WO2012113906A2 - Solid support and method of enhancing the recovery of biological material therefrom - Google Patents

Solid support and method of enhancing the recovery of biological material therefrom Download PDF

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Publication number
WO2012113906A2
WO2012113906A2 PCT/EP2012/053163 EP2012053163W WO2012113906A2 WO 2012113906 A2 WO2012113906 A2 WO 2012113906A2 EP 2012053163 W EP2012053163 W EP 2012053163W WO 2012113906 A2 WO2012113906 A2 WO 2012113906A2
Authority
WO
WIPO (PCT)
Prior art keywords
solid support
paper
biological material
recovery
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2012/053163
Other languages
English (en)
French (fr)
Other versions
WO2012113906A3 (en
Inventor
Jeffrey Kenneth Horton
Peter James TATNELL
Simon Laurence John Stubbs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare UK Ltd
Original Assignee
GE Healthcare UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare UK Ltd filed Critical GE Healthcare UK Ltd
Priority to CA2828158A priority Critical patent/CA2828158C/en
Priority to AU2012219482A priority patent/AU2012219482B2/en
Priority to CN201280010442.3A priority patent/CN103460051B/zh
Priority to EP12705857.6A priority patent/EP2678692B1/en
Priority to JP2013554907A priority patent/JP6074369B2/ja
Priority to ES12705857.6T priority patent/ES2592963T3/es
Priority to US13/985,089 priority patent/US10876938B2/en
Publication of WO2012113906A2 publication Critical patent/WO2012113906A2/en
Publication of WO2012113906A3 publication Critical patent/WO2012113906A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/38—Pediatrics
    • G01N2800/385—Congenital anomalies

Definitions

  • the present invention relates to solid supports and is particularly concerned with solid supports which can be used in the storage, recovery and further processing of biological materials such as biopharmaceutical drugs.
  • solid supports which provide a simple, stable storage medium for biological materials, including i) endogenous moieties and ii) biopharmaceutical or biotech drugs, which give a high yield or recovery of the biological material on further processing.
  • the present invention addresses these needs and provides methods that enhance the recovery levels of biological materials such as biopharmaceutical drugs from biological samples stored as DBS on solid supports, particularly solid paper supports.
  • the biological material is selected from the group consisting of biomolecule, synthetically- derived biomolecule, cellular component and biopharmaceutical drug.
  • PEI Poly-ethyl-enemine

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Sampling And Sample Adjustment (AREA)
PCT/EP2012/053163 2011-02-25 2012-02-24 Solid support and method of enhancing the recovery of biological material therefrom Ceased WO2012113906A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CA2828158A CA2828158C (en) 2011-02-25 2012-02-24 Solid support and method of enhancing the recovery of biological material therefrom
AU2012219482A AU2012219482B2 (en) 2011-02-25 2012-02-24 Solid support and method of enhancing the recovery of biological material therefrom
CN201280010442.3A CN103460051B (zh) 2011-02-25 2012-02-24 固体支持物和提高生物材料从其中的回收率的方法
EP12705857.6A EP2678692B1 (en) 2011-02-25 2012-02-24 Solid support and method of enhancing the recovery of biological material therefrom
JP2013554907A JP6074369B2 (ja) 2011-02-25 2012-02-24 固体支持体、及びそこからの生物学的材料の回収率を高める方法
ES12705857.6T ES2592963T3 (es) 2011-02-25 2012-02-24 Soporte sólido y método para aumentar la recuperación de material biológico del mismo
US13/985,089 US10876938B2 (en) 2011-02-25 2012-02-24 Solid support and method of enhancing the recovery of biological material therefrom

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1103258.8A GB201103258D0 (en) 2011-02-25 2011-02-25 Solid support and method of enhancing the recovery of biological material therefrom
GB1103258.8 2011-02-25

Publications (2)

Publication Number Publication Date
WO2012113906A2 true WO2012113906A2 (en) 2012-08-30
WO2012113906A3 WO2012113906A3 (en) 2012-12-20

Family

ID=43904184

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2012/053163 Ceased WO2012113906A2 (en) 2011-02-25 2012-02-24 Solid support and method of enhancing the recovery of biological material therefrom

Country Status (9)

Country Link
US (1) US10876938B2 (https=)
EP (1) EP2678692B1 (https=)
JP (1) JP6074369B2 (https=)
CN (1) CN103460051B (https=)
AU (1) AU2012219482B2 (https=)
CA (1) CA2828158C (https=)
ES (1) ES2592963T3 (https=)
GB (1) GB201103258D0 (https=)
WO (1) WO2012113906A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3233128A4 (en) * 2014-12-18 2018-05-23 GE Healthcare UK Limited Analyte detection on a solid support by nucleic acid amplification coupled to an immunoassay
US10638963B2 (en) 2017-01-10 2020-05-05 Drawbridge Health, Inc. Devices, systems, and methods for sample collection
US11266337B2 (en) 2015-09-09 2022-03-08 Drawbridge Health, Inc. Systems, methods, and devices for sample collection, stabilization and preservation

