WO2011093347A1 - 自動分析装置 - Google Patents
自動分析装置 Download PDFInfo
- Publication number
- WO2011093347A1 WO2011093347A1 PCT/JP2011/051516 JP2011051516W WO2011093347A1 WO 2011093347 A1 WO2011093347 A1 WO 2011093347A1 JP 2011051516 W JP2011051516 W JP 2011051516W WO 2011093347 A1 WO2011093347 A1 WO 2011093347A1
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- WIPO (PCT)
- Prior art keywords
- chip
- sample
- capacitance
- tip
- nozzle
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
- G01N2035/1013—Confirming presence of tip
Definitions
- the present invention relates to an automatic analyzer that performs qualitative and quantitative analysis of biological samples such as serum and urine.
- the automatic analyzer analyzes a sample to be measured by adding a reagent or the like to a sample to be measured (for example, a biological sample such as serum or urine) and measuring its physical properties.
- a sample to be measured for example, a biological sample such as serum or urine
- a reaction liquid that is a measurement target sample or a mixed liquid of a measurement target sample and a reagent is sucked using a probe and transported to an analysis unit. It is necessary to prevent the reaction liquid adhering to the liquid from being brought into another suction target (cross-contamination).
- a disposable tip is detachably provided at a portion where the probe is sucked into the suction target, and the tip adhering material is contaminated by contamination of other suction targets by appropriately replacing the tip.
- a technique for suppressing cross contamination is disclosed.
- the tip When using a probe equipped with a detachable tip (so-called disposable tip), the tip may fall off the probe depending on the attached state, in which case the loss of the specimen or reaction solution, There are concerns about the occurrence of contamination of the operator accessible part of the automatic analyzer and the increase of contamination due to continued operation. Therefore, it is important to detect the tip quickly when the tip is dropped, and to stop the operation of the dispensing device to suppress further contamination.
- the present invention has been made in view of the above, and an object of the present invention is to provide an automatic analyzer that can quickly detect chipping from a probe.
- the present invention provides an automatic analyzer for analyzing a measurement target sample, a sample container for storing the measurement target sample, a probe mechanism for dispensing the measurement target sample, Detects electrostatic capacitance between a conductive tip detachably attached to a portion of the probe mechanism immersed in the sample to be measured and a reference potential predetermined for the probe mechanism tip and the automatic analyzer. And a mounting state determination unit that determines a mounting state of the chip on the probe mechanism based on a detection result of the capacitance detection unit.
- FIG. 1 is a diagram schematically showing a part relating to dispensing in the configuration of the automatic analyzer according to the embodiment of the present invention, and showing a state where a tip is mounted on a nozzle of a dispensing mechanism. is there.
- an automatic analyzer 100 includes a sample container 2 that houses a measurement target sample 1 (for example, a biological sample such as serum or urine), and a mixed liquid obtained by mixing the measurement target sample 1 and a reagent. 3, a dispensing probe 5 that dispenses the sample 1 to be measured in the sample container 2 into the reaction container 4, a drive unit 6 that drives the dispensing probe 5 to pivot and move up and down, and a dispensing probe 5 and a control unit 8 that controls the overall operation of the automatic analyzer 100, and a control unit 8 that controls the overall operation of the automatic analyzer 100.
- a measurement target sample 1 for example, a biological sample such as serum or urine
- a mixed liquid obtained by mixing the measurement target sample 1 and a reagent for example, a biological sample such as serum or urine
- a dispensing probe 5 that dispenses the sample 1 to be measured in the sample container 2 into the reaction container 4
- a drive unit 6 that drives the dispensing probe 5 to pivot and move up and down
- the dispensing probe 5 is provided so as to face the opening of the sample container 2 and is provided with a nozzle 10 that is immersed in and sucked into the measurement target sample 1 accommodated in the sample container 2.
- a disposable conductive tip 11 is detachably attached to a portion of the nozzle 10 that is immersed in the measurement target sample 1 at the tip (lower end).
- the dispensing probe 5 sucks the measurement target sample 1, and then the nozzle 10 is driven by the driving unit 6 to a position facing the opening of the reaction container 4 to discharge the measurement target sample 1 into the reaction container 4.
