WO2005096956A1 - Fil chirurgical - Google Patents

Fil chirurgical Download PDF

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Publication number
WO2005096956A1
WO2005096956A1 PCT/SG2005/000104 SG2005000104W WO2005096956A1 WO 2005096956 A1 WO2005096956 A1 WO 2005096956A1 SG 2005000104 W SG2005000104 W SG 2005000104W WO 2005096956 A1 WO2005096956 A1 WO 2005096956A1
Authority
WO
WIPO (PCT)
Prior art keywords
thread
clear section
surgical
surgical thread
point
Prior art date
Application number
PCT/SG2005/000104
Other languages
English (en)
Inventor
Tze Liang Woffles Wu
Original Assignee
Tze Liang Woffles Wu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/850,480 external-priority patent/US7601164B2/en
Priority to MXPA06011576A priority Critical patent/MXPA06011576A/es
Priority to DE602005023590T priority patent/DE602005023590D1/de
Priority to BRPI0508782-1A priority patent/BRPI0508782B1/pt
Priority to AT05722351T priority patent/ATE481036T1/de
Priority to EP05722351A priority patent/EP1734870B1/fr
Application filed by Tze Liang Woffles Wu filed Critical Tze Liang Woffles Wu
Priority to AU2005230815A priority patent/AU2005230815B2/en
Priority to JP2007507282A priority patent/JP4890440B2/ja
Priority to TW094110926A priority patent/TWI375574B/zh
Priority to MYPI20051548A priority patent/MY144385A/en
Priority to US11/123,214 priority patent/US8236027B2/en
Publication of WO2005096956A1 publication Critical patent/WO2005096956A1/fr
Priority to HK07104201.0A priority patent/HK1096567A1/xx
Priority to AU2010212524A priority patent/AU2010212524B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166Sutures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00792Plastic surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166Sutures
    • A61B2017/06176Sutures with protrusions, e.g. barbs

