WO2008066038A1 - Procédé d'utilisation d'un produit cosmétique et produit cosmétique - Google Patents

Procédé d'utilisation d'un produit cosmétique et produit cosmétique Download PDF

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Publication number
WO2008066038A1
WO2008066038A1 PCT/JP2007/072857 JP2007072857W WO2008066038A1 WO 2008066038 A1 WO2008066038 A1 WO 2008066038A1 JP 2007072857 W JP2007072857 W JP 2007072857W WO 2008066038 A1 WO2008066038 A1 WO 2008066038A1
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WIPO (PCT)
Prior art keywords
cosmetic
effect
hair
evaluation
minutes
Prior art date
Application number
PCT/JP2007/072857
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English (en)
Japanese (ja)
Inventor
Masahiko Komoto
Satoshi Nishimura
Original Assignee
Naris Cosmetics Co., Ltd.
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Filing date
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Application filed by Naris Cosmetics Co., Ltd. filed Critical Naris Cosmetics Co., Ltd.
Publication of WO2008066038A1 publication Critical patent/WO2008066038A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/90—Block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Definitions

  • the present invention relates to a method for using cosmetics, and more particularly, to a method for applying cosmetics, and cosmetics such as skin care cosmetics.
  • Skin care cosmetics such as lotions, creams, and emulsions are cosmetics that are applied directly to the skin (skin) of the human body. After applying skin care cosmetics, makeup cosmetics are applied as necessary.
  • the white jellyfish polysaccharide extracted from the fruit body of white jellyfish is useful as a skin care cosmetic since it has an excellent moisturizing effect.
  • Patent Document 1 Japanese Patent No. 2969365
  • Patent Document 2 JP-A-2005-330257
  • Patent Document 1 can improve and improve the basic and essential functions of the cosmetics-properties, , Regarding the effect of improving the transparency and the hair-growth effect, the immediate effect is insufficient, and it is difficult to check these effects remarkably.
  • the white jellyfish polysaccharide is highly soluble in water, so it only dissolves in the water-soluble polymers exemplified above, and when it is prepared as an oily cosmetic such as make-up cosmetic, it does not dissolve or disperse uniformly. A malfunction occurs. Further, when the white jellyfish polysaccharide is used after being treated with ultrafine particles, the dispersibility is improved and the function as a dynamic polymer is reduced. Moreover, the white jellyfish polysaccharide does not dissolve in a hydrophobic solvent as it is, so that it is still difficult to prepare it as an oily cosmetic.
  • the object of the present invention is excellent in immediate effect, skin firmness improvement effect, wrinkle improvement effect, lift-up effect, skin transparency improvement effect, skin moisturizing effect, whitening effect (skin color improvement effect), Hair growth effect (hair thickness improvement effect), hair gloss improvement effect, pore improvement effect, skin texture improvement effect, acne improvement effect, and anti-inflammatory effect can be remarkably confirmed It is to provide a method for using cosmetics.
  • Another object of the present invention is that it can be prepared as an oily cosmetic while retaining the moisturizing effect expressed by the white jellyfish polysaccharide, and further, improves wrinkles after pressurization and moisturizes. It is to provide a cosmetic that can further improve the effect.
  • the method of using the cosmetic composition of the present invention comprises a cosmetic composition of 50 to 190M.
  • It is characterized by applying pressure treatment for 15 minutes or more with Pa, and applying the cosmetic after pressure treatment to the skin or hair within 8 hours after the pressure treatment.
  • the cosmetic is heated to 10 to 50 ° C. in the pressure treatment.
  • the cosmetic of the present invention is characterized by a white jellyfish polysaccharide and polio.
  • the cosmetic of the present invention is preferably subjected to a pressure treatment at 50 to 190 MPa for 15 minutes or more,
  • the cosmetic is pressure-treated at 50 to 190 MPa for 15 minutes or more. Then, the pressure-treated cosmetics improve skin firmness, wrinkle improvement effect, lift-up effect, skin transparency improvement effect, skin moisturizing effect, whitening effect, hair growth effect, hair gloss improvement It becomes an active state capable of imparting effects, pore improvement effect, skin texture improvement effect, double acne improvement effect, and anti-inflammatory effect.
  • the cosmetic is then applied to the skin or hair within 8 hours after the pressure treatment. Then, the applied cosmetic penetrates into the skin or hair while maintaining the active state. For this reason, the skin or hair is infused with active cosmetics to improve skin wrinkles, lift-up effect, transparency improvement effect, whitening effect, hair growth effect, anti-inflammatory effect, anti-acne effect, etc. Since the various effects described above appear immediately, these effects can be confirmed remarkably.
  • the cosmetic of the present invention can be prepared as an oily cosmetic while maintaining the moisturizing effect expressed by the white jellyfish polysaccharide. Furthermore, according to the cosmetics of the present invention, wrinkle improvement effect after pressure treatment, moisturizing effect, elasticity improvement effect, lift-up effect, pore improvement effect, skin texture improvement effect, transparency improvement Effects, hair growth effects, and hair shine improvement effects can be obtained.
  • FIG. 1 is an image processing diagram in the vicinity of a head shot taken in Evaluation Test Example 4.
  • FIG. 2 is an image processing diagram showing the three-dimensional curved surface shape of the face measured in Evaluation Test Example 4.
  • FIG. 3 (a) to (c) are image processing diagrams of optical micrographs of damaged hair photographed for sensory evaluation of the degree of improvement in hair thickness with V and deviation.
  • FIG. 4 An image processing diagram of a photograph in the vicinity of the eyes taken for evaluation of the improvement of wrinkles!
  • FIG. 5 is an image processing diagram of a half-face photograph taken in the evaluation of the improvement degree of pores.
  • FIG. 6 is an image processing diagram of a half-face photograph taken in the evaluation of the improvement in texture.
  • FIG. 7 (a) and (b) are image processing diagrams of a sample photograph taken in turbidity measurement.
  • the cosmetic is pressure-treated at 50 to 190 MPa for 15 minutes or more.
  • the cosmetic does not include a semi-finished cosmetic product in the middle of manufacture, but includes only a finished cosmetic product after manufacture.
  • the cosmetic of the present invention is intended for the pressure treatment of a finished cosmetic product after production, which is not related to the presence or absence of the pressure treatment during the production.
  • Examples of such cosmetics include skin care cosmetics that are applied directly to the skin of a human body (including the face and body) to give the skin a smooth, moist feeling. included.
  • Examples of skin care cosmetics include facial cleansing foams, lotions, creams, milky lotions, jewels, massages, beauty liquids (essences), lotions, knocks, sunscreens, and Siebin Grossions.
  • the cosmetics of the present invention are mainly applied to the scalp for the purpose of hair cosmetics to be applied to hair such as tonics, shampoos, rinses and hair creams, hair loss prevention and hair growth promotion, for example, hair growth.
  • Hair-growth cosmetics such as hair and hair-care agents, and hair dyes such as hair colors and hair manicures, and cosmetics containing powders such as liquid foundation and cream foundation are also included.
  • the cosmetic used in the method of using the cosmetic of the present invention is not particularly limited, but various dosage forms such as liquid, cream, jelly, emulsion, sol and gel are available. Can be appropriately selected.
  • the cosmetic is in a form capable of measuring the average particle diameter, such as powder, slurry, emulsion (including micelles), and dispersion, the average before pressure treatment is used.
  • the particle diameter is preferably, for example, 0.;! To 10 m, and further 1 to 5 m as the median diameter.
  • the median diameter can be measured by, for example, a laser diffraction / scattering type particle size distribution measuring apparatus.
  • the above-described cosmetic has a viscosity (26 ° C) before pressure treatment of, for example, 0.1 to 50 Pa's (26 ° C), or 0.5 to 30 Pa-s ( 26 ° C) is preferred. Viscosity can be measured with a B-type viscometer (Brookfield viscometer) at 26 ° C.
  • the cosmetic used in the method of using the cosmetic of the present invention contains a high molecular compound capable of imparting elasticity such as, for example, white jellyfish polysaccharide, carboxybule polymer, agar, collagen, and the like! /, The power S is suitable. If such a polymer compound is contained! /, The wrinkle improvement and the lift-up effect can be further improved. Note that the blending ratio of such a polymer compound is, for example, 0.001 to;% by weight with respect to the total amount of the cosmetic.
