WO2011105736A3 - 표면 개질된 산화탄탈륨 나노입자, 이의 제조 방법, 이를 이용한 ｘ-선 컴퓨터 단층촬영용 조영제 및 고유전 박막 - Google Patents

표면 개질된 산화탄탈륨 나노입자, 이의 제조 방법, 이를 이용한 ｘ-선 컴퓨터 단층촬영용 조영제 및 고유전 박막 Download PDF

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Publication number
WO2011105736A3
WO2011105736A3 PCT/KR2011/001165 KR2011001165W WO2011105736A3 WO 2011105736 A3 WO2011105736 A3 WO 2011105736A3 KR 2011001165 W KR2011001165 W KR 2011001165W WO 2011105736 A3 WO2011105736 A3 WO 2011105736A3
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Prior art keywords
oxide nanoparticles
tantalum oxide
same
thin film
preparation
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PCT/KR2011/001165
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English (en)
French (fr)
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WO2011105736A2 (ko
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현택환
오명환
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서울대학교 산학협력단
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Priority to US13/580,594 priority Critical patent/US8871310B2/en
Priority to JP2012554922A priority patent/JP2013520491A/ja
Priority to KR1020127024463A priority patent/KR101879572B1/ko
Priority to EP11747626A priority patent/EP2540282A2/en
Priority to CN2011800106316A priority patent/CN102905696A/zh
Publication of WO2011105736A2 publication Critical patent/WO2011105736A2/ko
Publication of WO2011105736A3 publication Critical patent/WO2011105736A3/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A61K49/0414—Particles, beads, capsules or spheres
    • A61K49/0423—Nanoparticles, nanobeads, nanospheres, nanocapsules, i.e. having a size or diameter smaller than 1 micrometer
    • A61K49/0428—Surface-modified nanoparticles, e.g. immuno-nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N23/00—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
    • G01N23/02—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material
    • G01N23/04—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material and forming images of the material
    • G01N23/046—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material and forming images of the material using tomography, e.g. computed tomography [CT]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2223/00—Investigating materials by wave or particle radiation
    • G01N2223/40—Imaging
    • G01N2223/419—Imaging computed tomograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2223/00—Investigating materials by wave or particle radiation
    • G01N2223/60—Specific applications or type of materials
    • G01N2223/612—Specific applications or type of materials biological material

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Theoretical Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Pulmonology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biochemistry (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

본 발명은 표면 개질된 산화탄탈륨 나노입자, 이의 제조 방법, 이를 이용한 Ｘ-선 컴퓨터 단층촬영용 조영제 및 고유전 박막에 관한 것이다. 보다 상세하게는 본 발명은 표면 개질된 산화탄탈륨 나노입자, 그리고 (i) 계면활성제를 포함하는 유기 용매에 물을 포함하는 수상(aqueous phase)을 첨가하여 유중수 마이크로에멀젼을 제조하는 단계, (ii) 상기 마이크로에멀젼에 탄탈륨 전구체를 도입하는 단계, (iii) 상기 (ii)단계에서 얻은 용액에 유기 실란 그룹 또는 포스핀 그룹을 포함하는 표면 개질제를 첨가하여 반응시키는 단계, (iv) 상기 (iii)단계의 반응결과물로부터 상기 유기 용매를 제거하는 단계, 및 (v) 상기 (iv)단계에서 얻은 혼합물로부터 표면 개질된 산화탄탈륨 나노입자를 분리하는 단계를 포함하는 표면 개질된 산화탄탈륨 나노입자의 제조 방법, 그리고 이를 이용한 X-선 컴퓨터 단층촬영용 조영제 및 고유전 박막에 대한 것이다.
PCT/KR2011/001165 2010-02-23 2011-02-22 표면 개질된 산화탄탈륨 나노입자, 이의 제조 방법, 이를 이용한 ｘ-선 컴퓨터 단층촬영용 조영제 및 고유전 박막 WO2011105736A2 (ko)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US13/580,594 US8871310B2 (en) 2010-02-23 2011-02-22 Surface-modified tantalum oxide nanoparticles, preparation method thereof, and contrast medium for X-ray computed tomography and highly dielectric thin film using same
JP2012554922A JP2013520491A (ja) 2010-02-23 2011-02-22 表面改質された酸化タンタルナノ粒子、その製造方法、それを用いたｘ線コンピュータ断層撮影造影剤及び高誘電薄膜
KR1020127024463A KR101879572B1 (ko) 2010-02-23 2011-02-22 표면 개질된 산화탄탈륨 나노입자, 이의 제조 방법, 이를 이용한 ｘ-선 컴퓨터 단층촬영용 조영제 및 고유전 박막
EP11747626A EP2540282A2 (en) 2010-02-23 2011-02-22 Surface-modified tantalum oxide nanoparticles, preparation method thereof, and contrast medium for x-ray computed tomography and highly dielectric thin film using same
CN2011800106316A CN102905696A (zh) 2010-02-23 2011-02-22 表面改性的氧化钽纳米颗粒及其制备方法、利用该氧化钽纳米颗粒的x射线计算机断层摄影用造影剂及高介电薄膜

