WO2007063648A1 - Agent attenuant les pathologies liees a l’obesite - Google Patents

Agent attenuant les pathologies liees a l’obesite Download PDF

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Publication number
WO2007063648A1
WO2007063648A1 PCT/JP2006/320476 JP2006320476W WO2007063648A1 WO 2007063648 A1 WO2007063648 A1 WO 2007063648A1 JP 2006320476 W JP2006320476 W JP 2006320476W WO 2007063648 A1 WO2007063648 A1 WO 2007063648A1
Authority
WO
WIPO (PCT)
Prior art keywords
obesity
essential oil
agent
improving
polyoxyethylene
Prior art date
Application number
PCT/JP2006/320476
Other languages
English (en)
Japanese (ja)
Inventor
Ken Harada
Chiho Motonaga
Kiyohito Sawano
Kazutoshi Sakurai
Hidetsuna Watanabe
Seiji Kawano
Original Assignee
Kose Corporation
Takasago International Corporation
Fukushima University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kose Corporation, Takasago International Corporation, Fukushima University filed Critical Kose Corporation
Priority to JP2007547866A priority Critical patent/JP5814495B2/ja
Priority to TW095144356A priority patent/TW200730185A/zh
Publication of WO2007063648A1 publication Critical patent/WO2007063648A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00—Formulations or additives for perfume preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis

