WO2007009143A3 - Verfahren zur herstellung nebivolol - Google Patents
Verfahren zur herstellung nebivolol Download PDFInfo
- Publication number
- WO2007009143A3 WO2007009143A3 PCT/AT2006/000303 AT2006000303W WO2007009143A3 WO 2007009143 A3 WO2007009143 A3 WO 2007009143A3 AT 2006000303 W AT2006000303 W AT 2006000303W WO 2007009143 A3 WO2007009143 A3 WO 2007009143A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- producing
- separated
- nebivolol
- formula
- producing nebivolol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
Abstract
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2006272420A AU2006272420A1 (en) | 2005-07-19 | 2006-07-17 | Method for producing nebivolol |
US11/996,370 US20080221340A1 (en) | 2005-07-19 | 2006-07-17 | Process for the Production of Nebivolol |
BRPI0613610-9A BRPI0613610A2 (pt) | 2005-07-19 | 2006-07-17 | processo para preparação de nebivolol |
MX2008000747A MX2008000747A (es) | 2005-07-19 | 2006-07-17 | Metodo para producir nebivolol. |
CA002615832A CA2615832A1 (en) | 2005-07-19 | 2006-07-17 | Method for producing nebivolol |
JP2008521739A JP2009502750A (ja) | 2005-07-19 | 2006-07-17 | ネビボロールの製造方法 |
EA200800364A EA200800364A1 (ru) | 2005-07-19 | 2006-07-17 | Способ получения небиволола |
EP06760790A EP1919888A2 (de) | 2005-07-19 | 2006-07-17 | Verfahren zur herstellung nebivolol |
IL188777A IL188777A0 (en) | 2005-07-19 | 2008-01-15 | Method for producing nebivolol |
NO20080823A NO20080823L (no) | 2005-07-19 | 2008-02-15 | Fremgangsmate for fremstilling av nebivolol |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ATA1214/2005 | 2005-07-19 | ||
AT0121405A AT502220A1 (de) | 2005-07-19 | 2005-07-19 | Verfahren zur herstellung von nebivolol |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007009143A2 WO2007009143A2 (de) | 2007-01-25 |
WO2007009143A3 true WO2007009143A3 (de) | 2007-04-05 |
Family
ID=37450808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/AT2006/000303 WO2007009143A2 (de) | 2005-07-19 | 2006-07-17 | Verfahren zur herstellung nebivolol |
Country Status (15)
Country | Link |
---|---|
US (1) | US20080221340A1 (de) |
EP (1) | EP1919888A2 (de) |
JP (1) | JP2009502750A (de) |
KR (1) | KR20080027368A (de) |
CN (1) | CN101243062A (de) |
AT (1) | AT502220A1 (de) |
AU (1) | AU2006272420A1 (de) |
BR (1) | BRPI0613610A2 (de) |
CA (1) | CA2615832A1 (de) |
EA (1) | EA200800364A1 (de) |
IL (1) | IL188777A0 (de) |
MX (1) | MX2008000747A (de) |
NO (1) | NO20080823L (de) |
WO (1) | WO2007009143A2 (de) |
ZA (1) | ZA200800963B (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE533752T1 (de) | 2008-09-08 | 2011-12-15 | Cadila Pharmaceuticals Ltd | Verbesserter herstellungsprozess für nebivolol- hydrocholorid |
IT1395354B1 (it) * | 2009-07-23 | 2012-09-14 | Zach System Spa | Processo di preparazione di nebivololo |
DE102010005953A1 (de) | 2010-01-27 | 2011-07-28 | Corden PharmaChem GmbH, 68305 | Verfahren zur Herstellung von Nebivolol |
