WO2005046781A1 - Device and method for insertion of a cannula of an infusion device - Google Patents

Device and method for insertion of a cannula of an infusion device Download PDF

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Publication number
WO2005046781A1
WO2005046781A1 PCT/US2004/030344 US2004030344W WO2005046781A1 WO 2005046781 A1 WO2005046781 A1 WO 2005046781A1 US 2004030344 W US2004030344 W US 2004030344W WO 2005046781 A1 WO2005046781 A1 WO 2005046781A1
Authority
WO
WIPO (PCT)
Prior art keywords
needle
housing
hub
skin
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/030344
Other languages
English (en)
French (fr)
Inventor
Mark Henry Faust
James Marrs
Steve Cote
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smiths Medical ASD Inc
Original Assignee
Smiths Medical MD Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smiths Medical MD Inc filed Critical Smiths Medical MD Inc
Priority to AU2004289185A priority Critical patent/AU2004289185B2/en
Priority to EP04784263.8A priority patent/EP1691877B1/en
Priority to CA2544303A priority patent/CA2544303C/en
Priority to JP2006539475A priority patent/JP4685024B2/ja
Publication of WO2005046781A1 publication Critical patent/WO2005046781A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1581—Right-angle needle-type devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1583—Needle extractors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1585—Needle inserters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion

Definitions

  • the present invention relates to a device for assisting in the introduction of a cannula of an infusion device into the skin of a patient for delivery of a substance to the patient.
  • Infusion devices are used to deliver substances such as medications into the subcutaneous layer of skin of a patient.
  • Devices for assisting in insertion of the cannula of an infusion device into the skin of the patient are known.
  • some devices utilize springs to automatically drive a needle into the skin of a patient to introduce the cannula of the infusion device into the subcutaneous layer.
  • a needle is used to introduce the cannula of the infusion device into the subcutaneous layer of skih, there is a risk associated with inadvertent exposure to the needle.
  • patients may react adversely to viewing the needle prior to insertion and may, for example, be reluctant to place the needle into the skin.
  • Prior devices may not adequately shroud this needle prior to and/or after introduction of the infusion device.
  • a device includes a needle used to insert the cannula of an infusion device into the skin of a patient. Once the cannula of the infusion device is inserted into the skin, the device moves the needle to a retracted state within the device.
  • a device is configured to move a needle and associated cannula of an infusion device from a delivery state to a trigger state at which the cannula of the infusion device is inserted into the skin of a patient.
  • a device includes a needle that can be used to insert a cannula of a site into the skin of a patient. Upon insertion of the cannula, the needle can be removed from the skin.
  • a cap is provided that can be placed onto the device prior to and after use of the device to provide a sterile environment and/or to reduce exposure to the needle.
  • Figure 1 is a side view of an example embodiment of a device used to introduce a cannula of an infusion device into a patient made in accordance with the present invention.
  • Figure 2 is an exploded side view of the device of Figure 1.
  • Figure 3 is a perspective view of a housing of the device of Figure 1.
  • Figure 4 is a side view of the housing of Figure 3.
  • Figure 5 is an end view of the housing of Figure 3.
  • Figure 6 is a perspective view of a cylinder hub of the device of Figure 1.
  • Figure 7 is side view of the cylinder hub of Figure 6.
  • Figure 8 is another side view of the cylinder hub of Figure 6.
  • Figure 9 is an end view of the cylinder hub of Figure 6.
  • Figure 10 is a perspective view of a needle hub of the device of Figure 1.
  • Figure 11 is a side view of the needle hub of Figure 10.
  • Figure 12 is another side view of the needle hub of Figure 10.
  • Figure 13 is an end view of the needle hub of Figure 10.
  • Figure 14 is a perspective view of a sleeve of the device of Figure 1.
  • Figure 15 is a side view of the sleeve of Figure 14.
  • Figure 16 is another side view of the sleeve of Figure 14.
  • Figure 17 is an end view of the sleeve of Figure 14.
  • Figure 18 is a top view of an adhesive portion of the device of Figure 1.
  • Figure 19 is a cross-sectional view taken along line 19-19 of the adhesive portion of Figure 18.
  • Figure 20 is an exploded view of the adhesive portion of Figure 18.
  • Figure 21 is a perspective view of a cap of the device of Figure 1.
  • Figure 22 is a side view of the cap of Figure 21.
  • Figure 23 is an end view of the cap of Figure 21.
  • Figure 24 is a side view of the device of Figure 1 with the cap removed.
  • Figure 25 is a side view of the device of Figure 24 in a trigger state.
  • Figure 26 A is a cross-sectional view taken along line 26A-26A of the device of Figure 1 in a ship state.
  • Figure 26B is a cross-sectional view taken along line 26B-26B of the device of Figure 1 in the ship state.
  • Figure 27A is a cross-sectional view taken along line 27A-27A of the device of Figure 24 in a delivery state.
  • Figure 27B is a cross-sectional view taken along line 27B-27B of the device of Figure 24 in the delivery state.
  • Figure 28 A is a cross-sectional view taken along line 28A-28A of the device of Figure 25 in a trigger state.
  • Figure 28B is a cross-sectional view taken along line 28B-28B of the device of Figure 25 in the trigger state.
  • Figure 28C is a cross-sectional view of the device of Figure 28B illustrating the adhesive portion being sheared from a surface of the sleeve.
  • Figure 29 A is a cross-sectional view of the device of Figure 28 A with the needle hub retracted.
  • Figure 29B is a cross-sectional view of the device of Figure 28B with the needle hub retracted.
  • Figure 30A is a cross-sectional view taken along line 30A-30A of the device of Figure 24 in a retracted state.
