WO2005081649A2 - Composition destinee a reduire la carence en proteines et procede de fabrication de ladite composition - Google Patents

Composition destinee a reduire la carence en proteines et procede de fabrication de ladite composition Download PDF

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Publication number
WO2005081649A2
WO2005081649A2 PCT/RU2005/000109 RU2005000109W WO2005081649A2 WO 2005081649 A2 WO2005081649 A2 WO 2005081649A2 RU 2005000109 W RU2005000109 W RU 2005000109W WO 2005081649 A2 WO2005081649 A2 WO 2005081649A2
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WO
WIPO (PCT)
Prior art keywords
πρi
biomass
mixture
chτο
food
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PCT/RU2005/000109
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English (en)
Russian (ru)
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WO2005081649A3 (fr
Inventor
Robert Meingardtovich Lind
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Robert Meingardtovich Lind
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Application filed by Robert Meingardtovich Lind filed Critical Robert Meingardtovich Lind
Publication of WO2005081649A2 publication Critical patent/WO2005081649A2/fr
Publication of WO2005081649A3 publication Critical patent/WO2005081649A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof

Definitions

  • WHO World Health Organization
  • eating more than half the population of our planet cannot be a good food due to a lack of protein.
  • the food deficiency of the food protein is 1.5 million tons per year. This problem is associated, inter alia, with the disturbances of the habitat of macroorganisms [1].
  • amino acids and carbohydrates Living synthesis of amino acids and carbohydrates "de novo" is not given. Both ⁇ and others receive them from the plants consumed by them.
  • the main source of amino acids for the synthesis of animal protein are amino acids and certain other nitrogen-containing substances (aminosugar, amino acids, nitrogen
  • SIGNIFICANT FOX (DR. 26) 2 bases, some ammonium salts of organic acids and other substances). Hosted foodstuffs for livelihoods that are able to be included in the livestock system are called “raw foodstuffs”. For the division of the quantitative content of "raw food" in the base, the percentage content in it of an element of nitrogen is multiplied by 6.25.
  • SIGNIFICANT FOX (DR. 26) 3 large quantities - around 150 g. To the head. Failure to do so may result in death, and sometimes death. Deficiency of farms in agricultural sector forces scientists and practitioners to search for new, non-standard sources of their implementation.
  • One of them is wood and waste products, which are processed and prepared and processed.
  • the products of the partial hydrolysis of wood can be successfully used to replace parts of bulky traditional foods in ruminant livestock products (see paragraphs. ⁇ ntended ⁇ Communication Communication ⁇ ⁇ station, Canada and ⁇ .
  • the units are equipped with quick installations of continuous operation, in the case of quick processing of large biomass with high pressure (up to 30 réelle Concept).
  • the use and production of vegetable-protein food is also used in Russia for quite a long time [2].
  • SIGNIFICANT FOX (DR. 26) 4 Convert them to the full, corresponding to the requirements of intensive livelihoods, food, and, in addition to the corresponding food, and food.
  • a scheme of the complex processing of wood was developed in order to increase the yield of products assimilated by microorganisms. D ⁇ evesinu ⁇ dve ⁇ gayu ⁇ schel ⁇ chn ⁇ mu gid ⁇ lizu v ⁇ dnym ⁇ as ⁇ v ⁇ m ⁇ a ⁇ ⁇ i 175 ° C ⁇ echenie 2 hours.
  • the cellulose residue is hydrolyzed with sulfuric acid. Then, neutralization of external alkali by acid hydrolysis, separation of lignin, crystallization of sulphate by the addition of sulfuric acid, is eliminated.
  • the solvent is removed, and the substance is diluted to 1% - the concentration of minerals and organic acids is added [household].
  • the technical task of the present invention is the production of a product, which can reduce and / or eliminate the protein deficiency in the commercially available medium.
  • SIGNIFICANT FOX 5 ⁇ e ⁇ niches ⁇ aya task ⁇ eshae ⁇ sya ⁇ em, ch ⁇ ⁇ az ⁇ ab ⁇ an ⁇ e ⁇ a ⁇ a ⁇ to reduce bel ⁇ v ⁇ g ⁇ de ⁇ itsi ⁇ a in ⁇ ganizme, ⁇ eds ⁇ avlyayuschy s ⁇ b ⁇ y ⁇ du ⁇ bi ⁇ l ⁇ giches ⁇ y and ⁇ imiches ⁇ y ⁇ b ⁇ ab ⁇ i bi ⁇ massy or ⁇ d ⁇ v ⁇ i uchas ⁇ ii mi ⁇ ganizm ⁇ v, ⁇ i e ⁇ m is ⁇ dn ⁇ e sy ⁇ e yavlyae ⁇ sya uglev ⁇ ds ⁇ de ⁇ zhaschey bi ⁇ mass ⁇ y ⁇ as ⁇ i ⁇ eln ⁇ g ⁇ ⁇ is ⁇ zhdeniya in ⁇ y u ⁇ lev ⁇ dnaya Part s ⁇ s ⁇ avly
