WO2011114347A2 - Effet synergique d'un composé naturel utilisé en tant que fongicide et bactéricide pour les cultures agricoles plus spécialement les cultures de cumin - Google Patents

Effet synergique d'un composé naturel utilisé en tant que fongicide et bactéricide pour les cultures agricoles plus spécialement les cultures de cumin Download PDF

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Publication number
WO2011114347A2
WO2011114347A2 PCT/IN2010/000657 IN2010000657W WO2011114347A2 WO 2011114347 A2 WO2011114347 A2 WO 2011114347A2 IN 2010000657 W IN2010000657 W IN 2010000657W WO 2011114347 A2 WO2011114347 A2 WO 2011114347A2
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WO
WIPO (PCT)
Prior art keywords
compound
crop
cumin
cinnamaldehyde
netural
Prior art date
Application number
PCT/IN2010/000657
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English (en)
Other versions
WO2011114347A3 (fr
Inventor
Chetan Balar
Anil Nakum
Original Assignee
Chetan Balar
Anil Nakum
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chetan Balar, Anil Nakum filed Critical Chetan Balar
Publication of WO2011114347A2 publication Critical patent/WO2011114347A2/fr
Publication of WO2011114347A3 publication Critical patent/WO2011114347A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
    • A01N35/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aliphatically bound aldehyde or keto groups, or thio analogues thereof; Derivatives thereof, e.g. acetals

