WO2012093787A3 - 플로로글루시놀, 플로로탄닌 또는 갈조류 추출물을 포함하는 가바 ａ형-벤조다이아제핀 수용체 활성용 조성물 및 불안 완화, 경련 개선, 진정 작용, 및 수면 유도 및 개선용 조성물 - Google Patents

플로로글루시놀, 플로로탄닌 또는 갈조류 추출물을 포함하는 가바 ａ형-벤조다이아제핀 수용체 활성용 조성물 및 불안 완화, 경련 개선, 진정 작용, 및 수면 유도 및 개선용 조성물 Download PDF

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Publication number
WO2012093787A3
WO2012093787A3 PCT/KR2011/009916 KR2011009916W WO2012093787A3 WO 2012093787 A3 WO2012093787 A3 WO 2012093787A3 KR 2011009916 W KR2011009916 W KR 2011009916W WO 2012093787 A3 WO2012093787 A3 WO 2012093787A3
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Prior art keywords
composition
phlorotannin
convulsion
brown algae
algae extract
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PCT/KR2011/009916
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English (en)
French (fr)
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WO2012093787A2 (ko
Inventor
조승목
한대석
김동수
진영호
백남인
한진규
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한국식품연구원
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Priority claimed from KR1020110113356A external-priority patent/KR101260696B1/ko
Application filed by 한국식품연구원 filed Critical 한국식품연구원
Priority to JP2013547313A priority Critical patent/JP2014505683A/ja
Publication of WO2012093787A2 publication Critical patent/WO2012093787A2/ko
Publication of WO2012093787A3 publication Critical patent/WO2012093787A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Anesthesiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

본 발명은 플로로글루시놀, 플로로탄닌 또는 갈조류 추출물을 유효성분으로 하는 GABAA-벤조다이아제핀 수용체 활성용 조성물로서, 갈조류 추출물은 GABAA-벤조다이아제핀 수용체에 친화력을 가지는 것으로, 천연물로부터 얻어진 물질을 이용하기 때문에 부작용을 유발하지 않고, 안전성을 확보할 수 있으며, 플로로글루시놀, 플로로탄닌 또는 갈조류 추출물을 유효성분으로 항불안, 항경련(anti-convulsant), 진정 및 불면증 치료용 약학 조성물이나 불안 완화, 경련 개선, 진정 작용, 및 수면 유도 및 개선용 식품 조성물으로 활용될 수 있다.
PCT/KR2011/009916 2011-01-03 2011-12-21 플로로글루시놀, 플로로탄닌 또는 갈조류 추출물을 포함하는 가바 ａ형-벤조다이아제핀 수용체 활성용 조성물 및 불안 완화, 경련 개선, 진정 작용, 및 수면 유도 및 개선용 조성물 WO2012093787A2 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2013547313A JP2014505683A (ja) 2011-01-03 2011-12-21 フロログルシノール、フロロタンニンまたは褐藻類抽出物を含むギャバａ型−ベンゾジアゼピン受容体活性用組成物、及び抗不安、抗痙攣、鎮静作用、及び睡眠誘導及び改善用組成物

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
KR20110000196 2011-01-03
KR10-2011-0000196 2011-01-03
KR10-2011-0113355 2011-11-02
KR10-2011-0113356 2011-11-02
KR1020110113356A KR101260696B1 (ko) 2011-01-03 2011-11-02 갈조류 추출물을 포함하는 가바 ａ형－벤조다이아제핀 수용체 활성용 조성물 및 불안 완화, 경련 개선, 진정 작용, 및 수면 유도 및 개선용 조성물
KR1020110113355A KR101260697B1 (ko) 2011-01-03 2011-11-02 플로로글루시놀 또는 플로로탄닌을 포함하는 가바 ａ형-벤조다이아제핀 수용체 활성용 조성물 및 불안 완화, 경련 개선, 진정 작용, 및 수면 유도 및 개선용 조성물

Publications (2)

Publication Number Publication Date
WO2012093787A2 WO2012093787A2 (ko) 2012-07-12
WO2012093787A3 true WO2012093787A3 (ko) 2012-09-07

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PCT/KR2011/009916 WO2012093787A2 (ko) 2011-01-03 2011-12-21 플로로글루시놀, 플로로탄닌 또는 갈조류 추출물을 포함하는 가바 ａ형-벤조다이아제핀 수용체 활성용 조성물 및 불안 완화, 경련 개선, 진정 작용, 및 수면 유도 및 개선용 조성물

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104372055A (zh) * 2014-10-16 2015-02-25 青岛博之源生物技术有限公司 一种利用热榨花生粕制备发酵专用花生蛋白的方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015091780A (ja) * 2013-09-30 2015-05-14 御木本製薬株式会社 ヒアルロニダーゼ阻害剤
KR101899546B1 (ko) * 2017-05-11 2018-09-17 한국식품연구원 플로로글루시놀을 유효성분으로 하는 수면 장애 개선, 예방 또는 치료용 조성물, 또는 gaba a 수용체 효능제의 내성 억제 또는 부작용 경감용 조성물
GB2579600B (en) * 2018-12-05 2023-07-05 Byotrol Plc Anti-viral composition

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104372055A (zh) * 2014-10-16 2015-02-25 青岛博之源生物技术有限公司 一种利用热榨花生粕制备发酵专用花生蛋白的方法

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