Definitions

  • the present invention relates to an obesity improving agent comprising a specific essential oil or synthetic fragrance, and a skin external preparation and fragrance containing the same.
  • Mass Index Weight (kg) Z Height 2 (m)) is 25 or more.
  • a skin external preparation containing a so-called slimming agent is directly applied to human skin, a food containing a slimming agent is taken, and a body soap containing a slimming agent is used to treat the body.
  • the method of cleaning is an effective method that eliminates problems such as giving a feeling of mental pressure.
  • Specific techniques include, for example, a method of adding cognac oil or mate oil to an external preparation for skin or food (Patent Document 1), from grapefruit oil to limonate.
  • Patent Document 2 there is a method of adding modified grapefruit oil from which LOO mass% is removed to a cosmetic or food.
  • Patent Document 3 describes that one or more selected from limonene, vinylene, myrcene and benzylbenzoate, which are known as synthetic fragrances, are used as a fragrance for slimming.
  • synthetic fragrances which are known as synthetic fragrances.
  • that document only exemplifies those fragrances, and the above fragrance alone or a mixture of the above fragrances itself is not used as a fragrance for slimming in the examples.
  • the fragrance is merely exemplified as a slimming fragrance, and is only to the extent that it is unclear how effective it is as a slimming fragrance.
  • Patent Document 4 describes a cypress essential oil as an example of an activity-enhancing essential oil.
  • Patent Document 5 discloses a jelly-like food having a relaxed effect containing a herb extract as a plant extract, and Cypress essential oil is disclosed as a herb extract. There is no description that Cypress essential oil has an effect of improving obesity.
  • Patent Document 6 describes a mixture comprising lavender essential oil, rosemary essential oil or bergamot essential oil, lemon essential oil or lime essential oil, cypress essential oil or juicer essential oil, and carrier oil. The mixture is described as having an effect of improving facial contours by quickly and thoroughly removing excess fat on the facial surface.
  • lemon essential oil, rosemary essential oil, and lavender essential oil have been described to suggest fat removal, but cypress essential oil has no description to suggest such a point.
  • Patent Document 1 Japanese Patent Application Laid-Open No. 2005-68176
  • Patent Document 2 JP-A-2005-194252
  • Patent Document 3 Japanese Patent Laid-Open No. 2002-265977
  • Patent Document 4 Japanese Patent Publication No. 7-57734
  • Patent Document 5 Japanese Patent Laid-Open No. 2003-245048
  • Patent Document 6 Chinese Patent Publication No. 1247735
  • an object of the present invention is to provide an excellent agent for improving obesity state.
  • Another object of the present invention is to provide an agent for improving obesity status, which is an excellent agent for improving obesity status, which has both an antidepressant action and Z or stress reduction action, and is easy to prepare.
  • the invention of claim 1 is an obesity improving agent characterized by comprising a cypress essential oil.
  • the invention of claim 1 is also an obesity improving agent characterized in that it contains cypress essential oil.
  • the invention of claim 1 is an obesity improving agent characterized by containing cypress essential oil as an active ingredient.
  • the invention of claim 2 is an obesity-condition improving agent characterized by having a ⁇ 3 -force force.
  • the invention of claim 2 is also an obesity condition improving agent characterized by containing ⁇ 3 -strength.
  • the invention of claim 2 is an obesity condition improving agent characterized by containing ⁇ 3 -strength as an active ingredient.
  • the invention of claim 3 is characterized in that in the invention of claim 1 or 2, it further has an antidepressant action and a wrinkle or stress reducing action. That is, the obesity condition-improving agent is further characterized by having an antidepressant action, the obesity condition-improving agent is further having a stress-reducing action, and the obesity condition-improving agent is characterized by an antidepressant action and It further has a stress reducing effect.
  • the invention of claim 3 is also an invention characterized in that, in the invention of claim 1 or 2, the obesity state is improved by an antidepressant action and an epilepsy or stress reducing action.
  • the invention of claim 4 is an external preparation for skin containing the obesity condition-improving agent of any one of claims 1 to 3, and the invention of claim 5 is any of claims 1 to 3.
  • the A fragrance comprising an obesity-condition improving agent.
  • the invention of claim 6 is an invention of a method of using a fragrance containing cypress essential oil or ⁇ 3-strength for improving obesity.
  • the obesity condition-improving agent of the present invention As one of the functions of the obesity condition-improving agent of the present invention, the obesity condition disappears from the obesity condition, that is, the phenomenon is slimming. Therefore, the obesity condition-improving agent of the present invention is expressed as a slimming agent. You can also.
  • the cypress essential oil in the present invention is a known essential oil, and an Italian cypress essential oil is particularly preferable.
  • the Italian cypress essential oil can be prepared from a cypress plant of the genus Cypressaceae by a conventional method, but a commercially available product may be purchased.
  • the ⁇ 3-force len in the present invention is a known synthetic fragrance compound, and can be obtained by extraction from a natural product, or obtained by a biochemical synthesis method or a known chemical synthesis method. You can also purchase a commercial product.
  • a feature of the present invention is that the above-mentioned Cypress essential oil or ⁇ 3-strength is used as an obesity improving agent.
  • the improvement of obesity state here means reducing the degree of obesity, and also includes maintaining the degree of obesity. Therefore, the agent for improving obesity condition is an agent having the property 'function of reducing the degree of obesity and also includes an agent for maintaining the degree of obesity.
  • the obesity condition-improving agent of the present invention further has an antidepressant action and an epilepsy or stress-reducing action.
  • the antidepressant action is well known in the pre-application, and there are various causes and reasons for depression, and one person is able to change the condition as much as possible.
  • the stress reduction effect is also well known before the filing of this application. For example, it refers to the human power that has received stress due to the influence of the complex social environment in recent years.