  • the pressure treatment of the cosmetic is not particularly limited, and a known press method such as a direct pressure press method or an isotropic pressure press method may be used according to the dosage form or the treatment amount. Is possible.
  • a known press method such as a direct pressure press method or an isotropic pressure press method
  • an isotropic pressure pressing method CIP
  • an isostatic pressing method can be used.
  • a CIP method such as a hydrostatic pressure press method
  • a flexible bag such as a heat seal bag
  • the functional bag is put into a pressure medium tank of a known isotropic pressure press machine (for example, a water tank of an isostatic press machine) and then pressed.
  • the cosmetic is applied at 50 to 190 MPa, preferably 70 to 150 MPa, more preferably 85 to 125 MPa for 15 minutes or more, preferably 20 minutes or more, usually 60.
  • the pressure is increased for 15 to 60 minutes, preferably 20 to 60 minutes, more preferably 25 to 50 minutes, and then returned to normal pressure.
  • the pressure is less than the lower limit or when the time is shorter than the lower limit, it is difficult to obtain sufficient effects of the present invention on the skin and hair because the average particle size of the cosmetic is too large. It becomes.
  • the pressure exceeds the above upper limit the average particle size of the cosmetic (when the average particle size can be measured, the same applies hereinafter) becomes too small. It becomes difficult to obtain an immediate effect.
  • the upper limit of the time is preferably 60 minutes from the economical viewpoint.
  • the cosmetic is preferably heated to 10 to 50 ° C, more preferably 30 to 50 ° C, and particularly preferably 30 to 40 ° C.
  • the pressure treatment if the cosmetic is heated in the above temperature range, the immediate effect of the excellent effect of the present invention described later is improved. That's the power S. If the cosmetic is heated at a temperature exceeding the above upper limit, the cosmetic condition may change, making it unsuitable for use.
  • the heating is performed, for example, by installing a heater such as a jacket heater on a known press machine (such as the above-described hydrostatic press machine) so that the temperature of the cosmetic is within the above temperature range. Set the heating temperature in the heater.
  • a heater such as a jacket heater
  • a known press machine such as the above-described hydrostatic press machine
  • the above cosmetics can improve the wrinkles, lift-up effect, transparency improvement effect, hair growth effect, anti-inflammatory effect, anti-acne effect, whitening effect, etc. It will be in the active state which can provide the effect of.
  • the active state is a state in which a cluster of water molecules and component particles that have changed due to the pressure treatment can develop a self-restoring force to restore the state before the pressure treatment.
  • the cosmetic after pressure treatment has an average particle size and viscosity that are reduced compared to the cosmetic before pressure treatment.
  • the cosmetic of the present invention has an average particle size of
  • the average particle diameter (median diameter) before the pressure treatment is, for example,;! ⁇ 80% smaller, preferably 10-50% smaller. More specifically, as the media diameter, if it is arranged, it will be in the form of 0.0
  • the viscosity (26 ° C) of the cosmetic material after the pressure treatment is, for example, 5 to 50% lower, preferably 10 to 30% lower. More specifically, for example, 0.5 to 5 Pa ′ s (26 ° C.) and 1 to 3 Pa ′ s (26 ° C.).
  • the cosmetic of the present invention gradually increases to an average particle diameter (median diameter) or viscosity before pressure treatment by self-restoring force immediately after application to the skin or hair. Restores (or changes more than that) to give the skin and hair firmness (tension, elasticity), thereby improving wrinkles, lift-up effect, transparency improvement effect, whitening effect.
  • the above-mentioned various effects such as hair-growth effect, anti-inflammatory effect, and anti-acne effect can be imparted.
  • the cosmetic after the pressure treatment is applied to the skin within 8 hours, preferably within 3 hours, more preferably within 1 hour after the pressure treatment. Or apply to hair.
  • the active state of the cosmetic of the present invention will disappear.
  • the cosmetic of the present invention is applied to the skin or hair, it is restored to the state before the pressure treatment (or the state where the active state disappears more than that), and the excellent It becomes difficult to obtain an effect.
  • the skin to which the cosmetic is applied is not particularly limited, and may be any part of the human skin.
  • the cosmetic after the pressure treatment may be applied to the skin by a method of normally applying the cosmetic.
  • the cosmetic after the pressure treatment is peeled off. Apply directly to the skin.
  • the amount of application is not particularly limited, and if it is for one person, it is, for example, about 0.;! To 2 g although it depends on the size of the face.
  • the hair to which the cosmetic is applied is not particularly limited, but is mainly scalp hair.
  • the cosmetic after pressure treatment is usually applied to the cosmetic.
  • the cosmetic after pressure treatment is applied directly to the hair.
  • an emulsion in an activated state is in a state where the average particle diameter is gradually increased in viscosity. Then, the skin or hair swells due to the self-restoring power of the cosmetics, and is given a skin and hair.
  • skin Effects such as lift-up effect, transparency improvement effect that improves skin transparency by improving moisture retention, hair growth effect that enhances hair growth and promotes hair growth, rough skin after shaving (redness Anti-inflammatory effect that protects skin from troubles such as itchiness).
  • Such an effect is manifested immediately after the cosmetic is applied to the skin or hair, and thereafter, after the cosmetic is maintained for a certain period of time in the active state described above, the active state of the cosmetic is When disappearing, the above effect disappears. More specifically, the above effect is manifested, for example, within 3 hours immediately after the cosmetic is applied to the skin or hair, and the duration of the effect is, for example, about 2 weeks at the longest. .
  • the cosmetic of the present invention comprises a white jellyfish polysaccharide, polyoxybutylene polyoxyethylene,
  • a white jellyfish polysaccharide is obtained by extracting a fruit body of a white jellyfish using water and / or a water-soluble solvent (for example, alcohols such as ethanol and propanol, and darikols such as ethylene glycol and propylene glycol) as an extraction solvent. You can get power S.
  • a water-soluble solvent for example, alcohols such as ethanol and propanol, and darikols such as ethylene glycol and propylene glycol
  • Shiroki Fuku (Shiraki;) ⁇ , 'Tremella mciiormis' is a mushroom belonging to the genus Shiroki Fuku genus, whose fruit body is jelly, shrinks when dry and revenges when wet.
  • the extraction method is not particularly limited, and a known method is used.
  • 0.1 to 30 parts by weight of a white jellyfish fruit body is immersed in 100 parts by weight of the extraction solvent and extracted at room temperature to 100 ° C. for 0.5 to 24 hours. Thereafter, the white jellyfish polysaccharide is obtained by filtration or centrifugation.
  • the white jellyfish polysaccharide thus obtained is a natural plant polysaccharide (natural plant polymer) having mannose in the main chain and xylose and glucuronic acid in the side chain. It is an acidic heteropolysaccharide containing at least% by weight. Its average molecular weight is approximately 1 million or more.
  • Such a white jellyfish polysaccharide is commercially available, and such a commercially available product can also be used.
  • Examples of commercially available products include “Tremoyist-TP” (manufactured by Nippon Seika Co., Ltd.).
  • alkylene oxide derivative of glycerin specifically, polyoxypropylene, polyoxyethylene and polyoxybutylene force S, block copolymerization or random copolymerization with glyceryl ether.
  • polyoxypropylene, polyoxyethylene and polyoxybutylene are block-copolymerized in that order with glyceryl ether.
  • propylene oxide, ethylene oxide and It can be obtained by sequential addition polymerization of butylene oxide.
  • the ratio of each component is, for example, 2 to 8 mol parts of polyoxypropylene (propylene oxide) and 5 to 11 mol of polyoxyethylene (ethylene oxide) per 1 mol part of glyceryl ether (glycerin).
  • polyoxybutylene (butylene oxide) The average molecular weight (GPC method; standard polystyrene conversion) is, for example, 500 to 1400, preferably 776 to 1124. It is marketed and such a commercial item can also be used.
  • Examples of commercially available products include “WILBRIDE (R) S-753” (manufactured by NOF Corporation). For example, from! To 200 parts by weight, preferably from 10 to 100 parts by weight, based on 100 parts by weight of the white jellyfish polysaccharide.
  • the cosmetic of the present invention can be formulated into various dosage forms such as liquid, cream, jelly, emulsion, sol and gel.
  • various dosage forms such as liquid, cream, jelly, emulsion, sol and gel.
  • different power depending on the dosage form for example, a white jellyfish polysaccharide and a polyoxygenous component are blended in a water-soluble solvent.