  • Figure 30B is a cross-sectional view taken along line 30B-30B of the device of Figure 24 in the retracted state.
  • Figure 31 is a cross-sectional view of a portion of another example embodiment of a device used to introduce an infusion device into a patient made in accordance with the present invention.
  • Figure 32A is a cross-sectional view of another example embodiment of a device used to introduce an infusion device into a patient in a ship state made in accordance with the present invention.
  • Figure 32B is a cross-sectional view along a perpendicular plane of the device of Figure 32 A.
  • Figure 33 A is a cross-sectional view of the device of Figure 32A in a delivery state.
  • Figure 33B is a cross-sectional view of the device of Figure 32B in the delivery state.
  • Figure 34A is a cross-sectional view of the device of Figure 32A in a retracted state.
  • Figure 34B is a cross-sectional view of the device of Figure 32B in the retracted state.
  • Figure 35 is a perspective view of a sleeve of the device of Figure 32A.
  • Figure 36 is a side view of the sleeve of Figure 35.
  • Figure 37 is another side view of the sleeve of Figure 35.
  • Figure 38 is an end view of the sleeve of Figure 35.
  • Figure 39 is a perspective view of another example embodiment of a device used to introduce an infusion device into a patient made in accordance with the present invention.
  • Figure 40 is another perspective view of the device of Figure 39.
  • Figure 41 is a side view of the device of Figure 39.
  • Figure 42 is an end view of the device of Figure 39.
  • Figure 43 is an opposite end view of the device of Figure 39.
  • Figure 44 is a perspective view of another example embodiment of a device used to introduce an infusion device into a patient made in accordance with the present invention.
  • Figure 45 is a side view of the device of Figure 44.
  • Figure 46 is another side view of the device of Figure 44.
  • Figure 47 is an end view of the device of Figure 44.
  • Figure 48 is another end view of the device of Figure 44.
  • Figure 49 is a cross-sectional view taken along line 49-49 of the 10 device of Figure 45.
  • Figure 50 is a side view of another example embodiment of a device used to introduce a cannula of an infusion device into a patient including a tamper- evident seal made in accordance with the present invention.
  • Figure 51 is a side view of the device of Figure 50 with the cap 15 uncoupled and the tamper-evident seal having been broken.
  • Figure 52 is a cross-section
  • Embodiments of the present invention relate to devices for assisting 20 in the introduction of an infusion device, specifically a cannula of the infusion device, into the subcutaneous layer of skin of a patient.
  • a device 100 is shown.
  • the device 100 is used to introduce a cannula of an infusion device, such as a set, site, or other access device, into the skin of the patient.
  • the set, site, or 25 other access device can then be used to deliver drugs or other fluid to the patient, such as from an infusion pump.
  • the device 100 generally includes a housing 110, a cylinder hub 120, a needle hub 130, a sleeve 140, a spring 150, an adhesive portion 160, and a cap 170.
  • the housing 110 is shown.
  • the housing 110 is preferably cylindrical in shape and includes a closed upper end 111 and an open lower end 112.
  • the housing 110 further preferably includes a portion 118 with a knurled surface to enhance a patient's grip on the housing 110, as well as a threaded portion 113 positioned adjacent the open lower end 112.
  • the cylinder hub 120 is shown in greater detail.
  • the cylinder hub 120 includes first and second ends 221 and 222 and an interior passage 223.
  • two opposing slots 225 are formed on opposite sides of the cylinder hub 120 and generally extend from a mid-portion 224 of the hub 120 to the first end 221.
  • the cylinder hub 120 includes opposing apertures 226 formed in the cylinder hub 120 adjacent the second end 222.
  • the first end 221 of the cylinder hub 120 is coupled to the upper end 111 of the housing 110 by tabs 119 on the housing 110 engaging shoulders 228 formed by the cylinder hub 120. See, for example, Figures 6-8, 26A, and 26B.
  • members 121 of the housing 110 are received in slots 229 of the cylinder hub 120.
  • the housing 110 and cylinder hub 120 can be formed as a single unit.
  • the needle hub 130 includes a main body 331 with first and second ends 332 and 333, and a needle 336 (hollow or solid) coupled to the main body 331.
  • the main body 331 includes opposing wings 334 formed at the first end 332 and opposing barbs 335 at the second end 333.
  • the needle hub 130 is positioned in the interior passage 223 of the cylinder hub 120 such that the opposing wings 334 of the needle hub 130 extend through the opposing slots 225 of the cylinder hub 120. See Figures 6, 8, 26B, 27B, 28B, 29B, and 30B.
  • the opposing barbs 335 of the needle hub 130 extend through the opposing apertures 226 of the cylinder hub 120 and engage shoulders 227 formed by the apertures 226 so that the needle hub 130 is held in a fixed position relative to the cylinder hub 120 and the housing 110. See, for example, Figures 6, 8, 26A, 27 A, and 28A. Referring now to Figures 14-17, the sleeve 140 is shown. The sleeve
  • the sleeve 140 is preferably cylindrical in shape and includes first and second ends 441 and 442 and interior passage 443. Opposing projections 444 extend into the passage 443 adjacent to a shoulder 445. On the exterior of the sleeve 140 channels 446 are formed, as well as railways 447 with barbs 448 formed on ends thereof.
  • the sleeve 140 is coupled to the housing 110 such that the housing 110 can be moved longitudinally with respect to the sleeve 140. Specifically, the railways 114 of the housing are received in the channels 446 of the sleeve 140.
  • the railways 447 of the sleeve 140 are received in the channels 115 of the housing 110.
