WO2010085039A3 - 노긴―유래 펩타이드 및 그의 용도 - Google Patents

노긴―유래 펩타이드 및 그의 용도 Download PDF

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Publication number
WO2010085039A3
WO2010085039A3 PCT/KR2009/006930 KR2009006930W WO2010085039A3 WO 2010085039 A3 WO2010085039 A3 WO 2010085039A3 KR 2009006930 W KR2009006930 W KR 2009006930W WO 2010085039 A3 WO2010085039 A3 WO 2010085039A3
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WIPO (PCT)
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present
noggin
peptide
preventing
treating
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PCT/KR2009/006930
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English (en)
French (fr)
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WO2010085039A2 (ko
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정용지
김영덕
김은미
송상수
홍일
조경미
김수미
한상민
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(주)케어젠
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Priority to ES09838926.5T priority Critical patent/ES2548982T3/es
Priority to EP09838926.5A priority patent/EP2383283B1/en
Priority to CN200980157908.0A priority patent/CN102348716B/zh
Priority to US13/145,390 priority patent/US8729028B2/en
Priority to JP2011547757A priority patent/JP5492226B2/ja
Publication of WO2010085039A2 publication Critical patent/WO2010085039A2/ko
Publication of WO2010085039A3 publication Critical patent/WO2010085039A3/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)

Abstract

본 발명은 노긴-유래 펩타이드 및 이를 포함하는 발모 촉진용, 피부 상태 개선용, 항염증 또는 골질환 예방 또는 치료용 조성물에 관한 것이다. 본 발명의 노긴(Noggin)-유래 펩타이드는 천연의 인간 노긴과 동일하거나 유사한 기능을 하며 노긴과 비교하여 안정성이 보다 더 우수하며, 피부 투과도가 매우 뛰어나다. 본 발명에 따르면, 본 발명의 펩타이드를 유효성분으로 포함하는 조성물은 성장인자-관련 증후, 즉 탈모, 피부 개선 또는 창상, 성장인자 과발현 증후의 치료, 예방 또는 개선하는 데 매우 우수한 효능을 발휘한다. 따라서 상술한 본 발명의 펩타이드의 우수한 활성 및 안정성은, 의약, 의약외품 및 화장품에 매우 유리하게 적용될 수 있도록 한다.
PCT/KR2009/006930 2009-01-20 2009-11-24 노긴―유래 펩타이드 및 그의 용도 WO2010085039A2 (ko)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES09838926.5T ES2548982T3 (es) 2009-01-20 2009-11-24 Péptido derivado de nogina y uso del mismo
EP09838926.5A EP2383283B1 (en) 2009-01-20 2009-11-24 Noggin-derived peptide and use thereof
CN200980157908.0A CN102348716B (zh) 2009-01-20 2009-11-24 头蛋白-来源的肽及其用途
US13/145,390 US8729028B2 (en) 2009-01-20 2009-11-24 Noggin-derived peptide and use thereof
JP2011547757A JP5492226B2 (ja) 2009-01-20 2009-11-24 ノギン由来のペプチド及びその用途

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2009-0004668 2009-01-20
KR1020090004668A KR101163171B1 (ko) 2009-01-20 2009-01-20 노긴?유래 펩타이드 및 그의 용도

Publications (2)

Publication Number Publication Date
WO2010085039A2 WO2010085039A2 (ko) 2010-07-29
WO2010085039A3 true WO2010085039A3 (ko) 2010-09-16

Family

ID=42356286

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/006930 WO2010085039A2 (ko) 2009-01-20 2009-11-24 노긴―유래 펩타이드 및 그의 용도

Country Status (7)