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3521828A1 (en) * 2018-01-31 2019-08-07 Centogene AG Method for the diagnosis of hereditary angioedema
US20250085283A1 (en) * 2022-03-23 2025-03-13 Teijin Limited Method for quantifying nicotinamide adenine dinucleotide (nad+) or nicotinamide mononucleotide (nmn), and kit and filter paper for performing the method
WO2025249073A1 (ja) * 2024-05-30 2025-12-04 国立大学法人大阪大学 目的化合物を選択的に採取するためのデバイス、該デバイスの製造方法、および生体または環境試料から目的化合物を選択的に採取するための方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US575126A (en) 1897-01-12 Watch-pocket guard
US5939259A (en) 1997-04-09 1999-08-17 Schleicher & Schuell, Inc. Methods and devices for collecting and storing clinical samples for genetic analysis

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE542544A (https=) * 1954-11-04
US3227075A (en) 1961-04-04 1966-01-04 Fitchburg Paper Planographic printing plates
JPS5319092A (en) 1976-11-08 1978-02-21 Shionogi Seiyaku Kk Composite for liver desease detection
JPH01291164A (ja) 1988-05-19 1989-11-22 Fujirebio Inc 標準瀘紙用組成物
US5756126A (en) 1991-05-29 1998-05-26 Flinders Technologies Pty. Ltd. Dry solid medium for storage and analysis of genetic material
US5985327A (en) 1988-10-05 1999-11-16 Flinders Technologies Pty. Ltd. Solid medium and method for DNA storage
US5188938A (en) * 1988-12-29 1993-02-23 Microgenics Corporation Enzyme quantitation wicking assay
US5756362A (en) 1993-10-12 1998-05-26 Cornell Research Foundation, Inc. Liposome-enhanced immunoaggregation assay and test device
US6132971A (en) * 1995-06-27 2000-10-17 The University Of North Carolina At Chapel Hill Microelectronic device
US5804684A (en) * 1995-08-24 1998-09-08 The Theobald Smith Research Institute, Inc. Method for isolating nucleic acids
JPH10179722A (ja) 1996-12-25 1998-07-07 Sumitomo Bakelite Co Ltd 表面処理
DE69938774D1 (de) * 1998-02-02 2008-07-03 Qiagen North American Holdings Verfahren zur isolierung, amplifizierung und charakterisierung von dns
US6187540B1 (en) * 1998-11-09 2001-02-13 Identigene, Inc. Method of newborn identification and tracking
AU6048199A (en) 1999-03-11 2000-09-28 Whatman, Inc. Solid medium and process for the storage and rapid purification of nucleic acid
WO2003020924A2 (en) 2001-09-05 2003-03-13 Whatman Plc Stable storage of proteins
US20030215358A1 (en) * 2002-01-15 2003-11-20 Schulman Lloyd S. Liquid permeable composition in dry reagent devices
US7156945B2 (en) * 2002-04-24 2007-01-02 Sipix Imaging, Inc. Process for forming a patterned thin film structure for in-mold decoration
ES2320875T5 (es) * 2002-10-04 2012-10-30 Ge Healthcare Bio-Sciences Corp. Procedimientos y materiales para utilizar compuestos químicos como herramienta para el almacenamiento de ácidos nucleicos sobre medios de sistemas de purificación de ácidos nucleicos
US20110059441A1 (en) * 2007-04-16 2011-03-10 Mcmaster University Methof of producing bioactive paper
US7521021B2 (en) * 2003-11-26 2009-04-21 Leica Biosvstems St. Louis Llc System for in situ processing of a tissue specimen
US7045295B2 (en) 2004-04-02 2006-05-16 Hematologics, Inc. Method for collecting purified cells
CN1980738A (zh) * 2004-04-09 2007-06-13 科研智囊团有限公司 用于收集、储存和运输生物样本的设备和方法
US8062901B2 (en) * 2005-04-30 2011-11-22 Alere Switzerland Gmbh Devices and methods for sample collection and analysis
CA2625638C (en) * 2005-11-08 2014-03-11 Surmodics, Inc. Ultra-thin photo-polymer coatings and uses thereof
CN101892290A (zh) * 2009-05-19 2010-11-24 北京协和洛克生物技术研究开发中心 苯丙氨酸定量检测试剂盒(酶定量法)