- the tip 11 since only the tip 11 is in contact with the measurement target sample 1, it is possible to suppress the measurement target sample 1 from adhering to the nozzle 10 and to suppress cross contamination.
- the sample container 2 that accommodates the sample 1 to be measured is made of a conductive or non-conductive material, and is disposed in the vicinity of a portion that has a predetermined reference potential 9 in the automatic analyzer 100.
- the reference potential 9 is a ground potential (hereinafter referred to as the ground potential 9)
- the ground potential 9 a ground potential
- the sample container 2 is made conductive and connected to the ground potential 9, or an electrode connected to the ground potential 9 is provided at a position in contact with the measurement target sample 1 inside the sample container 2.
- the accommodated measurement target sample 1 may have a ground potential 9. In that case, the electrostatic capacitance between the nozzle 10 and the measurement target sample 1 becomes the electrostatic capacitance between the nozzle 10 and the ground potential 9, and at the same time, the electrostatic capacitance between the measurement target sample 1 and the ground potential 9 becomes not exist.
- the reaction vessel 4 containing the mixed liquid 3 is made of a conductive or non-conductive material, and is disposed in the vicinity of a portion where the ground potential 9 is obtained. Therefore, when the nozzle 10 and the reaction vessel 4 are opposed to each other, the electrostatic capacity between the nozzle 10 and the mixed liquid 3 and the electrostatic capacity between the mixed liquid 3 and the ground potential 9 are between the nozzle 10 and the ground potential 9. There is generally a capacitance, a capacitance between the nozzle 10 and the ground potential 9.
- the reaction vessel 4 is made conductive and connected to the ground potential 9, or an electrode connected to the ground potential 9 is provided at a position in contact with the mixed solution 3 inside the reaction vessel 4 so that the mixed solution 3 is grounded. A configuration in which the potential is 9 may be adopted. In that case, the electrostatic capacity between the nozzle 10 and the liquid mixture 3 becomes the electrostatic capacity between the nozzle 10 and the ground potential 9, and there is no electrostatic capacity between the liquid mixture 3 and the ground potential 9 at the same time. .
- the electrostatic capacitance detection unit 7 is electrically connected to the ground potential 9 and the nozzle 10, and detects the electrostatic capacitance between the ground potential 9 and the nozzle 10, and converts the detected electrostatic capacitance into a voltage signal. Output to the control unit 8.
- the control unit 8 controls the entire operation of the automatic analyzer 100 such as the drive unit 6 and the capacitance detection unit 7, and is attached to the nozzle 10 based on a voltage signal from the capacitance detection unit 7.
- a liquid level detector 8A that detects the relative positional relationship between the tip (lower end) of the chip 11 and the liquid level of the sample 1 to be measured, and the nozzle 10 of the chip 11 based on a voltage signal from the capacitance detector 7.
- a wearing state determination unit for detecting a mounting state of the head or a mounting state detection unit 8B as a mounting state determination unit.
- the control unit 8 controls the operation of the dispensing probe 5 based on the detection result from the liquid level detection unit 8A, and controls the amount of the tip 11 immersed in the liquid level in the dispensing process described later. Moreover, the control part 8 controls operation
- the mounting state detection unit 8B detects an abnormality in the mounting state of the tip 11 with respect to the nozzle 10
- the operation of the automatic analyzer 100 is stopped, a warning is displayed on a display device (not shown), or a warning sound is generated. Or alert the operator of the abnormality.
- the abnormality in the mounting state of the tip 11 with respect to the nozzle 10 includes an unintentional drop of the tip 11 and an insufficient amount of insertion into the nozzle 10 into the tip 11.
- the control unit 8 controls the operation of each component of the automatic analyzer 100.
- the liquid level detection unit 8A compares the voltage signal from the capacitance detection unit 7 with a preset threshold value, and detects the liquid level position based on the comparison result.
- the mounting state detection unit 8B compares the voltage signal from the capacitance detection unit 7 with a preset threshold value, and detects the mounting state of the nozzle 10 on the chip 11 based on the comparison result.
- the threshold is set for each operation state in the dispensing process (described later), and the threshold for each operation state is selected and used.
- FIGS. 2A to 2D are diagrams showing a dispensing process of the automatic analyzer according to the embodiment of the present invention.