  • water-soluble solvent examples include water, for example, alcohols such as ethanol, propanol, and isopropanol. These may be used alone or in combination.
  • hydropower S is used.
  • the blending ratio of each component varies depending on the dosage form. For example, for 100 parts by weight of the water-soluble solvent, for example, 0.000;! To 1 part by weight, preferably 0.01 to 0.2.
  • the ether is, for example, 0.;! To 20 parts by weight, preferably; !! to 10 parts by weight.
  • the cosmetic of the present invention can be blended with other moisturizing agents for improving the moisturizing property within a range that does not impair the excellent effects of the present invention.
  • humectants include, for example, nonionic water-soluble polymers (eg, polyethylene glycol Nore, polyethylene oxide, copolymers of ethylene oxide and propylene oxide, etc.), anionic water-soluble polymers (eg, hyaluronic acid, xanthan gum, chondroitin sulfate, polyglutamic acid, polyaspartic acid, carboxymethyl cellulose), phosphorus Lipid (for example, phosphatidylcholine, phosphatidylethanolamine, phosphatidinoreserin, phosphatidinoreinositole, soy lecithin, egg yolk lecithin, castor lecithin, etc.), ceramide, polyhydric alcohol, monosaccharide, amino acids, betaine, urea, natural extract, Vitamin
  • additives can be blended within a range that does not inhibit the excellent effects of the present invention.
  • additives include surfactants, antioxidants, UV absorbers, preservatives, bactericides, chelating agents, pH adjusters, exfoliating agents, anti-inflammatory agents, refreshing agents, and fragrances. Is mentioned.
  • the blending ratio of such additive is appropriately selected.
  • the cosmetic of the present invention contains a white jellyfish polysaccharide and polyoxybutylene polyoxyethylene polyoxypropylene glyceryl ether.
  • various cosmetics such as aqueous cosmetics and oily cosmetics are compatible. be able to. Therefore, for example, the cosmetic of the present invention can be prepared as an oily cosmetic even though it contains a white jellyfish polysaccharide. Can exhibit excellent moisturizing effect
  • the cosmetics of the present invention include, for example, facial cleansing foams, lotions, creams, milky lotions, gels, massages, beauty liquids (essences), lotions, knocks, sunscreens, shaving lotions, etc.
  • Skin care cosmetics such as tonics, shampoos, rinses, hair creams, etc., hair cosmetics applied to hair such as tonics, shampoos, rinses, hair creams, etc.
  • Hair growth and hair nourishing cosmetics applied to the scalp of hair such as hair coloring, hair manicure and other hair coloring, such as lipstick, lip gloss, teak, concealer, foundation, mascara, eyeliner, eye shadow, deodorant Makeup cosmetics such as sunscreens and hair tics, It can be widely prepared as an oily cosmetic.
  • the cosmetic of the present invention is applied to the skin or hair after the pressure treatment, the effect of improving wrinkles, moisturizing effect, improving elasticity, lift-up effect, improving pores, improving transparency Improving effect, hair-growth effect, and hair shine improvement effect can be expressed immediately.
  • the method for applying the cosmetic of the present invention to the skin or hair after pressure treatment will be described in detail.
  • the cosmetic of the present invention is pressure-treated at 50 to 190 MPa for 15 minutes or more, and the cosmetic after pressure treatment is applied to the skin or hair within 8 hours after the pressure treatment.
  • the cosmetic of the present invention is in a form capable of measuring the average particle diameter, such as powder, slurry, emulsion (including micelles), and dispersion.
  • the average particle size before the pressure treatment is preferably 0.;! To lO ⁇ m, more preferably 1 to 5 m as a median size.
  • the median diameter can be measured by, for example, a laser diffraction / scattering particle size distribution measuring apparatus.
  • the cosmetic composition of the present invention has a viscosity (26 ° C) before pressure treatment, for example, 0.1 to 50 Pa's (26 ° C), and further 0.5 to 30 Pa's (26 ° C). C) is preferred. Viscosity can be measured with a B-type viscometer (Brookfield viscometer) at 26 ° C.
  • the pressure treatment of the cosmetic is not particularly limited, and a known press method such as a direct pressure press method or an isotropic pressure press method may be used depending on the dosage form, the treatment amount, and the like. Is possible.
  • a known press method such as a direct pressure press method or an isotropic pressure press method may be used depending on the dosage form, the treatment amount, and the like.
  • an isotropic press method more preferably an isostatic press method can be used.
  • the specific method of the pressure treatment by the hydrostatic pressure press method is the same as described above.
  • the cosmetic is applied at 50 to 190 MPa, preferably 70 to 150 MPa, more preferably 85 to 125 MPa for 15 minutes or more, preferably 20 minutes or more, usually 60 minutes or less.
  • pressurize for 15 to 60 minutes, preferably 20 to 60 minutes, more preferably 25 to 50 minutes, and then return to normal pressure. If the pressure or pressurization time during the pressurization process is out of the above range, the same problem as described above will occur.
  • the cosmetic is preferably heated to 10 to 50 ° C, more preferably 30 to 50 ° C, and particularly preferably 30 to 40 ° C. Effects obtained when the temperature during pressure treatment is set in the above range, problems that occur when the lower limit is not reached, and The pressure treatment method is the same as described above.
  • the cosmetic of the present invention is in an active state capable of imparting the above-described various effects such as wrinkle improvement, lift-up effect, transparency improvement effect, hair growth effect and the like.
  • the active state is as described above.
  • the average particle diameter after the pressure treatment of the cosmetic of the present invention is reduced with respect to the cosmetic before the pressure treatment.
  • the cosmetic of the present invention has an average particle diameter of
  • the average particle diameter (median diameter) before pressurization is, for example,! ⁇ 80% smaller, preferably 10-50% smaller More specifically, the median diameter is in the form of ⁇ circle around (0.0) ⁇ ; 10 111;
  • the viscosity (26 ° C) of the cosmetic after the pressure treatment is, for example, 5 to 50% lower, preferably 10 to 30% lower, and more specifically, for example, 0.5 to 5 Pa 's (26 ° C), and !! to 3 Pa' s (26 ° C).
  • the cosmetic after the pressure treatment is applied to the skin or hair within 8 hours, preferably within 3 hours, more preferably within 1 hour after the pressure treatment.
  • the troubles that occur when not applied within the above time are the same as described above.
  • the application method and application amount to the skin, and the application method to the hair are all the same as described above.
  • the cosmetic of the present invention maintains the above-mentioned activated state while maintaining the above-mentioned activated state. Penetration into the skin and the inside of the hair or restoration to the state before the pressure treatment (or more changes). For example, an emulsion in an activated state is in a state where the average particle size gradually increases in viscosity. Then, the skin or hair swells due to the self-restoring power of the cosmetic, and is added with water and skin.
  • the effect of improving skin wrinkles such as stretching of the hair wrinkles and the skin elasticity are improved (the skin is improved).
  • Effect for example, lift-up effect, transparency improvement effect that improves skin transparency by improving moisture retention, hair growth effect that promotes hair growth while adding gloss to hair, rough skin after shaving (redness, itching, etc.
  • the anti-inflammatory effect that protects the skin from troubles) is expressed.
  • Such an effect is manifested immediately after the cosmetic is applied to the skin or hair, and then, after the cosmetic is maintained for a certain period of time in the active state described above, the active state of the cosmetic is When disappearing, the above effect disappears. More specifically, the above effect is manifested, for example, within 3 hours immediately after the cosmetic is applied to the skin or hair, and the duration of the effect is, for example, about 2 weeks at the longest. .
  • the mixture b was added to the mixture a and emulsified, and the emulsified particles were made uniform with a homomixer (hereinafter referred to as the mixture A). Further, potassium hydroxide previously dissolved in a part of purified water was added to the mixture A, stirred uniformly, and ⁇ -aminocaproic acid was added during cooling to obtain an emulsion.
  • Evaluation Test Example 1 and Evaluation Test Examples 2 and 3 to be described later sensory evaluation was performed on the degree of improvement in skin firmness and the degree of improvement in skin wrinkles.
  • the evaluation of each panelist is “best” (score: +3), “good” (score: +2), “slightly good” (score: +1), “no change” for each evaluation item. ”(Score: ⁇ 0),“ slightly bad ”(score: 1),“ bad ”(score: 2) and“ worst ”(score: 3).