  • the resulting large mass can be used by the body of a small assimilable protein, the so-called. raw squirrel.
  • Another method of the invention is the method of receiving the medicine, which is often the following.
  • SIGNIFICANT FOX 6 ⁇ du ⁇ in ⁇ m uglev ⁇ dnaya Part eg ⁇ s ⁇ s ⁇ avlyae ⁇ not less than 5%, and sy ⁇ e izmelchayu ⁇ smeshivayu ⁇ with v ⁇ d ⁇ y, ⁇ b ⁇ ab ⁇ u vedu ⁇ m ⁇ l ⁇ chn ⁇ islymi ba ⁇ e ⁇ iyami, ⁇ i nachaln ⁇ m i ⁇ s ⁇ de ⁇ zhanii 0.2 - 5.0% on ⁇ azhdy li ⁇ v ⁇ dn ⁇ y mixture in ⁇ ubi ⁇ uyu ⁇ mixture ⁇ i ⁇ em ⁇ e ⁇ a ⁇ u ⁇ e 36- 42 ° C for at least 6 chas ⁇ v, ⁇ dde ⁇ zhivaya ⁇ on u ⁇ vne 6.75 + 0.05 introduction gid ⁇ isi amm ⁇ niya, ⁇ sle s ⁇ abilizatsii u ⁇
  • Acid hydrolysis is produced at a temperature of 1.0 and a temperature of 90 + 0.5 ° ⁇ for 2.0 + . 0.1 hours with use of concentrated sulfuric acid.
  • P ⁇ i ⁇ b ⁇ ab ⁇ e g ⁇ ub ⁇ y is ⁇ dn ⁇ y bi ⁇ massy, m ⁇ zhe ⁇ by ⁇ ⁇ imenen and schel ⁇ chn ⁇ y gid ⁇ liz, na ⁇ ime ⁇ d ⁇ evesinu ⁇ dve ⁇ gayu ⁇ schel ⁇ chn ⁇ mu gid ⁇ lizu v ⁇ dnym ⁇ as ⁇ v ⁇ m ⁇ a ⁇ ⁇ i 175 ° C ⁇ echenie 2 hours.
  • SIGNIFICANT FOX (DR. 26) 8 Then, during the whole process, we added 10% ammonia in small amounts to maintain the medium at a level of 6.75 + 0.05. At the time of the end, the process of dumping to the original volume of sugar product in the mixture was added 265 ml. 10% ammonia solution. Experimental liquid in a quantity of 50 ml. We handed over to the analysis of all of them. Williams. The analysis showed that the content of the joint venture in the sample is equal to 13.2%. Upon thickening of the resulting suspension on a vacuum evaporator, up to 40% of the obtained mass was 29.7% of the joint venture, in the result of dry matter - 74.25% of the joint venture.
  • the glass was placed in a water bath at a temperature of 90 ° ⁇ . After 2 hours of operation, they settled down to 40 ° C. Sulfuric acid was neutralized by 10% ammonia in water, bringing it to 6.75.
  • the total volume of 10% ammonia spent on the neutralization of the resulting acid and small acid was 9 ml.
  • the resulting bulk mixture was dried at a temperature of 50 ° C, brought up to a constant weight, equal
  • the mass obtained at the end of the process was dried at a temperature of 50 ° C, brought up to a constant weight of 25 g, and crushed to a large share. Then, 10 years of the obtained product and 10 years of the original beetroot press were delivered to the laboratory for the appraisal of livelihoods and their livelihood. Williams. The results of the analysis showed that the content of the joint venture increased from 8.4% to 47.1% in the previous product.
  • Example 4 1,0. Placed in a water bath at 90 ° ⁇ . After 2 hours of operation, the food was cooled to 40 ° C. They brought the leaven, as in Example 4, added 0.5 ml of a 10% ammonia solution in the water for bringing it to 6.75 + 0.05. Then, at the time of acidification of the steady state and reduction to 6.5, we added 10% of ammonia in quantity, which is necessary for bringing up to 6.75 + 0.05. For the whole process at a time, when the development of small acid was discontinued, the mixture lost its consistency, 40 ml of 10% was consumed. The resulting mass was dried, brought to a reasonable weight of 28 g, and crushed to a large industrial structure.
  • EXAMPLE 6 (EXPERIMENT WITH STRAW) ⁇
  • SIGNIFICANT FOX (DR. 26) 11 accents.
  • 10% of ammonia was introduced into slightly smaller amounts, supporting the environment at a level of 6.75 + 0.05.
  • the resulting mass at the end of the process was dried at a temperature of 50 ° C, brought to a constant weight, equal to 25 g., Grinded before disintegration.
  • 10 g of the obtained product and 10 g of the original source of winter wheat were delivered to the laboratory of the Russian Research Institute of Food and Agriculture. Williams.
  • the results of the analysis show that the content of the joint venture was up from 3.2% in the original product to 14.3% in the finished product.
  • SIGNIFICANT FOX (DR. 26) 12, it is possible to use it as an additional source of digestible proteins for the purpose of solving the problem of protein deficiency.
  • LIST OF LISTS 1. ⁇ . ⁇ . Zaqarów and d ⁇ . “Health of the environment: pricing practice”, Russia, 2000. 2. “PRODUCTION AND APPLICATION OF PRODUCTS FOR PREPARATIONS OF WOODEN PRODUCTS”, Moscow, “Forest industry”, 1978. 3. ⁇ . ⁇ . Panakova, D.G. Pobedimsky "Therapeutic basis of the technology of biological products", Moscow, "1990,”

