WO2006065755A3 - Sels d'ammonium quaternaire d'amines heteroaromatiques fusionnees utilises comme nouveaux antagonistes du recepteur de l'acetylcholine muscarinique - Google Patents

Sels d'ammonium quaternaire d'amines heteroaromatiques fusionnees utilises comme nouveaux antagonistes du recepteur de l'acetylcholine muscarinique Download PDF

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Publication number
WO2006065755A3
WO2006065755A3 PCT/US2005/044951 US2005044951W WO2006065755A3 WO 2006065755 A3 WO2006065755 A3 WO 2006065755A3 US 2005044951 W US2005044951 W US 2005044951W WO 2006065755 A3 WO2006065755 A3 WO 2006065755A3
Authority
WO
WIPO (PCT)
Prior art keywords
amines
hetearomatic
fused
acetylcholine receptor
quaternary ammonium
Prior art date
Application number
PCT/US2005/044951
Other languages
English (en)
Other versions
WO2006065755A2 (fr
Inventor
Jakob Busch-Petersen
Roderick S Davis
Wei Fu
Jian Jin
Dramane I Laine
Michael R Palovich
Original Assignee
Glaxo Group Ltd
Jakob Busch-Petersen
Roderick S Davis
Wei Fu
Jian Jin
Dramane I Laine
Michael R Palovich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Jakob Busch-Petersen, Roderick S Davis, Wei Fu, Jian Jin, Dramane I Laine, Michael R Palovich filed Critical Glaxo Group Ltd
Publication of WO2006065755A2 publication Critical patent/WO2006065755A2/fr
Publication of WO2006065755A3 publication Critical patent/WO2006065755A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'invention concerne de nouveaux dérivés d'amines cycliques, des compositions pharmaceutiques, des procédés pour leur préparation ainsi que leur utilisation dans le traitement de maladies médiées par le récepteur de l'acétylcholine muscarinique.
PCT/US2005/044951 2004-12-13 2005-12-13 Sels d'ammonium quaternaire d'amines heteroaromatiques fusionnees utilises comme nouveaux antagonistes du recepteur de l'acetylcholine muscarinique WO2006065755A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63566404P 2004-12-13 2004-12-13
US60/635,664 2004-12-13

Publications (2)

Publication Number Publication Date
WO2006065755A2 WO2006065755A2 (fr) 2006-06-22
WO2006065755A3 true WO2006065755A3 (fr) 2006-10-12

Family

ID=36588443

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/044951 WO2006065755A2 (fr) 2004-12-13 2005-12-13 Sels d'ammonium quaternaire d'amines heteroaromatiques fusionnees utilises comme nouveaux antagonistes du recepteur de l'acetylcholine muscarinique

Country Status (1)

Country Link
WO (1) WO2006065755A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200519108A (en) 2003-07-17 2005-06-16 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
AR046103A1 (es) 2003-10-14 2005-11-23 Glaxo Group Ltd Compuesto de 8-azoniabiciclo [3.2.1] octano,composicion farmaceutica para el tratamiento de enfermedades mediadas por receptores de acetilcolina muscarinicos y uso del compuesto para preparar dicha composicion
MXPA06004242A (es) 2003-10-17 2006-06-28 Glaxo Group Ltd Antagonistas del receptor muscarinico de la acetilcolina.
PE20050489A1 (es) 2003-11-04 2005-09-02 Glaxo Group Ltd Antagonistas de receptores de acetilcolina muscarinicos
JP2007529513A (ja) 2004-03-17 2007-10-25 グラクソ　グループ　リミテッド Ｍ３ムスカリン性アセチルコリン受容体アンタゴニスト
MY144753A (en) 2004-04-27 2011-10-31 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
WO2005112644A2 (fr) 2004-05-13 2005-12-01 Glaxo Group Limited Antagonistes récepteurs d'acétyle choline muscarinique
WO2006055553A2 (fr) 2004-11-15 2006-05-26 Glaxo Group Limited Nouveaux antagonistes des recepteurs muscariniques de type m3 de l'acetylcholine
JP2009504768A (ja) 2005-08-18 2009-02-05 グラクソ グループ リミテッド ムスカリン性アセチルコリン受容体アンタゴニスト
CN101730699A (zh) 2007-03-21 2010-06-09 百时美施贵宝公司 可用于治疗增殖性、变应性、自身免疫性和炎症性疾病的稠合杂环化合物
CL2009000248A1 (es) 2008-02-06 2009-09-11 Glaxo Group Ltd Compuestos derivados de pirazolo [3,4-b] piridin-5-il, inhibidores de la fosfodiesterasa de tipo iv (pde4) y antagonista de receptores muscarinicos de acetilcolina (machr); composicion farmaceutica que los comprende; y su uso en la preparacion de medicamentos utiles en el tratamiento de enferemedades respiratorias y alergicas
UY31637A1 (es) 2008-02-06 2009-08-03 Farmacoforos duales-antagonistas muscarinicos de pde4
PE20091563A1 (es) 2008-02-06 2009-11-05 Glaxo Group Ltd Farmacoforos duales - antagonistas muscarinicos de pde4
WO2010094643A1 (fr) 2009-02-17 2010-08-26 Glaxo Group Limited Dérivés de quinoline et applications associées dans la rhinite et l'urticaire
AU2012329098B2 (en) 2011-10-26 2017-08-03 Allergan, Inc. Amide derivatives of N-urea substituted amino acids as formyl peptide receptor like-1 (FPRL-1) receptor modulators
CN104302630A (zh) 2012-04-16 2015-01-21 阿勒根公司 作为甲酰肽受体2调节剂的(2-脲基乙酰氨基)烷基衍生物
TW201414737A (zh) 2012-07-13 2014-04-16 必治妥美雅史谷比公司 作爲激酶抑制劑之咪唑并三□甲腈
CA2899804A1 (fr) 2013-03-06 2014-09-12 Allergan, Inc. Utilisation d'agonistes du recepteur 2 de peptide formyle pour le traitement de maladies dermatologiques
KR102290134B1 (ko) 2013-03-06 2021-08-17 알러간, 인코포레이티드 안구 염증성 질환을 치료하기 위한 포르밀 펩타이드 수용체 2의 작용제의 용도

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006065788A2 (fr) * 2004-12-13 2006-06-22 Glaxo Group Limited Nouveaux antagonistes du recepteur muscarinique de l'acetylcholine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006065788A2 (fr) * 2004-12-13 2006-06-22 Glaxo Group Limited Nouveaux antagonistes du recepteur muscarinique de l'acetylcholine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE CAS [online] accession no. STN Database accession no. (2006:605213) *

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Publication number Publication date
WO2006065755A2 (fr) 2006-06-22

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