Definitions

  • This invention is based on efficient bactericide and fungicide for agriculture crop especially cumin crop.
  • composition contains a fundamental active ingredient consisting of the association of thymol, eugenol and cinnamaldehyde, a secondary active ingredient consisting of the association of cuminaldehyde, geraniol, vanillin, borneol, menthol, anethole, terpineol, limonene and different glycosides contained in the essences of mustard and jasmine, a surface-active selected among the different families accepted as emulsifying food additives and an oligosaccharide selected among the mano-oligosaccharides, fructo-oligosaccharides, phyco-oligosaccharides proceeding from algae extracts or vegetable tissue.
  • the composition that has just been described is applied to fruit and vegetables in a diluted bath or in solid form incorporated into the waxes that are usually used in post- harvest treatments
  • Embodiments of the present invention provide compositions for controlling a target pest including a pest control product and at least one active agent, wherein: the active agent can be capable of interacting with a receptor in the target pest; the pest control product can have a first activity against the target pest when applied without the active agent and the compositions can have a second activity against the target pest; and the second activity can be greater than the first activity.
  • Pest control compositions, blends, and formulations contain, in a synergistic combinations, at least two ingredients such as Lilac Flower Oil, D- Limonene, Thyme Oil, Lime Oil, Black Seed Oil, Wintergreen Oil, Linalool, Tetrahydrolinalool, Vanillin, Isopropyl myristate, Piperonal (aldehyde), Geraniol, Geraniol 60, Triethyl Citrate, and Methyl Salicylate.
  • Embodiments of the invention relate to a composition for controlling a target pest, wherein the composition includes at least two active ingredients selected from the group consisting of thymyl acetate, linalyl acetate, amyl butyrate, anise star oil, black seed oil, p-cymene, geraniol, isopropyl myristate, d- limonene, linalool, lilac flower oil, methyl salicylate, alpha-pinene, piperonal, piperonyl alcohol, tetrahydrolinalool, thyme oil white, thyme oil red, thymol, vanillin, and wintergreen oil, wherein the composition causes synergistic control of the target pest.
  • the composition causes synergistic control of the target pest.
  • compositions, methods and cell lines related to controlling insects In the existing system as given in US 7541155 (granted patent) wherein the present invention comprises compositions, methods and cell lines related to controlling insects.
  • An embodiment of a composition comprises a plant essential oil and targets at least one receptor of insects chosen from tyramine receptor, Or83b olfactory receptor, and Or43a olfactory receptor, resulting in a change in the intracellular levels of cAMP, Ca2+, or both in the insects.
  • the disclosure provides oral compositions having at least two botanical active ingredients derived from plants.
  • the oral composition also includes an orally acceptable vehicle to deliver an effective amount of the at least two active ingredients in vivo.
  • the botanical active ingredients provide particularly efficacious antimicrobial (antibacterial, antiviral, and/or antifungal), antioxidant, antiinflammatory, anti-ageing, and or healing properties to the oral compositions.
  • JP63255203 A wherein PURPOSE: To protect agricultural crops from vermin, etc., by scattering a composition having stable activity durable over a long period, free from damage against human body and environment and produced by compounding cinnamaldehyde which is nontoxic and harmless to living body with an antioxidant and optionally an emulsifier or supporting the above components on a carrier.
  • CONSTITUTION The objective composition is an emulsifiable concentrate produced by combining cinnamaldehyde with 0.2- lwt % of an antioxidant (e.g. vitamin E, n-propyl gallate, BHT and eugenol.
  • an antioxidant e.g. vitamin E, n-propyl gallate, BHT and eugenol.
  • vitamin E has high antioxidant effect.
  • an emulsifier e.g. fatty acid salt and polyoxyethylene alkyl ether
  • the agent has strong bacteriostatic effect against harmful bacteria in soil, is uninfluential to useful microorganisms, inhibits harmful root-knot nematode and exhibits proliferation promoting effect to harmless nematodes.
  • Agricultural crops can be protected by the use of the composition.
  • the main object of the invention is to introduce the various formulations of compound Cinnamaldehyde and eugenol which are derived from plants as an effective fungicide and bactrricide for plants and also for protecting the crop against various pathogens, with special application to the cumin crop.
  • the compounds cinnamaldehyde and eugenol when used synergistically not only prevents the crop against various diseases but is also helpful for the cumin crop growth and development.
  • the compounds are totally harmless to the crop and the user, eco friendly, cost effective and easily available as compare to other products.
  • the existing products for fungicides and bactericide are synthetic chemicals or antibiotic which are toxic for human health, but cinnamaldehyde and eugenol are organic compound which are naturally available compounds extracted from the plants.
  • This invention is based on efficient treatment and prevention of agriculture crop disease by the use of various formulations of cinnamaldehyde and eugenol.
  • the formulations are effective in prevention arid treatment of various diseases caused by bacteria as well as fungi and as a protection against various plant pathogens.
  • the combination of cinnamaldehyde and eugenol is helpful for the killing of plant pathogenic fungal and bacterial organisms like fuserium sp. Alterneria sp. Pseudomonas sp. thereof and prevention against the same.
  • This invention is based on agricultural use of various formulations of naturally derived compound cinnamaldehyde and eugenol as a fungicide, bactericide and as a protection against various pathogens.
  • the above mentioned formulations are applicable as a protection to a wide variety of plants including vegetable plants, spices plants, flower and gardening plants with special application to the cumin crop. It is in particular very effective in the killing and prevention of plant pathogenic fungal and bacterial organisms like fuserium sp. Alterneria sp. Pseudomonas sp. thereof.
  • Cinnamaldehyde and Eugenol both is efficient compound for treatment of agriculture crop plants. Especially cumin plant.
  • Cinnamaldehyde and Eugenol -Cinnamaldehyde has been proven effective on over 40 different crops, cinnamaldehyde is typically applied to the root systems of plants. Its low toxicity and well- known properties make it ideal for agriculture. Cinnamaldehyde is an effective insecticide also, and its scent is also known to repel animals like cats and dogs. It is especially effective against bacteria, reducing anaerobic bacteria populations. Cinnamaldehyde is used in agriculture because of its low toxicity. It's slightly soluble in water and soluble in organic solvents.Eugenol is hepatotoxic compound also.
  • the combined effects of using cinnamaldehyde with eugenol provide the strongest synergy against fungi and bacteria.
  • the synergy is due to the interference of fungal and bacterial cell wall synthesis and cell wall destruction plus radical scavenging effect.
  • Cinnamaldehyde which is extracted from cinnamon plant part wood as well as leaf is effective against fungus Fusarium sp., Alterneriya sp., Aspergillus sp., fungal sp. and in particular effective for protection of the cumin crop. It acts by killing the sporulation as well as the fungal hyphie on the said crop.
  • the active compound eugenol which is extracted from clove bud or rose petals has bactericidal activity against some of plant pathogenic bacteria like pseudomonas sp., Xenthomonas sp. and is excellent for protection of cumin crop. The two compounds provide a synergistic protection against bacteria and fungi along with several pathogens.
  • the compound with most broad spectrum and toxic to pathogenic fungi of cumin crop was cinnamaldehyde at (0.1 ⁇ g/cm2) followed by cinnamaldehyde acetate (1.00 ⁇ g/cm2), benzaldehyde (1.25 ⁇ g/cm2), 3-phenylpropionaldehyde (2.00 g/cm2), cinnamyl alcohol (2.25 ⁇ g/cm2), salicylaldehyde (2.80 ⁇ / ⁇ 2), and (E)-2-hydroxycinnamic acid (3.50 ⁇ g/cm2). These compounds were more potent than benzaldehyde (10.00 ⁇ g/cm2) and Hexaconazole ( 15.00 ⁇ g/cm2).
  • Mode of action of both the compound cinnamaldehyde and eugenol by foliar spraying prevents or protects the cumin crop by stopping pathogenic organism attack and by killing or static action to fungal and bacteria organism respectively.

