WO2007124698A3 - Métodos para tratar la infección por flavivirus, moléculas y usos - Google Patents
Métodos para tratar la infección por flavivirus, moléculas y usos Download PDFInfo
- Publication number
- WO2007124698A3 WO2007124698A3 PCT/CU2007/000014 CU2007000014W WO2007124698A3 WO 2007124698 A3 WO2007124698 A3 WO 2007124698A3 CU 2007000014 W CU2007000014 W CU 2007000014W WO 2007124698 A3 WO2007124698 A3 WO 2007124698A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- molecules
- treatment
- methods
- receptor
- flavivirus infection
- Prior art date
Links
- 206010054261 Flavivirus infection Diseases 0.000 title 1
- 102000014914 Carrier Proteins Human genes 0.000 abstract 2
- 108010078791 Carrier Proteins Proteins 0.000 abstract 2
- 102100021923 Prolow-density lipoprotein receptor-related protein 1 Human genes 0.000 abstract 2
- 108020003175 receptors Proteins 0.000 abstract 2
- 102000005962 receptors Human genes 0.000 abstract 2
- 206010012310 Dengue fever Diseases 0.000 abstract 1
- 101000799972 Homo sapiens Alpha-2-macroglobulin Proteins 0.000 abstract 1
- 101001043564 Homo sapiens Prolow-density lipoprotein receptor-related protein 1 Proteins 0.000 abstract 1
- 101710172064 Low-density lipoprotein receptor-related protein Proteins 0.000 abstract 1
- 108010003533 Viral Envelope Proteins Proteins 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 208000025729 dengue disease Diseases 0.000 abstract 1
- 102000049437 human A2M Human genes 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 230000002452 interceptive effect Effects 0.000 abstract 1
- 101150084157 lrp-1 gene Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
- C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07721810.5A EP2022506B1 (en) | 2006-04-28 | 2007-04-26 | Method for the treatment of flavivirus infection, molecules and uses thereof |
ES07721810.5T ES2645679T3 (es) | 2006-04-28 | 2007-04-26 | Método para el tratamiento de infección por flavivirus, moléculas y sus usos |
CA2650591A CA2650591C (en) | 2006-04-28 | 2007-04-26 | Methods for the treatment of flavivirus infection, molecules and uses thereof |
CN2007800224852A CN101472606B (zh) | 2006-04-28 | 2007-04-26 | 用于治疗黄病毒感染的方法、分子及用途 |
AU2007246076A AU2007246076B2 (en) | 2006-04-28 | 2007-04-26 | Methods for the treatment of flavivirus infection, molecules and uses thereof |
US12/298,808 US8420311B2 (en) | 2006-04-28 | 2007-04-26 | Method to block the infection by flaviviruses, molecules and uses |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CU20060091A CU23632A1 (es) | 2006-04-28 | 2006-04-28 | Métodos para la identificación de candidatos terapéuticos contra enfermedades causadas por flavivirus y moléculas antivirales. |
CU2006-0091 | 2006-04-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007124698A2 WO2007124698A2 (es) | 2007-11-08 |
WO2007124698A3 true WO2007124698A3 (es) | 2007-12-27 |
Family
ID=38476089
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CU2007/000014 WO2007124698A2 (es) | 2006-04-28 | 2007-04-26 | Métodos para tratar la infección por flavivirus, moléculas y usos |
Country Status (11)
Country | Link |
---|---|
US (1) | US8420311B2 (es) |
EP (1) | EP2022506B1 (es) |
CN (1) | CN101472606B (es) |