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US575126A (en) 1897-01-12 Watch-pocket guard
US5939259A (en) 1997-04-09 1999-08-17 Schleicher & Schuell, Inc. Methods and devices for collecting and storing clinical samples for genetic analysis

Non-Patent Citations (19)

* Cited by examiner, † Cited by third party
Title
"IATA Dangerous Goods Regulations", 11 March 2005, ADDENDUM
BARFIELD, M. ET AL., ANAL., CHEM., vol. 83, 2011, pages 118 - 124
BEAUDETTE, P. ET AL., J. OF CHROMATOGRAPHY B, vol. 809, 2004, pages 153 - 158
BURHENNE, J. ET AL., J. CHROM B, ANAL. TECH BIOMED & LIFE SCI, vol. 863, 2008, pages 273 - 282
DENNIFF, P. ET AL., BIOANALYSIS, vol. 2, no. 11, 2010, pages 1817 - 22
ELVERS L ET AL., J. INHERIT MEDTAB DIS, vol. 30, no. 4, 2007, pages 609
GARCIA-BOY, R. ET AL., THERAPEUTIC DRUG MONITORING, vol. 30, no. 6, 2008, pages 733 - 739
HIGASHI, T. ET AL., J. PHARM AND BIOMEDICAL ANALYSIS, vol. 48, no. 1, 2008, pages 177 - 182
HOWE, C. ET AL., CLIN CHEM., vol. 43, 1997, pages 1408 - 15
JOHANNESSEN, A. ET AL., J ANTIMICROBIAL CHEMOTHERAPY, vol. 64, 2009, pages 1126 - 1129
KEHLER, R. ET AL., BIOANALYSIS, vol. 2, no. 8, 2010, pages 1461 - 1468
LIANG, X. ET AL., J. CHROM B, ANAL. TECH BIOMED & LIFE SCI, vol. 877, 2009, pages 799 - 806
LINDAU-SHEPARD; PASS, CLINICAL CHEM., vol. 56, 2010, pages 445 - 450
MEI, J. ET AL., JOURNAL OF NUTRITION, vol. 131, 2001, pages 1631 S - 1636S
NEWMAN, M. ET AL., J DIABETES SCI AND TECH., vol. 3, 2009, pages 156 - 162
RYLEY ET AL., J. CLIN. PATHOL., vol. 34, 1981, pages 906 - 910
SPOONER, N. ET AL., ANAL CHEM., vol. 81, 2009, pages 1557 - 63
VAN BERKEL, G. ET AL., ANAL., CHEM., vol. 81, no. 21, 2009, pages 9146 - 9152
WEGNER, I. ET AL., EPILEPSIA, vol. 51, 2010, pages 2500 - 2502

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3233128A4 (en) * 2014-12-18 2018-05-23 GE Healthcare UK Limited Analyte detection on a solid support by nucleic acid amplification coupled to an immunoassay
US11008604B2 (en) 2014-12-18 2021-05-18 Global Life Sciences Solutions Operations UK Ltd Analyte detection on a solid support by nucleic acid amplification coupled to an immunoassay
US11266337B2 (en) 2015-09-09 2022-03-08 Drawbridge Health, Inc. Systems, methods, and devices for sample collection, stabilization and preservation
US10638963B2 (en) 2017-01-10 2020-05-05 Drawbridge Health, Inc. Devices, systems, and methods for sample collection
US10888259B2 (en) 2017-01-10 2021-01-12 Drawbridge Health, Inc. Cartridge assemblies for storing biological samples
US10932710B2 (en) 2017-01-10 2021-03-02 Drawbridge Health, Inc. Carriers for storage and transport of biological samples
US11298060B2 (en) 2017-01-10 2022-04-12 Drawbridge Health, Inc. Devices for collecting biological samples

Also Published As

Publication number Publication date
JP6074369B2 (ja) 2017-02-01
ES2592963T3 (es) 2016-12-02
AU2012219482B2 (en) 2016-10-27
WO2012113906A3 (en) 2012-12-20
CN103460051B (zh) 2015-10-07
JP2014512516A (ja) 2014-05-22
US20130330750A1 (en) 2013-12-12
EP2678692A2 (en) 2014-01-01
US10876938B2 (en) 2020-12-29
CA2828158C (en) 2021-10-26
CA2828158A1 (en) 2012-08-30
EP2678692B1 (en) 2016-06-22
GB201103258D0 (en) 2011-04-13
AU2012219482A1 (en) 2013-08-29
CN103460051A (zh) 2013-12-18

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