Definitions

  • the present invention relates generally to a surgical thread for use in plastic surgery operations and a method of performing plastic surgery operations using the surgical thread.
  • a surgical thread for plastic surgery operations comprising a clear section and multiple sharp projections on either side of the clear section, wherein the clear section is devoid of projections, and the projections on both sides of the clear section are inclined toward the clear sectio .
  • a method of performing plastic surgery operations using a surgical thread having a clear section and multiple sharp projections on either side of the clear section, wherein the clear section is devoid of projections, and the projections on both sides of the clear section are inclined toward the clear section including: making an incision into tissue at an entry point defining the point of tissue lift; inserting a cannula in a first pass subcutaneously between the entry point and a first exit point from where tissue is to be suspended; threading one end of the surgical thread from the entry point through the cannula and out of the first exit point until the clear section nears or enters the incision; removing the cannula and reinserting the cannula in a second pass between the entry point and a second exit point spaced from the first exit point; threading the other end of the surgical thread through the cannula and out of the second exit point thereby folding the thread back on itself; removing the cannula and adjusting the thread tension from both ends of the thread to achieve a desired lift
  • Figure 1 is a side view of a surgical thread according to an embodiment of the present invention
  • Figure 2 is an enlarged view of a section of the surgical thread in one embodiment of the invention
  • Figure 3A illustrates a first step in a face lift procedure according to an embodiment of the present invention
  • Figure 3B illustrates a second step in the surgical procedure
  • Figure 3C illustrates a third step in the surgical procedure
  • Figure 4 illustrates a second embodiment of the surgical thread
  • Figure 5 illustrates the surgical thread of Figure 4 threaded through a person's face
  • Figure 6 illustrates various locations of performing a surgical procedure on a person' s face according to an embodiment of the invention .
  • Figure 7A is an enlarged view of a section of the surgical thread in another embodiment of the invention.
  • Figure 7B is an enlarged view of a section of the surgical thread in yet another embodiment of the invention .
  • the drawings illustrate surgical threads and methods of performing operations with the surgical thread which produce an improved soft tissue lift capable of sustaining a longer lift than that achievable with known surgical threads and face lift procedures.
  • Figure 1 illustrates a length of surgical thread 10 for use in surgical procedures, and in particular plastic and cosmetic surgery.
  • the thread 10 can be made of any soft, resilient and bio-compatible material.
  • the thread material is made of polypropylene but it is also envisaged that other suitable materials could include gold, stainless steel and dissolvable suture materials such as polydiaxonone .
  • the thread may be made of varying grades and thicknesses of these materials, depending on the area being lifted and on the desired effect. In this embodiment the thread thickness is between a 3.0 gauge (0.3mm diameter) and a 2.0 gauge (0.35mm diameter) suture.
  • FIG. 1 On either side of the clear zone 14 are barb sections 16 where the surface of the thread is provided with barbs 12.
  • the barbs 12 are inclined relative to the thread such that when inserted into soft tissues the barbs allow the thread to be pulled with ease through the tissue in one direction but resist pulling, or unthreading, of the thread in the opposite direction by digging their sharp ends into the surrounding soft tissue in resistance.
  • the inclination of the barbs in the two barb sections 16 on either side of the clear zone 14 are oriented in opposite directions .
  • Figure 2 shows in an enlarged view the clear zone 14 and barb zones 16 on either side of the clear zone .
  • the barbs 12 to the left of the clear zone 14 are inclined towards the right hand side of the figure, whereas the barbs 12 to the right of the clear zone 14 are inclined in the opposite direction to the left hand side of the figure.
  • the barbs in both barb zones are all pointing towards the clear zone 14.
  • the barbs are created by cutting or etching into the surface of the surgical thread 10 in a manner to produce a sharp tip 18 of the barb 12.
  • the barbs are furthermore spaced around the surgical thread in a spiral formation. This can be seen in Figure 2.
  • the spiral nature of the barbs means that when the surgical thread is threaded subcutaneously through soft tissue the thread is able to achieve a better hold on the surrounding tissue in all directions.
  • End zones 20 are located at the ends of the surgical thread and next to barb zones 16. End zones 20 are also devoid of barbs 12.
  • the barbs are spaced at intervals of about 1 to 2mm.
  • One 360° spiral revolution spans about approximately 35 to 45mm.
  • Approximately 18 to 22 barbs are contained in one spiral revolution. Therefore, a barbed zoned 20cm in length contains about 5 spirals.
