WO2007032343A1 - Dispositif d'injection de liquide medicamenteux - Google Patents

Dispositif d'injection de liquide medicamenteux Download PDF

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Publication number
WO2007032343A1
WO2007032343A1 PCT/JP2006/318060 JP2006318060W WO2007032343A1 WO 2007032343 A1 WO2007032343 A1 WO 2007032343A1 JP 2006318060 W JP2006318060 W JP 2006318060W WO 2007032343 A1 WO2007032343 A1 WO 2007032343A1
Authority
WO
WIPO (PCT)
Prior art keywords
tubular member
needle
inner needle
cover member
cover
Prior art date
Application number
PCT/JP2006/318060
Other languages
English (en)
Japanese (ja)
Inventor
Shigeru Nemoto
Isao Kimura
Original Assignee
Nemoto Kyorindo Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nemoto Kyorindo Co., Ltd. filed Critical Nemoto Kyorindo Co., Ltd.
Priority to JP2007535480A priority Critical patent/JP5053093B2/ja
Publication of WO2007032343A1 publication Critical patent/WO2007032343A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/06—Body-piercing guide needles or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/06—Body-piercing guide needles or the like
    • A61M25/0606—"Over-the-needle" catheter assemblies, e.g. I.V. catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel

Definitions

  • the present invention relates to a drug solution injection tool used for injecting a drug solution into a blood vessel, and particularly to a drug solution injection tool in which a flexible outer needle is placed in a blood vessel.
  • an injection needle When injecting a drug solution into a blood vessel of a subject, an injection needle may be directly attached to a drug solution container that is slidably inserted into a piston member of a cylinder member, and the injection needle may be directly punctured into a blood vessel.
  • a drug solution container that is slidably inserted into a piston member of a cylinder member
  • the injection needle may be directly punctured into a blood vessel.
  • the drug solution container and the injection needle are connected via a flexible extension tube, and the injection needle attached to the distal end portion of the extension tube is fixed to the subject.
  • the needle when the subject is a long-term hospitalized patient, the needle may be punctured many times. In such cases, an indwelling needle is used that places little burden on the subject even if it is placed in a blood vessel.
  • a fluoroscopic imaging device such as a CT (Computed Tomography) scanner or an MRI (Magnetic Resonance Imaging) device
  • CT Computer Tomography
  • MRI Magnetic Resonance Imaging
  • an indwelling needle may be used to inject a contrast medium in such a case.
  • an indwelling needle 10 exemplified as a chemical solution injection tool has an outer needle 11, an inner needle 12, and a tubular member 13.
  • the outer needle 11 is formed in a tubular shape with a flexible member, for example, silicone resin.
  • the inner needle 12 is formed of a hard member, for example, a stainless alloy in a sharp needle shape, and the inner needle 12 is inserted into the outer needle 11.
  • the tubular member 13 is formed in a tubular shape having a front end and a rear end opened with a hard and transparent resin or the like.
  • the rear end of the outer needle 11 is integrally connected to the opening at the front end of the tubular member 13.
  • an opening 14 at the rear end of the tubular member 13 is attached with a packing 14 that is an elastic member.
  • the inner needle 12 passes through the packing 14.
  • the packing 14 seals the opening at the rear end of the tubular member 13, and a knob-like portion 16 is formed in the body at the rear of the inner needle 12 from which the knocking force 14 protrudes.
  • the tubular member 13 has a tubular portion whose side force extends integrally and has an open end.
  • the front end of a separate flexible extension tube 17 is detachably attached to the tubular portion by a joint 18.
  • a chemical solution container such as a chemical solution syringe or a chemical solution bottle is detachably attached to the rear end of the extension tube 17.
  • the extension tube 17 is equipped with an exhaust valve (not shown) that is a means for removing bubbles, and this exhaust valve excludes bubbles from the liquid inside the extension tube 17.
  • the inner needle 12 is disposed inside the outer needle 11 and protrudes from the outer needle 11. 11 and the inner needle 12 are punctured into the blood vessel of the subject (not shown).
  • the knob-shaped portion 16 is pulled out, and the inner needle 12 is pulled out from the outer needle 11 and the tubular member 13 as shown in FIG. 121B. Then, the inside of the outer needle 11 and the tubular member 13 is filled with the blood of the subject flowing in. When the inner needle 12 is pulled out in this way, the hole formed in the packing 14 by the inner needle 12 is closed by the elasticity of the knocking 14 itself.
  • a chemical liquid container is connected to the rear end and the front end of the extension tube 17 filled with the chemical liquid is connected to the tubular member 13. Further, when the extension tube 17 is connected, bubbles are excluded from the liquid inside the tubular member 13 and the extension tube 17 by the exhaust valve provided in the extension tube 17.
  • the chemical solution can also be injected into the blood vessel of the subject via the extension tube 17 and the indwelling needle 10. Since the outer needle 11 pierced into the blood vessel is flexible, the physical burden on the subject while injecting the drug solution is reduced. The outer needle 11 is a flexible force. When the blood vessel is punctured, the inner side is held by the hard inner needle 12, so that the outer needle 11 can be easily punctured into the blood vessel.
  • Patent Document 1 Japanese Patent Application Laid-Open No. 07-328116
  • Patent Document 2 Japanese Patent Laid-Open No. 09-000629
  • Patent Document 3 Japanese Patent Laid-Open No. 10-015074
  • Patent Document 4 JP-A-10-028739
  • an indwelling needle in which a sheath-like cover member that expands and contracts in two stages is attached to the rear end opening of the tubular member, and the rear end of the inner needle is fixed to the inner rear end of the cover member in a contracted state.