  • the agent for improving obesity condition in the present invention may be added with other binders as long as the intended purpose can be achieved. These compounding agents will be described later.
  • the obesity condition-improving agent of the present invention may be contained in an external preparation for skin.
  • external preparations for skin include emulsions, creams, lotions, cosmetics, packs, facial cleansers, body soaps, makeup agents, bath preparations, fragrances, shampoos, hair treatments, hair styling agents, hair nourishing agents, hair restorers, etc. (Including medicated cosmetics), ointments, patches, patches Any of external medicines such as pills and liniments may be used.
  • the amount of the external preparation for skin to contain the agent for improving obesity condition of the present invention cannot be defined unconditionally because the optimal range differs depending on the external preparation for skin, but for example, 0.1% for external preparation for skin. It is preferable to contain ⁇ 20% by weight. 0.1 ⁇ : It is more preferred to contain L0% by weight.
  • the obesity condition-improving agent of the present invention can also be incorporated into oral care products such as toothpaste and mouthwash, foods and the like.
  • the compounding amount of the obesity condition improving agent is not particularly limited. For example, it is preferable to contain 0.1 to 20% by weight with respect to the product, food, etc. 0.1 to 10% by weight is more preferable. preferable.
  • the obesity condition-improving agent of the present invention can be contained in a fragrance such as a room fragrance, a car fragrance, an aroma candle, an aroma oil, etc. as it is or by mixing and mixing with other ingredients. .
  • the amount of the fragrance containing the agent for improving obesity condition of the present invention cannot be generally specified because the optimum range varies depending on the fragrance, but for example, 0.5 to: It is preferable to contain L00% by weight.
  • the present invention provides a composition for improving obesity which consists essentially of cypress essential oil and base power. Also provided is a composition for improving obesity which is essentially composed of ⁇ 3 -strength and a base.
  • the base means a substance that can carry Cypress essential oil or ⁇ 3 -strength, and any substance that can carry Cypress essential oil or ⁇ 3 -strength is used. Is possible. Representative examples include, but are not limited to, various solvents such as alcohols and various oils such as petrolatum.
  • the present invention also provides a method of using a fragrance containing cypress essential oil or ⁇ 3-strength to improve obesity.
  • a method of using a fragrance containing cypress essential oil or ⁇ 3-strength to improve obesity include a method of evaporating a fragrance containing cypress essential oil or ⁇ 3 -strength in a space where a person lives to improve obesity.
  • spaces in which people live include, but are not limited to, spaces in offices, health maintenance, and, in some cases, fitness spaces for beauty and living spaces such as in living rooms and bathrooms.
  • the method can also be said to be the use of cypress essential oils or fragrances containing ⁇ -3-carene as an environmental flared lance to improve obesity.
  • the method of volatilization is not particularly limited, and a fragrance containing Cypress essential oil or ⁇ 3-power lenght is volatilized at a predetermined site in the aeration apparatus. And a method of volatilizing in the space together with air, a method of arranging an arbitrary fragrance volatilization device in the space, and volatilizing perfume containing Cypress essential oil or ⁇ 3 -power len in the space, and the like.
  • peppermint essential oil also has an improvement in obesity status, although it is not as effective as an obesity improvement agent as Cypress essential oil or ⁇ 3 -strength.
  • a conventional compounding agent may be added to the external preparation for skin or fragrance according to the present invention.
  • These added ingredients include water (purified water, hot spring water, deep water, ion-exchanged water, etc.) and solvents (alcohols, polyhydric alcohols, etc.) that are commonly used in preparations for external preparations for skin and external medicine Etc.)
  • surfactant examples include polyoxyethylene glyceryl fatty acid esters such as polyoxyethylene monostearate glyceryl and polyoxyethylene monooleate glyceryl; monomyristate hexaglyceryl, monolaurate decaglyceryl, monostearate Polyglycerin fatty acid esters such as decaglyceryl acid; Polyoxyethylene monomyristate Polyoxyethylene sorbitan fatty acid esters such as sorbitan polyoxyethylene monostearate, sorbitan polyoxyethylene tristearate; Polyoxyethylene hydrogenated castor oil, polyoxyethylene Polyoxyethylene hardened castor oil such as hardened castor oil; polyoxyethylene cholesteryl ether, polyoxyethylene cholesteryl ether, etc.
  • polyoxyethylene glyceryl fatty acid esters such as polyoxyethylene monostearate glyceryl and polyoxyethylene monooleate glyceryl
  • Polyoxyethylene cholesteryl ethers polyoxyethylene phytosteryl ethers, polyoxyethylene phytosteryl ethers such as polyoxyethylene phytosteryl ethers; polyethylene glycol fatty acid esters such as polyoxyethylene glycol monolaurate and polyoxyethylene glycol monostearate; Polyoxyethylene alkyl ethers such as polyoxyethylene lauryl ether, polyoxyethylene benoyl ether, polyoxyethylene cetyl ether, polyoxyethylene stearyl ether; polyoxyethylene polyoxypropylene cetyl ether, polyethylene Examples include polyoxyethylene polyoxypropylene alkyl ethers such as reoxyethylene polyoxypropylene tetradecyl ether; polyoxyethylene alkyl ethers such as polyoxyethylene nonyl phenyl ether and polyoxyethylene octyl phenyl ether; .
  • fatty acid salts such as sodium laurate, sodium myristate, and sodium palmitate
  • polyoxyethylene such as sodium polyoxyethylene lauryl ether, sodium polyoxyethylene cetyl ether, sodium dipolyoxyethylene cetyl ether phosphate Ethyl alkyl ether phosphates
  • Acyl taurine salts such as sodium cocoyl methyl taurate and sodium stearoyl methyl taurate
  • Alkyl sulfates such as sodium lauryl sulfate and sodium cetyl sulfate
  • Sodium polyoxyethylene lauryl ether sulfate, Polyoxyethylene urea ether Examples thereof include polyoxyethylene alkyl ether sulfates such as sodium sulfate. You can use one or more of these!
  • a polyoxyethylene unit is about 3-60.
  • Examples of the high molecular weight compound include gum arabic, xanthan gum, tara gum, gati gum, carrageenan, cara gum, guar gum, tamarind seed gum, methyl cellulose, hydroxy methenoresenolellose, hydroxy ethyl cellulose, polyvinyl alcohol, hydroxy pour cellulose , Carboxymethyl cellulose, etc .; (meth) acrylic acid '(meth) acrylic acid alkyl copolymer, (meth) acrylic acid alkyl. Styrene copolymer, poly (acetate butyl), butylpyrrolidone.
