WO2007052730A1 - Fixation pour une injection intravitreenne - Google Patents

Fixation pour une injection intravitreenne Download PDF

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Publication number
WO2007052730A1
WO2007052730A1 PCT/JP2006/321919 JP2006321919W WO2007052730A1 WO 2007052730 A1 WO2007052730 A1 WO 2007052730A1 JP 2006321919 W JP2006321919 W JP 2006321919W WO 2007052730 A1 WO2007052730 A1 WO 2007052730A1
Authority
WO
WIPO (PCT)
Prior art keywords
injection
eyeball
fixture
ring
intravitreal
Prior art date
Application number
PCT/JP2006/321919
Other languages
English (en)
Japanese (ja)
Inventor
Masafumi Uematsu
Michiko Koga
Takashi Kitaoka
Original Assignee
Nagasaki University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagasaki University filed Critical Nagasaki University
Priority to JP2007542796A priority Critical patent/JP5011542B2/ja
Publication of WO2007052730A1 publication Critical patent/WO2007052730A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/427—Locating point where body is to be pierced, e.g. vein location means using ultrasonic waves, injection site templates

Definitions

  • the present invention relates to an intravitreal fixing device comprising an eyeball fixing device and an injection needle fixing plate.
  • Intravitreal injection This is an indispensable therapeutic technique for ophthalmic treatment. This technique is
  • the insertion site it is necessary to measure the 3.5 mm area from the corneal end, which is the injection needle insertion site, but if the position is shifted, the retina, lens or ciliary body may be damaged. There is sex.
  • the insertion angle it is necessary to keep the insertion angle of the injection needle at an angle that does not touch the lens and the retina.
  • the penetration depth it is necessary not to make the penetration depth of the retinal injury injection needle too deep. Depending on the angle, there is a risk of damaging the retina if it is too deep.
  • the present inventors have developed an intravitreal injection fixture characterized by including an injection needle fixing plate in addition to the conventional eyeball fixator.
  • the present invention comprises an injection needle fixing plate having an injection needle insertion hole, and an eyeball fixing device having a non-smooth eyeball contact surface and a ring for fixing the position of the injection needle insertion hole on the eyeball.
  • An intravitreal injection fixture is provided.
  • the present invention provides a novel intravitreal injection fixture.
  • a glass of the present invention comprising: an injection needle fixing plate having an injection needle insertion hole; and an eyeball fixing device for fixing the position of the injection needle insertion hole on the eyeball, comprising a ring having a non-smooth eyeball contact surface
  • FIG. 1 is a side view of the fixing device for intravitreal injection according to the present invention.
  • FIG. 2 is a top view of the intravitreal injection fixture of the present invention.
  • Fig. 3 is an enlarged side view of the ring and the needle needle plate
  • FIG. 4 is an enlarged side view with the injection needle inserted.
  • FIG. 5 is a schematic view of the state where the intravitreal injection fixture of the present invention is applied to the eyeball as seen from above.
  • FIG. 6 is a schematic view of a state in which the injection needle is inserted by applying the intravitreal injection fixture of the present invention to a ball.
  • Fig. 7 is a photograph showing the fixation of the eyeball for intravitreal injection.
  • Fig. 8 is a photograph showing how the insertion part is measured.
  • Fig. 9 is a photograph showing a state where the injection needle is inserted.
  • FIG. 10 is a photograph showing how the aqueous humor is removed.
  • Figure 11 is a photograph showing the injection into the vitreous.
  • Figure 12 is a photograph showing how the aqueous humor is removed.
  • a novel intravitreal injection fixture of the present invention includes an injection needle fixing plate having an injection needle insertion hole, and a ring having a non-smooth eyeball contact surface, and fixes the position of the injection needle insertion hole on the eyeball. It is composed of an intravitreal injection fixture consisting of:
  • the intravitreal injection fixture of the present invention is obtained by integrally forming an injection needle fixing plate on a conventional eyeball fixator and can easily and accurately perform intravitreal injection. Therefore, by using the intravitreal injection fixture of the present invention, the risk of medical errors associated with intravitreal injection can be greatly reduced.
  • FIG. 2 shows a top view of the intravitreal injection fixture of the present invention.
  • the ring 3 has an opening 5
  • further injectable fixing plate 4 Note Ihari insertion hole 6