  • the indwelling needle when the subject is punctured with the outer needle together with the outer needle and then the cover member is extended and separated from the tubular member, the extracted inner needle is positioned inside the extended cover member.
  • the present invention has been made in view of the above-described problems, and an object of the present invention is to provide a drug solution injector that can reliably cover the inner needle pulled out from the outer needle with a simple structure.
  • the drug solution injection tool of the present invention includes an outer needle, an inner needle, a tubular member, and a cover member, and is used for injecting a drug solution into a blood vessel.
  • the outer needle is flexible and at least the front part is placed in the blood vessel.
  • the inner needle is hard at least at the front part, and the front part is placed in the outer needle and punctured into the blood vessel.
  • the rear end portion of the outer needle is integrally connected to the front end opening, and the rear end opening force projects from the rear portion of the inner needle.
  • the cover member has a bellows structure that can be expanded and contracted so that the entire length of the inner needle can be accommodated in the extended state.
  • the rear end portion of the inner needle is fixed, and the front end portion is detachably attached to the rear end opening of the tubular member.
  • the cover member is separated from the tubular member by pulling the rear end of the cover member while the outer needle is punctured into the blood vessel of the subject together with the inner needle. Then, the inner needle is withdrawn from the outer needle and the tubular member, and is accommodated in the cover member.
  • the inner needle can be automatically accommodated in the cover member with a simple configuration that does not require an operation only for accommodating the inner needle in the cover member.
  • each component referred to in the present invention does not have to be a force or an independent entity.
  • a plurality of components may be formed as a single member, a certain component may be a part of another component, or a part of one component and another component. Some of the elements may overlap.
  • the front-rear direction is defined, but this is defined for the sake of convenience in explaining the relative relationship of each component. It does not limit the direction during use.
  • the front part in the present invention means a part from the front end to any position directed toward the rear end, and the rear part refers to a part from the rear end to any position directed toward the front end. I mean.
  • FIG. 1A is a longitudinal side view of an indwelling needle that is one embodiment of a drug solution injection device of the present invention, showing a state before puncturing by a subject.
  • FIG. 1B is a longitudinal side view of an indwelling needle that is an embodiment of the drug solution injector of the present invention, showing a state in which the inner needle has been pulled out.
  • FIG. 2 is an exploded perspective view showing a connection relationship between an indwelling needle, a chemical solution syringe that is a chemical solution container, and an injection head of the chemical injection device.
  • FIG. 3 is a perspective view showing the appearance of the chemical liquid injector.
  • FIG. 4 is a perspective view showing an appearance of a chemical liquid injection system.
  • FIG. 5A is a longitudinal side view of a first modified example of the indwelling needle shown in FIG. 1A, showing a state before puncturing by a subject.
  • FIG. 5B is a vertical side view of the first modified example of the indwelling needle shown in FIG. 1A, in which the inner needle is pulled out. Indicates the state.
  • ⁇ 6A A longitudinal side view of the second modified example of the indwelling needle shown in FIG. 1A, showing a state before puncturing by a subject.
  • FIG. 6B A longitudinal side view of the second modified example of the indwelling needle shown in FIG. 1A, showing a state in which the inner needle is pulled out.
  • FIG. 7A is a longitudinal side view of the third modified example of the indwelling needle shown in FIG. 1A, showing a state before being punctured by a subject.
  • FIG. 7B is a longitudinal side view of the third modified example of the indwelling needle shown in FIG. 1A, showing a state in which the inner needle is pulled out.
  • FIG. 8A is a longitudinal side view of the fourth modified example of the indwelling needle shown in FIG. 1A, showing a state before being punctured by a subject.
  • FIG. 1A A longitudinal side view of the fourth modified example of the indwelling needle shown in FIG. 1A, showing a state in which the inner needle has been pulled out.
  • FIG. 9A is a longitudinal side view of the fifth modified example of the indwelling needle shown in FIG. 1A, showing a state before puncturing by the subject.
  • FIG. 1A A vertical side view of the fifth modified example of the indwelling needle shown in FIG. 1A, showing a state in which the inner needle is pulled out.
  • FIG. 10A is a longitudinal side view of the sixth modified example of the indwelling needle shown in FIG. 1A, showing a state before being punctured by a subject.
  • FIG. 10B is a longitudinal side view of the sixth modified example of the indwelling needle shown in FIG. 1A, showing a state in which the inner needle is pulled out.
  • FIG. 11A is a longitudinal side view of a seventh modified example of the indwelling needle shown in FIG. 1A, showing a state before being punctured by a subject.
  • FIG. 1A A vertical side view of the seventh modified example of the indwelling needle shown in FIG. 1A, showing a state in which the inner needle has been pulled out.
  • [12A] A vertical side view of a conventional indwelling needle, showing the condition prior to puncture by the subject.
  • FIG. 12B A longitudinal side view of an indwelling needle of a conventional example, showing a state in which the inner needle is pulled out.
  • FIG. 12C A longitudinal side view of an indwelling needle of a conventional example, showing a state in which a chemical container is connected
  • This type of chemical injection system 1000 includes a chemical injection device 100, chemical syringes 200C and 200P that are chemical solutions containers (hereinafter simply referred to as 200 if they are not distinguished), and an indwelling needle 300 that is a chemical injection tool.