  • Styrene copolymer acrylic-silicone copolymer Polymers of polymers, trimethylsiloxanes; curdlan, xanthan gum, dielan gum, hyaluronic acid, alkaline genus-producing polysaccharides such as polysaccharides, and one or more of these It is possible.
  • Oils include liquid paraffin, squalane, petrolatum, polyisobutylene, polybutene, Hydrocarbons such as paraffin wax, ceresin wax, microcrystalline wax, and Phytschatrops wax; fats and oils such as moscow, olive oil, castor oil, mink oil, and mash demian nut oil; montan wax, beeswax, carnau Waxes such as waxes, candelilla wax, gay wax; jojoba oil, cetyl isooctanoate, isopropyl myristate, isopropyl normitate, octyldodecyl myristate, glyceryl trioctanoate, diglyceryl disostearate, triisostearin Diglyceryl acid, glyceryl tribehenate, pentaerythritol ester of rosin acid, neopentyl glycol dioctanoate, cholesterol fatty acid
  • an agent for improving obesity is provided that is excellent in the effect of improving obesity.
  • This obesity-improving agent can be prepared by simple operations, and can be easily added to and blended with familiar products.
  • an extremely excellent effect is exhibited especially when blended with an external preparation for skin or a fragrance.
  • the present invention is extremely practical.
  • a body soap was prepared by the following preparation procedure.
  • Table 1 shows the body soap prescriptions.
  • ingredients 4 to 6 in Table 1 were uniformly mixed at 75 ° C. to obtain a mixture A.
  • components 7 to 9 are uniformly mixed and dissolved at 75 ° C., and added to and mixed with the mixture A to neutralize. After cooling the neutralized mixture, ingredients 1-3 and ingredients 10, 11 were collected to obtain a body soap.
  • Plant essential oil In the table, the plant essential oil is an Italian cypress essential oil. The essential oil was purchased from Bio prises (hereinafter the same).
  • a body soap was prepared by the following preparation procedure.
  • Table 2 shows the body soap prescriptions.
  • Palm oil fatty acid jetanolamide 3. 8
  • ⁇ -3-Carene was purchased from 11 (11 ⁇ 11 Chemical Company Inc. (hereinafter the same)
  • the plant essential oil is one of laurel essential oil, neroli essential oil, ginger essential oil, and coffee essential oil.
  • Laurel essential oil and neroli essential oil were purchased from Bio prises, Ginger essential oil was purchased from Ungerer, and coffee essential oil was purchased from Danisco (hereinafter the same).
  • Body jewel was prepared by the following procedure. Table 3 shows the prescriptions for Body Gier. (Body Jewel preparation procedure)
  • the plant essential oil is a cypress essential oil.
  • Body jewel was prepared by the following procedure. Table 4 shows the prescriptions for Body Gier. (Body Jewel preparation procedure)
  • ingredients 1 to 6 in Table 2 were uniformly mixed at 70 ° C. to obtain a mixture A. Thereafter, the same operation as in Example 3 was performed to obtain a body gel.
  • the plant essential oil is one of laurel essential oil, neroli essential oil, ginger essential oil, and coffee essential oil.
  • a bath essence was prepared by the following procedure. Table 5 shows the nose essence prescriptions.
  • the plant essential oil is a cypress essential oil.
  • Nose essence was prepared by the following procedure. Table 6 shows the prescriptions for luminescence. (Bath essence preparation procedure)
  • the plant essential oil is one of laurel essential oil, neroli essential oil, ginger essential oil, and coffee essential oil.
  • Index weight (kg) Z height 2 (m)) was conducted on obese students (20 students) who showed 25 or more .
  • the salivary cortisol reduction effect was explained to the subjects using the gamma-one-coated cortisol measurement kit by explaining the precautions (meal time, designated food and drink prohibited, saliva collection time, etc.) to each individual.
  • the saliva was collected. Put the absorbent cotton of the measurement kit in the mouth, and after 2-3 minutes (appropriately, the absorbent cotton is covered with saliva and lightly bites and oozes out).
  • the absorbent cotton is returned to the kit container, and after freezing, concentration analysis is performed.
  • the analysis method is the Radioimmune Assay (RIA), and the measuring instrument is the Autouel Gamma System AceuFLEX a 7010.
  • RIA Radioimmune Assay
  • the measuring instrument is the Autouel Gamma System AceuFLEX a 7010.
  • weight loss means both weight loss and body fat percentage reduction.
  • laurel essential oil did not show a significant weight loss effect, and neroli essential oil, ginger essential oil, and coffee essential oil tended to increase in both body weight and body fat percentage.
  • Cypress essential oil and ⁇ -3-carene also contributed to weight loss.
  • eau de toilette was prepared by a conventional method.
  • Example 9 Preparation of Body Lotion Containing Obesity Condition Improvement Agent Based on the following formulation examples, a body lotion was prepared by a conventional method.
  • Body milk was prepared by the following procedure. The formula for body milk is shown in Formulation Example 4.
  • an aroma oil was prepared by a conventional method.
  • room fredalance was prepared by a conventional method.
  • room fredalance was prepared by a conventional method.
  • the present invention also includes the invention described below.
  • Cypress essential oil and base power A composition essentially composed of a novel composition characterized by being able to improve obesity.
  • a novel composition characterized in that it is a composition essentially composed of ⁇ 3 -strength and a base and can improve obesity.
  • Cypress essential oil and base power It is a composition that is essentially composed, it can improve obesity, and the strength also has an antidepressant action and acupuncture or stress reduction action. New composition.
  • a composition consisting essentially of ⁇ 3 -strength and a base, which is capable of improving obesity and also has an antidepressant action and an acupuncture or stress reducing action.
  • New composition consisting essentially of ⁇ 3 -strength and a base, which is capable of improving obesity and also has an antidepressant action and an acupuncture or stress reducing action.
  • Cypress essential oil and base power A composition essentially composed of a novel composition characterized in that it can improve obesity and is useful as a skin external preparation or fragrance.
  • the new composition is stored so that it can freely come into contact with air, and through the air in the space where the new composition is stored, Cypress essential oil or ⁇ -3-calen from the new composition, Alternatively, a method for improving an obesity state, comprising incorporating a volatile component containing cypress essential oil or ⁇ 3 -strength into the body.

