WO2010041141A3 - Oil-based foamable carriers and formulations - Google Patents

Oil-based foamable carriers and formulations Download PDF

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Publication number
WO2010041141A3
WO2010041141A3 PCT/IB2009/007184 IB2009007184W WO2010041141A3 WO 2010041141 A3 WO2010041141 A3 WO 2010041141A3 IB 2009007184 W IB2009007184 W IB 2009007184W WO 2010041141 A3 WO2010041141 A3 WO 2010041141A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
oil
formulations
based foamable
carriers
foamable carriers
Prior art date
Application number
PCT/IB2009/007184
Other languages
French (fr)
Other versions
WO2010041141A2 (en )
Inventor
Dov Tamarkin
David Schuz
Yohan Hazot
Elana Gazal
Original Assignee
Foamix Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • A61K9/122Foams; Dry foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

Abstract

A waterless foamable carrier and pharmaceutical composition which is suitable for external and internal administration is disclosed. The composition is single phase and includes at least one liquid oil; and a glyceride. Pharmaceutical compositions comprising active agents, methods for their preparation, propellants suitable for use with the carriers and uses thereof are further described.
PCT/IB2009/007184 2008-10-07 2009-10-06 Oil-based foamable carriers and formulations WO2010041141A3 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US10350008 true 2008-10-07 2008-10-07
US61/103,500 2008-10-07
US12084208 true 2008-12-08 2008-12-08
US61/120,842 2008-12-08

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13123213 US8518376B2 (en) 2007-12-07 2009-10-06 Oil-based foamable carriers and formulations
US13967546 US9795564B2 (en) 2007-12-07 2013-08-15 Oil-based foamable carriers and formulations

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
US12795164 Continuation-In-Part US8343945B2 (en) 2007-12-07 2010-06-07 Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
US12795213 Continuation-In-Part US8900553B2 (en) 2007-12-07 2010-06-07 Oil and liquid silicone foamable carriers and formulations

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US13123213 A-371-Of-International US8518376B2 (en) 2007-12-07 2009-10-06 Oil-based foamable carriers and formulations
US201113123213 A-371-Of-International 2011-07-18 2011-07-18
US13967546 Continuation US9795564B2 (en) 2007-12-07 2013-08-15 Oil-based foamable carriers and formulations

Publications (2)

Publication Number Publication Date
WO2010041141A2 true WO2010041141A2 (en) 2010-04-15
WO2010041141A3 true true WO2010041141A3 (en) 2010-06-17

Family

ID=42027763

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/007184 WO2010041141A3 (en) 2008-10-07 2009-10-06 Oil-based foamable carriers and formulations

Country Status (2)

Country Link
US (1) US8518376B2 (en)
WO (1) WO2010041141A3 (en)

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US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
CA2502986C (en) 2002-10-25 2011-08-23 Foamix Ltd. Cosmetic and pharmaceutical foam
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US20080138296A1 (en) * 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US20070020213A1 (en) 2002-10-25 2007-01-25 Foamix Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US20080031907A1 (en) * 2002-10-25 2008-02-07 Foamix Ltd. Cosmetic and pharmaceutical foam
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A3 (en) 2007-11-30 2009-11-12 Foamix Ltd. Foam containing benzoyl peroxide
WO2009072007A3 (en) * 2007-12-07 2009-11-12 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
WO2009090558A3 (en) 2008-01-14 2010-12-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
WO2010041141A3 (en) 2008-10-07 2010-06-17 Foamix Ltd. Oil-based foamable carriers and formulations
CA2760186A1 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
WO2011013009A4 (en) 2009-07-29 2011-06-23 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013008A4 (en) 2009-07-29 2011-07-14 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
US8871184B2 (en) 2009-10-02 2014-10-28 Foamix Ltd. Topical tetracycline compositions
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
US20120115821A1 (en) 2010-11-04 2012-05-10 442 Ventures, Llc Composition and method for treating skin conditions
US9931289B2 (en) * 2011-02-09 2018-04-03 Forward Scout Enterprises Pty Ltd Cosmetic or pharmaceutical formulation
US20120316518A1 (en) * 2011-06-09 2012-12-13 Pierre Croizat Wound dressing, containing nonwoven fabric and ointment base for negative pressure therapy
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US8633178B2 (en) 2011-11-23 2014-01-21 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150133421A1 (en) 2012-11-21 2015-05-14 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US8454942B1 (en) 2011-11-29 2013-06-04 L'oreal Cosmetic oil mousse composition
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US9919002B2 (en) 2013-10-21 2018-03-20 North Carolina State University Methods and constructs for compound delivery
CA2951284A1 (en) 2014-07-29 2016-02-04 Therapeuticsmd, Inc. Transdermal cream
CA2982176A1 (en) * 2015-04-09 2016-10-13 Neostem Oncology, Llc Stem cell compositions for cosmetic and dermatologic use
CA3020153A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition

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