WO2009048073A1 - Procédé d'enrobage de granules - Google Patents
Procédé d'enrobage de granules Download PDFInfo
- Publication number
- WO2009048073A1 WO2009048073A1 PCT/JP2008/068291 JP2008068291W WO2009048073A1 WO 2009048073 A1 WO2009048073 A1 WO 2009048073A1 JP 2008068291 W JP2008068291 W JP 2008068291W WO 2009048073 A1 WO2009048073 A1 WO 2009048073A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- water
- coating
- organic solvent
- active substance
- physiologically active
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Abstract
Cette invention concerne un procédé d'enrobage dans lequel le profil d'élution de l'agent principal des granules contenant une substance physiologiquement active est contrôlé en recouvrant des noyaux contenant la substance physiologiquement active par pulvérisation d'une solution d'enrobage qui contient un polymère insoluble dans l'eau, un solvant organique ayant un point d'ébullition d'au moins 50 °C et de l'eau où le rapport des teneurs en poids du solvant organique sur l'eau vaut environ 89/11 à environ 50/50.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007263185 | 2007-10-09 | ||
JP2007-263185 | 2007-10-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009048073A1 true WO2009048073A1 (fr) | 2009-04-16 |
Family
ID=40549217
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/068291 WO2009048073A1 (fr) | 2007-10-09 | 2008-10-08 | Procédé d'enrobage de granules |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2009048073A1 (fr) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010280589A (ja) * | 2009-06-03 | 2010-12-16 | Ohara Yakuhin Kogyo Kk | 生理活性物質含有粒子の製造方法 |
JP2012046454A (ja) * | 2010-08-27 | 2012-03-08 | Lion Corp | 内服用錠剤およびその製造方法 |
WO2018045103A1 (fr) * | 2016-08-30 | 2018-03-08 | Allergan, Inc. | Procédé de fabrication de billes enrobées |
US11078085B2 (en) | 2016-05-26 | 2021-08-03 | Allergan, Inc. | Production of rounded salt particles |
WO2023209606A1 (fr) * | 2022-04-29 | 2023-11-02 | Illumina Cambridge Limited | Procédés et systèmes d'encapsulation de microsphères lyophilisées |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH021405A (ja) * | 1988-03-31 | 1990-01-05 | Tanabe Seiyaku Co Ltd | 放出制御型製剤およびその製法 |
JPH05194225A (ja) * | 1991-11-07 | 1993-08-03 | Yoshitomi Pharmaceut Ind Ltd | 安定化された抗潰瘍剤含有製剤 |
WO1994010983A1 (fr) * | 1992-11-06 | 1994-05-26 | Hisamitsu Pharmaceutical Co., Inc. | Preparation pharmaceutique perorale liberable dans le tube digestif inferieur |
JPH08109126A (ja) * | 1994-10-07 | 1996-04-30 | Amano Pharmaceut Co Ltd | 耐衝撃性腸溶性顆粒剤およびこれを含有する錠剤 |
JPH08259446A (ja) * | 1995-01-24 | 1996-10-08 | Mitsui Toatsu Chem Inc | 持効性医薬製剤 |
JPH09295933A (ja) * | 1996-03-07 | 1997-11-18 | Takeda Chem Ind Ltd | 放出制御組成物 |
JPH10231242A (ja) * | 1997-02-20 | 1998-09-02 | Taiyo Yakuhin Kogyo Kk | 持続性ジクロフェナクナトリウム組成物 |
JP2002363080A (ja) * | 2001-06-08 | 2002-12-18 | Towa Yakuhin Kk | 安定な内服用抗潰瘍製剤の製造法 |
JP2007519741A (ja) * | 2004-01-29 | 2007-07-19 | ヤマノウチ・ファーマ・テクノロジーズ・インク | 胃腸特異的複数薬物放出システム |
-
2008
- 2008-10-08 WO PCT/JP2008/068291 patent/WO2009048073A1/fr active Application Filing
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH021405A (ja) * | 1988-03-31 | 1990-01-05 | Tanabe Seiyaku Co Ltd | 放出制御型製剤およびその製法 |
JPH05194225A (ja) * | 1991-11-07 | 1993-08-03 | Yoshitomi Pharmaceut Ind Ltd | 安定化された抗潰瘍剤含有製剤 |
WO1994010983A1 (fr) * | 1992-11-06 | 1994-05-26 | Hisamitsu Pharmaceutical Co., Inc. | Preparation pharmaceutique perorale liberable dans le tube digestif inferieur |
JPH08109126A (ja) * | 1994-10-07 | 1996-04-30 | Amano Pharmaceut Co Ltd | 耐衝撃性腸溶性顆粒剤およびこれを含有する錠剤 |