  • an MRI apparatus 400 that is a fluoroscopic imaging apparatus.
  • the MRI apparatus 400 includes a fluoroscopic imaging unit 401 and an imaging control unit 402 that are imaging execution mechanisms.
  • the fluoroscopic imaging unit 401 captures a fluoroscopic image of a subject (not shown), and the imaging control unit 402 controls the operation of the fluoroscopic imaging unit 401.
  • the chemical liquid syringe 200 includes a cylinder member 210 and a piston member 220 that is slidably inserted into the cylinder member 210.
  • the cylinder member 210 has a cylindrical hollow main body portion 211, and a conduit portion is formed at the closed front end of the main body portion 211. 212 is formed.
  • the rear end of the main body 211 of the cylinder member 210 is opened, and the piston member 220 is inserted into the opening force main body 211.
  • a cylinder flange 213 is formed on the outer periphery of the rear end of the cylinder member 210.
  • a piston flange 221 is formed on the outer periphery of the rear end of the piston member 220.
  • the drug solution syringe 200 includes a contrast syringe 200C filled with a contrast agent as a drug solution and a saline syringe 200P filled with a saline solution as a drug solution.
  • the chemical injection device 100 can be equipped with one contrast syringe 200C and one saline syringe 200P at a time.
  • the chemical liquid injector 100 includes an injection control unit 101 and an injection head 110 that are configured separately from each other. Injection control unit 101 and injection head 110 are connected to each other by communication cable 102.
  • the injection head 110 operates the chemical solution syringe 200 to be attached to inject the chemical solution into the subject.
  • the injection control unit 101 controls the operation of the injection head 110.
  • the injection head 110 is attached to the upper end of the caster stand 111 via the movable arm 112.
  • the injection head 110 has a head main body 113, and two semi-cylindrical concave portions 114 to which the chemical syringe 200 is detachably attached are formed on the upper surface of the head main body 113.
  • Each recess 114 is formed with a groove-like cylinder holding mechanism 116 that detachably holds the cylinder flange 211 of the chemical syringe 200.
  • a chemical injection mechanism 117 that holds and slides the piston flange 221 is disposed behind each recess 114.
  • Each chemical solution injection mechanism 117 has an ultrasonic motor (not shown) that does not generate a magnetic field even during operation as a drive source, and slides the piston member 220 by a screw mechanism (not shown) or the like.
  • contrast syringe 200C and the physiological saline syringe 2 OOP are individually attached to each recess 114 of the injection head 110, the subject is contrasted by the two recesses 114 and the two drug solution injection mechanisms 117.
  • a contrast injection mechanism 117C for injecting the agent and a saline injection mechanism 117P for injecting physiological saline are configured.
  • each part of the injection head 110 is made of a non-magnetic material.
  • a portion that is formed and cannot be formed of a non-magnetic material is shielded.
  • ultrasonic motors are made of non-magnetic metal such as phosphor bronze alloy (Cu + Sn + P), titanium alloy ( ⁇ -6 ⁇ ⁇ 4V), magnesium alloy (Mg + Al + Zn).
  • the head main body 113 and the like are made of nonmagnetic grease.
  • Injection control unit 101 has a main body housing 106, and operation panel 103, touch panel 104, speaker unit 105, and the like are arranged on the front surface thereof. Also, a separate controller unit 107 is wired to the injection control unit 101 via a connection connector 108.
  • the operation of the injection head 110 is basically controlled by a manual input operation to the injection control unit 101, but an operation panel 118 that accepts a simple manual input operation is an upper surface of the injection head 110. It is also formed at the rear.
  • the indwelling needle 300 of the present embodiment has an outer needle 310, an inner needle 320, a tubular member 330, a cover member 340, and an extension tube 350 as main components.
  • the outer needle 310 is formed into a thin tubular shape that can be easily bent but is difficult to expand and contract by, for example, a flexible silicone resin.
  • the inner needle 320 has a needle body 321 and a guide wire 322.
  • the needle body 321 is formed in a sharp shape, for example, with a hard stainless alloy.
  • the guide wire 322 is formed of, for example, a metal wire that is flexible but difficult to expand and contract.
  • the front end of the guide wire 322 is integrally connected to the rear end of the needle body 321.
  • the needle body 321 is formed in a hollow tubular shape in which the flow path 323 communicates with both the front end force and the rear end.
  • a guide wire 322 is inserted into the opening at the rear end of the needle body 321 and fixed by caulking or bonding.
  • the rear end of the flow path 323 of the needle body 321 is closed by fixing the guide wire 322.
  • An opening 324 communicating with the flow path 323 is formed on the rear side surface of the needle body 321.
  • the tubular member 330 has an outer needle support pipe 331 and a branch pipe 332 formed in a hollow structure in which the front end and the rear end are opened.
  • the outer needle support tube 331 is made of, for example, a soft resin
  • the branch tube 332 is made of, for example, a hard resin.
  • the outer needle support tube 331 is formed, for example, such that it is easy to curve but difficult to expand and contract.
  • the rear end of the outer needle 310 is integrally connected to the front end of the outer needle support tube 331 so that the openings are in communication with each other.
  • the needle body 321 of the inner needle 320 is inserted into the outer needle 310, and the front end force of the outer needle 3 10 projects from the front end of the inner needle 320. .
  • the guide wire 322 passes through the outer needle support pipe 331 and the branch pipe 332 of the tubular member 330, and the rear end opening force of the branch pipe 332 also protrudes.
  • a packing 333 made of, for example, silicone resin is attached as an elastic member.