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La présente invention est basée sur les effets synergiques d'un composé naturel utilisé en tant que fongicide et bactéricide pour les cultures agricoles plus spécialement les cultures de cumin. L'activité fongicide du cinnamaldéhyde qui est extrait de l'écorce de cannelle ainsi que des feuilles est efficace contre fungus Fusarium sp., Alterneriya sp., Aspergillus sp., principalement les cultures infectées par fungal sp. qui neutralise la sporulation ainsi que l'hyphe fongique sur la culture, et le composé actif eugénol extrait du clou de girofle ou du pétale de rose présente une activité bactéricide contre certaines espèces de bactéries pathogènes des plantes comme pseudomonas sp., Xenthomonas sp., activité bactéricide excellente sur les cultures de cumin. Le composé cinnamaldéhyde examiné est utilisé dans des procédés d'application par contact direct et de fumigation, et comparé avec le benzaldéhyde et l'hexaconazole alors que le composé eugénol est comparé à la straptocycline antibiotique et à l'oxychlorure de cuivre. Sur la base de valeurs LD50 sur 24h, le composé ayant la toxicité à plus large spectre pour les champignons pathogènes des cultures de cumin est le cinnamaldéhyde à (0,1 μg/cm2) suivi par l'acétate de cinnamaldéhyde (1,00 μg/cm2), le benzaldéhyde (1,25 μg/cm2), le 3- phénylpropionaldéhyde (2,00 μg/cm2), l'alcool cinnamylique (2,25 μg/cm2), le salicylaldéhyde (2,80 μg/cm2), et l'acide (E)-2-hydroxycinnamique (3,50 μg/cm2). Ces composés sont plus puissants que le benzaldéhyde (10,00 μg/cm2) et que l'hexaconazole (15,00 μg/cm2), alors que sur la base des valeurs LD50 à 24h, le composé le plus toxique contre les bactéries pathogènes des plantes est l'eugénol à (0,5 μg/cm2) suivi par la straptocycline (2,5 μg/cm2) et l'oxychlorure de cuivre (50,00 μg/cm2). Le mode d'action des deux composés protège les récoltes de cumin par élimination des organismes pathogènes ou repose sur une action statique à l'égard des champignons et des bactéries par pulvérisation respectivement de cinnamaldéhyde et d'eugénol, sur les feuilles de ladite culture.
PCT/IN2010/000657 2010-03-18 2010-10-05 Effet synergique d'un composé naturel utilisé en tant que fongicide et bactéricide pour les cultures agricoles plus spécialement les cultures de cumin WO2011114347A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN711/MUM/2010 2010-03-18
IN711MU2010 2010-03-18