  • Each barb is 1 to 2mm long and occupies 1/6 to 1/4 the thickness of the thread.
  • the above dimensions are illustrative of a working embodiment of the surgical thread but are not to be considered in a restrictive manner.
  • the length of the surgical thread may vary from short to long depending on the area and amount of soft tissue to be lifted. In other words, a short lift (e.g. eyebrow lift) would require a shorter surgical thread than a longer lift (e.g. chin lift).
  • Variations to the above preferred dimensions while retaining the concept of the surgical thread are possible.
  • the barb revolutions may be quite tight with only 4 to 6 barbs per revolution.
  • the spacing between barbs may vary, or the barb lengths themselves may be shorter or longer, depending on the precise end use of the thread and limitations of the manufacturing equipment .
  • the present surgical thread 10 is used in a manner to create a "sling" effect on the tissue portion to be lifted by the surgery .
  • the thread is intended to be doubled back on itself with the clear zone 14 defining the fold and engaging the portion of tissue to be lifted. Accordingly, rather than the tissue being lifted at a single point defined by the end of the threads , as currently known, the present thread lifts , or takes hold of, more tissue by using the sling created by the looped fold to lift the tissue, resulting in a more secure and reliable lift.
  • end zones 20 are not, however, burdened with bearing the entire load of the lift. Owing to the distribution of inclined barbs along the embedded length of the surgical thread 10 the load is evenly borne against gravity along the thread length in a self retaining manner.
  • Figure 3A to 3C illustrate a surgical technique in conducting a mid face suspension, or brow lift, on a person's face.
  • a surgeon first assesses the degree of slack in the pre-operational face and decides on the desired shape of the cheek or mid face area. The surgeon then marks the patient' s skin identifying the point that will be lifted and the position of the two anchor points higher up the face from where the lift will be supported.
  • the surgeon After administering to the patient local anesthetic blocks and local infiltration, the surgeon makes a small stab incision in the soft tissue at the lift point defining the entry point 30 as illustrated in Figure 3A. Bluntly dissecting the stab incision the surgeon creates a space at the entry point 30 subcutaneously of about 0.5cm radially around the stab incision. By creating this space dimpling in the post operative period is avoided.
  • a cannula 32, or insertion needle is next introduced into the entry point 30 and threaded in a first pass 25 through the soft tissue and/or muscle under the skin following the markings on the skin and passing upwards along a glide plane to exit at a first exit point 34 at the scalp 35 behind the hairline, and namely on the hair bearing scalp .
  • one end of the surgical thread 10 is passed from the entry point 30 through the cannula 32 and up through the first exit point 34.
  • the surgical thread is threaded through the cannula until the clear zone 14 nears or begins to enter the cannula at the incision entry point 30.
  • the threading of the thread stops at this point, so that typically half the length of surgical thread is threaded and half remains hanging from the cannula at the entry point. Accordingly, at this stage the mid point of the thread is usually located around the entry point 30.
  • the cannula is then removed and compression is applied to the bleeding points .
  • Figure 3B illustrates the next step and shows the second pass 26 of the cannula which begins at a second exit point 36 in the scalp behind the hair line a short distance rom the first exit point 34.
  • the second exit point is about 0.5 to 1cm away from the first exit point.
  • the cannula is then inserted down from the second exit point 36 through subcutaneous muscle and soft tissue to emerge through the initial stab incision at entry point 30.
  • the path of this second path of the cannula is substantially parallel to the first path. With the cannula forming a clear path through the facial tissue the other unthreaded end of the surgical thread 10 is threaded from entry point 30 up through the cannula to exit out of the second exit point 36.
  • This step is illustrated by Figure 3C.
  • the cannula is then removed and compression is applied to the bleeding points .
  • the surgical thread thus extends from the scalp 35 down through to the initial entry point 30 where the tissue is to be lifted, looped (or folded) back on itself to extend back up through the soft tissue and muscle below the skin to exit back at the scalp 35.
  • Loop 38 of the surgical thread 10 in Figure 3C is at this point still located above the surface of the face. If threaded correctly, the loop 38 is formed by the clear zone 14 of the surgical thread 10. Additionally, the embedded sections of thread should include the barbed zones 16 in which the barbs are pointed downward toward the clear zone and hence towards the point of lift. Tension is then applied to the thread by pulling up ends 22 at the exit points 34,36 in the directions illustrated by the arrows in Figure 3C.
  • Thread ends 22 are carefully adjusted to ensure that clear zone 14 is positioned substantially central of loop 38.