Abstract

Le problème à résoudre dans le cadre de la présente invention consiste à trouver un excellent agent destiné à atténuer les pathologies liées à l’obésité. La présente invention concerne un excellent agent destiné à atténuer les pathologies liées à l’obésité, qui possède en outre un effet antidépresseur et/un effet de réduction du stress. Cet agent peut être aisément préparé. La solution proposée est d’utiliser l’huile essentielle de cyprès ou le δ-3-carène en tant que principe actif en vue d’atténuer les pathologies liées à l’obésité. Il est avantageux d’utiliser l’agent d’atténuation des pathologies liées à l’obésité ainsi obtenu dans une préparation cutanée externe ou une fragrance. Il est également possible de volatiliser un parfum, qui contient de l’huile essentielle de cyprès ou du δ-3-carène, dans un espace où vivent des êtres humains.
PCT/JP2006/320476 2005-11-30 2006-10-13 Agent attenuant les pathologies liees a l’obesite WO2007063648A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2007547866A JP5814495B2 (ja) 2005-11-30 2006-10-13 肥満状態改善剤
TW095144356A TW200730185A (en) 2005-11-30 2006-11-30 Improving agent for obesity and usage thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005345543 2005-11-30
JP2005-345543 2005-11-30

Publications (1)

Publication Number Publication Date
WO2007063648A1 true WO2007063648A1 (fr) 2007-06-07

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PCT/JP2006/320476 WO2007063648A1 (fr) 2005-11-30 2006-10-13 Agent attenuant les pathologies liees a l’obesite

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Country Link
JP (1) JP5814495B2 (fr)
TW (1) TW200730185A (fr)
WO (1) WO2007063648A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011051970A (ja) * 2009-08-07 2011-03-17 Kose Corp 睡眠改善用香料組成物およびこれを含有する化粧料、並びに睡眠を改善する方法
JP2021031458A (ja) * 2019-08-27 2021-03-01 中野Ｂｃ株式会社 熱産生タンパク質発現促進剤

Citations (1)

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JP2003113392A (ja) * 2001-10-04 2003-04-18 Kiyomitsu Kawasaki 芳香・消臭組成物および該芳香・消臭組成物を含有する人体用芳香・消臭剤

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011051970A (ja) * 2009-08-07 2011-03-17 Kose Corp 睡眠改善用香料組成物およびこれを含有する化粧料、並びに睡眠を改善する方法
JP2021031458A (ja) * 2019-08-27 2021-03-01 中野Ｂｃ株式会社 熱産生タンパク質発現促進剤
JP7298841B2 (ja) 2019-08-27 2023-06-27 中野Ｂｃ株式会社 熱産生タンパク質発現促進剤

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JPWO2007063648A1 (ja) 2009-05-07
JP5814495B2 (ja) 2015-11-17

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