WO2008067576A2 - Verpackung für kleinvolumige flaschen - Google Patents
Verpackung für kleinvolumige flaschen Download PDFInfo
- Publication number
- WO2008067576A2 WO2008067576A2 PCT/AT2007/000545 AT2007000545W WO2008067576A2 WO 2008067576 A2 WO2008067576 A2 WO 2008067576A2 AT 2007000545 W AT2007000545 W AT 2007000545W WO 2008067576 A2 WO2008067576 A2 WO 2008067576A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- packaging
- bottles
- packaging part
- bottle
- parts
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D75/321—Both sheets being recessed
- B65D75/323—Both sheets being recessed and forming several compartments
Definitions
- the present invention relates to a packaging for small-volume bottles, such as ampoules, with a first packaging part for receiving the lower portion of at least two bottles and a second packaging part for receiving the upper portion of at least two bottles, wherein the first and the second packaging part each at least two having recesses spaced apart from one another, which depressions are molded into the packaging part in a dimensionally stable manner and surrounded by substantially planar webs at their openings, the first and second packaging parts being fluid-tightly and detachably connected to one another via these webs.
- Bottles with health-related content e.g. toxic or cytotoxic substances, etc., pose a significant risk to unprotected handling personnel.
- the outside of the bottle may be wetted with the contents, with the risk of contamination during handling ,
- the package includes a container for holding the bottle and a A closure cap for sealing the container, both the container and the closure cap being provided with spacer ribs distributed over its inner circumference, which hold a received bottle at a distance from the inner periphery of the container and with a press fit, the closure cap further comprising a closure of the Bottle overflows.
- cytotoxic substances are often concentrated and bottled and transported in small quantities. Only immediately before the application, ie the treatment of the patient, the substances are removed and diluted for infusion or injection purposes.
- ampoules having a capacity of 1 to 20 ml are used.
- ampoules such as piercing ampoules made of glass or plastic, which are also referred to as vials.
- These ampoules are closed with a rubber stopper, which is held with a crimp cap made of aluminum or plastic and can be pierced, for example by means of a cannula, to remove the contents of the bottle.
- specially designed adapters are available for removing the contents from such ampoules.
- a further development of known blister packs is the packaging of the European patent EP 0 703 157, which instead of the substantially planar cover layer provides a cover layer in which also molded recesses are present, so that form cavities in the closure of the blister packaging in which the pharmaceutical units are.
- This packaging should also be suitable for receiving ampoules, depending on the shape of the wells.
- the shape of the recesses in such a package alone does not ensure that ampoules containing, for example, health-relevant ingredients, such as toxic or cytotoxic substances, are kept safe during transport and subsequent handling.
- the invention therefore has for its object to provide a package for small-volume bottles, such as ampoules, which can accommodate at least two such bottles and ensures improved grip of the bottles during transport and subsequent handling.
- the invention further sets itself the goal of providing such a package, which is liquid-tight and thus leak-proof and material and cost-economical to produce.
- the recesses are provided with distributed over its circumference spacer ribs, which center the bottle and the closures at a distance from the inner circumference of the recess and with Hold the press fit.
- the spacer ribs are formed by indentations formed in a stable manner in the wall of the recess.
- a package which largely excludes a Nachaussendringen surface contamination of FIa see in their entire area due to the spacer construction and offers a leakage protection in the event of damage to the bottle.
- the support of the bottle during transport and during the removal of the upper part of the bottle forming the second packaging part is improved in a separation of the bottles and further handling of the bottle in the partially packaged state.
- the height of the depression in the first packaging part is smaller than the height of the bottle to be accommodated.
- the recesses have substantially the shape of a cylinder or a truncated cone.
- the clear width of the openings of the depressions in the first packaging part has a size such that it is possible to place conventional adapters onto, for example, the ampoules for taking out the contents, without the ampoule being removed from the first packaging part must become.
- the webs present between the depressions preferably have lines of weakening, such as perforations, in order to allow a separation of packaged bottles, for example by simply bending them off.
- the weakening lines in the webs preferably run centrally and parallel to the respective outer edges of the first and / or the second packaging part.
- the second packaging part preferably has a width greater than the first packaging part and notches or indentations at regular intervals at its longitudinal edges and has wings.
- the material from which the packaging according to the invention is made is preferably translucent or transparent plastic. This allows the integrity of the bottle and its level to be checked from the outside.