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Processing Of Solid Wastes (AREA)

Abstract

L'invention appartient au domaine de la pharmacologie biomoléculaire et permet de fabriquer une composition capable de réduire la carence en protéines de l'organisme d'un mammalien. Elle concerne également un procédé de fabrication correspondant et porte sur une composition qui se présente comme un produit du traitement biologique ou chimique d'une biomasse végétale ou de ses déchets avec la participation de micro-organismes. La matière de base utilisée est une biomasse hydrocarbonée d'origine végétale, la partie hydrocarbonée représentant pas moins de 5 % de la biomasse initiale totale. La biomasse est mélangée avec de l'eau, et l'on y ajoute des bactéries bifidus, prises comme ferment initial, avec une teneur de 0,2 à 0,5 % pour chaque litre de mélange aqueux. Le mélange est incubé à une température de 36 à 42 °C pendant au moins 6 h, le pH étant maintenu à un niveau de 6,75 ? 0,05 grâce à l'apport d'hydroxyde d'ammonium. Le mélange pâteux ainsi obtenu peut être utilisé en tant que précurseur de protéine assimilable. L'invention concerne aussi une caractéristique du procédé de fabrication, qui comprend le traitement de la biomasse initiale par des bactéries de bifidus et l'apport fractionnel d'hydroxyde d'ammonium visant à maintenir un niveau de pH à 6,75 ? 0,05, le produit final se présentant comme une masse comprenant de précurseurs de protéine assimilables. L'invention permet ainsi d'élargir la base de fabrication de protéines destinées aux produits alimentaires ou aux aliments.
PCT/RU2005/000109 2004-02-27 2005-02-25 Composition destinee a reduire la carence en proteines et procede de fabrication de ladite composition WO2005081649A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2004105799 2004-02-27
RU2004105799/15A RU2267325C2 (ru) 2004-02-27 2004-02-27 Препарат для снижения белкового дефицита в организме и способ получения такого препарата

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WO2005081649A2 true WO2005081649A2 (fr) 2005-09-09
WO2005081649A3 WO2005081649A3 (fr) 2005-12-08

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2044491C1 (ru) * 1992-12-30 1995-09-27 Юрий Иванович Юдин Способ приготовления кормосмеси для молодняка сельскохозяйственных животных
US5902797A (en) * 1997-11-10 1999-05-11 Beth Israel Deaconess Medical Center Nutritional supplement for use in the treatment of attention deficit
RU2161895C2 (ru) * 1999-04-08 2001-01-20 Дьяконов Лев Петрович Порошковая смесь
RU2221582C2 (ru) * 2002-02-08 2004-01-20 Гуревич Константин Георгиевич Средство для лечения дисбактериоза и способ его получения

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2044491C1 (ru) * 1992-12-30 1995-09-27 Юрий Иванович Юдин Способ приготовления кормосмеси для молодняка сельскохозяйственных животных
US5902797A (en) * 1997-11-10 1999-05-11 Beth Israel Deaconess Medical Center Nutritional supplement for use in the treatment of attention deficit
RU2161895C2 (ru) * 1999-04-08 2001-01-20 Дьяконов Лев Петрович Порошковая смесь
RU2221582C2 (ru) * 2002-02-08 2004-01-20 Гуревич Константин Георгиевич Средство для лечения дисбактериоза и способ его получения

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Publication number Publication date
RU2267325C2 (ru) 2006-01-10
RU2004105799A (ru) 2005-08-10
WO2005081649A3 (fr) 2005-12-08

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