  • Barbs 448 on the railways 447 of the sleeve 140 engage projections 116 in the channels 115 of the housing 110 so that the housing 110 remains slideably coupled to the sleeve 140 in opposition to the force exerted by the spring 150 (described further below) .
  • the spring 150 includes first and second ends 152 and 154. See, for example, Figure 26B.
  • the spring 150 surrounds a portion of the cylinder hub 120 and extends within the passage 443 of the sleeve 140.
  • the first end 152 of the spring 150 is seated on the shoulder 445 of the sleeve 140, and the second end 154 of the spring 150 engages the opposing wings 334 of the needle hub 130 extending through the opposing slots 225 of the cylinder hub 120.
  • the spring 150 is in a compressed state as shown in Figures 26 A, 26B, 27 A, 27B, 28A, and 28B and therefore applies force against the wings 334 of the needle hub 130, biasing the needle hub 130 in an upward direction.
  • barbs 335 of the main body 331 of the needle hub 130 are engaged against shoulders 227 of the apertures 226 of the cylinder hub 120 to retain the needle hub 130 in place with respect to the cylinder hub 120. See, for example, Figure 26A.
  • an adhesive portion 160 is positioned on a surface 449 at the second end 442 of the sleeve 140 (see Figures 14 and 17).
  • the surface 449 preferably acts as a framework that stabilizes the adhesive portion 160 prior to placement on the patient.
  • the adhesive portion 160 includes layers 662, 663, and 664, as well as liners 661 and 665.
  • Liners 661 and 665 also preferably include tabs 666 and 667 that allow for removal of the liners 661 and 665 as described below.
  • the adhesive portion 160 can be coupled to the surface 449 of sleeve 140 in a variety of manners.
  • the liner 661 is removed, and layer 662 is coupled to the surface 449 using an adhesive.
  • a top surface 669 of layer 664 and/or a lower end of the infusion device includes an adhesive to couple the infusion device to the adhesive portion 160 as the infusion device is moved into contact with the adhesive portion. See Figures 28A, 28B, and 28C.
  • the liner 665 is preferably removed, and a lower surface 668 of the layer 664 includes an adhesive to couple the adhesive portion 160 to the skin of the patient.
  • the site is loaded into the device 100 prior to application of the adhesive portion 160 onto the device 100, and preferably both liners 661 and 665 are removed as described above prior to attachment of the adhesive portion to the sleeve 140 and coupling of the cap 170 to the housing 110. i this manner, the patient preferably does not need to remove any liners prior to application of the adhesive portion 160 to the skin and introduction of the site into the skin.
  • the layer 664 does not include any holes, but instead is pierced by the needle 336 as the needle 336 is advanced towards the skin, as described further below.
  • the adhesive portion 160 includes adhesive on one or more of surfaces 668 and 669 to allow the adhesive portion 160 to be coupled to the sleeve 140, site, and/or to the skin of the patient.
  • Typical adhesives that can be used on the adhesive portion 160 include, without limitation, acrylic adhesive, synthetic rubber-based adhesive, acrylate adhesive, and silicone- based adhesive.
  • the adhesive portion 160 includes films with adhesives thereon, such as a TegadermTM film manufactured by 3MTM or an IV3000TM film manufactured by Smith & Nephew.
  • the tape layer 662 is 3MTM 9731 tape
  • layers 663 and 664 are 3MTM TegadermTM p/n 9842.
  • the cap 170 is illustrated.
  • the cap 170 includes a closed first end 772 and an open second end 774.
  • the cap 170 preferably includes an exterior with a knurled surface 778 to enhance the patient's grip on the cap 170.
  • the interior of the cap 170 includes a threaded portion 776 positioned adjacent the open second end 774 so that the threaded portion 776 can be threaded onto the threaded portion 113 of the housing 110 to seal the device 100. See Figures 1, 26A, and 26B.
  • a gasket 122 is provided on the threaded portion 113 of the housing 110 to create a seal between the cap 170 and the housing 110 as the cap 170 is threaded onto the housing 110. See Figures 26A and 26B. hi this manner, the internal components of the device 100 (e.g., needle 336 and site 800) can be maintained in a substantially sterile state prior to removal of the cap 170. Further, the cap 170 can function to maintain the device 100 in a ship state (i.e., the housing 110 can not be moved relative to the sleeve 140) prior to removal of the cap 170 from the housing 110.
  • a ship state i.e., the housing 110 can not be moved relative to the sleeve 140
  • the cap 170 and/or housing 110 can be formed to provide a tamper-evident seal so that the patient can determine when the cap 170 has been previously uncoupled from the housing 110.
  • a tamper-evident band 178 is shown in an alternative embodiment of the device 100' shown in Figures 50-52.
  • the band 178 includes tabs 179 that are coupled to the cap 170 as shown in Figure 50.
  • the tabs 179 break away from the cap 170, and the seal 178 remains coupled to the housing 110, as shown in Figure 51.
  • the cap 170 and band 178 can be placed on the device 100' during manufacturing as a single unit. For example, as shown in Figure 52, trie cap 170 and band 178 can be pushed onto the device 100' (note that threads 512 and 514 can be rounded to allow the cap 170 to be pressed onto the device 100') so that portion 520 of the band 178 passes over and engages shoulder 522 of the housing 110 to retain the band 178 on the housing 110 when the cap 170 is unthreaded and tabs 179 are broken.
  • notches 524 formed periodically along the band 178 prevent the cap 170 from bottoming out against the band 178 as the cap 170 and band 178 are pushed onto the device 100' so that the tabs 179 remain intact.