  • FIG. -'''Fig. 3 is an enlarged side view of the ring and needle fixing plate.
  • the injection fixing plate 4 has a needle insertion hole 6, and the ring 3 has a spike-like projection 7 ′ that is not smooth.
  • Fig. 4 is an enlarged side view with the injection needle inserted.
  • the injection needle 8 is inserted into the injection needle insertion hole 6.
  • FIG. 5 shows a schematic view of the state in which the intravitreal injection fixture of the present invention is applied to the eyeball as seen from above.
  • the ring 3 of the intravitreal injection fixture 1 is placed on the cornea 10 of the eyeball 9, and the injection fixing plate 4 attached to the ring 3 has a needle insertion hole 6.
  • Fig. 6 shows a schematic view of the state in which the injection needle is inserted by applying the intravitreal injection fixture of the present invention to the eyeball.
  • the injection needle 8 is inserted into the vitreous body 11 of the eyeball 9 through the injection needle insertion hole 6. Since the position and angle of the injection needle insertion hole 6 are appropriate, the injection needle 8 does not damage the lens 12 or the like.
  • the eyeball fixing device 2 and the injection needle fixing plate 4 are not necessarily formed integrally, and it is also preferable in the present invention that the eyeball fixing device 2 is connected to the injection needle fixing plate 4 via an adapter ”.
  • the intravitreal fluid can be extracted by inserting the injection needle into the vitreous and then performing an anterior chamber puncture. Since the intraocular pressure is not increased since the intraocular pressure is not extracted, the ocular fixation ring of the present invention has an opening for anterior chamber puncture. Having 5 is a preferred embodiment.
  • the diameter of the ring 3 of the eyeball fixator 2 is preferably 10 mm or more and 16 mm or less, and more preferably 13 mm.
  • the diameter of the ring 3 is not particularly limited, but can be adjusted as appropriate according to the size of the cornea of the specimen undergoing the intravitreal injection procedure.
  • Eye fixing device If the contact surface of the ring 3 of the ring 3 is a flat ellipse, it will be inconvenient because it will slip even if it tries to fix the ring to the eyeball.
  • the shape of the eyeball contact surface of the ring of the eyeball fixator is not particularly limited as long as it is not smooth. In the present invention, it is a preferred aspect that the eyeball contact surface of the ring of the eyeball fixture has spike-like protrusions or unevenness of a snow tire pad.
  • the optimal injection site is generally 3.5 mm from the edge of the cornea. If this position is shifted, the retina, lens or ciliary body may be damaged, so the injection site must be set accurately. Since the ring 3 of the eyeball fixation device 2 is sized so as to almost cover the cornea, by installing the needle insertion hole 6 so that the injection needle can be inserted at a position about 3.5 mra from the ring 3 It is not necessary to measure at the time of insertion of the injection needle, and intravitreal injection can be performed safely.
  • the distance between the injection needle insertion hole 6 and the ring 3 is a force of 3.0 thigh or more and 5.0 mm or less.
  • the present invention is not limited to this.
  • the distance 13 between the insertion hole and the ring means the distance between the center portion of the injection needle insertion hole 6 and the end on the side where the ring 3 is connected to the injection needle fixing plate 4. To do.
  • the distance 13 between the insertion hole and the ring is 3.5 mm, which is the most preferable aspect in the present invention.
  • the insertion angle of the injection needle is necessary to keep the insertion angle of the injection needle at an angle that does not touch the crystalline lens and the retina.
  • the angle between the plane (ring plane 14) and the needle insertion hole 6 (ring angle 15 between the plane and the injection needle) formed by the ring 3 of the eyeball fixator 2 that fixes the eyeball is 50 degrees.
  • the above 70 degrees or less is a preferred embodiment in the present invention, but is not limited thereto.
  • the angle between the plane (ring plane 14) formed by the ring of the eyeball fixator and the injection needle insertion hole is 60 degrees. It is.
  • the insertion depth of the injection needle is also important. It is necessary not to squeeze the needle into the needle too deeply, and depending on the piercing angle, it will damage the mesh. If the length of the needle insertion hole is 3, a 27-gauge needle with a length of 19 mra will be about 15 mm to enter the vitreous, and will not be deep enough to penetrate the retina. Considering this, the length 16 of the injection needle insertion hole in the eyeball fixing device is l. Omra or more and 6. Omm or less, which is a preferred embodiment in the present invention, but is not limited thereto. is not. The length 16 of the needle insertion hole in the eyeball fixing device is 5.0, which is the most preferable aspect in the present invention.