- 2A is a diagram illustrating a chip mounting process
- FIG. 2B is a suction process
- FIG. 2C is a discharge process
- FIG. 2D is a chip discarding process.
- the dispensing probe 5 is driven by the driving unit 6 to move the nozzle 10 not mounted with the chip 11 to the chip mounting position.
- a chip rack 11A is provided at the chip mounting position, and a plurality of unused chips 11 are arranged.
- the tip 11 is formed to be detachable from the nozzle 10, and the tip 11 is attached to the tip of the nozzle 10 by inserting the tip of the nozzle 10 into the tip 11.
- the process proceeds to the next suction step.
- the nozzle 10 with the chip 11 attached is moved to the suction position.
- the suction position is a position where the nozzle 10 of the dispensing probe 5 and the opening of the sample container 2 face each other.
- the dispensing probe 5 is lowered by the drive unit 6, and the nozzle 10 is lowered into the sample container 2.
- the tip (lower end) of the tip 11 attached to the tip of the nozzle 10 stops at the position where the tip (lower end) of the tip 11 is immersed in the sample 1 to be measured, and rises after sucking the sample 1 to be measured.
- the process proceeds to the next discharge step.
- the nozzle 10 equipped with the chip 11 is moved to the discharge position.
- the discharge position is a position where the nozzle 10 of the dispensing probe 5 and the opening of the reaction container 4 face each other.
- the dispensing probe 5 is lowered by the drive unit 6, the nozzle 10 is inserted into the reaction container 4, and the measurement target sample 1 is discharged and then raised.
- the process proceeds to the next chip discarding process.
- the nozzle 10 equipped with the chip 11 is moved to the chip discarding position.
- the tip discarding position is a position where the nozzle 10 of the dispensing probe 5 and the opening of the tip discarding container 12 for discarding the used tip 11 face each other.
- the chip 11 is removed from the nozzle 10 by a chip dropping mechanism (not shown) at the chip discarding position, and the used chip 11 is discarded in the chip discarding container 12.
- the process moves to the suction process for the dispensing process for the next sample to be measured, and the dispensing process is repeated as many times as necessary.
- FIG. 3 shows the capacitance between the nozzle 10 of the dispensing probe 5 and the ground potential 9 of the automatic analyzer 100 according to the embodiment of the present invention, and the output voltage of the voltage signal of the capacitance detector 7.
- the horizontal axis indicates the capacitance between the nozzle 10 and the ground potential 9, and the vertical axis indicates the output voltage.
- the output voltage is V1
- the output voltage decreases as the capacitance decreases.
- the capacitance is C3
- the output voltage becomes V3.
- the capacitance is C2
- the output voltage decreases.
- the voltage is V2.
- the capacitance C3 is the capacitance when the chip 11 is mounted on the nozzle 10
- the capacitance C2 is the capacitance when the chip 11 is not mounted on the nozzle 10, and the capacitance C1. Is a capacitance when the chip 11 is mounted on the nozzle 10 and immersed in the sample 1 to be measured.
- FIG. 4 is a diagram showing an example of changes in capacitance at each time of the dispensing process.
- the vertical axis indicates the voltage signal from the capacitance detection unit 7, and the horizontal axis indicates the time in the dispensing process.
- the output voltage of the voltage signal output from the capacitance detection unit 7 to the control unit 8 is set so as to change in accordance with the relationship as shown in FIG.
- Time t1 to t2 corresponds to the chip mounting process shown in FIG. 2A.
- the capacitance detector 7 outputs a voltage signal e (output voltage V2: see FIG. 3).
- the electrostatic capacity does not substantially change during the time t1 to t2 when the dispensing probe 5 is driven by the driving unit 6 to move the nozzle 10 without the tip 11 to the tip mounting position, and the voltage signal e is output.
- the capacitance changes to C3 when the tip 11 is normally attached to the nozzle 10, and the voltage signal c (output voltage V3: see FIG. 3) is output.
- the threshold value set in the wearing state detection unit 8B is set to a value (for example, voltage signal d) between the voltage signal c in the wearing state and the voltage signal e in the non-wearing state.