  • a portion 502 extending along an interior circumference of the cap 170 can also be formed to engage the outer surface of the housing 110 to create a seal between the housing 110 and the cap 170. It can be desirable to provide a tamper-evident seal, for example, so that the patient can assure that the device 100' is has not been previously opened and is sterile prior to use. Other methods of indicating tampering can also be used.
  • the device 100 can be used to introduce a cannula of an infusion device into the subcutaneous layer of skin of the patient
  • the infusion device includes a site 800, the site 800 including a cannula for delivery of a substance into the subcutaneous layer of skin of the patient.
  • Site 800 is linked by tubing (not shown) with a fluid source, such as an infusion pump (not shown) to deliver fluid to the patient through the cannula.
  • a fluid source such as an infusion pump (not shown) to deliver fluid to the patient through the cannula.
  • the site 800 can be made in accordance with that disclosed in U.S. Patent Application Serial No. .10/705,736, the entirety of which is hereby incorporated by reference. However, sites of other configurations can also be used.
  • the device 100 is illustrated in various states of use. As shown in Figures 1, 26 A, and 26B, the device 100 is in a ship state prior to use. As shown in Figures 24, 27 A, and 27B, the device 100 is in a delivery state ready to deliver the cannula of an infusion device into the skin of the patient. As shown in Figures 25, 28A, 28B, and 28C the device 100 is in a trigger state, or the state at which the needle 336 and the cannula of the site 800 have been fully inserted into the subcutaneous layer of skin of the patient, and the needle hub 130 and associated needle 336 are about to be retracted.
  • a trigger state or the state at which the needle 336 and the cannula of the site 800 have been fully inserted into the subcutaneous layer of skin of the patient, and the needle hub 130 and associated needle 336 are about to be retracted.
  • the device 100 is in a retracted state with the needle hub 130 and associated needle 336 having been retracted into the device 100.
  • the device 100 is in a fully retracted state with the housing 110 and sleeve 140 returned to an uncompressed position relative to one another.
  • An example method of use of the device 100 is as follows.
  • the device 100 is provided to a patient with the cap 170 coupled to the housing 110, as shown in Figures 1, 26A, and 26B.
  • the site 800 has been previously loaded (i.e., preloaded) into the device 100 during, for example, the manufacturing process for the device 100.
  • the cap 170 is then unthreaded from the housing 110, and the sleeve 140 of the device 100 is positioned so that the adhesive portion 160 (i.e., surface 668) contacts the skin 900 of the patient. See Figures 24, 27A, and 27B.
  • the patient applies pressure to the upper end 111 of the housing 110 to move the housing 110 and associated structures including the cylinder hub 120 and needle hub 130 (including needle 336 and site 800) in a direction A with respect to the sleeve 140 and toward the skin 900 of the patient.
  • the needle 336 of the needle hub 130 and associated site 800 are moved in the direction A, the needle 336 and the cannula 806 of the site 800 are introduced into the skin 900 of the patient, hi addition, as the needle hub 130 is moved toward the sleeve 140, the spring 150 is further compressed.
  • the device 100 is in a trigger state, as illustrated in Figures 25, 28A, 28B, and 28C. In this state, the barbs 335 that couple the needle hub 130 to the cylinder hub 120 are biased inwardly through contact with the projections 444 formed by the sleeve 140.
  • the needle hub 130 is positioned so that a lower portion of the site 800 travels slightly beyond the second end 442 of the sleeve 140 as shown in Figure 28C.
  • This "over-travel" assures that the adhesive portion 160 is properly sheared away from the surface 449 of the sleeve 140 and allows for the coupling of the site 800 to the adhesive portion 160.
  • the lower portion of the site 800 travels beyond the second end 442 of the sleeve 140 by between 50 to 100 thousandths of an inch, more preferably approximately 70 thousandths of an inch.
  • the spring 150 which has been compressed through the movement of the housing 110 in the direction A., propels the needle hub 130 and associated needle 336 in the direction B up through the cylinder hub 120 into the upper end 111 of the housing 110, while leaving the site 800 and associated cannula 806 positioned in the skin 900 of the patient, as shown in Figures 29 A and 29B.
  • the spring 150 causes the housing 110 and cylinder hub 120 to move in the direction B as shown in Figures 30A and 30B to a fully retracted state.
  • the sleeve 140 is removed from contact with the skin 90O, and the cap 170 can be replaced onto the threaded portion 113 of the housing 110 of the device 100.
  • FIG. 31 a portion of an alternative device is shown including cylinder hub 120' and needle hub 130'.
  • the cylinder hub 120' and needle hub 130' are similar to cylinder hub 120 and needle hub 130 described above, except that the cylinder hub 120' includes projections 129 formed near the first end 221 of the cylinder hub 120', and the needle hub 130' includes barbs 139 formed on the first end 332.
  • the barbs 139 are configured to ride inside the interior passage 223 of the cylinder hub 120' during retraction of the needle 336 in the direction B until the barbs 139 extend beyond the projections 129 of the cylinder hub 120'.
  • a device 100" is illustrated in Figures 32-38.
  • Device 100" is similar to device 100 described above, except that the sleeve (e.g., sleeve 140) is replaced with a trigger 140'.
  • the trigger 140' does not function as sleeve 140 to shroud the needle 336 prior to insertion, but instead trigger 140' functions to cause retraction of the needle 336 upon full insertion, as described further below.
  • trigger 140' functions to cause retraction of the needle 336 upon full insertion, as described further below.
  • needle 336 is exposed as shown in Figures 33A and 33B.
  • the patient simply inserts the needle 336 and associated cannula 806 of the site into the skin by grasping the housing 110 and introducing the exposed needle 336 into the skin.