- the dimensional stability should be mentioned in order to avoid deformation of the depressions by impressions and thus possible damage to the bottle contained therein.
- the plastics must also be inert and resistant to them in the event of contact with the toxic content, whether due to contamination of the external surfaces of the bottle when it is filled or due to damage.
- plastics are further selected which are easy to process, such as thermoplastics, from which the packaging parts and the recesses provided therein by conventional methods of plastics technology, such as extrusion, pressing, injection molding, deep drawing, etc., can be made.
- Suitable plastic materials are, for example, polyethylene terephthalate, polystyrene, polyvinyl chloride, polycarbonate, polyamide, polyethylene and polypropylene, acrylic-butadiene-styrene copolymer, impact-resistant polystyrene, styrene-acrylonitrile copolymer and a graft polymer of styrene and acrylonitrile on acrylic rubber.
- molded-in recesses are provided in the packaging according to the invention in the corner regions of the first and / or the second packaging part, the height of which is less than the height of the recesses for mounting. would be the bottles. These recesses ensure that the packaging parts are held at a predefined distance from one another during stacking prior to their use, and so also that deformations of the recesses for receiving the bottles are avoided.
- the second packaging part When packaging the bottles they are automatically inserted in a known manner in the first packaging part. Subsequently, the second packaging part is placed precisely over it and the two parts of the packaging are detachably connected to one another on the webs in a known manner.
- the connection of the two packaging parts is such as to ensure an intact connection, which is unsolvable by the normal stress during transport and handling in the packaged state, which is furthermore liquid-tight, but at the same time a detachment or removal of the second packaging part from the first packaging part without excessive effort is possible.
- sterilization of the individual packaging parts, the bottles and / or the filled and sealed packaging is preferably carried out by customary means, for example by UV irradiation or ionizing radiation, in order to provide ready-to-use sterile bottles.
- customary means for example by UV irradiation or ionizing radiation.
- the usual wiping disinfection of the puncture site in the septum prior to insertion of the Injektornadel can be avoided.
- sterilization of the internal sections and areas of the packaging according to the invention is ensured by this measure.
- the method for packaging small-volume bottles includes the steps of blending first and second packaging parts, placing bottles in the first packaging parts, placing the second packaging parts on the bottle-filled first packaging parts, joining the first and second packaging parts the method further comprises one or more sterilization steps which can be performed on the first and second packaging parts, the bottles, the bottle-filled first packaging parts and / or the bottle-filled and optionally sealed packaging.
- the package of the invention is preferably used for packaging small volume bottles, such as vials, having cytotoxic content.
- the filled package according to the invention is stackable in the usual way, whereby a packaging of several such packages in an overpack, such as a cardboard packaging, is possible.
- Fig. 1 is a perspective view of an inventive
- Fig. 2 is a plan view of the package according to the invention
- Fig. 3 is a bottom view of the package according to the invention
- 4 and 5 shows sectional views of the cavities formed by the depressions along the line AA or C to C;
- FIG. 6 shows a sectional view of the recesses provided in the corner regions for improving the stackability.
- FIG. 7 shows an isolated element of the packaging according to the invention in a perspective view
- Fig. 8 is an isolated element of the first packaging part (without content) in a perspective view
- FIG. 9 and FIG. 10 shows an isolated element of the first packaging part, which contains a bottle with conventional adapters, in each case in a perspective view.
- FIG. 1 shows a perspective view of a packaging 1 according to the invention with a first packaging part 2 and a second packaging part 3.
- the packaging parts 2 and 3 recesses 4, 4 'are provided.
- the depressions 4, 4 ' have the shape of a truncated cone and rib-shaped indentations 5, 5' along their circumference.
- two of the corner regions are preferably truncated conical recesses 6, 6 'provided for improved stacking of the packaging parts.
- the second packaging part 3 has indentations 7 at its two longitudinal edges, which indentations (not shown) can also be embodied in the same way.
- wings 8 are formed at both longitudinal edges of the second packaging part, which detachment of the second packaging part 3 from the first Packaging part 2 easier.
- the wings 8 can have any shape and dimension as long as they can be gripped with the hands or a tool.
- the recesses 4 ' are arranged spaced from each other in two likewise mutually parallel rows.
- the weakening lines 9 ' preferably extend centrally in the webs 10' and parallel to the longitudinal edge of a rectangle to be inscribed in the second packaging part 3.