- Time t2 to t6 corresponds to the suction process shown in FIG. 2B. From time t2 to t3, the nozzle 10 equipped with the chip 11 is moved to the suction position, but the capacitance is not substantially changed, and the capacitance detector 7 outputs the voltage signal c.
- the threshold value set in the wearing state detection unit 8B is set to a value (for example, voltage signal d) between the voltage signal c in the wearing state and the voltage signal e in the non-wearing state.
- the output voltage from the capacitance detection unit 7 is larger than the threshold value d, it is moved normally.
- the output voltage is smaller than the threshold value, it is determined that an abnormality such as the chip 11 dropping from the nozzle 10 has occurred.
- the dispensing probe 5 is lowered, and the nozzle 10 is lowered into the sample container 2.
- the capacitance changes to C1, and the voltage signal a (output voltage V1: FIG. 3) is output.
- the threshold value set in the liquid level detection unit 8B is set to a value (for example, the voltage signal b) between the voltage signal c and the voltage signal a in a state where the chip 11 is immersed.
- the output voltage from the capacitance detection unit 7 becomes larger than the threshold value b, it is determined that the tip of the chip 11 is immersed in the liquid surface of the measurement target sample 1.
- the lowering of the dispensing probe 5 is stopped.
- the capacitance is changed again to C3, and the voltage signal c is output.
- the electrostatic capacity becomes unstable during the suction of the measurement target sample 1 by the dispensing probe 5 (indicated by a dotted line in FIG. 4), so that the liquid level detection unit 8A and the mounting state detection unit 8B perform the detection operation. Do not do.
- Times t6 to t8 correspond to the discharge process shown in FIG. 2C.
- the nozzle 10 equipped with the chip 11 is moved to the ejection position, but the capacitance is not substantially changed, and the capacitance detector 7 outputs the voltage signal c.
- the threshold value set in the wearing state detection unit 8B is set to a value (for example, voltage signal d) between the voltage signal c in the wearing state and the voltage signal e in the non-wearing state.
- the measurement target sample 1 is discharged from the nozzle 10 of the dispensing probe 5 to the reaction container 4 at time t7 to t8.
- the liquid level detection unit 8A and the mounting state detection unit 8B perform the detection operation. Not performed.
- Times t8 to t9 correspond to the chip discarding process shown in FIG. 2D.
- the nozzle 10 to which the chip 11 is attached is moved to the chip discarding position, but the capacitance is not substantially changed, and the capacitance detection unit 7 outputs the voltage signal c.
- the threshold value set in the wearing state detection unit 8B is set to a value (for example, voltage signal d) between the voltage signal c in the wearing state and the voltage signal e in the non-wearing state.
- the threshold value set in the wearing state detection unit 8B is set to a value (for example, voltage signal d) between the voltage signal c in the wearing state and the voltage signal e in the non-wearing state.
- the driving probe 6 drives the dispensing probe 5 to move the nozzle 10 not mounted with the tip 11 to the tip mounting position.
- a chip rack 11A is provided at the chip mounting position, and a plurality of unused chips 11 are arranged.
- the tip 11 is formed to be detachable from the nozzle 10, and the tip 11 is attached to the tip of the nozzle 10 by inserting the tip of the nozzle 10 into the tip 11. When the tip 11 is normally mounted on the nozzle 10, the nozzle 10 is moved to the suction position.
- the dispensing probe 5 is lowered by the drive unit 6 at the suction position, and the nozzle 10 is lowered into the sample container 2.
- the tip (lower end) of the tip 11 attached to the tip of the nozzle 10 stops at the position where the tip (lower end) of the tip 11 is immersed in the sample 1 to be measured, and rises after sucking the sample 1 to be measured.
- the discharge position is a position where the nozzle 10 of the dispensing probe 5 and the opening of the reaction container 4 face each other.
- the dispensing probe 5 is lowered by the drive unit 6, the nozzle 10 is inserted into the reaction container 4, and the measurement target sample 1 is discharged and then raised.
- the nozzle 10 to which the chip 11 is attached is moved to the chip discarding position.
- the tip discarding position is a position where the nozzle 10 of the dispensing probe 5 and the opening of the tip disposal container 12 for discarding the used tip 11 face each other.