  • Table 2 shows the number of panelists who made the evaluation for each evaluation level. Also, taking into account the level of evaluation and the number of panelists who performed the evaluation, we comprehensively judged whether there was any effect on the evaluation items. The method for determining the presence or absence of this effect was the same in the following evaluation test examples 2 and 3.
  • Each sample consisting of the emulsion of Formulation Example 1 was set so that the temperature of the emulsion was 32 ° C., and pressurized at a pressure of 90 MPa for 30 minutes. After 15 minutes from the end of the pressurization process, apply the sample to the face of one paneler, and before the application and after each application, 1 hour, 3 hours and 5 hours, I took a photo of the neighborhood. The results are shown in Fig. 1. [0060] Also, at the same time as taking a picture near the eyes, before use (before application), after 1 hour of use (after 1 hour of application), and after 24 hours of use (after 24 hours of application), Each three-dimensional curved surface shape was measured.
  • Each sample consisting of the emulsion of Formulation Example 1 was set so that the temperature of the emulsion was 32 ° C., and pressurized at a pressure of 90 MPa for 30 minutes.
  • the average particle size and viscosity of the emulsion were measured before pressing and after 15 minutes, 1 hour, 2 hours, 3 hours and 24 hours from the end of the pressing process.
  • the temperature of the emulsion at the time of viscosity measurement was 26 ° C. The results are shown in Table 5.
  • a sample prepared by diluting an emulsion with distilled water to 0.5% by weight was used.
  • the average particle size is measured with a laser diffraction / scattering particle size distribution measuring instrument “LA-920 type” (manufactured by Horiba, Ltd.), and both the transmittance of laser light and tungsten light is measured in the sample measurement section.
  • the amount was set to 70 to 95%, and the measurement was started after the transmittance was stabilized.
  • the measurement result was a median diameter.
  • a sample was obtained in the same manner as the pressure treatment of Evaluation Test Example 1 except that the face washing foam A2g of Formulation Example 2 was used in place of the emulsion 2g of Formulation Example 1.
  • each sample consisting of the face-washing foam A of Formulation Example 2 was set so that the temperature force of the face-washing foam A was 3 ⁇ 42 ° C, and was pressurized at a pressure of 90 MPa for 30 minutes.
  • facial cleansing form A was applied to the face of each panel, and an evaluation test was performed. The same sensory evaluation as in Test Example 1 was performed.
  • mixture c 1,3-butylene glycol, glycerin, and aloe extract were added to purified water and dissolved.
  • mixture d squalene, PO E (20) sorbitan monolaurate, POE (15) lauryl alcohol ether, tocopherol acetate, paraben, and fragrance were added to ethanol and dissolved (hereinafter referred to as mixture d).
  • mixture d was added to the mixture c and solubilized to obtain a lotion.
  • a sample was obtained in the same manner as the pressure treatment of Evaluation Test Example 1 except that 2 g of the skin lotion of Formulation Example 3 was used instead of 2 g of the emulsion of Formulation Example 1.
  • each sample made of the skin lotion of Formulation Example 3 was set so that the temperature of the skin lotion was 32 ° C., and was pressurized for 30 minutes at a pressure of 90 MPa. Next, after 15 minutes from the end of the pressure treatment, lotion was applied to the face of each paneler, and the same sensory evaluation as in Evaluation Test Example 1 was performed. It was used for.
  • the mixture f was added to the mixture e for emulsification, the emulsified particles were homogenized with a homomixer, and collagen (0.1 wt% aqueous solution) was added during cooling to obtain cream A.
  • a sample was obtained in the same manner as in the pressure treatment of Evaluation Test Example 1 except that 2 g of the cream A of Formulation Example 4 was used instead of 2 g of the emulsion of Formulation Example 1.
  • each sample consisting of the cream of Formulation Example 4 was set so that the temperature of the cream was 32 ° C., and was pressurized for 30 minutes at a pressure of 90 MPa.
  • the pressurizing treatment After 15 minutes from the end of the pressurizing treatment, it was applied to the face of each paneler and subjected to the same sensory evaluation as in Evaluation Test Example 1.
  • carboxybulbomer was added to purified water and dissolved uniformly (hereinafter referred to as mixture g).
  • mixture g dipropylene glycol, PEG 1500, POE (15) oleyl alcohol ether, paraben, and tocopherol acetate were added to the mixture g to make it uniform (hereinafter referred to as mixture h).
  • mixture i potassium hydroxide previously dissolved in purified water was added to the mixture h, and the mixture was uniformly stirred and neutralized (hereinafter referred to as mixture i). Then, mix i in advance. Diels were obtained by adding hyaluronic acid that was uniformly dissolved in water to make it uniform.
  • Evaluation test example 9 pressing treatment and evaluation of jewel
  • a sample was obtained in the same manner as the pressure treatment of Evaluation Test Example 1 except that 2 g of Giel of Formulation Example 5 was used instead of 2 g of the emulsion of Formulation Example 1.
  • each sample consisting of the jewels of Formulation Example 5 was subjected to pressure treatment at a pressure of 90 MPa for 30 minutes while setting the temperature of the jewels to be 32 ° C. After 15 minutes from the end of the pressure treatment, it was applied to the face of each paneler and subjected to the same sensory evaluation as in Evaluation Test Example 1.
  • mixture j and To do sorbitol, 1,3-butylene glycol, ⁇ G 1500, hyaluronic acid and quince seed were added to purified water and dissolved uniformly (hereinafter referred to as mixture j and To do).
  • mixture k POE oleyl alcohol ether, olive oil, tocopherol acetate and paraben were added to ethanol and dissolved uniformly (hereinafter referred to as mixture k). Subsequently, the mixture k was added to the mixture j and mixed uniformly to obtain a cosmetic liquid A.
  • a sample was obtained in the same manner as the pressure treatment of Evaluation Test Example 1 except that the cosmetic liquid A2g of Formulation Example 6 was used instead of the emulsion 2g of Formulation Example 1.
  • each sample consisting of the cosmetic liquid A of Formulation Example 6 was set so that the temperature of the cosmetic liquid A was 32 ° C., and was pressurized for 30 minutes at a pressure of 90 MPa. After 15 minutes from the end of the pressurizing treatment, it was applied to the face of each paneler and subjected to the same sensory evaluation as in Evaluation Test Example 1.
  • a sample was obtained in the same manner as the pressure treatment of Evaluation Test Example 1, except that the hair cream A2g of Formulation Example 7 was used instead of the emulsion 2g of Formulation Example 1.
  • a sample consisting of hair cream A of Formulation Example 7 was set so that the temperature of hair cream A was 32 ° C., and pressure-treated at a pressure of 90 MPa for 30 minutes. After 15 minutes from the end of the pressurization treatment, it was applied to the hair of each paneler and subjected to sensory evaluation.
  • glycerin, assembly extract, vitamin ⁇ 6, tocopherol acetate, ⁇ (20) sorbitan monolaurate and fragrance are added to ethanol and dissolved, and then purified water is added to dissolve and hair growth Agent was obtained.
  • a sample was obtained in the same manner as in the pressure treatment of Evaluation Test Example 1 except that the hair restorer A2 g of Formulation Example 8 was used instead of 2 g of the emulsion of Formulation Example 1.
  • the sample comprising the hair restorer A of Formulation Example 8 was set so that the temperature of the hair restorer A was 32 ° C, and was pressurized for 30 minutes at a pressure of 90 MPa. After 15 minutes from the end of the pressurization treatment, it was applied to the scalp of each paneler and subjected to sensory evaluation. As a result, all of them improved the gloss of hair and the effect of promoting hair growth.
  • a sample was obtained in the same manner as the pressure treatment of Evaluation Test Example 1 except that the cosmetic liquid B2g of Formulation Example 9 was used in place of the emulsion 2g of Formulation Example 1.
  • each sample consisting of the cosmetic liquid B of Formulation Example 9 was subjected to pressure treatment under the following conditions (i) to (iii).
  • the treatment time was fixed at 30 minutes, the treatment temperature was fixed at 32 ° C, and the treatment pressure was set at 40, 50, 90, 150, 190 and 200 MPa.
  • the treatment pressure was fixed at 90 MPa, the treatment temperature was fixed at 32 ° C, and the treatment time was set to 10 minutes, 15 minutes, 30 minutes, 60 minutes and 24 hours.