  • a guide wire 322 passes through the knockin 333.
  • the packing 333 opens the rear end of the branch pipe 332 due to its own elasticity, whether the inner needle 320 is penetrated as shown in FIG. 1A or the inner needle 320 is pulled out as shown in FIG. 1B. Seal it.
  • the cover member 340 has a bellows structure that can expand and contract in the front-rear direction, and the inner needle 320 is disposed therein.
  • the inner needle 320 and the cover member 340 are fixed at the rear end.
  • the rear end portion of the cover member 340 is formed as a knob-like portion 3 41 that can be easily gripped.
  • the front end portion 342 of the cover member 340 is formed in a cylindrical shape, and is detachably attached to the rear end opening of the branch pipe 332. That is, the cover member 340 has a structure in which the front end portion 342 and the knob-shaped portion 341 that are difficult to expand and contract are integrally formed on the front and rear of the expandable bellows portion 343.
  • the cover member 340 is formed so as to be longer than the length of the inner needle 320 in the extended state. Therefore, in a state where the cover member 340 is extended and the inner needle 320 is separated from the tubular member 330 together with the force bar member 340, the entire inner needle 320 is accommodated inside the cover member 340. In other words, as shown in FIG. 1A, in the indwelling needle 300 in the shipped state, the cover member 340 is compressed to the length of the inner needle 320 protruding rearward from the tubular member 330.
  • the cover member 340 is formed of an elastic material such as silicone resin, if the cover member 340 is left as it is, the compression state force is also expanded due to the elasticity of the force bar member 340 itself. Therefore, in the indwelling needle 300 of this embodiment, in order to pull out the inner needle 320 from the rear end of the outer needle 310, the rear of the cover member 340 is removed.
  • the force required to move the end (extending the cover member 340) is C
  • the force acting on the inner needle 320 by the compressed cover member 340 is D
  • the inner needle 320 is held by the frictional force between the outer needle 310 and the packing 333. In order to pull out, a force exceeding at least this frictional force is required. This force corresponds to the above-mentioned force.
  • the force force that the cover member 340 tries to expand is exerted on the fixed portion of the inner needle 320 with the cover member 340 by the compressed cover member 340 as the force D described above.
  • the dimensions, materials, surface treatment, etc. of each part are determined so that the above-mentioned forces C and D satisfy “C> D”.
  • the branch pipe 332 of the tubular member 330 is formed in a so-called bifurcated structure, and a branch portion 335 that extends rearward is also formed in the body. Yes.
  • the branch portion 335 has an inlet opening as an opening communicating with the inside of the branch pipe 332, and the tip of the extension tube 350 is integrally connected thereto by a joint 351.
  • the extension tube 350 is also bifurcated.
  • the contrast syringe 200C is detachably attached to one end of the extension tube 350
  • the physiological saline syringe 200P is detachably attached to the other end.
  • the tubular member 330 and the extension tube 350 are filled with physiological saline at the time of shipment, and a sealing cap (not shown) is detachable at the end of the extension tube 350. (Separable) is installed.
  • the extension tube 350 is provided with an exhaust valve (not shown) as a bubble removing means at a predetermined position! Speak.
  • the operator places the liquid injector 100 near the imaging unit 401 of the MRI apparatus 400 as shown in FIG. Prepare the contrast syringe 200C, the physiological saline syringe 200P, the indwelling needle 300, etc. to be used.
  • the sealing cap is removed from the two ends of the extension tube 350, and the contrast syringe 200C and the saline syringe 20 are respectively attached to the two ends.
  • OP is concatenated.
  • the inside of the indwelling needle 300 is filled with physiological saline in advance including the extension tube 350. Therefore, when the contrast syringe 200C and the physiological saline syringe 200P are connected to the extension tube 350, air does not exist inside the contrast syringe 200C, the physiological saline syringe 200P, and the indwelling needle 300.
  • indwelling needle 300 of the present embodiment has a flow path 323 that connects the tip of inner needle 321 and the inside of tubular member 330 in needle body 321; It is also possible to perform air venting while the inner needle 321 is not pulled out from the outer needle 310 punctured to).
  • the outer needle 310 and the inner needle 320 of the indwelling needle 300 are placed in the blood vessel of the subject in a state where there is no air inside the contrast syringe 200C, the saline syringe 200P, and the indwelling needle 300. Punctured. Thereafter, the knob-shaped portion 341 is pulled out, and the inner needle 320 is pulled out from the outer needle 310 and the tubular member 330.
  • the drug solution injector 100 slightly retracts the piston member 220 of the physiological saline syringe 200P by the saline injection mechanism 117P while the piston member 220 of the contrast syringe 200C is fixed by the contrast injection mechanism 117C.
  • the contrast medium and physiological saline are sequentially injected into the blood vessel of the subject by the chemical solution injection device 100, and a fluoroscopic image is taken by the subject MRI device 400.
  • the contrast agent and physiological saline pass through the extension tube 350, the tubular member 330, and the outer needle 320 in this order. Injected into the blood vessels.
  • bubbles may enter when connecting the contrast syringe 200C and the physiological saline syringe 200P to the indwelling needle 300 as described above. The bubbles are excluded to the outside by the exhaust valve of the indwelling needle 300. .
  • the indwelling needle 300 of this embodiment when the inner needle 320 is pulled out from the outer needle 310 and the tubular member 330 punctured by the subject as described above, the indwelling needle 300 is compressed as shown in FIG. 1B.