- the chip 11 is removed from the nozzle 10 by a chip dropping mechanism (not shown) at the chip discarding position, and the used chip 11 is discarded in the chip discarding container 12.
- the tip When using a probe with a disposable tip (disposable tip) that is detachable, the tip may fall off from the probe. In this case, loss of sample, loss of dispensed reaction solution, operator contact Contamination of possible parts may occur, and there is a risk of contamination spreading due to the operation of the automatic analyzer. Therefore, it is important that when the tip is dropped, it is detected and the operation of the dispensing device is stopped to further prevent the spread of contamination.
- chip dropout there is no mention of dealing with chip dropout, and it is confirmed using, for example, an optical sensor as a means of detecting whether the disposable chip is normally attached to the probe. However, if the disposable chip has moved to the detection position of the sensor, it cannot be confirmed, and the operation of the device cannot be stopped immediately after a mounting abnormality such as chip removal occurs. It is not possible to suppress the expansion of defects.
- the conductive portion is immersed in the measurement target sample 1 accommodated in the sample container 2 of the nozzle 10 of the dispensing probe 5 that is conveyed by sucking and discharging the measurement target sample.
- the chip 11 is detachably mounted, and the mounting state of the chip 11 to the dispensing probe 5 is detected based on the detection result of the capacitance detection unit 7 that detects the capacitance between the chip 11 and the ground potential. Since it comprised so that it can always confirm that the chip
- the ground potential 9 is used as the predetermined reference potential
- the present invention is not limited to this, and a potential other than the predetermined ground potential is set to the reference potential 9 in the analyzer. It may be used as Even in this case, the same effect as the present embodiment can be obtained.
- sample container 2 and the reaction container 4 are made of a conductive material and connected to the ground potential 9 as a reference potential.
- the present invention is not limited to this, and the sample container 2 and the reaction container 4
- the material may be made of a material that does not take into account conductivity, and may have a potential other than the reference potential (ground potential 9). In this case, the capacitance between the sample container 2 or the reaction container 4 and the reference potential 9 is considered in advance.
- the configuration is such that the mounting state of the chip 11 to the nozzle 10 is detected based on the comparison result between the detection result from the capacitance detection unit 7 and the threshold value.
- the present invention is not limited to this, and the mounting state of the chip 11 to the nozzle 10 may be detected depending on whether the change rate of the detection result is within a predetermined range.
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Abstract
Description
2 試料容器
3 混合液
4 反応容器
5 分注プローブ
6 駆動部
7 静電容量検出部
8 制御部
8A 液面検出部
8B 装着状態判定部
9 接地電位(基準電位)
10 ノズル
11 チップ
11A チップラック
12 チップ破棄容器
100 自動分析装置
Claims (5)
- 測定対象試料の分析を行う自動分析装置であって、
前記測定対象試料を収容する試料容器と、
前記測定対象試料を分注するプローブ機構と、
前記プローブ機構の前記測定対象試料との浸漬部分に着脱可能に装着された導電性のチップと、
前記プローブ機構のチップと前記自動分析装置に予め定められた基準電位との間の静電容量を検出する静電容量検出部と、
前記静電容量検出部の検出結果に基づいて前記チップのプローブ機構への装着状態を判定する装着状態判定部と
を備えたことを特徴とする自動分析装置。 - 請求項1記載の自動分析装置において、
前記試料容器に収容された前記測定対象試料は、前記基準電位に電気的に接続されていることを特徴とする自動分析装置。 - 請求項1記載の自動分析装置において、