  • the processing pressure is fixed at 90 MPa, the processing time is fixed at 30 minutes, and the processing temperatures are 25, 28, 30, 35, 40, 45, 50 and 55. Each temperature of C was set.
  • the lift-up effect was evaluated in the same manner as in Evaluation Test Example 4 by taking a photograph of the vicinity of each paneler's head and measuring the three-dimensional curved surface shape as described above.
  • the contour line force around the eyes is observed to see if it is denser than before applying the serum, and to what extent the change is, and “improvement” (+2), “slightly improvement” (+ 1), “No change” ( ⁇ 0), “Slightly worse” (—1), and “Deteriorated” (1 2).
  • the scores of the five panelists were totaled to comprehensively evaluate the lift-up effect.
  • the overall evaluation criteria are “no effect” when the total score is less than 10% of the full score (10 points), 10% or more “Slightly effective” when less than 40%, “effective” when 40% or more and less than 80%, and “very effective” when 80% or more.
  • the evaluation results are shown in Tables 14 to 16:
  • Evaluation test example 13 (1) (ii): Pressurization treatment and evaluation of essence B (formulation example 9): Change over time> Treatment pressure: 90 MPa. Treatment temperature: 323 ⁇ 4
  • the lift-up effect is extremely effective when the pressure of the pressure treatment is 50 190 MPa. If the pressure is outside the above range, the lift-up effect will be slightly reduced. I got it. From Table 15 and Table 16, the lift-up effect is extremely effective when the processing time force for pressure treatment is 3 ⁇ 40 minutes or more, and extremely effective when the processing temperature is 2850 ° C. I found out that
  • Evaluation test example 13 (2) (i): Pressurization treatment and evaluation of serum B (formulation example 9): Pressure change> Treatment time: 30 minutes, Treatment temperature: 323 ⁇ 4
  • Damaged hair thickness (mm) 0.085 0.090 0.095 0.095 0.095 0.085 0.085 0.080 Increase after treatment (mm) 0.005 0.010 0.015 0.015 0.015 0.005 0.005 ⁇
  • Damaged hair thickness (mm) 0.085 0.090 0.095 0.095 0.095 0.085 0.080 Increase after treatment (mm) 0.005 0.010 0.015 0.015 0.015 0.005 ⁇ Slightly effective Extremely extremely slightly effective Yes Active Effective Effective Effective
  • FIG. 3 (a) images of damaged hair taken with an optical microscope are shown in Figs. 3 (a) to 3 (c).
  • Fig. 3 (a) All images shown in Fig. 3 (c) have the same magnification.
  • the diameter of the damaged hair is 0.080 mm when the serum is not applied (Fig. 3 (a)), and when the serum is applied without pressure treatment (Fig. 3 (b)).
  • 0.085 mm when applying a cosmetic liquid that has been subjected to pressure treatment (treatment pressure 90 MPa, treatment temperature 32 ° C, treatment time 30 minutes) (Fig. 3 (c)), At once.
  • the overall evaluation criteria are “no effect” if the total score is less than 10% of the full score (15 points), “somewhat effective” if the total score is 10% or more and less than 40%, 40% or more When it was less than 80%, “effective”, and when it was 80% or more, “very effective”.
  • the evaluation results are shown in Tables 20-22.
  • Evaluation test example 13 (3) (i): Pressurization and evaluation of serum B (formulation example 9): Pressure change> Processing time: 30 minutes. Processing temperature: 32 ° C
  • Evaluation test example 13 (3) (ii): Pressurization treatment and evaluation of essence B (Prescription Example 9): Change over time> Treatment pressure: 90 MPa, Treatment temperature: 323 ⁇ 4 Treatment time Pressure treatment
  • the effect of improving hair shine is effective when the pressure of the pressure treatment is 50 to 190 MPa, and if it is outside the above range, the degree of improvement of hair shine is slightly higher. The power that can be lowered has been reduced.
  • Table 21 and Table 22 show that the effect of improving hair gloss is effective when the treatment time is 15 minutes or more, and is effective when the treatment temperature is 30 50 ° C. Power, ivy.
  • the overall evaluation criteria are “no effect” when the total score (50 points) of 5 panelists is less than 10%, and when the score is 10% or more and less than 40% “Slightly effective”, “effective” when 40% or more and less than 80%, and “very effective” when 80% or more.
  • the results are shown in Tables 23-25.
  • Evaluation test example 13 (4) (i): Pressurization treatment and evaluation of serum B (Prescription Example 9): Pressure change> Treatment time: 30 minutes, Treatment temperature: 32 ° C
  • Paneler 1 1 6 10 8 10 2 Paneler 2 0 7 7 10 9 1 Paneler 3 4 4 10 9 8 1 Paneler 4 4 7 10 9 10 1 Paneler 5 5 7 10 10 10 0 Total score 14/50 31/50 47 / 50 46/50 47/50 5/50 Comprehensive evaluation Somewhat effective Effective Very effective Very effective Very effective Somewhat effective
  • the comparison of skin texture was conducted by five specialist referees.
  • the skin texture was “improved” (+2), “slightly improved” (+1), “no change” ( ⁇ 0) , “Slightly worsened” (1) and “Deteriorated” (1 2) were evaluated in 5 grades (the score in Katsuko is rated).
  • the scores of the five panelists were totaled, and the scores obtained by each paneler were added together to comprehensively evaluate the effect of improving skin texture.
  • the overall evaluation criteria are “No effect” when the total score of the five panelists is less than 10% of the full score (50 points), “Slightly effective” when the total score is 10% or more and less than 40%. ”,“ Effective ”when 40% or more and less than 80%, and“ Very effective ”when 80% or more.
  • Tables 26-28 The results are shown in Tables 26-28.
  • Evaluation test example 13 (5) (i): Pressurization treatment and evaluation of serum B (formulation example 9): Pressure change> Treatment time: 30 minutes, Treatment temperature: 32 D C
  • Evaluation test example 13 (5) (ii): Pressurization treatment and evaluation of essence B (Prescription example 9): Change over time> Treatment pressure: 90 MPa, Treatment temperature: 323 ⁇ 4 Treatment time Pressure treatment
  • the conditions of the pressure treatment were any of those shown in (i) to (iii) of Evaluation Test Example 13 Even if the conditions are the same, the force with a certain degree of improvement in the degree of improvement in skin transparency, the treatment pressure force S50 ⁇ 190MPa, the treatment time is 15 minutes or more, the treatment temperature When the temperature was 30 ° C or higher and 50 ° C or lower, the degree of improvement in skin transparency was extremely good.
  • component numbers;! To 5 are mixed and dissolved by heating, 80. Adjusted to C.
  • the component numbers 6 to 12 are mixed and dissolved by heating, 80. While adjusting to C, add the mixture of component numbers;! ⁇ 5 to this and emulsify, then 50 with stirring. Cooled to C. Then mix ingredient number 13 while adjusting the mixture to 50 ° C. A whitening emulsion was prepared by stirring and cooling to C.
  • a sample was obtained in the same manner as in the pressure treatment of Evaluation Test Example 1 except that 2 g of the whitening emulsion of Formulation Example 10 was used instead of 2 g of the emulsion of Formulation Example 1.
  • each sample consisting of the whitening emulsion of Prescription Example 10 was subjected to pressure treatment under the following conditions (i) to (iii).
  • the treatment time was fixed at 30 minutes, the treatment temperature was fixed at 32 ° C, and the treatment pressure was set at 40, 50, 90, 150, 190 and 200 MPa.
  • the treatment pressure was fixed at 90 MPa, the treatment temperature was fixed at 32 ° C, and the treatment time was set to 10 minutes, 15 minutes, 30 minutes, 60 minutes and 24 hours.
  • the processing pressure is fixed at 90 MPa, the processing time is fixed at 30 minutes, and the processing temperatures are 9, 10, 20, 30, 40, 45, 50 and 55, respectively. Each temperature of C was set.
  • the whitening effect (degree of improvement in skin color) is effective when the pressure of the pressure treatment is 50 MPa or more, and when it exceeds 190 MPa, the degree of whitening may be slightly reduced.
  • the whitening effect (improvement level of skin color) is effective when the processing time is 15 minutes or more and effective when the processing temperature is 10 50 C from Table 31 and Table 32. I was strong.
  • a sample was obtained in the same manner as the pressure treatment of Evaluation Test Example 1 except that the cosmetic liquid C2g of Formulation Example 11 was used instead of the emulsion 2g of Formulation Example 1.
