WO2008102639A1 - グルコースの電気化学的定量方法、グルコース脱水素酵素組成物、及び、グルコース測定用電気化学センサー - Google Patents
グルコースの電気化学的定量方法、グルコース脱水素酵素組成物、及び、グルコース測定用電気化学センサー Download PDFInfo
- Publication number
- WO2008102639A1 WO2008102639A1 PCT/JP2008/051850 JP2008051850W WO2008102639A1 WO 2008102639 A1 WO2008102639 A1 WO 2008102639A1 JP 2008051850 W JP2008051850 W JP 2008051850W WO 2008102639 A1 WO2008102639 A1 WO 2008102639A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- glucose
- electrochemical
- quantification
- determination
- dehydrogenase composition
- Prior art date
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title abstract 3
- 108010050375 Glucose 1-Dehydrogenase Proteins 0.000 title abstract 3
- 239000008103 glucose Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000011002 quantification Methods 0.000 title abstract 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 title 1
- 240000006439 Aspergillus oryzae Species 0.000 abstract 1
- 235000002247 Aspergillus oryzae Nutrition 0.000 abstract 1
- 241001465318 Aspergillus terreus Species 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 239000005515 coenzyme Substances 0.000 abstract 1
- -1 flavin compound Chemical class 0.000 abstract 1
- 238000004313 potentiometry Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
- C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
- G01N2333/38—Assays involving biological materials from specific organisms or of a specific nature from fungi from Aspergillus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
Abstract
フラビン化合物を補酵素として必要とするグルコース脱水素酵素を用いて、ポテンショメトリーによる電位測定を行うことを特徴とする溶液中のグルコースの定量方法であり、糸状菌由来で、特にアスペルギルス・オリゼ(Aspergillus oryzae)、または、アスペルギルス・テレウス(Aspergillus terreus)由来のグルコース脱水素酵素を用いて定量する事が好ましい。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009500128A JPWO2008102639A1 (ja) | 2007-02-20 | 2008-02-05 | グルコースの電気化学的定量方法、グルコース脱水素酵素組成物、及び、グルコース測定用電気化学センサー |
Applications Claiming Priority (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007039133 | 2007-02-20 | ||
JP2007-039133 | 2007-02-20 | ||
JP2007075022 | 2007-03-22 | ||
JP2007-075023 | 2007-03-22 | ||
JP2007075023 | 2007-03-22 | ||
JP2007-075022 | 2007-03-22 | ||
US90885207P | 2007-03-29 | 2007-03-29 | |
US60/908,852 | 2007-03-29 | ||
JP2007118423 | 2007-04-27 | ||
JP2007-118423 | 2007-04-27 | ||
JP2007132488 | 2007-05-18 | ||
JP2007-132488 | 2007-05-18 | ||
JP2007313048 | 2007-12-04 | ||
JP2007-313048 | 2007-12-04 | ||
JP2007-313047 | 2007-12-04 | ||
JP2007313047 | 2007-12-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008102639A1 true WO2008102639A1 (ja) | 2008-08-28 |
Family
ID=39709917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/051850 WO2008102639A1 (ja) | 2007-02-20 | 2008-02-05 | グルコースの電気化学的定量方法、グルコース脱水素酵素組成物、及び、グルコース測定用電気化学センサー |
Country Status (3)
Country | Link |
---|---|
US (1) | US20080248514A1 (ja) |
JP (1) | JPWO2008102639A1 (ja) |