  • the cover member 340 is stretched due to its elasticity, and the entire pulled out inner needle 320 is accommodated. It is.
  • the operator removes the cover member 340 from the tubular member 330 and discards the inner needle 320 accommodated in the cover member 340. Therefore, it is possible to prevent secondary infection from occurring when the inner needle 320 is punctured by an operator.
  • the cover member 340 is naturally stretched by its own elasticity and the entire inner needle 320 is Automatically accommodated. Therefore, a dedicated work for accommodating the inner needle 320 in the force bar member 340 is necessary.
  • the cover member 340 maintains the state in which the inner needle 320 is accommodated, for example, the inner needle 320 is exposed even when the front end of the cover member 340 is located above or below. There is nothing wrong. For this reason, an operator does not contact the inner needle 320 to which the blood of the subject has adhered, and the inner needle 320 can be discarded easily and safely.
  • the inner needle 320 has a needle body 321 which is hard only at the front end, and most of the inner needle 320 is formed of a flexible guide wire 322.
  • the entire inner needle 320 is accommodated in the flexible cover member 340.
  • the guide wire 322 of the inner needle 320 can be wound together with the cover member 340 and discarded (not shown).
  • the rear end opening of the tubular member 330 from which the inner needle 320 has been pulled out is automatically closed by the packing 333, so that the blood of the subject can be prevented from adhering to the worker.
  • production can be prevented favorably.
  • the outer needle 310 is punctured into the blood vessel of the subject. In this state, it is not necessary to connect the extension tube 350 to the tubular member 330, and the work is easy.
  • extension tube 350 and the tubular member 330 are pre-filled with physiological saline as a chemical solution, and the extension tube 350 is equipped with an exhaust valve that eliminates liquid force bubbles, When the needle 300 is connected to the blood vessel of the subject, bubbles can be easily removed from the inside.
  • the end of the extension tube 350 is formed in a bifurcated structure, the contrast syringe 200C and the physiological saline syringe 200P can be simultaneously connected to the indwelling needle 300. Therefore, it is possible to reliably inject the contrast medium and physiological saline into the blood vessel of the subject with a simple structure, and contribute to the imaging of the fluoroscopic image with the MRI apparatus 400.
  • the cover member 340 is formed of an elastic material in which the compression state force is also elastically stretched, and the force C required for pulling out the inner needle 320 and the cover member 340 in the compression state In the relationship with the force D acting on the inner needle 320, it is exemplified that “C> D” is satisfied.
  • the cover member 501 is formed so as to maintain the compressed state and the expanded state by plastic deformation or the like. It is necessary to separate the force A required to extend the cover member 501 by pulling the rear end of the cover member 501 rearward, and the rear end opening force of the tubular member 505 from the front end portion 502 of the cover member 501. Between force B,
  • the above-described force A is a force required to separate the front end and the rear end in order to place the cover member 501 in a compressed state, and the force B is sufficient to separate the cover member 501 from the tubular member 505.
  • the cover member 501 In the indwelling needle 500 having the cover member 501 formed to maintain the compressed state and the stretched state, it is ensured that the cover member 501 is separated from the tubular member 505 after being extended to the limit. For this purpose, it is preferable to form irregularities 503 and 506 that spontaneously engage with each other on the rear end portion of the tubular member 505 and the front end portion 502 of the cover member 501.
  • the cover member 501 that maintains the compressed state and the expanded state can be formed of, for example, a material and a structure equivalent to a commercially available straw having a bellows structure.
  • the front end portion 342 of the cover member 340 is formed in a simple cylindrical shape, and the tip of the inner needle 320 accommodated in the cover member 340 is positioned behind the through hole of the front end portion 342.
  • the front end portion 502 of the cover member 501 is used as an elastic member that inertially closes the through hole when the inner needle 320 is accommodated in the cover member 501. It is also possible to form it. In this case, it is possible to more reliably prevent the inner needle 320 accommodated in the force bar member 501 from being exposed, so that the inner needle 320 can be discarded more safely.
  • the inner needle 320 is present on the front end portion 512 on the rear surface of the front end portion 512 of the cover member 511.
  • the one-way valve 513 can be integrally formed by automatically opening the through hole of the front end portion 512 by opening the through hole and accommodating the inner needle 320 in the cover member 511.
  • Such a one-way valve 513 can be realized, for example, by integrally forming a thin film swingable in the front-rear direction on the rear surface of the front end portion 512 having a through-hole formed in the front-rear direction.
  • packing 333 which is an elastic member, is mounted on the rear end opening of tubular member 330. It is illustrated that the through-hole of the packing 333 is inertially sealed when the inner needle 320 is pulled out. However, like the indwelling needle 510 illustrated in FIGS. 6A and 6B, the inner needle 320 is opened at the rear end opening of the tubular member 515 in a state where the inner needle 320 exists in the tubular member 515, and the inner needle 320 is One-way valve 516 may be mounted which is closed by being pulled out of the valve.
  • a manual valve 522 that can be opened and closed manually is attached to the tip portion 342 of the cover member 521.
  • the inner needle 320 is inserted through the opened manual valve 522, and the inner needle 320 is accommodated in the cover member 521 as shown in FIG.
  • the manual valve 522 is preferably closed by operation.
  • a manual valve 526 is attached to the rear end opening of the tubular member 525, and as shown in Fig. 7A, the inner needle 320 is inserted through the opened manual valve 526, as shown in Fig. 7B.
  • the manual valve 526 can be closed by pulling the inner needle 320 and manually operating the operating lever 527.