  • each sample comprising the cosmetic liquid C of Prescription Example 11 was subjected to pressure treatment under the following conditions (i) to (iii).
  • the treatment time was fixed at 30 minutes, the treatment temperature was fixed at 32 ° C, and the treatment pressure was set at 40, 50, 90, 150, 190 and 200 MPa.
  • the treatment pressure was fixed at 90 MPa, the treatment temperature was fixed at 32 ° C, and the treatment time was set to 10 minutes, 15 minutes, 30 minutes, 60 minutes and 24 hours.
  • the processing pressure is fixed at 90 MPa, the processing time is fixed at 30 minutes, and the processing temperatures are 9, 10, 20, 30, 40, 45, 50 and 55, respectively. Each temperature of C was set.
  • serum C apply pressure treatment to the left face, apply pressure treatment to the right face, and observe and contrast the left and right faces during sensory evaluation. .
  • Evaluation criteria for improvement of acne are “significantly effective” when the acne disappears (+3), and “effective” when the acne is significantly reduced compared to the beginning (+3). + 2), “Slightly effective” (+1) when wrinkles were reduced compared to the start, and “No change” ( ⁇ 0) when there was no change compared to the start.
  • the amount of millet is slightly increased compared to the beginning, it is “slightly worse” (1), and when the amount of double is increased compared to the beginning, it is “deteriorated” (1).
  • the number of acne was significantly increased, it was rated as “significantly worse” (1), and was rated on a 7-point scale (the score in Katsuko is rated).
  • the scores of 15 panelists who were self-scored were totaled, and the improvement effect of acne was comprehensively evaluated.
  • the overall evaluation standard is that the total score is less than 10% of the full score (45 points). ⁇ No effect '' when full, ⁇ Slightly effective '' when 10% or more and less than 40%, 40
  • the improvement effect of acne is effective when the pressure of the pressure treatment is 50 to 190MPa, and the degree of improvement effect of acne is slightly lower if the above range is exceeded. To become a power, I got. Also, according to Table 35 and Table 36, the improvement effect of acne is effective when the processing time is 15 minutes or more, and is extremely effective when the processing temperature is 20 to 50 ° C. I understood.
  • component numbers 1 to 5 were mixed, dissolved by heating, and adjusted to 80 ° C.
  • component Nos. 6 to 12 were mixed, dissolved by heating, adjusted to 80 ° C, emulsified by adding the mixture of component Nos. 1 to 5, and then stirred up to 50 ° C. Cooled down. Thereafter, while adjusting the mixture to 50 ° C, Component No. 13 was mixed, stirred to 40 ° C and cooled to obtain an anti-inflammatory emulsion.
  • Evaluation Test Example 16 Pressure treatment and evaluation of anti-inflammatory emulsion
  • a sample was obtained in the same manner as the pressure treatment of Evaluation Test Example 1 except that 2 g of the anti-inflammatory emulsion of Formulation Example 12 was used instead of 2 g of the emulsion of Formulation Example 1.
  • each sample comprising the anti-inflammatory emulsion of Prescription Example 12 was subjected to pressure treatment under the following conditions (i) to (iii).
  • the treatment time was fixed at 30 minutes, the treatment temperature was fixed at 32 ° C, and the treatment pressure was set at 40, 50, 90, 150, 190 and 200 MPa.
  • the treatment pressure was fixed at 90 MPa, the treatment temperature was fixed at 32 ° C, and the treatment time was set to 10 minutes, 15 minutes, 30 minutes, 60 minutes and 24 hours.
  • the processing pressure is fixed at 90 MPa, the processing time is fixed at 30 minutes, and the processing temperatures are 9, 10, 20, 30, 40, 45, 50 and 55, respectively. Each temperature of C was set.
  • Panels consisted of 10 men with sensitive skin shaving with a razor every day, and each paneler used anti-inflammatory latex after shaving with a razor, and then 30 minutes after shaving. The state of the face (redness and itchiness) was observed, and sensory evaluation of the anti-inflammatory effect (improvement of the inflammatory state) was performed.
  • the anti-inflammatory emulsion is applied to the left face with the pressure treatment applied, and applied to the right face with the non-pressure treatment applied, and the left and right faces are observed during sensory evaluation. Contrast.
  • the evaluation was based on anti-inflammatory effects: “significantly effective” (+3), “effective” (+2), “somewhat effective” (+1), “no change” ( ⁇ 0), In addition, the evaluation was made on a five-point scale (rating in Katsuko): “Deterioration” (—1). In addition, the scores from the self-scoring of 10 panelists were totaled to comprehensively evaluate the effect of improving the inflammatory condition.
  • the overall evaluation criteria are “No effect” when the total score is less than 10% of the full score (60 points), “Slightly effective” when the total score is 10% or more and less than 40%, 40 “Effective” when the percentage is above 80% and below 80%, and “very effective” when the percentage is above 80%.
  • Example 1 and Comparative Example 13 were formulated. Specifically, first, component numbers 1 to 12 were mixed, dissolved by heating, and adjusted to 70 ° C. Separately, component number 13 was mixed with component number 13, dissolved by heating, and adjusted to 70 ° C. Thereafter, the mixture of component numbers;! To 12 and the mixture of component numbers 13 to 15 were mixed, emulsified with a homomixer, and then cooled to prepare a cream.
  • each of cream B from Formulation Example 13 is placed in a small-capacity heat-sealed bag (Uniback A-4, manufactured by Nihonsha Co., Ltd.), degassed, and then heat-sealed (Desktop vacuum sealer for business use SQ-202, Sharp Sealing was performed using
  • the sealed small-capacity heat seal bag is put together into the large-capacity heat paper bag (Uniback F—4, manufactured by Production Japan Co., Ltd.) for the number of times of measurement in each evaluation test example to be described later. The same as above) was used to seal a large-capacity heat seal bag, which was used as a sample.
  • design pressure max. 100MPa
  • design temperature max. 75 ° C
  • body material SUS630
  • set the cream temperature to 32 ° C
  • the cream BO.02g of the prescription example 13 was uniformly applied to the inside part of the upper arm of a healthy male at 2 cm ⁇ 2 cm square.
  • SKICON-200 type skin surface moisture measuring device after 10 minutes, 20 minutes, 30 minutes, 1 hour, 4 hours and 24 hours from application
  • the amount of water (unit: 11 S (micro Siemens)) was measured. The results are shown in Table 42. The moisture content is measured five times for each measurement item and shown as the average value.
  • Cosmetic liquid D of Example 2 and Comparative Example 45 was prepared using the above-mentioned formulation. Specifically, first, component number 36 was mixed and heated to 80 ° C. to dissolve the mixture. on the other hand Ingredient Nos. 1, 2 and 7-; 12 were mixed and heated to 80 ° C. to dissolve the mixture. Next, the mixture of component numbers 3 to 6 was mixed with the mixture of component numbers 1, 2 and 7 to 12 and stirred at high speed for 1 minute with a homomixer, and then air-cooled to 60 ° C with slow stirring. . Thereafter, Component No. 13 was mixed, and water-cooled to 35 ° C with slow stirring to prepare Beauty Liquid D.
  • a sample was obtained in the same manner as the pressure treatment of Evaluation Test Example 17 except that the cosmetic liquid D2g of Formulation Example 14 was used instead of Cream B2g of Formulation Example 13.
  • each sample consisting of the cosmetic liquid D of Prescription Example 14 was set so that the temperature of the cosmetic liquid D was 32 ° C., and pressurized at a pressure of 90 MPa for 30 minutes.
  • Panelists were five healthy women in their 40s and 60s. In each panel, wash the face with a commercially available face wash foam, wipe off the moisture with a towel, and then apply DOG 2g of Prescription Example 14 uniformly on one half face, and the other half face The sample was left uncoated until the next day. The next day, the condition of the skin was observed, and the sensory evaluation was performed for the degree of improvement of the elasticity and the lift-up effect. In the sensory evaluation, the skin condition before and after the test was compared and scored based on the following evaluation criteria. The results are shown in Table 44.