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2010-0016365 2010-02-23
KR20100016365 2010-02-23

Publications (2)

Publication Number Publication Date
WO2011105736A2 WO2011105736A2 (ko) 2011-09-01
WO2011105736A3 true WO2011105736A3 (ko) 2012-02-02

Family

ID=44507360

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Application Number Title Priority Date Filing Date
PCT/KR2011/001165 WO2011105736A2 (ko) 2010-02-23 2011-02-22 표면 개질된 산화탄탈륨 나노입자, 이의 제조 방법, 이를 이용한 ｘ-선 컴퓨터 단층촬영용 조영제 및 고유전 박막

Country Status (6)

Country Link
US (1) US8871310B2 (ko)
EP (1) EP2540282A2 (ko)
JP (1) JP2013520491A (ko)
KR (1) KR101879572B1 (ko)
CN (1) CN102905696A (ko)
WO (1) WO2011105736A2 (ko)

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KR101634269B1 (ko) * 2013-12-31 2016-06-30 주식회사 태산솔루젼스 ３ｄ 스캔용 스프레이 코팅 조성물
WO2018070734A1 (ko) * 2016-10-14 2018-04-19 서울대학교산학협력단 코어쉘 구조를 포함하는 조영 효과 및 조직 접착 특성을 가지는 표지물질 및 이의 제조방법
US10354768B2 (en) 2017-01-10 2019-07-16 Hamilton Sunstrand Corporation Radiographic and computed tomography inspection anti-counterfeit security
KR101981740B1 (ko) * 2017-12-20 2019-08-28 한스바이오메드 주식회사 체내 삽입형 미립자 및 이의 제조방법
CN114981988A (zh) 2019-11-27 2022-08-30 立方光伏股份有限公司 钙钛矿半导体器件中的金属氧化物纳米颗粒电子传输层
CN111289592B (zh) * 2020-02-28 2022-07-22 北京农业信息技术研究中心 同时活体检测植物体内多种糖类的微阵列传感器及其制备与应用
CN111281410B (zh) * 2020-03-13 2021-04-13 广东医科大学附属医院 一种基于造影技术的脑血管疾病成像方法及应用的造影剂
KR102477180B1 (ko) 2020-06-04 2022-12-14 서울대학교산학협력단 색전 물질
US20220048788A1 (en) * 2020-08-14 2022-02-17 Board Of Trustees Of Michigan State University Tantalum Oxide Nanoparticle Contrast Agents
KR102596635B1 (ko) 2021-11-09 2023-11-02 한국전자기술연구원 나노입자를 소수성으로 표면 개질하는 방법
KR102665324B1 (ko) * 2022-03-03 2024-05-14 가톨릭대학교 산학협력단 3d 프린트용 복합소재, 이의 제조방법 및 이를 포함하는 3d 프린트 스텐트
CN115177736A (zh) * 2022-07-20 2022-10-14 中国人民解放军陆军军医大学第一附属医院 具有软骨靶向和过氧化氢酶活性的氨基化钽纳米颗粒和制备方法及用途

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Also Published As

Publication number Publication date
JP2013520491A (ja) 2013-06-06
CN102905696A (zh) 2013-01-30
US8871310B2 (en) 2014-10-28
US20130065995A1 (en) 2013-03-14
EP2540282A2 (en) 2013-01-02
WO2011105736A2 (ko) 2011-09-01
KR101879572B1 (ko) 2018-07-19
KR20130037664A (ko) 2013-04-16

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