  • a sealing cap 531 to be attached to the front end portion 342 of the cover member 340 is prepared, and as shown in FIG. It is also possible to attach a sealing cap 531 to the front end portion 342 of the accommodated cover member 340.
  • Such a sealing cap 531 is preferably connected to the force bar member 340 with a flexible lead 532 as shown in the figure.
  • a sealing cap 535 to be attached to the rear end opening of the tubular member 330 is prepared, and as shown in FIG. 8B, the inner needle 320 is pulled out and the force is also manually applied to the rear end opening of the tubular member 330. It is also possible to attach a sealing cap 535.
  • Such a sealing cap 535 is also preferably connected to the tubular member 330 or the like with a flexible lead 536.
  • the rear end opening and extension of the tubular member 330 into which the inner needle 320 is inserted An example in which the inlet to which the tube 350 is connected is formed separately.
  • the tubular member 541 into which the inner needle 320 is inserted is used as an inlet and the extension tube 350 is connected thereto. It may be configured.
  • an automatic valve 545 that is closed when the inner needle 320 force S is pulled out and is closed when the extension tube 250 is not connected, and opened by the extension tube 350 being connected,
  • the tubular member 330 may be attached to the rear end opening.
  • Such an automatic valve 545 is, for example, press-fitted into the through-hole of the packing 542 by being pushed and moved by the joint 548 of the extension tube 350 and the packing 546 that is inertially closed when the inner needle 320 is pulled out. And an insertion tube 547.
  • the one-way valve 516 or the manual valve 511 may be attached to the rear end opening of the indwelling needle 540 or the branching portion 335 of the indwelling needle 300 or the like instead of the automatic valve 545.
  • These plural valves may be mounted in combination.
  • various closing means such as the indwelling needles 300 and 540 described above can be used in combination.
  • a tubular member that is automatically closed by packing or a cover member may be provided with a sealing cap. Yes.
  • the automatic valve 545 as described above is attached to the inlet of the branching portion 335 of the indwelling needle 300 described above, and the extension tube 350 may be detachably attached thereto! ⁇ .
  • the exhaust valve which is the bubble removing means is provided in the extension tube 350.
  • such an exhaust valve may be provided in the tubular member.
  • the entire cover member 340 is illustrated as having a bellows structure.
  • the cover member 551 includes the hard cover 552 and the bellows.
  • a cover 553 may be included.
  • the hard cover 552 and the bellows cover 553 are connected to each other at their front end portions, and the rear portion of the hard cover 552 is located inside the bellows cover 553.
  • the hard cover 552 has the same total length as the needle body 321 of the inner needle 320. As a result, the hard needle body 321 can be reliably covered with the hard cover 552. Furthermore, the bellows cover 553 extends to the full length equivalent to the total of the inner needle 320 and the guide wire 322. The flexible guide wire 322 can be covered with the flexible bellows cover 553, and the whole can be rolled in this covered state.
  • the hard cover 552 has the inner needle 320 as the outer needle 310 and the tubular member 330. It should be long enough to cover at least the front end of the needle body 321 when pulled out of the needle body.
  • the hard force bar 562 of the cover member 561 may be slidably mounted inside the front end of the bellows cover 563!
  • the maximum force E required to slide the hard cover 562 against the bellows cover 563, the guide wire 322 and the inner needle 321 and the force F required to extend the bellows cover 563 are F.
  • the force G required to separate the hard cover 562 from the tubular member 330 is F.
  • the hard cover 562 is tubular with the inner needle 321 positioned inside the hard cover 562 and the guide wire 322 positioned inside the bellows cover 563. Separated from member 330. Therefore, with this indwelling needle 560, the hard needle body 321 can be reliably covered with the hard cover 562, and the flexible guide carrier 322 can be covered with the flexible bellows cover 563.
  • the hard cover 562 has a length sufficient to cover at least the front end portion of the needle body 321 when the inner needle 320 is pulled out from the outer needle 310 and the tubular member 330.
  • the extension tube 350 of the indwelling needle 300 has a bifurcated structure, and the contrast syringe 200C and the physiological saline syringe 200P are attached simultaneously.
  • the end may not be branched and only one of the contrast syringe 200C or the physiological saline syringe 200P may be attached, or the end may be branched into three or more, and three or more kinds of chemical syringes May be mounted.
  • the indwelling needle 300 may be prefilled with a contrast medium as a chemical solution.
  • the contrast syringe 200C and the physiological saline syringe 200P are detachably attached to the bifurcated ends of the extension tube 350 of the indwelling needle 300.
  • the contrast syringe 200C and the physiological saline 200P may be attached to the body at the end of the extension tube 350.
  • the extension tube 350 exemplifying that the extension tube 350 is connected to the tubular member 330 of the indwelling needle 300 is configured to be connected to the tubular member 330.
  • the tubular member 330 is exemplified as having the flexible outer needle support tube 331 and the hard branch tube 332.
  • the tubular member may be composed of only a hard member.
  • the inner needle 320 may be formed of the hard needle body 321 and the flexible guide wire 322, and the force inner needle may be composed of only the hard needle body! /.
  • the inner needle 320 may be a solid needle, for example, a force exemplified as being formed as the inner needle 320 hollow needle. Further, in the above embodiment, a force exemplifying a structure in which the outer needle 310 and the tube member 331 are simply connected. For example, a so-called wing or grip may be attached to the connecting part.
