WO2011115420A3 - Mimétique de matrice extracellulaire adhésive - Google Patents

Mimétique de matrice extracellulaire adhésive Download PDF

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Publication number
WO2011115420A3
WO2011115420A3 PCT/KR2011/001831 KR2011001831W WO2011115420A3 WO 2011115420 A3 WO2011115420 A3 WO 2011115420A3 KR 2011001831 W KR2011001831 W KR 2011001831W WO 2011115420 A3 WO2011115420 A3 WO 2011115420A3
Authority
WO
WIPO (PCT)
Prior art keywords
matrix
extracellular matrix
vitro
vivo
adhesive
Prior art date
Application number
PCT/KR2011/001831
Other languages
English (en)
Other versions
WO2011115420A2 (fr
Inventor
Jaeyoon Kim
Taehoon G. Lee
Kilwon Cho
Hosun Lim
Seung Goo Lee
Original Assignee
Kollodis Biosciences, Inc.
Kollodis Korea, Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kollodis Biosciences, Inc., Kollodis Korea, Co., Ltd. filed Critical Kollodis Biosciences, Inc.
Publication of WO2011115420A2 publication Critical patent/WO2011115420A2/fr
Publication of WO2011115420A3 publication Critical patent/WO2011115420A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Dispersion Chemistry (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne un mimétique de matrice extracellulaire comprenant un hydrogel obtenu par réticulation d'une protéine adhésive recombinante de moule et d'un biopolymère. Ladite matrice d'hydrogel tridimensionnelle constitue un microenvironnement biochimique et biophysique similaire à une matrice extracellulaire native et se révèle donc capable de favoriser une pénétration cellulaire in vivo ou in vitro. La matrice peut être conçue de façon à comporter, en outre, un ou plusieurs peptides bioactifs. Des cellules, capables de proliférer ou de se différencier suite à la mise en place de la matrice in vivo ou in vitro, peuvent également être encapsulées et dispersées dans ladite matrice. L'invention concerne également des procédés de préparation de ladite matrice extracellulaire adhésive et l'utilisation de cette matrice in vivo ou in vitro dans le cadre de l'ingénierie tissulaire ou de l'administration de médicaments.
PCT/KR2011/001831 2010-03-16 2011-03-16 Mimétique de matrice extracellulaire adhésive WO2011115420A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34033810P 2010-03-16 2010-03-16
US61/340,338 2010-03-16

Publications (2)

Publication Number Publication Date
WO2011115420A2 WO2011115420A2 (fr) 2011-09-22
WO2011115420A3 true WO2011115420A3 (fr) 2012-01-26

Family

ID=44649720

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/001831 WO2011115420A2 (fr) 2010-03-16 2011-03-16 Mimétique de matrice extracellulaire adhésive

Country Status (1)

Country Link
WO (1) WO2011115420A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101311325B1 (ko) * 2012-09-13 2013-09-30 이상재 합성 디자인된 3차원 미세환경 구조물
JP5992529B2 (ja) * 2012-09-26 2016-09-14 富士フイルム株式会社 ポリペプチド、足場組成物、軟骨組織修復用組成物、軟骨細胞培養用組成物及びグリコサミノグリカン産生促進用組成物
EP3080246A4 (fr) * 2013-12-11 2017-05-24 The Regents of The University of California Compositions et procédés pour produire et gérer des adipocytes bruns
CN104623725B (zh) * 2014-12-31 2017-01-18 深圳清华大学研究院 生物粘合剂及其制备方法
KR101714695B1 (ko) * 2015-05-18 2017-03-09 한국과학기술연구원 가교화된 pva-ecm 복합체를 제조하는 방법 및 그에 의하여 제조된 pva-ecm 복합체
KR20170017499A (ko) * 2015-08-07 2017-02-15 콜로디스 바이오사이언스, 인코포레이티드 계면활성 접착제
US11578106B2 (en) 2015-08-07 2023-02-14 TME Therapeutics Co., Ltd. Surfactant adhesive composition
CN105457085B (zh) * 2016-01-25 2018-03-02 华中农业大学 一种胶原基贻贝仿生黏附性水凝胶及其制备方法
WO2018030569A1 (fr) * 2016-08-12 2018-02-15 소망화장품주식회사 Composition cosmétique de type maquillage contenant des protéines d'adhérence issues de la moule
AU2016431869B2 (en) * 2016-12-07 2021-12-09 Amolifescience Co., Ltd. Three-dimensional micro-environment structure for controlling cell behavior, three-dimensional surface for controlling cell behavior, and method for manufacturing array and three-dimensional micro-environment structure
CN111727234A (zh) * 2017-11-22 2020-09-29 新泽西州立罗格斯大学 用于细胞扩增的生物活性3d包封培养系统
KR101870104B1 (ko) * 2018-02-28 2018-06-21 주식회사 코스모코스 홍합 접착단백질을 함유하는 모발용 화장료 조성물
KR102222704B1 (ko) * 2018-05-18 2021-03-04 포항공과대학교 산학협력단 하이드로겔 제형 기반의 마이크로니들 접착 패치
CN109568649A (zh) * 2018-11-27 2019-04-05 普丽妍（南京）医疗科技有限公司 一种抗菌止痒温敏复合水凝胶及其制备方法
CN109646723B (zh) * 2019-02-02 2020-05-22 上海瑞凝生物科技有限公司 具有辐射防护作用的医用水凝胶
CN110790885B (zh) * 2019-08-30 2022-05-03 武汉理工大学 一种聚乙烯醇/壳聚糖季铵盐抗菌自愈水凝胶及其制备方法和应用
US11643574B2 (en) 2021-05-28 2023-05-09 Cohesys Inc. Adhesive devices and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040208845A1 (en) * 2003-04-15 2004-10-21 Michal Eugene T. Methods and compositions to treat myocardial conditions
EP1493404A1 (fr) * 2003-06-30 2005-01-05 DePuy Mitek, Inc. Matrice d'échafaudage pour la réparation de tissue conjonctif

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040208845A1 (en) * 2003-04-15 2004-10-21 Michal Eugene T. Methods and compositions to treat myocardial conditions
EP1493404A1 (fr) * 2003-06-30 2005-01-05 DePuy Mitek, Inc. Matrice d'échafaudage pour la réparation de tissue conjonctif

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CANDAN TAMERLER ET AL., ACNANO, vol. 3, no. 7, 2009, pages 1606 - 1615 *
KAZUHIRO NAKANISHI ET AL., J. OF BIOSCIENCE AND BIOENGINEERING, vol. 91, no. 3, 2001, pages 233 - 244 *
KUEN YONG LEE ET AL., CHEMICAL REVIEWS, vol. 101, no. 7, 2001, pages 1869 - 1879 *
LORENZO MORONI ET AL., MATERIALSTODAY, vol. 11, no. 5, 2008, pages 44 - 51 *
YOSHINORI ONUKI ET AL., JOURNAL OF DIABETES SCIENCE AND TECHNOLOGY, vol. 2, no. 6, 2008, pages 1003 - 1015 *

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