前記装着状態判定部は、前記静電容量と予め定めた閾値との比較結果に基づいて、前記チップの着脱状態を判断することを特徴とする自動分析装置。 - 請求項1記載の自動分析装置において、
前記装着状態判定部は、前記静電容量の変化率に基づいて、前記チップの着脱状態を判断することを特徴とする自動分析装置。 - 前記測定対象試料を収容する試料容器と、前記測定対象試料を分注するプローブ機構と、前記プローブ機構の前記測定対象試料との浸漬部分に着脱可能に装着された導電性のチップとを備えた自動分析装置における分析方法であって、前記プローブ機構のチップと前記自動分析装置に予め定められた基準電位との間の静電容量を検出する手順と、前記静電容量検出部の検出結果に基づいて前記チップのプローブ機構への装着状態を判定する手順とを備えたことを特徴とする分析方法。
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11737060A EP2530473A1 (en) | 2010-01-29 | 2011-01-26 | Automatic analyzing device |
CN201180007538XA CN102725642A (zh) | 2010-01-29 | 2011-01-26 | 自动分析装置 |
JP2011551883A JPWO2011093347A1 (ja) | 2010-01-29 | 2011-01-26 | 自動分析装置 |
US13/520,263 US20120309099A1 (en) | 2010-01-29 | 2011-01-26 | Automatic analyzing device |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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JP2010018089 | 2010-01-29 | ||
JP2010-018089 | 2010-01-29 |
Publications (1)
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WO2011093347A1 true WO2011093347A1 (ja) | 2011-08-04 |
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Application Number | Title | Priority Date | Filing Date |
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PCT/JP2011/051516 WO2011093347A1 (ja) | 2010-01-29 | 2011-01-26 | 自動分析装置 |
Country Status (5)
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US (1) | US20120309099A1 (ja) |
EP (1) | EP2530473A1 (ja) |
JP (1) | JPWO2011093347A1 (ja) |
CN (1) | CN102725642A (ja) |
WO (1) | WO2011093347A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013044692A (ja) * | 2011-08-26 | 2013-03-04 | Hitachi High-Technologies Corp | 分注機構及びこれを用いた自動分析装置 |
JP2013096910A (ja) * | 2011-11-02 | 2013-05-20 | Tosoh Corp | B/f洗浄装置 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL2011710C2 (en) * | 2013-10-31 | 2015-05-04 | F G J Lammertink Beheer B V | Device for cleaning a stylus of a measuring probe. |
JP6191778B2 (ja) * | 2014-08-20 | 2017-09-06 | 株式会社島津製作所 | 質量分析装置 |
CN106226358B (zh) * | 2016-09-08 | 2023-05-26 | 上海市特种设备监督检验技术研究院 | 一种用于埋地钢管外防腐层的检测器及其检测方法 |
JP6837086B2 (ja) * | 2019-01-24 | 2021-03-03 | 日本電子株式会社 | 自動分析装置 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0829424A (ja) | 1994-07-15 | 1996-02-02 | Hitachi Ltd | 免疫学的分析方法及び装置 |
JPH0835971A (ja) * | 1994-07-25 | 1996-02-06 | Hitachi Ltd | ピペット |
JP2005201769A (ja) * | 2004-01-15 | 2005-07-28 | Sysmex Corp | 分析装置 |
JP2007322394A (ja) * | 2006-06-05 | 2007-12-13 | Olympus Corp | 分注装置および自動分析装置 |
-
2011
- 2011-01-26 EP EP11737060A patent/EP2530473A1/en not_active Withdrawn
- 2011-01-26 WO PCT/JP2011/051516 patent/WO2011093347A1/ja active Application Filing
- 2011-01-26 CN CN201180007538XA patent/CN102725642A/zh active Pending
- 2011-01-26 JP JP2011551883A patent/JPWO2011093347A1/ja active Pending
- 2011-01-26 US US13/520,263 patent/US20120309099A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0829424A (ja) | 1994-07-15 | 1996-02-02 | Hitachi Ltd | 免疫学的分析方法及び装置 |
JPH0835971A (ja) * | 1994-07-25 | 1996-02-06 | Hitachi Ltd | ピペット |
JP2005201769A (ja) * | 2004-01-15 | 2005-07-28 | Sysmex Corp | 分析装置 |
JP2007322394A (ja) * | 2006-06-05 | 2007-12-13 | Olympus Corp | 分注装置および自動分析装置 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013044692A (ja) * | 2011-08-26 | 2013-03-04 | Hitachi High-Technologies Corp | 分注機構及びこれを用いた自動分析装置 |
JP2013096910A (ja) * | 2011-11-02 | 2013-05-20 | Tosoh Corp | B/f洗浄装置 |
Also Published As
Publication number | Publication date |
---|---|
EP2530473A1 (en) | 2012-12-05 |
JPWO2011093347A1 (ja) | 2013-06-06 |
US20120309099A1 (en) | 2012-12-06 |
CN102725642A (zh) | 2012-10-10 |
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