  • the first advantage of the intravitreal injection rod fixing device is that the risk of conventional intravitreal injection can be avoided.
  • the second advantage is that the stability of eyeball fixation at the time of injection is good. Therefore, once the needle is inserted, the needle is fixed in the optimal position even if you take your hand off. In addition, the syringe can be moved and injected easily with one hand.
  • a third advantage is that the anterior aqueous humor can be removed while the injection needle is fixed. After inserting the injection needle, the anterior aqueous humor can be removed by releasing the hand once. As a result, high intraocular pressure after intravitreal injection can be prevented. In addition, it is possible to remove the anterior aqueous humor from the intravitreal injection fistula in advance using conventional techniques.
  • a fourth advantage is that intravitreal injection using the device of the present invention is a very simple procedure. Because there are fewer procedures and higher safety compared to conventional methods, intravitreal injection can be performed more easily than in the past.
  • FIG. 7 shows the insulator.
  • FIG. 7A shows a state in which the eyeball is fixed by a conventional procedure
  • FIG. 7B shows a state in which the eyeball is fixed by a procedure using the vitreous injection fixing tool of the present invention.
  • the fixture is more stable because it can fix more than 3/4 around the cornea.
  • the left and right injection needles of the eyeball are for fixing the eyeball and are not related to the procedure.
  • the fixation ring is on the cornea.
  • Fig. 8 shows the state of measuring the measurement insertion part located 3.5 mm from the end of the cornea using a conventional procedure.
  • the injection needle fixing plate has the injection needle insertion hole, so there is no need to measure the insertion portion.
  • FIG. 9A shows a state where the needle is inserted by a conventional technique
  • FIG. 9B shows a state where the needle is inserted by a technique using the vitreous injection fixture of the present invention.
  • the optimal insertion site, insertion angle, and insertion are performed by inserting the injection needle into the injection needle insertion hole of the injection fixing plate. Depth of penetration can be obtained.
  • the syringe is fixed, there is an advantage that there is no problem even if the hand is released after insertion.
  • the vitreous injection fixture of the present invention when used, it is injected at this stage, that is, after the injection needle is inserted, into the vitreous body.
  • the anterior aqueous humor can be removed before As a result, temporary high intraocular pressure associated with intravitreal injection can be avoided.
  • the anterior aqueous humor is removed using the vitreous injection fixture of the present invention. It is possible to remove the aqueous humor from the opening of the ring of the fixation plate for injection, and the syringe is fixed even if the hand is released.
  • FIG. 11A shows the injection into the vitreous using a conventional procedure
  • Fig. 11B shows the injection into the vitreous using a procedure using the vitreous injection fixture of the present invention.
  • conventional technology careful attention must be paid to the insertion angle and depth.
  • holding the syringe with one hand and fixing the eyeball with only one point of insertion to push down the syringe with the other hand is very unstable.
  • the fixation is very good, and the injection is completed only by depressing the syringe.
  • Figure 12 shows how the aqueous humor is removed using conventional technology.
  • the conventional technique it is necessary to remove the anterior aqueous humor after the injection into the vitreous, so that the intraocular pressure continues until the anterior aqueous humor is removed. If the anterior aqueous humor is removed prior to the injection of vitreous fistula in the prior art, there is a problem that the eyeball is not stretched and the eyeball is distorted during intravitreal injection, which makes it difficult to insert. .
  • a novel intravitreal injection fixture is provided.
  • the intravitreal injection fixture of the present invention By using the intravitreal injection fixture of the present invention, the risk of conventional intravitreal injection can be avoided and the procedure is very simple. Therefore, the intravitreal injection fixture of the present invention is very useful as a medical instrument in the ophthalmic field.