- 3 shows the packaging according to the invention in a bottom view. As can be seen from this view, the first packaging part 2 has a smaller width than the second packaging part 3, which opens up the possibility of providing the indentations 7 and the wings 8 exclusively on the second packaging part 3.
- the first packaging part 2 also has two mutually parallel and to the outer edge of the packaging part 2 extending rows of depressions 4, around the openings webs 10 are formed.
- the first packaging part 2 also has weakening lines 9.
- each five indentations 5, in the recesses 4 'of the second packaging part 3 each three molded indentations 5 'are provided.
- the bottle 12 is centered and fixed by the molded rib-shaped indentations 5, 5' at a distance from the inner circumference of the recesses.
- the bottle shown is a standard piercing ampule.
- the packaging 1 enables the separation of the bottles 12 in the packaged state. Such a singulated element is shown in FIG.
- the first packaging part 2 corresponding to this individual element is shown (without contents) in FIG. 8.
- the recesses 4 preferably have inner diameters at their openings, which allow the bottles 12 to be provided with known adapters, for example for removal or dilution, without the bottles 12 having to be removed from the first packaging part 2 for the purpose of safe handling of the bottles 12 contributes.
- the packaging 1 may be not only rectangular but may also have a square shape and a number of recesses 4, 4 'different in number from the number shown.
Landscapes
- Chemical & Material Sciences (AREA)
- Composite Materials (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Packages (AREA)
- Stackable Containers (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/517,548 US20100155271A1 (en) | 2006-12-04 | 2007-12-04 | Packaging for Small Bottles |
EP07845276A EP2121473A2 (de) | 2006-12-04 | 2007-12-04 | Verpackung für kleinvolumige flaschen |
AU2007329159A AU2007329159A1 (en) | 2006-12-04 | 2007-12-04 | Packaging for small bottles |
CA2707532A CA2707532A1 (en) | 2006-12-04 | 2007-12-04 | Packaging for low-volume bottles |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0200906A AT504573B1 (de) | 2006-12-04 | 2006-12-04 | Verpackung für kleinvolumige flaschen |
ATA2009/2006 | 2006-12-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008067576A2 true WO2008067576A2 (de) | 2008-06-12 |
WO2008067576A3 WO2008067576A3 (de) | 2008-10-09 |
Family
ID=39064399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/AT2007/000545 WO2008067576A2 (de) | 2006-12-04 | 2007-12-04 | Verpackung für kleinvolumige flaschen |
Country Status (6)
Country | Link |
---|---|
US (1) | US20100155271A1 (de) |
EP (1) | EP2121473A2 (de) |
AT (1) | AT504573B1 (de) |
AU (1) | AU2007329159A1 (de) |
CA (1) | CA2707532A1 (de) |
WO (1) | WO2008067576A2 (de) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH702668A1 (de) * | 2010-02-04 | 2011-08-15 | Christian Schuetz | Setverpackung zum sterilen verpacken einer mehrzahl von fläschchen oder einer mehrzahl von fläschchenverschlüssen. |
DE102013114896A1 (de) * | 2013-12-27 | 2015-07-02 | Schott Ag | Verpackungsstruktur und Verfahren zur sterilen Verpackung von Behältern für Substanzen für medizinische, pharmazeutische oder kosmetische Anwendungen sowie Verfahren zur Weiterverarbeitung von Behältern unter Verwendung der Verpackungsstruktur |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE202011051492U1 (de) * | 2011-09-30 | 2011-12-20 | Wiebold-Confiserie Gmbh & Co. Kg | Pralinenverpackung |
US11161633B2 (en) | 2017-12-22 | 2021-11-02 | West Pharmaceutical Services, Inc. | Packaging system for aseptic filling of small volume vials |
USD937408S1 (en) * | 2020-07-03 | 2021-11-30 | Novandi Chemistry AB | Container to transport chemical substances |
CA3237705A1 (en) * | 2021-11-11 | 2023-05-19 | Austin Medical Ventures, Inc. | Devices and systems for preparing therapeutic pellets |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3601350A1 (de) * | 1986-01-18 | 1987-07-23 | Bachmann Horst | Vorrichtung und verfahren zur verpackung von feinmechanischen und/oder elektronischen bauteilen |