WO (1) | WO2008102639A1 (ja) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009119728A1 (ja) * | 2008-03-27 | 2009-10-01 | 東洋紡績株式会社 | 糸状菌由来フラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼ(fadgdh) |
WO2010053161A1 (ja) * | 2008-11-06 | 2010-05-14 | ユニチカ株式会社 | 改変型フラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼ |
WO2011034108A1 (ja) * | 2009-09-16 | 2011-03-24 | 東洋紡績株式会社 | 改変型フラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼ |
JP2011097931A (ja) * | 2009-10-09 | 2011-05-19 | Toyobo Co Ltd | Fadジヌクレオチド依存性グルコースデヒドロゲナーゼの温度依存性を改善する方法 |
JP2013083587A (ja) * | 2011-10-12 | 2013-05-09 | Nipro Corp | 生体試料測定装置及び測定方法 |
EP2844747A1 (en) * | 2012-05-03 | 2015-03-11 | Roche Diagniostics GmbH | A glycosylated modified flavin adenine dinucleotide dependent glucose dehydrogenase |
JP2020022913A (ja) * | 2016-04-27 | 2020-02-13 | Phcホールディングス株式会社 | バイオセンサ |
CN113552198A (zh) * | 2021-05-31 | 2021-10-26 | 武汉维尔博生物科技有限公司 | 一种基于高响应葡萄糖适配体的电化学传感器及其制备方法 |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7514250B2 (en) | 2002-12-24 | 2009-04-07 | Ikeda Food Research Co., Ltd. | Coenzyme-binding glucose dehydrogenase |
JP5020070B2 (ja) | 2005-03-25 | 2012-09-05 | 池田食研株式会社 | 補酵素結合型グルコース脱水素酵素をコードするポリヌクレオチド |
WO2008059777A1 (fr) * | 2006-11-14 | 2008-05-22 | Toyo Boseki Kabushiki Kaisha | Glucose déshydrogénase dépendante du flavine-adénine dinucléotide modifiée |
CN103003440B (zh) * | 2010-07-23 | 2015-11-25 | 霍夫曼-拉罗奇有限公司 | 含两性离子缓冲液的组合物及其在电分析装置和方法中的用途 |
JP5584740B2 (ja) | 2011-09-26 | 2014-09-03 | アークレイ株式会社 | グルコースセンサ |
CN104661731B (zh) | 2012-08-07 | 2017-03-01 | 生物辐射实验室股份有限公司 | 用于电泳中免染蛋白质检测的改良电极缓冲液 |
US10793820B2 (en) * | 2013-04-30 | 2020-10-06 | Lawrence Livermore National Security, Llc | Miniaturized, automated in-vitro tissue bioreactor |
GB2539224A (en) * | 2015-06-09 | 2016-12-14 | Giuseppe Occhipinti Luigi | Method of forming a chemical sensor device and device |
US10365242B2 (en) * | 2017-10-04 | 2019-07-30 | King Fahd University Of Petroleum And Minerals | Electrochemical cell for detecting hydroquinone |
CN113588935A (zh) * | 2021-07-12 | 2021-11-02 | 成都云芯医联科技有限公司 | 一种电化学免条码血糖试纸及其制备方法 |
CN115201308B (zh) * | 2022-07-18 | 2024-01-26 | 山东省医疗器械和药品包装检验研究院 | 一种持续葡萄糖监测系统稳定性评价系统及方法 |
Citations (4)
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JPH01203962A (ja) * | 1988-02-10 | 1989-08-16 | Nec Corp | 免疫化学的測定法 |
JPH0622793A (ja) * | 1990-07-19 | 1994-02-01 | Miles Inc | 導電センサーおよびそれらの診断用検定への使用 |
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WO2004058958A1 (ja) * | 2002-12-24 | 2004-07-15 | Ikeda Food Research Co., Ltd. | 補酵素結合型グルコース脱水素酵素 |
-
2008
- 2008-02-05 WO PCT/JP2008/051850 patent/WO2008102639A1/ja active Application Filing
- 2008-02-05 JP JP2009500128A patent/JPWO2008102639A1/ja active Pending
- 2008-02-15 US US12/031,834 patent/US20080248514A1/en not_active Abandoned
Patent Citations (4)
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JPH01203962A (ja) * | 1988-02-10 | 1989-08-16 | Nec Corp | 免疫化学的測定法 |
JPH0622793A (ja) * | 1990-07-19 | 1994-02-01 | Miles Inc | 導電センサーおよびそれらの診断用検定への使用 |