  • Panelists were five healthy women in their 40s and 60s. In each panel, wash the face with a commercially available face wash foam, wipe off the moisture with a towel, and then apply DOG 2g of Prescription Example 14 uniformly on one half face, and the other half face The sample was left uncoated until the next day. And the state of the skin was evaluated the next day. In the evaluation, a microscope (Char m Lite Stand III: Moritex Co., Ltd.) was used to photograph pores and textures, and beauty. The state before and after application
  • a face-wash foam wrinkle was prepared in the above-mentioned formulation. Specifically, first, component numbers 1 to 9 are mixed and dissolved by heating. Adjusted to C. Separately, component number 11 was dissolved in component number 10, and the mixture of component numbers 1 to 9 was added to the mixture while stirring to neutralize it. After completion of the neutralization reaction, the face washing foam B was prepared by further adding component numbers 12 to 14 and cooling with stirring.
  • Hair cream B was prepared in the above formulation. Specifically, the ingredients Nos. 1 to 9 are mixed and dissolved by heating. Adjusted to C. Separately, add component numbers 11 to 13 to component number 10 and dissolve by heating. Adjusted to C. Then, the mixture of component numbers 1 to 13 was added to the mixture of component numbers 10 to 13 and emulsified, and the emulsified particles were unified with a homomixer. After that, add component number 14 dissolved in component number 10 to this, Cooled with uniform stirring, and then added ingredient number 15 to prepare hair cream B o
  • Hair restorer B was prepared in the above formulation. Specifically, component number 1 8 was mixed and dissolved by heating, and then dissolved in component number 10 and component number 10 Ingredient No. 9 was added and dissolved uniformly to prepare hair restorer B
  • Example 3 and Comparative Examples 6 to 12 cosmetic liquid E was prepared. Specifically, first, components No .:! To 16 were dissolved by heating and kept at 80C. Add the ingredient No. 18 25 to the ingredient No. 17 and dissolve it by heating. ⁇ ; After the mixture of 16 was added and emulsified, the emulsified particles were made uniform while stirring with a homomixer. Next, the emulsion was cooled to 50 ° C., the component No. 26 was added, and the mixture was stirred and cooled to 40 ° C., thereby preparing cosmetic liquid E.
  • each sample consisting of the cosmetic liquid E of Formulation Example 18 was set so that the temperature of the cosmetic liquid E was 32 ° C., and was pressurized for 30 minutes at a pressure of 90 MPa.
  • Panelists were five healthy women in their 40s and 50s. In each panel, the face was washed with a commercially available face-washing foam, and the moisture was wiped off with a towel. Then, the cosmetic liquid E0.2 of prescription example 18 was applied to either the left or right face, and nothing was applied to the other face and left until the next day. The next day, each paneler's facial skin condition was observed, and sensory evaluations were made regarding the improvement of wrinkles, the improvement of the skin, the improvement of lift and the lift-up effect. In the sensory evaluation, the skin condition before and after the test was compared and scored based on the following evaluation criteria.
  • test was carried out on both the above samples that had been subjected to pressure treatment (hydrostatic pressure press) (after 15 minutes from the end of the caloric pressure treatment) and those that had not been subjected to pressure treatment.
  • Table 56 shows the results of the improvement of the seeds
  • Table 57 shows the results of the improvement of (2) and (2)
  • Table 58 shows the results of the lift-up effect.
  • Paneler 1 5 4 4 4 4 3 3 3 Paneler 2 4 4 4 3 3 2 2 2 Paneler 3 5 4 4 4 3 3 2 2 2 Paneler 4 4 3 3 3 3 2 2 2 Paneler 5 4 4 3 3 2 2 3 2 Total score 22/25 19/25 18/25 17/25 15/25 12/25 12/25 11/25
  • Paneler 1 5 4 5 4 4 4 3 3 Paneler 2 5 4 4 3 4 3 Paneler 3 5 4 4 4 3 4 4 3 Paneler 4 5 4 4 4 4 3 3 Paneler 5 5 4 4 3 4 3 4 4 4 4 4 Total score 25/25 20/25 21/25 18/25 19/25 17/25 18/25 16/25
  • Example 3 From Table 56 58, in the cosmetic liquid of Example 3 containing both the white jellyfish polysaccharide (white jellyfish extract) and wilbright (polyoxy,, 'chille, polyoxyethylene polyoxypropylene glyceryl ether), There were many testers who felt a higher effect regarding the improvement of the elasticity and the lift-up effect. In addition, this tendency became even more prominent by applying pressure treatment to the serum. On the other hand, the comparative essence containing either white jellyfish extract and wilbright has improved wrinkle improvement, firmness improvement and Regarding the toe-up effect, the subject felt a slight effect. However, in the comparative essence that did not contain both white jellyfish extract and wilbright, no improvement was observed in the wrinkles, firmness and lift-up effect.
  • white jellyfish polysaccharide white jellyfish extract
  • wilbright polyoxy,, 'chille, polyoxyethylene polyoxypropylene glyceryl ether
  • the serum EO.02g of Prescription Example 18 was uniformly applied to the inside part of the upper arm of a healthy male at 2cm x 2cm square. After application, 10 minutes, 20 minutes, 30 minutes, 1 hour, 4 hours and 24 hours, the skin surface horn layer moisture content measuring device SKICON-200 (made by IBS Co., Ltd.) The water content (unit: a S (micro Siemens)) was measured. The results are shown in Table 59. The moisture content is measured five times for each measurement item and shown as the average value.
  • Example 3 The essence of Example 3 containing both extract and wilbright (polyoxybutylene polyskin ethyl ester) was moisturized regardless of whether or not it was pressurized. The effect was high. On the other hand, a white fungus extract, in the serums of Comparative Examples 6 to 1 2 does not include either one or both of the Will Bright, sufficient moisturizing effect is not obtained.
  • Example 3 The cosmetic liquid of Example 3 containing both (oxyethylene polyoxypropylene glyceryl ether) was highly effective in improving pores and texture regardless of the presence or absence of pressure treatment.
  • the cosmetic solution of the comparative example containing either white jellyfish extract or wilbright the subject felt a slight effect for improving pores and texture.
  • comparison without both white jellyfish extract and wilbright The cosmetic liquid of the example did not improve pores or texture.
  • Panelists were five healthy women in their 30s and 60s. In each panel, the face was washed with a commercially available face-washing foam, the moisture was wiped off with a towel, and then 2 g of essence liquid EO. Furthermore, at 6 hours after application, the transparency (L value) of each panel was measured. In the measurement of transparency, a spectrocolorimeter CD100 (manufactured by Yokogawa M & C Co., Ltd.) was used, and the L value of the part where the spots were not noticeable on the starboard of each panel was measured. The measured value was obtained by measuring the L value at the same location as before coating with the above spectrocolorimeter and subtracting the L value before coating from the L value 6 hours after coating.
  • a spectrocolorimeter CD100 manufactured by Yokogawa M & C Co., Ltd.
  • FIGS. 3 (a) to 3 (C) The diameter of the damaged hair is 0.080 mm when the cosmetic liquid (Cosmetic liquid B of prescription example 9 or cosmetic liquid E of prescription example 18) is not applied (Fig. 3 (a)).
  • a cosmetic liquid that has not been subjected to pressure treatment was applied (Fig. 3 (b))
  • it was 0.085mm and was subjected to pressure treatment treatment pressure 90MPa, treatment temperature 32 ° C, treatment time 30 minutes.
  • treatment pressure 90MPa treatment temperature 32 ° C, treatment time 30 minutes
  • the cosmetic liquid When the cosmetic liquid was applied ( Figure 3 (c)), it was 0.095 mm.
  • the overall evaluation criteria are “no effect” when the total score is less than 10% of the full score (15 points), “somewhat effective” when the total score is 10% or more and less than 40%, 40% or more When it was less than 80%, it was “effective”, and when it was 80% or more, it was “very effective”.
  • the evaluation results are shown in Table 64 and Table 65.
  • Nikkor BC Instead of 20TX (polyoxyethylene cetyl ether (20 ⁇ ⁇ ⁇ .)), Nikkorole PBC34 (polyoxyethylene (5) polyoxypropylene (8) cetinoreate nore) 5.00 parts by weight Except for the above, a cosmetic was prepared in the same manner as Comparative Sample 1 (this was referred to as Comparative Sample 2).
  • a cosmetic was prepared in the same manner as Comparative Sample 1 except that 00 parts by weight was added (this is referred to as Sample 1).
  • the absorbance of the specimen at a wavelength of 650 nm was measured with a spectrophotometer (manufactured by Shimadzu Corporation, UV-2450), and turbidity was measured.