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne une nouvelle fixation pour une injection intravitréenne. C'est-à-dire qu’elle concerne une fixation pour une injection intravitréenne comprenant : une plaque de fixation d’aiguille à injection (4) qui comporte un trou d’insertion d’aiguille à injection (6); et une fixation du globe oculaire destinée à fixer la position dudit trou (6) sur le globe oculaire qui comporte un anneau (3) ayant une face non lisse devant être en contact avec le globe oculaire. L’utilisation de la présente fixation pour une injection intravitréenne rend possible d’éviter le risque accompagnant l’injection intravitréenne existante et la technique pour cela est très simple. C'est-à-dire que la fixation décrite ci-dessus pour une injection intravitréenne permet une injection intravitréenne extrêmement sûre et aisée.
PCT/JP2006/321919 2005-10-31 2006-10-26 Fixation pour une injection intravitreenne WO2007052730A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2007542796A JP5011542B2 (ja) 2005-10-31 2006-10-26 硝子体内注射用固定具

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005-316218 2005-10-31
JP2005316218 2005-10-31

Publications (1)

Publication Number Publication Date
WO2007052730A1 true WO2007052730A1 (fr) 2007-05-10

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PCT/JP2006/321919 WO2007052730A1 (fr) 2005-10-31 2006-10-26 Fixation pour une injection intravitreenne

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JP (1) JP5011542B2 (fr)
WO (1) WO2007052730A1 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1033357C2 (nl) * 2007-02-08 2008-08-11 Arnaldo Goncalves Inrichting voor het met behulp van een injectie-naald intraoculair toedienen van een substantie, bijvoorbeeld een medicament, in een menselijk of dierlijk oog.
FR2928536A1 (fr) * 2008-03-14 2009-09-18 Inst Nat Sante Rech Med Dispositif d'injection dans l'oeil
JP2010515505A (ja) * 2007-01-09 2010-05-13 フォヴェア ファルマシューティカル 眼内注射装置
JP2013501579A (ja) * 2009-08-10 2013-01-17 サーモディクス，インコーポレイテッド 硝子体内に注射するための方法、装置、及び組成物
WO2014125463A1 (fr) 2013-02-18 2014-08-21 Eyevensys Dispositif pour le traitement d'une maladie oculaire
US9144516B2 (en) 2007-02-08 2015-09-29 Sharpsight B.V. Device for intraocular administration of a substance, for example a medication, into a human or animal eye by means of a hypodermic needle
WO2016083669A1 (fr) 2014-11-28 2016-06-02 Visionisti Oy Outil thérapeutique oculaire
EP3081198A1 (fr) 2015-04-14 2016-10-19 Eyevensys Dispositif d'électroporation pour l'oeil avec un support et avec une électrode aiguille
EP3785684A1 (fr) 2019-09-02 2021-03-03 Medical Workshop B.V. Dispositif d'assistance d'injection oculaire

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5645794B2 (ja) * 2011-10-31 2014-12-24 伸吉 戸塚 ゲージ付き角膜保護キャップ

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JP2003518987A (ja) * 2000-01-06 2003-06-17 ザ・ユニバーシティ・オブ・シドニー 眼内注入のためのガイド手段
JP2005501602A (ja) * 2001-08-29 2005-01-20 カルバーリョ、リカルド エイ．ピー． デ 治療薬を組織に一方向送達するための封鎖可能な移殖型装置
JP2005504565A (ja) * 2001-06-28 2005-02-17 レオン・シー・ラハイ 眼科レーザ手術を支援するための多機能手術用器具