IT1397962B1 (it) * | 2010-02-11 | 2013-02-04 | Menarini Int Operations Lu Sa | Processo per la preparazione del nebivololo. |
CN102190647A (zh) * | 2010-03-12 | 2011-09-21 | 浙江海翔药业股份有限公司 | 一种奈比洛尔的中间体的制备方法 |
PL3299364T3 (pl) | 2015-05-19 | 2022-02-07 | Zhejiang Ausun Pharmaceutical Co., Ltd. | Sposób syntezy nebiwololu i jego związek pośredni |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0145067A2 (de) * | 1983-12-05 | 1985-06-19 | Janssen Pharmaceutica N.V. | 2,2'-Iminobisäthanol-Derivate |
CN1683355A (zh) * | 2005-03-03 | 2005-10-19 | 浙江医药股份有限公司新昌制药厂 | Dl-奈必洛尔及其盐酸盐的制备方法 |
-
2005
- 2005-07-19 AT AT0121405A patent/AT502220A1/de not_active Application Discontinuation
-
2006
- 2006-07-17 EA EA200800364A patent/EA200800364A1/ru unknown
- 2006-07-17 MX MX2008000747A patent/MX2008000747A/es not_active Application Discontinuation
- 2006-07-17 AU AU2006272420A patent/AU2006272420A1/en not_active Abandoned
- 2006-07-17 ZA ZA200800963A patent/ZA200800963B/xx unknown
- 2006-07-17 CA CA002615832A patent/CA2615832A1/en not_active Abandoned
- 2006-07-17 US US11/996,370 patent/US20080221340A1/en not_active Abandoned
- 2006-07-17 KR KR1020087001837A patent/KR20080027368A/ko not_active Application Discontinuation
- 2006-07-17 CN CNA2006800293627A patent/CN101243062A/zh active Pending
- 2006-07-17 BR BRPI0613610-9A patent/BRPI0613610A2/pt not_active IP Right Cessation
- 2006-07-17 JP JP2008521739A patent/JP2009502750A/ja active Pending
- 2006-07-17 WO PCT/AT2006/000303 patent/WO2007009143A2/de active Application Filing
- 2006-07-17 EP EP06760790A patent/EP1919888A2/de not_active Withdrawn
-
2008
- 2008-01-15 IL IL188777A patent/IL188777A0/en unknown
- 2008-02-15 NO NO20080823A patent/NO20080823L/no not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0145067A2 (de) * | 1983-12-05 | 1985-06-19 | Janssen Pharmaceutica N.V. | 2,2'-Iminobisäthanol-Derivate |
CN1683355A (zh) * | 2005-03-03 | 2005-10-19 | 浙江医药股份有限公司新昌制药厂 | Dl-奈必洛尔及其盐酸盐的制备方法 |
Non-Patent Citations (2)
Title |
---|
DATABASE WPI Week 200616, Derwent World Patents Index; AN 2006-146512, XP002410014 * |
JOHANNES, CHARLES W. ET AL: "Zr-Catalyzed Kinetic Resolution of Allylic Ethers and Mo-Catalyzed Chromene Formation in Synthesis. Enantioselective Total Synthesis of the Antihypertensive Agent (S,R,R,R)-Nebivolol", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , 120(33), 8340-8347 CODEN: JACSAT; ISSN: 0002-7863, 1998, XP002410010 * |
Also Published As
Publication number | Publication date |
---|---|
JP2009502750A (ja) | 2009-01-29 |
BRPI0613610A2 (pt) | 2011-01-18 |
NO20080823L (no) | 2008-04-02 |
EA200800364A1 (ru) | 2008-06-30 |
CN101243062A (zh) | 2008-08-13 |
AU2006272420A1 (en) | 2007-01-25 |
WO2007009143A2 (de) | 2007-01-25 |
IL188777A0 (en) | 2008-08-07 |
US20080221340A1 (en) | 2008-09-11 |
EP1919888A2 (de) | 2008-05-14 |
ZA200800963B (en) | 2009-08-26 |
AT502220A1 (de) | 2007-02-15 |
KR20080027368A (ko) | 2008-03-26 |
CA2615832A1 (en) | 2007-01-25 |
MX2008000747A (es) | 2008-04-14 |
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