  • the barbs on the embedded thread prevent the surgical threads slipping down or being pulled down under the natural gravitational tension in the tissue .
  • loop 38 has been drawn into the space created subcutaneously under entry point 30 , further tension is applied on thread ends 22 until the desired level of mid face lift is achieved.
  • a needle (not shown) is then passed subcutaneously through the first and second exit points 34,36 on scalp 35 and one end of the surgical thread 10 is passed through the needle such that both ends now exit from the same exit point.
  • the tension on the thread is then readjusted and then secured at a final position with about three to four knots .
  • the thread is then cut flush to the knot and urged under the skin.
  • the tissue openings at the entry point 30 is then closed over by regular means such as stitching or compression.
  • the mid face lift procedure would then be repeated on the opposite side of the face at a suspension point symmetrical to the first point lifted.
  • FIG. 4 illustrates a second embodiment of the surgical thread 10 which comprises the surgical thread described above but having solid tapered needles 55 attached to both ends of the thread 10.
  • the tapered needles replace the need for using a cannula to pass the surgical thread 10 subcutaneously through the soft tissue and/or muscle. Instead, the needle is introduced into entry point 30 and threaded subcutaneously to the first exit point 34. Replacing the use of a hollow cannula with needles allows the thread to be inserted quickly and more directly through the soft tissue/muscle.
  • the needles illustrated in Figures 4 and 5 are straight and long tapered solid needles .
  • the needles may be shorter.
  • Some lift applications may require a curved needle in which case the needles at the end of the thread may be long or short curved needles .
  • the needles themselves may be made of steel or any other suitable material.
  • the ends of the surgical thread are attached to the long needles at manufacture.
  • the needles may have eyes through which the thread ends may be threaded.
  • Other face lift procedures are performed in a similar manner using either the method of a cannula or using thread attached with needles.
  • another kind of mid face malar mound suspension may require lift of two points on each malar mound. These points are illustrated in Figure 6 as first point 40 which is just below mid point of the malar mound and a second point 42 at the bottom of the malar mound, where a natural dimple occurs. In this procedure all four threads exiting two pairs of first and second exit points 34, 36 would need to be adjusted simultaneously to acquire the desired mid face lift.
  • FIG. 6 An example of an intra hair line lift is illustrated in Figure 6 with the lift occurring at point 44 on the hair line 46.
  • a shorter length of surgical thread 10 would be required for this procedure. In practice, the normal thread length would be used and cut back to the appropriate length .
  • Figure 6 also illustrates an eye lift 48, a brow lift 50 and a neck lift where the incisions for suspension are made at the platysmal bands 52 and 53. In this case the incision would be specifically made in the midline just medial to each band at the level of the mentocervical angle .
  • a technique for performing a jowl suspension is not illustrated but such a procedure would commence with making two stab incisions at the level of the angle of mandible through the bulk of the jowl mound and a third stab may be required at the level of the marionette line.
  • any tissue suspensions not involving the face such as breast and buttocks, would involve the careful assessment of optimal thread entry and exit points followed by insertion of the cannula and threading the surgical thread in a sling as described above.
  • the central clear zone 14 may be modified to increase the "purchase" on the soft tissue, that is, the hold of the loop 38 on the soft tissue.
  • Surgical threads have a tendency to sometimes cut through tissue when applied with force in a transverse direction of the thread.
  • Figures 7A and 7B illustrate two modifications to the clear zone 14 that would prevent this cutting effect and increase the thread' s hold on the tissue .
  • the clear zone 14 in Figure 7A is flattened giving it a ribbon-like appearance wherein the flattened portion can more securely hold the tissue bridge at the entry point in a tissue lift.
  • Figure 7B illustrates a sheath or sleeve 57 surrounding clear zone 14.
  • the sleeve may be provided with a roughened, corrugated or "furry" surface that increases the effective thickness of the clear zone 14 and causes the sleeve 57 to grab hold and adhere to the tissue more securely.
  • the sleeve 57 may be made of a silastic or a dissolvable biodegradable material such as polylactic acid or polydiaxonone, or other suitable material .
  • the clear zone 14 may be braided with more than one thread to increase the effective thickness of the clear zone and reduce the sharp cutting effect through tissue that occurs with a single thread.
  • the present surgical thread and method can be used for lifting more than just full, soft tissue but will also pull skin taut along the length of the thread to give the appearance of evenly smooth and taut skin .
  • the overall result is a non-invasive procedure and a non-obvious , smooth face lift that will reliably last for years .