  • the MRI apparatus 400 is used as the fluoroscopic imaging apparatus, and the liquid injector 100 injects the MR contrast agent.
  • the fluoroscopic imaging apparatus a computed tomography (CT) ) Scanner, PET (Positron Emission Tomography) equipment, Ultrasonic diagnostic equipment, Angio equipment, MRA (MR)
  • CT computed tomography
  • PET PET
  • Ultrasonic diagnostic equipment Angio equipment
  • MRA MRA
  • the indwelling needle of the present invention can also be applied to the case where the chemical solution injection device injects a contrast agent for the use of an Angio) device.
  • each part such as the chemical liquid injector 100 has been specifically described.
  • the drive source of the piston drive mechanism 117 may be a 0 0 (; t Current) motor or an AC (Alternating Current) motor
  • the display panel 104 may be an organic EL (Electro-Luminescence) display or a plasma display. Good.
  • each means of the chemical injection device 100 is logically realized.
  • each of these means may be configured with unique hardware, or a part may be stored as software in the RAM 143, and a part may be configured as node software.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un dispositif d'injection de liquide médicamenteux qui a une aiguille externe (310), une aiguille interne (320), un élément tubulaire (330), et un élément couvercle (340). L'aiguille externe (310) est souple et au moins sa partie avant est laissée dans le vaisseau sanguin. L'aiguille interne (320), dure à sa partie avant, est placée dans l'aiguille externe (310), et introduite dans le vaisseau sanguin. L'élément tubulaire (330) est relié solidaire au niveau de l'ouverture de son extrémité avant à l'extrémité arrière de ladite aiguille externe (310), et la partie arrière de l'aiguille interne (320) saille d'une ouverture d'extrémité arrière de l'élément tubulaire (330). L'élément couvercle (340) présente une structure de soufflet extensible qui peut s'étendre d'une longueur telle qu'il puisse recevoir toute l'aiguille interne (320). L'extrémité arrière de l'élément couvercle (340) est fixée séparément à l'ouverture de l'extrémité arrière de l'élément tubulaire.
PCT/JP2006/318060 2005-09-12 2006-09-12 Dispositif d'injection de liquide medicamenteux WO2007032343A1 (fr)

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Cited By (19)

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EP2272432A1 (fr) * 2007-05-07 2011-01-12 Vascular Pathways Inc. Dispositif d'insertion de cathéter intraveineux et d'échantillonage sanguin et procédé d'utilisation
US9522254B2 (en) 2013-01-30 2016-12-20 Vascular Pathways, Inc. Systems and methods for venipuncture and catheter placement
US9616201B2 (en) 2011-01-31 2017-04-11 Vascular Pathways, Inc. Intravenous catheter and insertion device with reduced blood spatter
US9861792B2 (en) 2011-02-25 2018-01-09 C. R. Bard, Inc. Medical component insertion device including a retractable needle
US9872971B2 (en) 2010-05-14 2018-01-23 C. R. Bard, Inc. Guidewire extension system for a catheter placement device
US9950139B2 (en) 2010-05-14 2018-04-24 C. R. Bard, Inc. Catheter placement device including guidewire and catheter control elements
US10220191B2 (en) 2005-07-06 2019-03-05 Vascular Pathways, Inc. Intravenous catheter insertion device and method of use
US10232146B2 (en) 2014-09-05 2019-03-19 C. R. Bard, Inc. Catheter insertion device including retractable needle
US10384039B2 (en) 2010-05-14 2019-08-20 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components
US10426931B2 (en) 2010-05-14 2019-10-01 C. R. Bard, Inc. Catheter placement device and method
US10493262B2 (en) 2016-09-12 2019-12-03 C. R. Bard, Inc. Blood control for a catheter insertion device
USD903100S1 (en) 2015-05-01 2020-11-24 C. R. Bard, Inc. Catheter placement device
USD903101S1 (en) 2011-05-13 2020-11-24 C. R. Bard, Inc. Catheter
USD921884S1 (en) 2018-07-27 2021-06-08 Bard Access Systems, Inc. Catheter insertion device
US11040176B2 (en) 2015-05-15 2021-06-22 C. R. Bard, Inc. Catheter placement device including an extensible needle safety component
US11389626B2 (en) 2018-03-07 2022-07-19 Bard Access Systems, Inc. Guidewire advancement and blood flashback systems for a medical device insertion system
US11400260B2 (en) 2017-03-01 2022-08-02 C. R. Bard, Inc. Catheter insertion device
US11559665B2 (en) 2019-08-19 2023-01-24 Becton, Dickinson And Company Midline catheter placement device
US11925779B2 (en) 2010-05-14 2024-03-12 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components

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US10220191B2 (en) 2005-07-06 2019-03-05 Vascular Pathways, Inc. Intravenous catheter insertion device and method of use
US11925778B2 (en) 2005-07-06 2024-03-12 Vascular Pathways, Inc. Intravenous catheter insertion device
US11577054B2 (en) 2005-07-06 2023-02-14 Vascular Pathways, Inc. Intravenous catheter insertion device and method of use
US11020571B2 (en) 2005-07-06 2021-06-01 Vascular Pathways, Inc. Intravenous catheter insertion device and method of use
US10912930B2 (en) 2005-07-06 2021-02-09 Vascular Pathways, Inc. Intravenous catheter insertion device and method of use