JP2001252095A (ja) * | 2000-03-14 | 2001-09-18 | Asahi Kasei Corp | 微量成分の測定法及びそれに用いる組成物 |
WO2004058958A1 (ja) * | 2002-12-24 | 2004-07-15 | Ikeda Food Research Co., Ltd. | 補酵素結合型グルコース脱水素酵素 |
Non-Patent Citations (5)
Title |
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KOJIMA S. ET AL.: "Fundamental study for an oxygen-insensitive amperometric glucose sensor using a novel glucose dehydrogenase", CHEMICAL SENSORS, vol. 20, no. SUPPL. B, 2004, pages 768 - 769, XP003004574 * |
OKUMURA N. ET AL.: "FAD Izongata Glucose Dehydrogenase to Mediator tono Hanno Tokusei ni Kansuru Ichikosatsu", REVIEW OF POLAROGRAPHY, vol. 51, no. 3, 2005, pages 193 * |
TSUJIMURA S. ET AL.: "Novel FAD-Dependent Glucose Dehydrogenase for a Dioxygen-Insentive Glucose Biosensor", BIOSCI. BIOTECHNOL. BIOCHEM., vol. 70, no. 3, 2006, pages 654 - 659, XP003004577 * |
TSUJIMURA S. ET AL.: "Potential-step coulometry of D-glucose using a novel FAD-dependent glucose dehydrogenase", ANAL. BIOANAL. CHEM., vol. 386, 2006, pages 645 - 651, XP019441071 * |
TSUJIMURA S. ET AL.: "Shinki Glucose Dehydrogenase o Mochiita Coulometry ni yoru Glucose no Zettai Teiryo", THE ELECTROCHEMICAL SOCIETY OF JAPAN TAIKAI KOEN YOSHISHU, 2005, pages 117 * |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009119728A1 (ja) * | 2008-03-27 | 2009-10-01 | 東洋紡績株式会社 | 糸状菌由来フラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼ(fadgdh) |
WO2010053161A1 (ja) * | 2008-11-06 | 2010-05-14 | ユニチカ株式会社 | 改変型フラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼ |
WO2011034108A1 (ja) * | 2009-09-16 | 2011-03-24 | 東洋紡績株式会社 | 改変型フラビンアデニンジヌクレオチド依存性グルコースデヒドロゲナーゼ |
US8247189B2 (en) | 2009-09-16 | 2012-08-21 | Toyo Boseki Kabushiki Kaisha | Modified flavin adenine dinucleotide-dependent glucose dehydrogenase |
JP2011097931A (ja) * | 2009-10-09 | 2011-05-19 | Toyobo Co Ltd | Fadジヌクレオチド依存性グルコースデヒドロゲナーゼの温度依存性を改善する方法 |
JP2013083587A (ja) * | 2011-10-12 | 2013-05-09 | Nipro Corp | 生体試料測定装置及び測定方法 |
EP2844747A1 (en) * | 2012-05-03 | 2015-03-11 | Roche Diagniostics GmbH | A glycosylated modified flavin adenine dinucleotide dependent glucose dehydrogenase |
JP2015519892A (ja) * | 2012-05-03 | 2015-07-16 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | グリコシル化されている修飾フラビンアデニンジヌクレオチド依存性グルコース脱水素酵素 |
EP2844747B1 (en) * | 2012-05-03 | 2019-03-20 | Roche Diabetes Care GmbH | A glycosylated modified flavin adenine dinucleotide dependent glucose dehydrogenase |
JP2020022913A (ja) * | 2016-04-27 | 2020-02-13 | Phcホールディングス株式会社 | バイオセンサ |
US11369412B2 (en) | 2016-04-27 | 2022-06-28 | Phc Holdings Corporation | Sensor insertion device and biosensor |
CN113552198A (zh) * | 2021-05-31 | 2021-10-26 | 武汉维尔博生物科技有限公司 | 一种基于高响应葡萄糖适配体的电化学传感器及其制备方法 |
CN113552198B (zh) * | 2021-05-31 | 2024-03-26 | 武汉维尔博生物科技有限公司 | 一种基于高响应葡萄糖适配体的电化学传感器及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
US20080248514A1 (en) | 2008-10-09 |
JPWO2008102639A1 (ja) | 2010-05-27 |
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