
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English (en)
French (fr)
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WO2012121560A2 (ko
WO2012121560A9 (ko
Inventor
강동호
홍빛나
Original Assignee
경희대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 경희대학교 산학협력단 filed Critical 경희대학교 산학협력단
Priority to US14/002,763 priority Critical patent/US20130337089A1/en
Priority to CN201280012357.0A priority patent/CN103402528B/zh
Publication of WO2012121560A2 publication Critical patent/WO2012121560A2/ko
Publication of WO2012121560A9 publication Critical patent/WO2012121560A9/ko
Publication of WO2012121560A3 publication Critical patent/WO2012121560A3/ko
Priority to US14/925,265 priority patent/US9694043B2/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/64—Orobanchaceae (Broom-rape family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

본 발명은 토사자 추출물 또는 지황과 토사자 추출물을 포함하는 난청의 예방 또는 치료용 약학 조성물을 제공한다. 또한, 본 발명은 토사자 추출물 또는 지황과 토사자 추출물을 포함하는 난청의 예방 또는 개선용 식품 조성물을 제공한다. 본 발명에 따른 조성물은 소음 등으로 인한 청력 역치의 상승을 효과적으로 억제시킴으로써, 난청 특히 음향 외상성, 일시적 또는 영구적 소음성 난청을 억제할 수 있다. 따라서, 본 발명에 따른 조성물은 난청의 예방 또는 치료에 효과적이다. 또한, 경구투여가 가능하여 환자의 복약 순응도를 높일 수 있다.
PCT/KR2012/001711 2011-03-10 2012-03-08 난청의 예방 또는 치료용 조성물 WO2012121560A2 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US14/002,763 US20130337089A1 (en) 2011-03-10 2012-03-08 Composition for preventing or treating hearing loss
CN201280012357.0A CN103402528B (zh) 2011-03-10 2012-03-08 用于预防或治疗听力损失的组合物
US14/925,265 US9694043B2 (en) 2011-03-10 2015-10-28 Composition for preventing or treating hearing loss

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020110021389A KR101720054B1 (ko) 2011-03-10 2011-03-10 난청의 예방 또는 치료용 조성물
KR10-2011-0021389 2011-03-10

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US14/002,763 A-371-Of-International US20130337089A1 (en) 2011-03-10 2012-03-08 Composition for preventing or treating hearing loss
US14/925,265 Continuation US9694043B2 (en) 2011-03-10 2015-10-28 Composition for preventing or treating hearing loss

Publications (3)

Publication Number Publication Date
WO2012121560A2 WO2012121560A2 (ko) 2012-09-13
WO2012121560A9 WO2012121560A9 (ko) 2012-11-01
WO2012121560A3 true WO2012121560A3 (ko) 2012-12-27

Family

ID=46798661

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/001711 WO2012121560A2 (ko) 2011-03-10 2012-03-08 난청의 예방 또는 치료용 조성물

Country Status (4)

Country Link
US (2) US20130337089A1 (ko)
KR (1) KR101720054B1 (ko)
CN (1) CN103402528B (ko)
WO (1) WO2012121560A2 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150050364A1 (en) * 2012-04-18 2015-02-19 University-Industry Cooperation Group Of Kyung Hee University Composition for treating or preventing tinnitus
EP2861207A2 (en) 2012-06-18 2015-04-22 The Procter & Gamble Company Method of improving the appearance of aging skin
CN104337951A (zh) * 2013-08-10 2015-02-11 李谊 一种治疗噪声性耳聋的中药组合物
WO2017117701A1 (zh) * 2016-01-04 2017-07-13 葡萄王生技股份有限公司 预防听力退化的活性物质、含其的组合物、及其制备方法
KR102035845B1 (ko) * 2018-05-31 2019-10-23 경희대학교 산학협력단 난청의 예방 또는 치료용 조성물

Citations (3)

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Publication number Priority date Publication date Assignee Title
KR20020074285A (ko) * 2001-03-19 2002-09-30 퓨리메드 주식회사 숙지황 추출물을 포함하는 기억력 향상 생약조성물, 그제조방법 및 상기 숙지황 추출물을 함유한 건강보조식품및 식품첨가제
US20090246186A1 (en) * 2006-03-29 2009-10-01 Kaneka Corporation Agent for improving nervous system cell functions
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Also Published As

Publication number Publication date
US20160045558A1 (en) 2016-02-18
KR20120103237A (ko) 2012-09-19
KR101720054B1 (ko) 2017-03-27
CN103402528A (zh) 2013-11-20
WO2012121560A2 (ko) 2012-09-13
US9694043B2 (en) 2017-07-04
WO2012121560A9 (ko) 2012-11-01
CN103402528B (zh) 2016-08-10
US20130337089A1 (en) 2013-12-19

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