AR (1) | AR060827A1 (es) |
AU (1) | AU2007246076B2 (es) |
CA (1) | CA2650591C (es) |
CU (1) | CU23632A1 (es) |
ES (1) | ES2645679T3 (es) |
MY (1) | MY150685A (es) |
RU (1) | RU2008146997A (es) |
WO (1) | WO2007124698A2 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CU23245A1 (es) | 2001-07-16 | 2007-10-17 | Inst De Medicina Tropical Pedr | CADENAS QUIMéRICAS CODIFICANTES PARA PROTEINAS INDUCTORAS DE EFECTOS CONTRA VIRUS. PREPARADOS UTILIZANDO PROTEINAS QUIMéRICAS |
CU23578A1 (es) | 2005-09-16 | 2010-09-30 | Ct Ingenieria Genetica Biotech | Proteína de la cápsida del virus dengue inductora de respuesta protectora y composición vacunal |
CU23630A1 (es) | 2006-10-30 | 2011-02-24 | Ct Ingenieria Genetica Biotech | Moléculas peptídicas quiméricas con propiedades antivirales contra los virus de la familia flaviviridae |
CU20080028A6 (es) | 2008-02-29 | 2011-02-24 | Ct Ingenieria Genetica Biotech | Compuestos químicos obtenidos in silico para la preparación de composiciones farmacéuticas para atenuar o inhibir la infección por virus dengue y otros flavivirus |
WO2013126587A1 (en) | 2012-02-21 | 2013-08-29 | Cytonics Corporation | Systems, compositions, and methods for transplantation |
AU2013299986B2 (en) * | 2012-08-07 | 2018-05-17 | Massachusetts Institute Of Technology | Anti-dengue virus antibodies and uses thereof |
US10442868B2 (en) | 2013-03-14 | 2019-10-15 | Rhode Island Hospital, A Lifespan-Partner | Treating hepatitis B virus infections by administering receptor associated protein (RAP) |
SG11201606624WA (en) | 2014-02-11 | 2016-09-29 | Visterra Inc | Antibody moleules to dengue virus and uses thereof |
CA2938495A1 (en) | 2014-02-11 | 2015-08-20 | Massachusetts Institute Of Technology | Full spectrum anti-dengue antibody |
CU20140026A7 (es) * | 2014-03-03 | 2015-11-27 | Ct De Ingeniería Genética Y Biotecnología Biocubafarma | Péptidos horquilla beta con propiedades antivirales contra el virus dengue |
CA3018216A1 (en) | 2016-03-25 | 2017-09-28 | Visterra, Inc. | Formulations of antibody molecules to dengue virus |
JP2019523633A (ja) * | 2016-04-29 | 2019-08-29 | アライム ファーマシューティカルズ,インコーポレーテッド | 組織の損傷に関連した疾患及び障害を予防及び治療する組織保護ペプチド |
CN111537316A (zh) * | 2020-06-17 | 2020-08-14 | 陕西健吉跃生物科技有限公司 | 一种检测蛋白含量的氨基黑染色液、试剂盒及方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004016586A2 (en) * | 2002-08-16 | 2004-02-26 | Board Of Regents The University Of Texas System | Compositions and methods related to flavivirus envelope protein domain iii antigens |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5494671A (en) * | 1990-08-27 | 1996-02-27 | The United States Of America As Represented By The Department Of Health And Human Services | C-terminally truncated dengue and Japanese encephalitis virus envelope proteins |
US6403092B1 (en) | 1998-04-01 | 2002-06-11 | Duke University | Immune response modulator alpha-2 macroglobulin complex |
US7449321B2 (en) * | 2003-01-22 | 2008-11-11 | National University Of Singapore | Molecules, compositions, methods and kits for applications associated with flaviviruses |
US7622113B2 (en) * | 2003-12-08 | 2009-11-24 | The United States Of America As Represented By The Department Of Health And Human Services | Monoclonal antibodies that bind or neutralize dengue virus |