Abstract

La présente invention a trait à un fil chirurgical (10) pour des interventions de chirurgie plastique comportant une section transparente (14) et une pluralité de saillies acérées (12) de part et d'autre de la section transparente. La section transparente est exempte de saillies alors que les saillies de chaque côté de la section transparente sont inclinées vers la section transparente. L'invention a également trait à un procédé pour la réalisation d'interventions de chirurgie plastique mettant en oeuvre ce fil chirurgical comprenant l'enfilage sous-cutané du fil à travers le tissu et/ou muscle de sorte que le fil se replie sur lui-même en une boucle ou en élingue. La tension du fil est ensuite ajustée depuis les deux extrémités du fil (22) qui s'étendent vers l'extérieur en direction de deux points de séparation distinctes (34, 36) pour assurer une élévation souhaitée. Les saillies résistent à la traction de fil dans la direction du point d'entrée (30) et la section transparente se retrouve au niveau du pli.
PCT/SG2005/000104 2004-04-07 2005-03-31 Fil chirurgical WO2005096956A1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
DE602005023590T DE602005023590D1 (de) 2004-04-07 2005-03-31 Chirurgischer faden
JP2007507282A JP4890440B2 (ja) 2004-04-07 2005-03-31 手術糸
BRPI0508782-1A BRPI0508782B1 (pt) 2004-04-07 2005-03-31 Linha cirúrgica
AT05722351T ATE481036T1 (de) 2004-04-07 2005-03-31 Chirurgischer faden
EP05722351A EP1734870B1 (fr) 2004-04-07 2005-03-31 Fil chirurgical
MXPA06011576A MXPA06011576A (es) 2004-04-07 2005-03-31 Hilo quirurgico.
AU2005230815A AU2005230815B2 (en) 2004-04-07 2005-03-31 Surgical thread
TW094110926A TWI375574B (en) 2004-04-07 2005-04-06 Surgical thread
MYPI20051548A MY144385A (en) 2004-04-07 2005-04-06 Surgical thread
US11/123,214 US8236027B2 (en) 2004-04-07 2005-05-06 Surgical thread
HK07104201.0A HK1096567A1 (en) 2004-04-07 2007-04-21 Surgical thread
AU2010212524A AU2010212524B2 (en) 2004-04-07 2010-08-24 Surgical thread

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SGPCT/SG2004/000090 2004-04-07
US10/850,480 US7601164B2 (en) 2004-04-07 2004-05-21 Surgical thread

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/123,214 Continuation US8236027B2 (en) 2004-04-07 2005-05-06 Surgical thread

Publications (1)

Publication Number Publication Date
WO2005096956A1 true WO2005096956A1 (fr) 2005-10-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SG2005/000104 WO2005096956A1 (fr) 2004-04-07 2005-03-31 Fil chirurgical

Country Status (1)

Country Link
WO (1) WO2005096956A1 (fr)

Cited By (34)