  • the trigger 140' contacts the skin and thereby causes the needle hub 130 including the needle 336 to be retracted into the housing 110, leaving the site 800 in place on the skin.
  • the trigger 140' is automatic, in that the trigger 140' is configured to cause barbs 335 of the needle hub 130 to be displace inwardly to release the needle hub 130 from the cylinder hub 120, and the spring 150 can thereupon move the needle hub 130 and associated needle 336 in the direction B into an upper portion of the housing 110 as shown in Figures 34A and 34B.
  • the trigger 140' can be configured to be manually actuated by the patient to cause retraction of the needle hub 130 and associated needle 336 once the cannula 806 has been fully inserted.
  • FIGs 39-43 another embodiment of a device 100'" is shown.
  • the device 100'" is a manual device in that the device 100"' includes only a housing 110', needle 336, and cap (not shown) that can be threaded onto the housing 110'.
  • a site (not shown) can be preloaded onto the needle 336 and the cap placed on the housing 110' to create a sterile environment prior to use.
  • the patient preferably removes the cap from the housing 110' and, holding the housing 110' inserts the needle and associated cannula of the site into the skin. Once the cannula is completely inserted, the patient moves the housing 110' in the opposite direction to remove the needle from the skin while leaving the site in place. Finally, the patient preferably reapplies the cap to the housing 110' to reduce the chance for further inadvertent exposure to the needle 336. The device 100'" can then be discarded or reused as desired. Referring now to Figures 44-49, another example embodiment of a device 950 for assisting in the introduction of a site 970 is shown. The device 950 differs from the device 100.
  • the device 950 is automated in that a spring 960 is used to drive the needle and cannula of the site into the skin of the patient.
  • the device 950 includes a housing 958, cap 952, lock member 962, needle hub 965, main body 980, retainer body 978, and sleeve 982. Also included are the first spring 960 and a second spring 966.
  • the device 950 functions as follows.
  • the lock member 962, needle hub 964, and retainer body 978 are moveable longitudinally with respect to the housing 958 and sleeve 982 of the device 950.
  • the lock member 962 is positioned so that needle 968 of the needle hub 965 is accessible from open end 984 of the device 950.
  • the site 970 can then be loaded onto the needle 968 by threading the cannula of the site 970 onto the needle 968. Openings 986 are formed by the housing 958 to accommodate sites 970 of various sizes (e.g., wings formed on sites).
  • the lock member 962 is moved in a direction C by the patient using projections 974 that are accessible through slot 976 of housing 958 until barbs 956 of the lock member 962 engage an outer surface of the housing 958, as shown in Figure 49. In this position, the device 950 is ready to insert the site 970 into the skin of the patient.
  • the sleeve 982 of the device 950 is placed against the skin of the patient.
  • the cap 952 is pressed by the patient. Once pressed, shoulders 954 on an opposite end of the cap 952 engage and push the barbs 956 of the lock member 962 toward one another to disengage the barbs 956 from the housing 958.
  • the lock member 962, main body 980, needle hub 965, retainer body 978, and associated site 970 are moved by the first spring 960 a the direction D.
  • the device 950 continues to move the site 970 towards the skin, thereby introducing the needle 968 and cannula of the site 970 into the skin.
  • barbs 964 of the needle hub 965 engage ramped surfaces 972 of the sleeve 982, causing the barbs 964 to be forced toward one another.
  • the barbs 964 have been forced inwardly by the surfaces 972 sufficiently to clear ends 988 of the main body 980, and the second spring 966 moves the needle hub 965 in the direction C into a passage 990 formed by the main body 980.
  • the needle 968 is removed from the site 970, leaving the site 970 in place on the skin.
  • each device can provide ease in placement of the site on the skin, preferably allowing the user to place the site with the device where desired on the body using a single hand to operate the device.
  • several embodiments disclosed herein include structures that cover or hide the needle prior to insertion of the site, and also cause the needle to be retracted into the device after insertion to protect against inadvertent contact with the needle.
  • several embodiments of the devices disclosed herein can automatically retract the needle while leaving the site placed on the skin, thereby reducing the patient's contact with the exposed needle.
  • this retraction is automatic in that once the device reaches the trigger state there is no further action required by the patient to cause the needle to be retracted.
  • the automatic retraction of the needle also limits the dwell time of the needle in the patient, increasing comfort for the patient.
  • the action of inserting the needle into position on the skin using the devices disclosed herein can function to hold the site on the surface of the skin during needle retraction. This can assist in adherence of the adhesive portion to the skin and reduce the chances of separation between the adhesive portion and site and the skin during needle retraction.
  • the housing and cap of several of embodiments of the devices disclosed herein allow the various components of the devices including the needle and infusion device to be delivered to the patient in a self-contained, sterile environment prior to use.
  • the configuration further minimizes the need for packaging surrounding the devices, reducing manufacturing cost and increasing ease in use of the devices.
  • the configuration also allows the housing and cap to protect and maintain the infusion device on the needle of the device.
  • the configuration and disposable nature of the devices further allow ease in discarding of the devices after use.
  • the configuration of several embodiments of the devices disclosed herein can allow the site to be preloaded into the device, thereby providing ease of use for the patient and reducing the patient's exposure to the needle.
  • single-use embodiments disclosed herein preferably do not require that the patient load the site into the device prior to insertion, but instead provide the device with the site preloaded.
  • Some embodiments of the devices allow for both automatic delivery of the site and withdrawal of the needle, thereby automating the entire introduction process for the patient. While single use devices are preferred, reusable devices wherein the needle retracts but can be reloaded are also anticipated.