US10806906B2 (en) 2005-07-06 2020-10-20 Vascular Pathways, Inc. Intravenous catheter insertion device and method of use
US8986227B2 (en) 2007-04-18 2015-03-24 Vascular Pathways, Inc. Intravenous catheter insertion and blood sample devices and method of use
US9675784B2 (en) 2007-04-18 2017-06-13 Vascular Pathways, Inc. Intravenous catheter insertion and blood sample devices and method of use
US9757540B2 (en) 2007-04-18 2017-09-12 Vascular Pathways, Inc. Intravenous catheter insertion and blood sample devices and method of use
US10799680B2 (en) 2007-05-07 2020-10-13 Vascular Pathways, Inc. Intravenous catheter insertion and blood sample devices and method of use
US10525236B2 (en) 2007-05-07 2020-01-07 Vascular Pathways, Inc. Intravenous catheter insertion and blood sample devices and method of use
US10086171B2 (en) 2007-05-07 2018-10-02 Vascular Pathways, Inc. Intravenous catheter insertion and blood sample devices and method of use
US8721546B2 (en) 2007-05-07 2014-05-13 Vascular Pathways, Inc. Intravenous catheter insertion and blood sample devices and method of use
EP2272432A1 (fr) * 2007-05-07 2011-01-12 Vascular Pathways Inc. Dispositif d'insertion de cathéter intraveineux et d'échantillonage sanguin et procédé d'utilisation
US10426931B2 (en) 2010-05-14 2019-10-01 C. R. Bard, Inc. Catheter placement device and method
US10384039B2 (en) 2010-05-14 2019-08-20 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components
US11000678B2 (en) 2010-05-14 2021-05-11 C. R. Bard, Inc. Catheter placement device and method
US11135406B2 (en) 2010-05-14 2021-10-05 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components
US11278702B2 (en) 2010-05-14 2022-03-22 C. R. Bard, Inc. Guidewire extension system for a catheter placement device
US10688280B2 (en) 2010-05-14 2020-06-23 C. R. Bard, Inc. Catheter placement device including guidewire and catheter control elements
US10688281B2 (en) 2010-05-14 2020-06-23 C. R. Bard, Inc. Catheter placement device including guidewire and catheter control elements
US10722685B2 (en) 2010-05-14 2020-07-28 C. R. Bard, Inc. Catheter placement device including guidewire and catheter control elements
US11925779B2 (en) 2010-05-14 2024-03-12 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components
US9872971B2 (en) 2010-05-14 2018-01-23 C. R. Bard, Inc. Guidewire extension system for a catheter placement device
US9950139B2 (en) 2010-05-14 2018-04-24 C. R. Bard, Inc. Catheter placement device including guidewire and catheter control elements
US9616201B2 (en) 2011-01-31 2017-04-11 Vascular Pathways, Inc. Intravenous catheter and insertion device with reduced blood spatter
US11202886B2 (en) 2011-01-31 2021-12-21 Vascular Pathways, Inc. Intravenous catheter and insertion device with reduced blood spatter
US10328239B2 (en) 2011-01-31 2019-06-25 Vascular Pathways, Inc. Intravenous catheter and insertion device with reduced blood spatter
US11931534B2 (en) 2011-02-25 2024-03-19 C. R. Bard, Inc. Medical component insertion device including a retractable needle
US11123524B2 (en) 2011-02-25 2021-09-21 C. R. Bard, Inc. Medical component insertion device including a retractable needle
US9861792B2 (en) 2011-02-25 2018-01-09 C. R. Bard, Inc. Medical component insertion device including a retractable needle
USD903101S1 (en) 2011-05-13 2020-11-24 C. R. Bard, Inc. Catheter
US10265507B2 (en) 2013-01-30 2019-04-23 Vascular Pathways, Inc. Systems and methods for venipuncture and catheter placement
US9522254B2 (en) 2013-01-30 2016-12-20 Vascular Pathways, Inc. Systems and methods for venipuncture and catheter placement
US11565089B2 (en) 2014-09-05 2023-01-31 C. R. Bard, Inc. Catheter insertion device including retractable needle
US11033719B2 (en) 2014-09-05 2021-06-15 C. R. Bard, Inc. Catheter insertion device including retractable needle
US10232146B2 (en) 2014-09-05 2019-03-19 C. R. Bard, Inc. Catheter insertion device including retractable needle
USD903100S1 (en) 2015-05-01 2020-11-24 C. R. Bard, Inc. Catheter placement device
US11040176B2 (en) 2015-05-15 2021-06-22 C. R. Bard, Inc. Catheter placement device including an extensible needle safety component
US11759618B2 (en) 2016-09-12 2023-09-19 C. R. Bard, Inc. Blood control for a catheter insertion device
US10493262B2 (en) 2016-09-12 2019-12-03 C. R. Bard, Inc. Blood control for a catheter insertion device
US11400260B2 (en) 2017-03-01 2022-08-02 C. R. Bard, Inc. Catheter insertion device
US11389626B2 (en) 2018-03-07 2022-07-19 Bard Access Systems, Inc. Guidewire advancement and blood flashback systems for a medical device insertion system
US12017020B2 (en) 2018-03-07 2024-06-25 Bard Access Systems, Inc. Guidewire advancement and blood flashback systems for a medical device insertion system
USD921884S1 (en) 2018-07-27 2021-06-08 Bard Access Systems, Inc. Catheter insertion device
US11559665B2 (en) 2019-08-19 2023-01-24 Becton, Dickinson And Company Midline catheter placement device
US11883615B2 (en) 2019-08-19 2024-01-30 Becton, Dickinson And Company Midline catheter placement device

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