JPH08259446A (ja) * | 1995-01-24 | 1996-10-08 | Mitsui Toatsu Chem Inc | 持効性医薬製剤 |
JPH09295933A (ja) * | 1996-03-07 | 1997-11-18 | Takeda Chem Ind Ltd | 放出制御組成物 |
JPH10231242A (ja) * | 1997-02-20 | 1998-09-02 | Taiyo Yakuhin Kogyo Kk | 持続性ジクロフェナクナトリウム組成物 |
JP2002363080A (ja) * | 2001-06-08 | 2002-12-18 | Towa Yakuhin Kk | 安定な内服用抗潰瘍製剤の製造法 |
JP2007519741A (ja) * | 2004-01-29 | 2007-07-19 | ヤマノウチ・ファーマ・テクノロジーズ・インク | 胃腸特異的複数薬物放出システム |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010280589A (ja) * | 2009-06-03 | 2010-12-16 | Ohara Yakuhin Kogyo Kk | 生理活性物質含有粒子の製造方法 |
JP2012046454A (ja) * | 2010-08-27 | 2012-03-08 | Lion Corp | 内服用錠剤およびその製造方法 |
US11078085B2 (en) | 2016-05-26 | 2021-08-03 | Allergan, Inc. | Production of rounded salt particles |
WO2018045103A1 (fr) * | 2016-08-30 | 2018-03-08 | Allergan, Inc. | Procédé de fabrication de billes enrobées |
WO2023209606A1 (fr) * | 2022-04-29 | 2023-11-02 | Illumina Cambridge Limited | Procédés et systèmes d'encapsulation de microsphères lyophilisées |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2006085335A3 (fr) | Composition pharmaceutique de substances labiles acides | |
WO2012027140A3 (fr) | Formulation antimicrobienne | |
WO2010106314A3 (fr) | Formulation | |
WO2009048073A1 (fr) | Procédé d'enrobage de granules | |
WO2007107981A3 (fr) | Procedes, compositions et dispositifs pour maintenir l'equilibre chimique de l'eau chloree | |
WO2010040834A3 (fr) | Formulations phytoprotectrices aqueuses liquides | |
WO2010056065A3 (fr) | Procédé de préparation de microsphères et microsphères produites par ce procédé | |
WO2007067044A3 (fr) | Capsules/comprimes contenant des principes actifs modifies | |
WO2009074735A3 (fr) | Utilisation d'un nouvel agent naturel dans des compositions cosmetiques | |
WO2006108861A3 (fr) | Solubilite de la cellulose dans des liquides ioniques, sous apport de base amine | |
WO2009001085A3 (fr) | Composition inhalable | |
NZ597710A (en) | Meso-sized capsules useful for the delivery of agricultural chemicals | |
WO2005118008A3 (fr) | Compositions et articles contenant une matrice polymere reticulee et un liquide actif immobilise et procedes de fabrication et d'utilisation de ceux-ci | |
WO2007122625A3 (fr) | Préparations solides multifonctionnelles pour traitement de l'eau | |
WO2011018583A3 (fr) | Nouvelles formulations pharmaceutiques contre le mésusage des médicaments | |
WO2005077337A3 (fr) | Dispersions preparees avec des agents autostabilisants | |
WO2008140262A3 (fr) | Utilisation d'un tensioactif biologique en tant qu'agent anti-inflammatoire et solution de conservation de tissus | |
WO2009126301A3 (fr) | Libération contrôlée d’agents actifs à partir d’oléosomes | |
WO2010007239A3 (fr) | Procédé de lutte contre les insectes du sol | |
WO2009066588A1 (fr) | Composition aqueuse de résine pour revêtement et revêtement aqueux | |
TR200806590A2 (tr) | Tarım ilacı bileşimleri | |
WO2009113712A3 (fr) | Compositions pesticides | |
WO2009058717A3 (fr) | Procédés de fabrication de compositions pesticides | |
MX2010003357A (es) | Metodos para preparar productos granulados de control de malezas que tienen distribucion mejorada de ingredientes agriculturalmente activos revestidos sobre los mismos. | |
GB2460590B (en) | Adjuvant composition, agrochemical spray aqueous solution containing the same and control method using the same |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 08837401 Country of ref document: EP Kind code of ref document: A1 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 08837401 Country of ref document: EP Kind code of ref document: A1 |
|
NENP | Non-entry into the national phase |
Ref country code: JP |