WO2005123774A2 (en) * | 2004-06-15 | 2005-12-29 | Erol Fikrig | Antibodies to west nile virus polypeptides |
DE102006014892B4 (de) | 2005-03-31 | 2020-09-24 | Ngk Spark Plug Co., Ltd. | Gassensorelement, Verfahren zu seiner Herstellung, und Gassensor |
-
2006
- 2006-04-28 CU CU20060091A patent/CU23632A1/es unknown
-
2007
- 2007-04-26 WO PCT/CU2007/000014 patent/WO2007124698A2/es active Application Filing
- 2007-04-26 RU RU2008146997/13A patent/RU2008146997A/ru not_active Application Discontinuation
- 2007-04-26 MY MYPI20084354 patent/MY150685A/en unknown
- 2007-04-26 AU AU2007246076A patent/AU2007246076B2/en not_active Ceased
- 2007-04-26 CN CN2007800224852A patent/CN101472606B/zh active Active
- 2007-04-26 EP EP07721810.5A patent/EP2022506B1/en active Active
- 2007-04-26 ES ES07721810.5T patent/ES2645679T3/es active Active
- 2007-04-26 CA CA2650591A patent/CA2650591C/en active Active
- 2007-04-26 US US12/298,808 patent/US8420311B2/en active Active
- 2007-04-27 AR ARP070101838A patent/AR060827A1/es active IP Right Grant
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004016586A2 (en) * | 2002-08-16 | 2004-02-26 | Board Of Regents The University Of Texas System | Compositions and methods related to flavivirus envelope protein domain iii antigens |
Non-Patent Citations (6)
Title |
---|
CABRERA-HERNANDEZ A ET AL: "Mammalian dengue virus receptors", DENGUE BULLETIN 2005 INDIA, vol. 29, 2005, pages 119 - 135, XP001536276, ISSN: 1020-895X * |
DATABASE Geneseq [online] 20 May 2004 (2004-05-20), "Envelope protein domain III, SEQ ID 8.", XP002453500, retrieved from EBI accession no. GSP:ADK13688 Database accession no. ADK13688 * |
DATABASE Geneseq [online] 3 September 1992 (1992-09-03), "DEN1 E glycoprotein (373-398).", XP002453499, retrieved from EBI accession no. GSP:AAR25390 Database accession no. AAR25390 * |
DATABASE Geneseq [online] 9 March 2006 (2006-03-09), "West Nile virus envelope protein ectodomain peptide 39.", XP002453298, retrieved from EBI accession no. GSP:AEF13619 Database accession no. AEF13619 * |
KOFF W C ET AL: "INHIBITION OF DENGUE VIRUS REPLICATION BY AMANTADINE HYDRO CHLORIDE", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, DC, US, vol. 18, no. 1, July 1980 (1980-07-01), pages 125 - 129, XP009089666, ISSN: 0066-4804 * |
SCHLEGEL R ET AL: "AMANTADINE AND DANSYL CADAVERINE INHIBIT VESICULAR STOMATITIS VIRUS UPTAKE AND RECEPTOR MEDIATED ENDOCYTOSIS OF ALPHA-2 MACRO GLOBULIN", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 79, no. 7, 1982, pages 2291 - 2295, XP002453279, ISSN: 0027-8424 * |
Also Published As
Publication number | Publication date |
---|---|
CU23632A1 (es) | 2011-02-24 |
US20110212105A1 (en) | 2011-09-01 |
CN101472606B (zh) | 2012-09-19 |
CA2650591C (en) | 2014-10-07 |
AR060827A1 (es) | 2008-07-16 |
RU2008146997A (ru) | 2010-06-10 |
CA2650591A1 (en) | 2007-11-08 |
US8420311B2 (en) | 2013-04-16 |
EP2022506B1 (en) | 2017-10-11 |
WO2007124698A2 (es) | 2007-11-08 |
EP2022506A2 (en) | 2009-02-11 |
CN101472606A (zh) | 2009-07-01 |
ES2645679T3 (es) | 2017-12-07 |
MY150685A (en) | 2014-02-28 |
AU2007246076B2 (en) | 2011-06-23 |
AU2007246076A1 (en) | 2007-11-08 |
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