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WO2008014491A1 (fr) * 2006-07-28 2008-01-31 Angiotech Pharmaceuticals, Inc. Dispositif cosmétique de rehaussement du sein et du mamelon et procédé
JP2008200195A (ja) * 2007-02-19 2008-09-04 Daitaro Fukuoka 形成施術用糸およびこれを用いた形成施術方法
WO2008136549A1 (fr) * 2007-05-08 2008-11-13 Hyunjin Yang Outils pour un procédé de suture adhérente anti-compressive renforcée par des fibres
WO2009112683A2 (fr) * 2008-01-21 2009-09-17 1St Surgiconcept Fil chirurgical pour la reconstruction dans le domaine de la chirurgie et de la médecine esthétique
DE102008057216A1 (de) * 2008-11-06 2010-05-12 Aesculap Ag Chirurgischer Faden mit Kern-Mantel-Aufbau
WO2013065923A1 (fr) 2011-10-31 2013-05-10 Kim Jong Woo Greffon pour rhytidectomie tissulaire
US8721681B2 (en) 2002-09-30 2014-05-13 Ethicon, Inc. Barbed suture in combination with surgical needle
US8734485B2 (en) 2002-09-30 2014-05-27 Ethicon, Inc. Sutures with barbs that overlap and cover projections
US8771313B2 (en) 2007-12-19 2014-07-08 Ethicon, Inc. Self-retaining sutures with heat-contact mediated retainers
JP2014131744A (ja) * 2007-07-26 2014-07-17 Alpha Scientific Corp 外科用縫合糸装置、方法、およびそれと共に用いるツール
US8875607B2 (en) 2008-01-30 2014-11-04 Ethicon, Inc. Apparatus and method for forming self-retaining sutures
US8876865B2 (en) 2008-04-15 2014-11-04 Ethicon, Inc. Self-retaining sutures with bi-directional retainers or uni-directional retainers
US8916077B1 (en) 2007-12-19 2014-12-23 Ethicon, Inc. Self-retaining sutures with retainers formed from molten material
US8915943B2 (en) 2007-04-13 2014-12-23 Ethicon, Inc. Self-retaining systems for surgical procedures
US8932328B2 (en) 2008-11-03 2015-01-13 Ethicon, Inc. Length of self-retaining suture and method and device for using the same
US8961560B2 (en) 2008-05-16 2015-02-24 Ethicon, Inc. Bidirectional self-retaining sutures with laser-marked and/or non-laser marked indicia and methods
US9044225B1 (en) 2007-12-20 2015-06-02 Ethicon, Inc. Composite self-retaining sutures and method
JP2015131124A (ja) * 2006-08-07 2015-07-23 シルエット・リフト・ソシエダッド・リミターダ 創傷縫合、組織近置、組織支持、組織懸下、および/または組織固定用の縫合糸
US9125647B2 (en) 2008-02-21 2015-09-08 Ethicon, Inc. Method and apparatus for elevating retainers on self-retaining sutures
US9226748B2 (en) 2007-07-26 2016-01-05 Alpha Scientific Corporation Surgical suturing device, method and tools used therewith
US9248580B2 (en) 2002-09-30 2016-02-02 Ethicon, Inc. Barb configurations for barbed sutures
WO2016135474A1 (fr) * 2015-02-27 2016-09-01 Sinclair Pharmaceuticals Limited Suture pour fixation de tissu mou
US9498893B2 (en) 2007-09-27 2016-11-22 Ethicon, Inc. Self-retaining sutures including tissue retainers having improved strength
US9636110B2 (en) 2013-03-13 2017-05-02 Alpha Scientific Corporation Structural support incorporating multiple strands
US9675341B2 (en) 2010-11-09 2017-06-13 Ethicon Inc. Emergency self-retaining sutures and packaging
US9955962B2 (en) 2010-06-11 2018-05-01 Ethicon, Inc. Suture delivery tools for endoscopic and robot-assisted surgery and methods
WO2018190625A1 (fr) 2017-04-11 2018-10-18 유원석 Suture adhésive à ardillons et son procédé de fabrication
WO2019068928A1 (fr) 2017-10-06 2019-04-11 Thread & Lift Fil chirurgical
US10299786B2 (en) 2013-03-15 2019-05-28 Alpha Scientific Corporation Surgical suturing device with transverse engagement
US10420546B2 (en) 2010-05-04 2019-09-24 Ethicon, Inc. Self-retaining systems having laser-cut retainers
US10492780B2 (en) 2011-03-23 2019-12-03 Ethicon, Inc. Self-retaining variable loop sutures
US10548592B2 (en) 2004-05-14 2020-02-04 Ethicon, Inc. Suture methods and devices
US11007296B2 (en) 2010-11-03 2021-05-18 Ethicon, Inc. Drug-eluting self-retaining sutures and methods relating thereto
CN114177343A (zh) * 2021-11-12 2022-03-15 长春圣博玛生物材料有限公司 一种缝线、制备方法及医用编织物

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Cited By (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9248580B2 (en) 2002-09-30 2016-02-02 Ethicon, Inc. Barb configurations for barbed sutures
US8721681B2 (en) 2002-09-30 2014-05-13 Ethicon, Inc. Barbed suture in combination with surgical needle
US8852232B2 (en) 2002-09-30 2014-10-07 Ethicon, Inc. Self-retaining sutures having effective holding strength and tensile strength
US8795332B2 (en) 2002-09-30 2014-08-05 Ethicon, Inc. Barbed sutures
US8734485B2 (en) 2002-09-30 2014-05-27 Ethicon, Inc. Sutures with barbs that overlap and cover projections
US10779815B2 (en) 2004-05-14 2020-09-22 Ethicon, Inc. Suture methods and devices
US10548592B2 (en) 2004-05-14 2020-02-04 Ethicon, Inc. Suture methods and devices
US11723654B2 (en) 2004-05-14 2023-08-15 Ethicon, Inc. Suture methods and devices
US7871425B2 (en) 2006-07-28 2011-01-18 Angiotech Pharmaceuticals, Inc. Minimally-invasive nipple-lift procedure and apparatus
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