  • a spectrophotometer manufactured by Shimadzu Corporation, UV-2450
  • turbidity 100 an aqueous suspension in which kuto soil (manufactured by Wako Pure Chemical Industries, Ltd.) was dispersed at a concentration of 100 mg / L was designated as turbidity 100.
  • the water suspension was diluted and the absorbance was measured, and a calibration curve showing the relationship between absorbance and turbidity was prepared.
  • the turbidity of the beauty solution of each sample is a value calculated based on the calibration curve. The turbidity indicates that the closer the value is to 0, the higher the transparency.
  • Fig. 7 (a) the above measurement results show that the turbidity of sample 1 (35 degrees) is determined by placing the cosmetic of sample 1 in a transparent container. Change the thickness (thickness) to 5cm When the bottom of the container was visually observed from the top of the cosmetic, the numbers printed on the bottom of the container (size: 11 points, font: century) were easily visible.
  • the turbidity of comparative sample 1 (185 degrees) and the turbidity of comparative sample 2 (225 degrees) The numbers were completely unreadable.
  • the white jellyfish polysaccharide can be dissolved in both an aqueous medium and an oily medium by coexisting with polyoxybutylene polyoxyethylene polyoxypropylene glyceryl ether. Tsutsu.
  • Example 3 in Formulation Example 18 and the cosmetic liquid E2g in Comparative Examples 6-9 and 12 were used in the same manner as the pressure treatment in Evaluation Test Example 17 Got a sampnore.
  • each sample consisting of Example 3 and Comparative Examples 6 to 9 and 12 was set so that the temperature of the cosmetic liquid E would be 32 ° C, and 90 MPa The pressure was applied for 30 minutes.
  • the average particle size of serum B was measured before pressurization and after the lapse of 15 minutes, 1 hour, 2 hours, 3 hours, 4 hours, 8 hours and 24 hours from the end of the pressure treatment. The results are shown in Table 66 and Table 67.
  • the average particle size For the measurement of the average particle size, a sample prepared by diluting cosmetic liquid E with distilled water to 0.5% by weight was used. The average particle size is measured with a laser diffraction / scattering type particle size distribution measuring instrument “LA-920 type” (manufactured by Horiba, Ltd.). The amount was set to 70 to 95%, and the measurement was started after the transparency was stabilized. The measurement result was a median diameter.
  • the cosmetic liquid E2g of Example 3 is put into a small-capacity heat seal bag (UNIPACK A-4, manufactured by Nippon Nihonsha), deaerated, and then heat sealed (desktop vacuum sealer for business use) SQ-202, manufactured by Sharp Corporation) was used for sealing.
  • the sealed small-capacity heat-seal bag is packed into the large-capacity heat-seal bag (Yunipak F-4, manufactured by Nihon Shokuhin Co., Ltd.) for the number of measurements, and using the heat-seal device A large-capacity heat seal bag was sealed and used as a sample.
  • the average particle size of serum E was measured before pressurization and after 15 minutes, 1 hour, 2 hours, 3 hours, 4 hours, 8 hours and 24 hours from the end of the pressure treatment.
  • the method for measuring the average particle size is the same as the method for measuring the average particle size in Evaluation Test 21 (1).
  • the measurement results are shown in Table 68 and Table 69.
  • Evaluation test example 21 (2) Evaluation of Example 3 of serum E (formulation example 18)> Processing time: 30 minutes, processing temperature 323 ⁇ 4
  • the method of using the cosmetic composition of the present invention is suitable as a skin care cosmetic composition for obtaining effects such as wrinkle improvement, lift-up effect, transparency enhancement effect, hair growth effect, anti-inflammatory effect and the like. is there.
  • the cosmetic of the present invention is suitable, for example, as an oily cosmetic that retains the moisturizing effect expressed by the white jellyfish polysaccharide, specifically, as a makeup cosmetic or a skin care cosmetic containing the white jellyfish polysaccharide. It is.
  • the cosmetic of the present invention is a skin care cosmetic for obtaining effects such as wrinkle improvement, lift-up effect, transparency improvement effect, hair growth effect, anti-inflammatory effect, etc., through a predetermined pressure treatment. Is preferred.

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  • Health & Medical Sciences (AREA)
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Abstract

L'invention porte sur un procédé d'utilisation d'un produit cosmétique procurant un excellent effet immédiat et est capable de confirmer de manière significative un effet tel qu'une amélioration des rides, un effet de redrapage du visage et du cou, une amélioration de la netteté, une croissance capillaire ou une anti-inflammation ; et sur un produit cosmétique pouvant être préparé sous la forme d'un produit cosmétique à base huileuse, tout en maintenant un effet hydratant présenté par un polysaccharide de champignon oreille de bois blanc et pouvant en outre présenter l'effet ci-dessus après un traitement de pression. Le procédé consistant à utiliser un cosmétique de l'invention comprend les opérations consistant à soumettre un produit cosmétique à un traitement de pression à 50 à 190 MPa pendant 15 minutes ou plus tout en chauffant, et à appliquer le produit cosmétique après le traitement de pression sur la peau ou les cheveux en l'espace de 8 heures après le traitement de pression. En outre, le produit cosmétique de l'invention est préparé par mélange d'un polysaccharide de champignon oreille de bois blanc avec un polyoxybutylène polyoxyéthylène polyoxypropylène glycéryl éther.
PCT/JP2007/072857 2006-11-27 2007-11-27 Procédé d'utilisation d'un produit cosmétique et produit cosmétique WO2008066038A1 (fr)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010006715A (ja) * 2008-06-24 2010-01-14 L'oreal Sa 美白用外用剤、水溶性美白成分の皮膚浸透促進剤、及び、皮膚美白方法
JP2011032273A (ja) * 2009-08-04 2011-02-17 L'oreal Sa オキシアルキレン化誘導体を含む化粧品組成物
JP2014237708A (ja) * 2014-08-15 2014-12-18 ロレアル 美白用外用剤、水溶性美白成分の皮膚浸透促進剤、及び、皮膚美白方法
JP2015514777A (ja) * 2012-04-19 2015-05-21 ザ プロクター アンド ギャンブルカンパニー 化粧品組成物
JP2016132626A (ja) * 2015-01-16 2016-07-25 株式会社マンダム 拭き取り用ニキビ予防ローション
CN113425663A (zh) * 2021-08-18 2021-09-24 皖西学院 一种石斛花大豆美肤面膜的制备方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110604698B (zh) * 2019-07-04 2022-06-21 上海辉文生物技术股份有限公司 一种以银耳为基材的膜布的制备方法及其应用

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Publication number Priority date Publication date Assignee Title
JPH0426611A (ja) * 1990-05-17 1992-01-29 Narisu Keshohin:Kk 化粧料
JP2002518422A (ja) * 1998-06-23 2002-06-25 タルク・ド・リュズナック 疎水性の鉱物粉を主成分とする取扱可能な固形製品
JP2006131558A (ja) * 2004-11-05 2006-05-25 Nippon Menaade Keshohin Kk コラーゲン生成促進剤

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0426611A (ja) * 1990-05-17 1992-01-29 Narisu Keshohin:Kk 化粧料
JP2002518422A (ja) * 1998-06-23 2002-06-25 タルク・ド・リュズナック 疎水性の鉱物粉を主成分とする取扱可能な固形製品
JP2006131558A (ja) * 2004-11-05 2006-05-25 Nippon Menaade Keshohin Kk コラーゲン生成促進剤

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010006715A (ja) * 2008-06-24 2010-01-14 L'oreal Sa 美白用外用剤、水溶性美白成分の皮膚浸透促進剤、及び、皮膚美白方法
JP2011032273A (ja) * 2009-08-04 2011-02-17 L'oreal Sa オキシアルキレン化誘導体を含む化粧品組成物
JP2015514777A (ja) * 2012-04-19 2015-05-21 ザ プロクター アンド ギャンブルカンパニー 化粧品組成物
JP2014237708A (ja) * 2014-08-15 2014-12-18 ロレアル 美白用外用剤、水溶性美白成分の皮膚浸透促進剤、及び、皮膚美白方法
JP2016132626A (ja) * 2015-01-16 2016-07-25 株式会社マンダム 拭き取り用ニキビ予防ローション
CN113425663A (zh) * 2021-08-18 2021-09-24 皖西学院 一种石斛花大豆美肤面膜的制备方法

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