  • the above specification, examples and data provide a complete description of the manufacture and of the invention. Since many embodiments of the invention can be made without departing from the spirit and scope of the invention, the invention resides in the claims hereinafter appended.

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PCT/US2004/030344 2003-11-10 2004-09-15 Device and method for insertion of a cannula of an infusion device Ceased WO2005046781A1 (en)

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AU2004289185A AU2004289185B2 (en) 2003-11-10 2004-09-15 Device and method for insertion of a cannula of an infusion device
EP04784263.8A EP1691877B1 (en) 2003-11-10 2004-09-15 Device for insertion of a cannula of an infusion device
CA2544303A CA2544303C (en) 2003-11-10 2004-09-15 Device and method for insertion of a cannula of an infusion device
JP2006539475A JP4685024B2 (ja) 2003-11-10 2004-09-15 輸液装置のカニューレ挿入装置

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1764122A1 (de) * 2005-09-15 2007-03-21 F.Hoffmann-La Roche Ag Insertionskopf mit Nadelschutz im Griff
JP2009507583A (ja) * 2005-09-15 2009-02-26 エフ．ホフマン−ラ ロシュ アーゲー ハンドル内に針保護装置を備えた挿入ヘッド
JP2010501281A (ja) * 2006-08-23 2010-01-21 メドトロニック ミニメド インコーポレイテッド 針挿入器を備えた注入媒体送達システム、デバイス、および方法、ならびに針挿入器デバイスおよび方法
US7896844B2 (en) 2005-09-15 2011-03-01 Roche Diagnostics International Ag Insertion head with a handle
EP2596821A1 (en) * 2004-06-16 2013-05-29 Smiths Medical ASD, Inc. Device and method for insertion of a cannula of an infusion device
US8628500B2 (en) 2007-06-25 2014-01-14 Roche Diagnostics Operations Inc. Protector apparatus
USD709767S1 (en) 2013-03-14 2014-07-29 Becton, Dickinson And Company Package portion for a medical product
US9192717B2 (en) 2003-11-10 2015-11-24 Smiths Medical Asd, Inc. Subcutaneous infusion device and device for insertion of a cannula of an infusion device and method
US9744294B2 (en) 2012-03-22 2017-08-29 Terumo Kabushiki Kaisha Puncture device and chemical liquid supplying device
US9943641B2 (en) 2013-03-14 2018-04-17 Becton, Dickinson And Company Package for medical product
EP2613843B1 (en) 2010-09-10 2021-01-27 Mölnlycke Health Care AB Fixation device
US11229753B2 (en) 2016-04-29 2022-01-25 Smiths Medical Asd, Inc. Subcutaneous insertion systems, devices and related methods

Families Citing this family (474)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6648821B2 (en) 2000-01-21 2003-11-18 Medtronic Minimed, Inc. Microprocessor controlled ambulatory medical apparatus with hand held communication device
US8152789B2 (en) 2001-10-23 2012-04-10 Medtronic Minimed, Inc. System and method for providing closed loop infusion formulation delivery
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
US10080529B2 (en) 2001-12-27 2018-09-25 Medtronic Minimed, Inc. System for monitoring physiological characteristics
ITTO20011228A1 (it) 2001-12-28 2003-06-28 Cane Srl Contenitore per ago monouso.
US9486581B2 (en) * 2002-09-11 2016-11-08 Becton, Dickinson And Company Injector device with force lock-out and injection rate limiting mechanisms
US6926694B2 (en) * 2003-05-09 2005-08-09 Medsolve Technologies, Llc Apparatus and method for delivery of therapeutic and/or diagnostic agents
ATE376435T1 (de) * 2003-06-12 2007-11-15 Disetronic Licensing Ag Insertionsvorrichtung für infusionssets
US7309326B2 (en) 2003-11-18 2007-12-18 Icu Medical, Inc. Infusion set
ES2294531T3 (es) * 2003-12-30 2008-04-01 Disetronic Licensing Ag Dispositivo de insercion para dispositivos de perforacion.
US7648494B2 (en) 2004-03-26 2010-01-19 Unomedical A/S Infusion set and injector device for infusion set
US20050273076A1 (en) * 2004-06-07 2005-12-08 C.R. Bard, Inc. Subcutaneous infusion devices
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
US11590286B2 (en) 2004-11-22 2023-02-28 Kaleo, Inc. Devices, systems and methods for medicament delivery
US7947017B2 (en) 2004-11-22 2011-05-24 Intelliject, Inc. Devices, systems and methods for medicament delivery
WO2006083876A2 (en) 2005-02-01 2006-08-10 Intelliject, Llc Devices, systems, and methods for medicament delivery
CA3015269A1 (en) 2004-11-22 2006-06-01 Kaleo, Inc. Devices, systems, and methods for medicament delivery
US7648483B2 (en) 2004-11-22 2010-01-19 Intelliject, Inc. Devices, systems and methods for medicament delivery
US10737028B2 (en) 2004-11-22 2020-08-11 Kaleo, Inc. Devices, systems and methods for medicament delivery
MX2007006840A (es) 2004-12-10 2007-08-14 Unomedical As Insertador.