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Publication number Priority date Publication date Assignee Title
JP2003518987A (ja) * 2000-01-06 2003-06-17 ザ・ユニバーシティ・オブ・シドニー 眼内注入のためのガイド手段
JP2005504565A (ja) * 2001-06-28 2005-02-17 レオン・シー・ラハイ 眼科レーザ手術を支援するための多機能手術用器具
JP2005501602A (ja) * 2001-08-29 2005-01-20 カルバーリョ、リカルド エイ．ピー． デ 治療薬を組織に一方向送達するための封鎖可能な移殖型装置

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010515504A (ja) * 2007-01-09 2010-05-13 フォヴェア ファルマシューティカル 眼内注射装置
JP2010515505A (ja) * 2007-01-09 2010-05-13 フォヴェア ファルマシューティカル 眼内注射装置
WO2008097072A1 (fr) * 2007-02-08 2008-08-14 Arnaldo Goncalves Dispositif pour l'administration intraoculaire d'une substance, par exemple d'un médicament, dans un œil humain ou animal au moyen d'une aiguille hypodermique
NL1033357C2 (nl) * 2007-02-08 2008-08-11 Arnaldo Goncalves Inrichting voor het met behulp van een injectie-naald intraoculair toedienen van een substantie, bijvoorbeeld een medicament, in een menselijk of dierlijk oog.
US9144516B2 (en) 2007-02-08 2015-09-29 Sharpsight B.V. Device for intraocular administration of a substance, for example a medication, into a human or animal eye by means of a hypodermic needle
US9180044B2 (en) 2008-03-14 2015-11-10 Institute National De La Sante Et De La Recherche Medicale Eye injection device
JP2014100576A (ja) * 2008-03-14 2014-06-05 Inst National De La Sante & De La Recherche Medicale 眼内注射装置
AU2009232117B2 (en) * 2008-03-14 2014-12-11 Institut National De La Sante Et De La Recherche Medicale Eye injection device and method
WO2009122030A1 (fr) * 2008-03-14 2009-10-08 Institut National De La Sante Et De La Recherche Medicale Dispositif d'iniection dans l'oeil
FR2928536A1 (fr) * 2008-03-14 2009-09-18 Inst Nat Sante Rech Med Dispositif d'injection dans l'oeil
JP2011513016A (ja) * 2008-03-14 2011-04-28 アンスティテュ ナスィヨナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 眼内注射装置
US9750635B2 (en) 2008-03-14 2017-09-05 Institut National De La Sante Et De La Recherche Medicale Eye injection device
JP2013501579A (ja) * 2009-08-10 2013-01-17 サーモディクス，インコーポレイテッド 硝子体内に注射するための方法、装置、及び組成物
WO2014125463A1 (fr) 2013-02-18 2014-08-21 Eyevensys Dispositif pour le traitement d'une maladie oculaire
EP3223760A4 (fr) * 2014-11-28 2018-12-12 Visionisti OY Outil thérapeutique oculaire
WO2016083669A1 (fr) 2014-11-28 2016-06-02 Visionisti Oy Outil thérapeutique oculaire
US11071643B2 (en) 2014-11-28 2021-07-27 Visionisti Oy Ocular therapeutics tool
JP2017536221A (ja) * 2014-11-28 2017-12-07 ヴィジョニスティ オイ 眼科治療用器具
EP3081198A1 (fr) 2015-04-14 2016-10-19 Eyevensys Dispositif d'électroporation pour l'oeil avec un support et avec une électrode aiguille
CN107708623A (zh) * 2015-04-14 2018-02-16 艾湾色斯公司 电穿孔装置
US10912939B2 (en) 2015-04-14 2021-02-09 Eyevensys Electroporation device
WO2016166172A2 (fr) 2015-04-14 2016-10-20 Eyevensys Dispositif d'électroporation
EP3785684A1 (fr) 2019-09-02 2021-03-03 Medical Workshop B.V. Dispositif d'assistance d'injection oculaire
NL2023743B1 (en) 2019-09-02 2021-05-12 Medical Workshop B V Ocular injection assist device

Also Published As

Publication number Publication date
JPWO2007052730A1 (ja) 2009-04-30
JP5011542B2 (ja) 2012-08-29

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