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WO2011114347A2 true WO2011114347A2 (fr) 2011-09-22
WO2011114347A3 WO2011114347A3 (fr) 2011-11-10

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014165969A1 (fr) * 2013-04-12 2014-10-16 Perry Lidster Mélanges antimicrobiens d'une substance bactéricide dérivée d'huile essentielle et d'un fongicide dérive d'huile essentielle rallongeant la durée de conservation des denrées agricoles périssables.
CN110283773A (zh) * 2019-06-25 2019-09-27 云南农业大学 一种饥饿诱导镰刀菌产生分生孢子的方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63255203A (ja) 1987-04-13 1988-10-21 Kiyoshi Saotome 無毒の組成物による農作物の保護方法
WO2009038599A1 (fr) 2007-03-22 2009-03-26 Tyratech, Inc. Compositions synergiques pour la lutte contre les animaux nuisibles
US20090099135A1 (en) 2007-01-16 2009-04-16 Tyratech, Inc. Pest control compositions and methods
US7541155B2 (en) 2003-04-24 2009-06-02 Tyratech, Inc. Methods of screening compositions for potential insect control activity
WO2009117623A2 (fr) 2008-03-19 2009-09-24 Tyratech, Inc. Lutte contre les ravageurs avec des mélanges d'agents de lutte contre les ravageurs naturels

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06239715A (ja) * 1993-02-15 1994-08-30 Biotech Kk 有害微生物の増殖抑制組成物
TWI361044B (en) * 2006-12-04 2012-04-01 Univ Nat Taiwan Antifungal compositions for inhibiting growth of wood decay fungi and use thereof
ES2328322A1 (es) * 2007-10-08 2009-11-11 Timac Agro España, S.A. Composiciones de origen natural para tratar fisiopatias y enfermedades producidas por agentes patogenos de frutas y hortalizas, despues de su cosecha, y metodo para su aplicacion.
US7956092B2 (en) * 2008-04-11 2011-06-07 Alberta Innovates—Technology Futures Non-toxic insecticide

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63255203A (ja) 1987-04-13 1988-10-21 Kiyoshi Saotome 無毒の組成物による農作物の保護方法
US7541155B2 (en) 2003-04-24 2009-06-02 Tyratech, Inc. Methods of screening compositions for potential insect control activity
US20090099135A1 (en) 2007-01-16 2009-04-16 Tyratech, Inc. Pest control compositions and methods
WO2009038599A1 (fr) 2007-03-22 2009-03-26 Tyratech, Inc. Compositions synergiques pour la lutte contre les animaux nuisibles
WO2009117623A2 (fr) 2008-03-19 2009-09-24 Tyratech, Inc. Lutte contre les ravageurs avec des mélanges d'agents de lutte contre les ravageurs naturels

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014165969A1 (fr) * 2013-04-12 2014-10-16 Perry Lidster Mélanges antimicrobiens d'une substance bactéricide dérivée d'huile essentielle et d'un fongicide dérive d'huile essentielle rallongeant la durée de conservation des denrées agricoles périssables.
US11576377B2 (en) 2013-04-12 2023-02-14 Verséa Holdings Inc. Antimicrobial mixtures of an essential oil derived bactericide and an essential oil derived fungicide which extend the shelf-life of perishable agricultural commodities
CN110283773A (zh) * 2019-06-25 2019-09-27 云南农业大学 一种饥饿诱导镰刀菌产生分生孢子的方法

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