WO2009063931A1 - 血行促進作用の評価方法、血行促進物質のスクリーニング方法、および血行促進剤 - Google Patents
血行促進作用の評価方法、血行促進物質のスクリーニング方法、および血行促進剤 Download PDFInfo
- Publication number
- WO2009063931A1 WO2009063931A1 PCT/JP2008/070657 JP2008070657W WO2009063931A1 WO 2009063931 A1 WO2009063931 A1 WO 2009063931A1 JP 2008070657 W JP2008070657 W JP 2008070657W WO 2009063931 A1 WO2009063931 A1 WO 2009063931A1
- Authority
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- WIPO (PCT)
- Prior art keywords
- blood circulation
- substance
- promoting
- activity
- promoting activity
- Prior art date
Links
- 239000000126 substance Substances 0.000 title abstract 9
- 239000008280 blood Substances 0.000 title abstract 8
- 210000004369 blood Anatomy 0.000 title abstract 8
- 230000000694 effects Effects 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 6
- 238000011156 evaluation Methods 0.000 title abstract 4
- 230000017531 blood circulation Effects 0.000 title abstract 2
- 238000012216 screening Methods 0.000 title abstract 2
- WRYLYDPHFGVWKC-UHFFFAOYSA-N 4-terpineol Chemical compound CC(C)C1(O)CCC(C)=CC1 WRYLYDPHFGVWKC-UHFFFAOYSA-N 0.000 abstract 2
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 2
- 230000002500 effect on skin Effects 0.000 abstract 2
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 abstract 2
- 210000005036 nerve Anatomy 0.000 abstract 2
- 230000002889 sympathetic effect Effects 0.000 abstract 2
- 239000001695 (2E)-1,1-dimethoxy-3,7-dimethylocta-2,6-diene Substances 0.000 abstract 1
- ZSKAJFSSXURRGL-PKNBQFBNSA-N (2e)-1,1-dimethoxy-3,7-dimethylocta-2,6-diene Chemical compound COC(OC)\C=C(/C)CCC=C(C)C ZSKAJFSSXURRGL-PKNBQFBNSA-N 0.000 abstract 1
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 abstract 1
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 abstract 1
- WUOACPNHFRMFPN-SECBINFHSA-N (S)-(-)-alpha-terpineol Chemical compound CC1=CC[C@@H](C(C)(C)O)CC1 WUOACPNHFRMFPN-SECBINFHSA-N 0.000 abstract 1
- WRYLYDPHFGVWKC-SNVBAGLBSA-N 4-Terpineol Natural products CC(C)[C@]1(O)CCC(C)=CC1 WRYLYDPHFGVWKC-SNVBAGLBSA-N 0.000 abstract 1
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 abstract 1
- 239000005792 Geraniol Substances 0.000 abstract 1
- GLZPCOQZEFWAFX-YFHOEESVSA-N Geraniol Natural products CC(C)=CCC\C(C)=C/CO GLZPCOQZEFWAFX-YFHOEESVSA-N 0.000 abstract 1
- OVKDFILSBMEKLT-UHFFFAOYSA-N alpha-Terpineol Natural products CC(=C)C1(O)CCC(C)=CC1 OVKDFILSBMEKLT-UHFFFAOYSA-N 0.000 abstract 1
- 229940088601 alpha-terpineol Drugs 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 229940043350 citral Drugs 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 abstract 1
- 229940113087 geraniol Drugs 0.000 abstract 1
- 229930007744 linalool Natural products 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/026—Measuring blood flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Vascular Medicine (AREA)
- Physiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-297340 | 2007-11-15 | ||
JP2007297340 | 2007-11-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009063931A1 true WO2009063931A1 (ja) | 2009-05-22 |
Family
ID=40638778
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/070657 WO2009063931A1 (ja) | 2007-11-15 | 2008-11-13 | 血行促進作用の評価方法、血行促進物質のスクリーニング方法、および血行促進剤 |
Country Status (2)
Country | Link |
---|---|
JP (1) | JP5504388B2 (enrdf_load_stackoverflow) |
WO (1) | WO2009063931A1 (enrdf_load_stackoverflow) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013018719A (ja) * | 2011-07-08 | 2013-01-31 | Kao Corp | 皮膚血行促進化粧料 |
US20130149399A1 (en) * | 2010-05-31 | 2013-06-13 | Shiseido Company ,Ltd. | Skin temperature elevating agent, and cosmetic composition, food and sundry article containing the same |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6017330B2 (ja) * | 2013-01-30 | 2016-10-26 | 花王株式会社 | 過活動膀胱の予防又は改善剤 |
JP2015196031A (ja) * | 2014-04-03 | 2015-11-09 | 有限会社日本健康科学研究センター | 冷え性、及び、むくみ改善の為の足浴用袋製剤。 |
KR102561733B1 (ko) * | 2023-04-03 | 2023-07-31 | 한국 한의학 연구원 | 고추 부산물 추출물을 유효성분으로 함유하는 혈행 개선용 조성물 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10310528A (ja) * | 1997-03-12 | 1998-11-24 | Hayashibara Takeshi | 血行改善剤 |
JP2000044467A (ja) * | 1998-07-31 | 2000-02-15 | Lion Corp | 血流促進剤 |
JP2001213717A (ja) * | 2000-01-28 | 2001-08-07 | Kao Corp | 血行促進剤 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06234628A (ja) * | 1993-02-09 | 1994-08-23 | Kao Corp | 皮膚外用剤 |
JP2003095985A (ja) * | 2001-09-26 | 2003-04-03 | Lion Corp | 血行促進組成物 |
JP2005206596A (ja) * | 2003-12-26 | 2005-08-04 | Osaka Industrial Promotion Organization | 芳香療法用組成物 |
-
2008
- 2008-11-12 JP JP2008290266A patent/JP5504388B2/ja active Active
- 2008-11-13 WO PCT/JP2008/070657 patent/WO2009063931A1/ja active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10310528A (ja) * | 1997-03-12 | 1998-11-24 | Hayashibara Takeshi | 血行改善剤 |
JP2000044467A (ja) * | 1998-07-31 | 2000-02-15 | Lion Corp | 血流促進剤 |
JP2001213717A (ja) * | 2000-01-28 | 2001-08-07 | Kao Corp | 血行促進剤 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130149399A1 (en) * | 2010-05-31 | 2013-06-13 | Shiseido Company ,Ltd. | Skin temperature elevating agent, and cosmetic composition, food and sundry article containing the same |
JP2013018719A (ja) * | 2011-07-08 | 2013-01-31 | Kao Corp | 皮膚血行促進化粧料 |
Also Published As
Publication number | Publication date |
---|---|
JP5504388B2 (ja) | 2014-05-28 |
JP2009139371A (ja) | 2009-06-25 |
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