US6212858B1 (en) * | 1994-08-23 | 2001-04-10 | Alusuisse Technology & Management Ltd. | Process for manufacturing blister packs |
WO2002046060A1 (de) * | 2000-12-06 | 2002-06-13 | Ebewe Pharma Ges.M.B.H. Nfg.Kg | Transportverpackung für flaschen |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3503493A (en) * | 1968-01-08 | 1970-03-31 | Hoffmann La Roche | Medicament packaging device |
US3603453A (en) * | 1969-06-09 | 1971-09-07 | Parke Davis & Co | Pharmacal package construction |
CA1097233A (en) * | 1977-07-20 | 1981-03-10 | George K. E. Gregory | Packages |
GB2101094B (en) * | 1981-07-07 | 1984-10-24 | Cito Pac Verpackungs Gmbh | Blister pack strip |
GB8525498D0 (en) * | 1985-10-16 | 1985-11-20 | Scient Applied Research Sar | Container for eggs |
US5244092A (en) * | 1989-12-06 | 1993-09-14 | Canon Kabushiki Kaisha | Package for ink jet cartridge |
US5302358A (en) * | 1993-01-15 | 1994-04-12 | H. W. Andersen Products, Inc. | Sterilizing apparatus |
AR029768A1 (es) * | 1999-10-18 | 2003-07-16 | Novartis Ag | Paquete de plastico para un producto farmaceutico y metodo para fabricar y esterilizar un paquete farmaceutico |
US6588180B2 (en) * | 2001-02-02 | 2003-07-08 | R. P. Scherer Technologies, Inc. | Constricted neck blister pack and apparatus and method for making the same |
US7431171B2 (en) * | 2006-09-11 | 2008-10-07 | Lamarche Paul | Two piece container incorporating nesting characteristics and including interengageable hinge supports for upwardly supporting a lid upon a base |
-
2006
- 2006-12-04 AT AT0200906A patent/AT504573B1/de not_active IP Right Cessation
-
2007
- 2007-12-04 US US12/517,548 patent/US20100155271A1/en not_active Abandoned
- 2007-12-04 EP EP07845276A patent/EP2121473A2/de active Pending
- 2007-12-04 CA CA2707532A patent/CA2707532A1/en not_active Abandoned
- 2007-12-04 AU AU2007329159A patent/AU2007329159A1/en not_active Abandoned
- 2007-12-04 WO PCT/AT2007/000545 patent/WO2008067576A2/de active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3601350A1 (de) * | 1986-01-18 | 1987-07-23 | Bachmann Horst | Vorrichtung und verfahren zur verpackung von feinmechanischen und/oder elektronischen bauteilen |
US6212858B1 (en) * | 1994-08-23 | 2001-04-10 | Alusuisse Technology & Management Ltd. | Process for manufacturing blister packs |
WO2002046060A1 (de) * | 2000-12-06 | 2002-06-13 | Ebewe Pharma Ges.M.B.H. Nfg.Kg | Transportverpackung für flaschen |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH702668A1 (de) * | 2010-02-04 | 2011-08-15 | Christian Schuetz | Setverpackung zum sterilen verpacken einer mehrzahl von fläschchen oder einer mehrzahl von fläschchenverschlüssen. |
DE102013114896A1 (de) * | 2013-12-27 | 2015-07-02 | Schott Ag | Verpackungsstruktur und Verfahren zur sterilen Verpackung von Behältern für Substanzen für medizinische, pharmazeutische oder kosmetische Anwendungen sowie Verfahren zur Weiterverarbeitung von Behältern unter Verwendung der Verpackungsstruktur |
DE102013114896B4 (de) * | 2013-12-27 | 2015-08-27 | Schott Ag | Verpackungsstruktur und Verfahren zur sterilen Verpackung von Behältern für Substanzen für medizinische, pharmazeutische oder kosmetische Anwendungen sowie Verfahren zur Weiterverarbeitung von Behältern unter Verwendung der Verpackungsstruktur |
US9598195B2 (en) | 2013-12-27 | 2017-03-21 | Schott Ag | Packaging structure and method for sterile packaging containers for substances for medical, pharmaceutical or cosmetic applications and methods for further processing of containers using this packaging structure |
Also Published As
Publication number | Publication date |
---|---|
WO2008067576A3 (de) | 2008-10-09 |
AT504573A1 (de) | 2008-06-15 |
AT504573B1 (de) | 2010-09-15 |
US20100155271A1 (en) | 2010-06-24 |
AU2007329159A1 (en) | 2008-06-12 |
CA2707532A1 (en) | 2008-06-12 |
EP2121473A2 (de) | 2009-11-25 |
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