US8512243B2 (en) 2005-09-30 2013-08-20 Abbott Diabetes Care Inc. Integrated introducer and transmitter assembly and methods of use
US8029441B2 (en) 2006-02-28 2011-10-04 Abbott Diabetes Care Inc. Analyte sensor transmitter unit configuration for a data monitoring and management system
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US10226207B2 (en) 2004-12-29 2019-03-12 Abbott Diabetes Care Inc. Sensor inserter having introducer
US9788771B2 (en) 2006-10-23 2017-10-17 Abbott Diabetes Care Inc. Variable speed sensor insertion devices and methods of use
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
US7621395B2 (en) 2005-06-28 2009-11-24 Unomedical A/S Packing for infusion set and method of applying an infusion set
DE602006005674D1 (de) 2005-07-06 2009-04-23 Vascular Pathways Inc Gerät zur intravenösen kathetereinführung und verwendungsverfahren
EP1762259B2 (en) 2005-09-12 2025-01-01 Unomedical A/S Inserter for an infusion set with a first and second spring units
USD655807S1 (en) 2005-12-09 2012-03-13 Unomedical A/S Medical device
PL1962925T3 (pl) 2005-12-23 2009-10-30 Unomedical As Urządzenie do podawania
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US7892216B2 (en) * 2006-02-07 2011-02-22 Icu Medical, Inc. Infusion set
US9186455B2 (en) * 2006-02-14 2015-11-17 B. Braun Medical Inc. Port access device
CA2642415A1 (en) 2006-02-28 2007-09-07 Unomedical A/S Inserter for infusion part and infusion part provided with needle protector
AU2007256561B2 (en) 2006-06-07 2012-07-19 Unomedical A/S Inserter for transcutaneous sensor
WO2007140785A1 (en) 2006-06-09 2007-12-13 Unomedical A/S Mounting pad
CA2658577A1 (en) 2006-08-02 2008-02-07 Unomedical A/S Cannula and delivery device
DK2054109T3 (en) 2006-08-24 2018-03-19 Hoffmann La Roche INTRODUCTION DEVICE FOR INTRODUCTION HEADS, ESPECIALLY FOR INFUSION KITS
FR2905273B1 (fr) * 2006-09-06 2009-04-03 Becton Dickinson France Soc Pa Dispositif d'injection automatique avec moyen de temporisation.
US9056165B2 (en) 2006-09-06 2015-06-16 Medtronic Minimed, Inc. Intelligent therapy recommendation algorithm and method of using the same
EP1917990A1 (en) 2006-10-31 2008-05-07 Unomedical A/S Infusion set
DK2099384T3 (en) * 2006-11-28 2018-10-08 Hoffmann La Roche IMPLEMENTATION DEVICE AND PROCEDURE FOR INTRODUCING A SUBCUTANT IMPORTANT ELEMENT IN A BODY
CA2677009A1 (en) 2007-02-06 2008-08-14 Glumetrics, Inc. Optical systems and methods for rationmetric measurement of blood glucose concentration
US8738107B2 (en) 2007-05-10 2014-05-27 Medtronic Minimed, Inc. Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement
JP2011516097A (ja) * 2007-04-10 2011-05-26 メディンゴ・リミテッド 液体ポンプ輸送装置及び方法
ATE548972T1 (de) 2007-05-07 2012-03-15 Vascular Pathways Inc Intravenöse kathetereinführungs- und blutprobenvorrichtung
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
AU2008266382B2 (en) 2007-06-20 2013-06-27 Unomedical A/S A catheter and a method and an apparatus for making such catheter
US8160900B2 (en) 2007-06-29 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring and management device and method to analyze the frequency of user interaction with the device
JP2010531692A (ja) 2007-07-03 2010-09-30 ウノメディカル アクティーゼルスカブ 双安定均衡状態を持つ挿入器
JP2011509097A (ja) 2007-07-10 2011-03-24 ウノメディカル アクティーゼルスカブ ２つのスプリングを備えた挿入器
CA2694952A1 (en) 2007-07-18 2009-01-22 Unomedical A/S Insertion device with pivoting action
JP2010538751A (ja) * 2007-09-17 2010-12-16 アイシーユー・メディカル・インコーポレーテッド 注入装置のための挿入装置
DE102007049446A1 (de) * 2007-10-16 2009-04-23 Cequr Aps Katheter-Einführeinrichtung
US10076606B2 (en) * 2007-12-10 2018-09-18 Medtronic Minimed, Inc. Insertion devices, insertion needles, and related methods
PL2252349T3 (pl) 2008-02-13 2012-01-31 Unomedical As Uszczelnienie między częścią kaniulową a drogą przepływu płynu
CA2715667A1 (en) 2008-02-20 2009-08-27 Unomedical A/S Insertion device with horizontally moving part
CA2723291C (en) * 2008-05-14 2017-08-15 Becton, Dickinson And Company Separatable infusion set with cleanable interface and straight line attachment
US8700114B2 (en) 2008-07-31 2014-04-15 Medtronic Minmed, Inc. Analyte sensor apparatuses comprising multiple implantable sensor elements and methods for making and using them
JP5125876B2 (ja) * 2008-08-20 2013-01-23 ニプロ株式会社 挿入装置
GB0815748D0 (en) * 2008-08-29 2008-10-08 Liversidge Barry P Medical needle assembly
US12097357B2 (en) 2008-09-15 2024-09-24 West Pharma. Services IL, Ltd. Stabilized pen injector
US9393369B2 (en) 2008-09-15 2016-07-19 Medimop Medical Projects Ltd. Stabilized pen injector
US9427529B2 (en) 2008-09-15 2016-08-30 Medimop Medical Projects Ltd. Safeguard mechanism for autoinjector needle
CN102256657A (zh) 2008-12-22 2011-11-23 犹诺医药有限公司 包括粘合垫的医疗器械
CA3149758C (en) 2009-01-12 2026-01-13 Becton, Dickinson And Company Infusion set and/or patch pump having at least one of an in-dwelling rigid catheter with flexible features and/or a flexible catheter attachment
US20100198034A1 (en) 2009-02-03 2010-08-05 Abbott Diabetes Care Inc. Compact On-Body Physiological Monitoring Devices and Methods Thereof
WO2011014492A1 (en) 2009-07-29 2011-02-03 Smiths Medical Asd, Inc. Device and method for insertion of a cannula of an infusion device
AU2010277755A1 (en) 2009-07-30 2012-02-02 Unomedical A/S Inserter device with horizontal moving part
MX2012000778A (es) 2009-08-07 2012-07-30 Unomedical As Dispositivo de suministro con sensor y una o mas canulas.