Country Link
US (1) US8729028B2 (ko)
EP (1) EP2383283B1 (ko)
JP (1) JP5492226B2 (ko)
KR (1) KR101163171B1 (ko)
CN (1) CN102348716B (ko)
ES (1) ES2548982T3 (ko)
WO (1) WO2010085039A2 (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101198918B1 (ko) * 2009-09-01 2012-11-07 (주)케어젠 Ｗｎｔ１０?유래 펩타이드 및 그의 용도
KR101329411B1 (ko) * 2012-05-31 2013-11-14 주식회사 엘지생활건강 피부투과성 펩타이드
KR101578901B1 (ko) 2013-09-11 2015-12-28 (주)셀아이콘랩 발모 촉진 펩타이드, 이의 제조방법, 및, 이를 함유하는 탈모방지 또는 발모촉진용 조성물
KR101600032B1 (ko) * 2013-09-26 2016-03-04 (주)피앤피바이오팜 Ｂｍｐ 활성 억제 기능을 갖는 신규 펩타이드 및 그의 용도
KR101632948B1 (ko) * 2014-05-13 2016-06-27 (주)케어젠 항염증, 골 형성 및 발모 촉진 활성을 갖는 펩타이드 및 이의 용도
KR101610861B1 (ko) * 2014-07-28 2016-04-11 (주)케어젠 골분화 촉진능 및 치주인대섬유모세포 활성 촉진능을 갖는 펩타이드 및 이의 용도
KR101576904B1 (ko) 2014-07-31 2015-12-14 (주)케어젠 파골세포 분화 및 활성 억제능을 갖는 펩타이드 및 이의 용도
KR101772574B1 (ko) * 2015-07-14 2017-08-30 (주)피앤피바이오팜 모낭 세포의 재생과 성장을 촉진하는 성장인자, 고안정성 섬유아세포 성장인자 변이체 및 노긴 펩타이드를 함유한 헤어케어 화장품 조성물
KR101800877B1 (ko) * 2016-02-18 2017-11-27 (주)케어젠 발모 촉진 활성 및 멜라닌 생성 촉진 활성을 나타내는 펩타이드 및 이의 용도
KR101791526B1 (ko) * 2016-02-18 2017-11-01 (주)케어젠 발모 촉진 활성을 나타내는 펩타이드 및 이의 용도
KR101831887B1 (ko) * 2016-03-09 2018-02-27 (주)케어젠 발모 촉진 활성 및 멜라닌 생성 촉진 활성을 나타내는 펩타이드 및 이의 용도
JP6835867B2 (ja) * 2016-03-18 2021-02-24 ケアジェン カンパニー, リミテッドCaregen Co., Ltd. フィナステリドとペプチドの結合体
KR101948238B1 (ko) * 2016-08-19 2019-02-14 (주)케어젠 미녹시딜과 펩타이드의 결합체
CN106727682A (zh) * 2017-01-20 2017-05-31 李玉红 一种用于治疗脱发的制剂
EP3583944A4 (en) * 2017-02-16 2021-03-03 Caregen Co., Ltd. CONJUGATE OF SALICYLIC ACID AND PEPTIDE
KR101951283B1 (ko) * 2017-11-13 2019-02-22 양미경 탈모의 예방 또는 치료용, 또는 발모 또는 육모 촉진용 약학 또는 화장료 조성물
KR102160566B1 (ko) 2019-01-16 2020-09-28 (주)케어젠 미녹시딜과 펩타이드의 결합체
KR102221365B1 (ko) * 2019-05-07 2021-03-02 (주)케어젠 트롤록스-펩타이드 결합체 및 그의 용도

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Publication number Priority date Publication date Assignee Title
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Also Published As

Publication number Publication date
KR101163171B1 (ko) 2012-07-19
US8729028B2 (en) 2014-05-20
WO2010085039A2 (ko) 2010-07-29
ES2548982T3 (es) 2015-10-22
KR20100085407A (ko) 2010-07-29
EP2383283A2 (en) 2011-11-02
EP2383283B1 (en) 2015-07-08
CN102348716B (zh) 2014-07-16
US20110312884A1 (en) 2011-12-22
JP2012515769A (ja) 2012-07-12
CN102348716A (zh) 2012-02-08
JP5492226B2 (ja) 2014-05-14
EP2383283A4 (en) 2012-07-04

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