US8547239B2 (en) 2009-08-18 2013-10-01 Cequr Sa Methods for detecting failure states in a medicine delivery device
US8672873B2 (en) 2009-08-18 2014-03-18 Cequr Sa Medicine delivery device having detachable pressure sensing unit
EP2473963A4 (en) 2009-08-31 2014-01-08 Abbott Diabetes Care Inc MEDICAL DEVICES AND METHOD
US8070723B2 (en) 2009-12-31 2011-12-06 Medtronic Minimed, Inc. Activity guard
USD924406S1 (en) 2010-02-01 2021-07-06 Abbott Diabetes Care Inc. Analyte sensor inserter
DK3622883T3 (da) 2010-03-24 2021-07-19 Abbott Diabetes Care Inc Indførerer til medicinsk indretning og fremgangsmåder til at indføre og anvende medicinske indretninger
MX2012011085A (es) 2010-03-30 2012-10-10 Unomedical As Dispositivo medico.
US10384039B2 (en) 2010-05-14 2019-08-20 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components
US9950139B2 (en) 2010-05-14 2018-04-24 C. R. Bard, Inc. Catheter placement device including guidewire and catheter control elements
US11925779B2 (en) 2010-05-14 2024-03-12 C. R. Bard, Inc. Catheter insertion device including top-mounted advancement components
US8932258B2 (en) 2010-05-14 2015-01-13 C. R. Bard, Inc. Catheter placement device and method
US9872971B2 (en) 2010-05-14 2018-01-23 C. R. Bard, Inc. Guidewire extension system for a catheter placement device
US9215995B2 (en) 2010-06-23 2015-12-22 Medtronic Minimed, Inc. Sensor systems having multiple probes and electrode arrays
US11064921B2 (en) 2010-06-29 2021-07-20 Abbott Diabetes Care Inc. Devices, systems and methods for on-skin or on-body mounting of medical devices
EP2433663A1 (en) 2010-09-27 2012-03-28 Unomedical A/S Insertion system
EP2436412A1 (en) 2010-10-04 2012-04-04 Unomedical A/S A sprinkler cannula
US8814831B2 (en) 2010-11-30 2014-08-26 Becton, Dickinson And Company Ballistic microneedle infusion device
US8795234B2 (en) 2010-11-30 2014-08-05 Becton, Dickinson And Company Integrated spring-activated ballistic insertion for drug infusion device
US8795230B2 (en) 2010-11-30 2014-08-05 Becton, Dickinson And Company Adjustable height needle infusion device
US9950109B2 (en) 2010-11-30 2018-04-24 Becton, Dickinson And Company Slide-activated angled inserter and cantilevered ballistic insertion for intradermal drug infusion
US8784383B2 (en) * 2010-11-30 2014-07-22 Becton, Dickinson And Company Insulin pump dermal infusion set having partially integrated mechanized cannula insertion with disposable activation portion
US8628510B2 (en) 2010-12-22 2014-01-14 Medtronic Minimed, Inc. Monitoring the operating health of a force sensor in a fluid infusion device
US8939943B2 (en) 2011-01-26 2015-01-27 Kaleo, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US8627816B2 (en) 2011-02-28 2014-01-14 Intelliject, Inc. Medicament delivery device for administration of opioid antagonists including formulations for naloxone
US9084849B2 (en) 2011-01-26 2015-07-21 Kaleo, Inc. Medicament delivery devices for administration of a medicament within a prefilled syringe
US8690833B2 (en) 2011-01-31 2014-04-08 Vascular Pathways, Inc. Intravenous catheter and insertion device with reduced blood spatter
US9339639B2 (en) 2011-02-22 2016-05-17 Medtronic Minimed, Inc. Sealing assembly for a fluid reservoir of a fluid infusion device
US11266823B2 (en) 2011-02-22 2022-03-08 Medtronic Minimed, Inc. Retractable sealing assembly for a fluid reservoir of a fluid infusion device
EP2678065B1 (en) 2011-02-25 2019-09-11 C.R. Bard Inc. Medical component insertion device including a retractable needle
EP2495001A1 (fr) * 2011-03-03 2012-09-05 Debiotech S.A. Inserteur de canule
WO2012123274A1 (en) 2011-03-14 2012-09-20 Unomedical A/S Inserter system with transport protection
EP2691144B1 (en) 2011-03-30 2017-11-15 Unomedical A/S Subcutaneous inserter device
US9008744B2 (en) 2011-05-06 2015-04-14 Medtronic Minimed, Inc. Method and apparatus for continuous analyte monitoring
US8795231B2 (en) 2011-05-10 2014-08-05 Medtronic Minimed, Inc. Automated reservoir fill system
USD903101S1 (en) 2011-05-13 2020-11-24 C. R. Bard, Inc. Catheter
US10352941B2 (en) 2011-09-27 2019-07-16 Medtronic Minimed, Inc. Method for functionalizing a porous membrane covering of an optical sensor to facilitate coupling of an antithrom-bogenic agent
WO2013050277A1 (en) 2011-10-05 2013-04-11 Unomedical A/S Inserter for simultaneous insertion of multiple transcutaneous parts
EP2583715A1 (en) 2011-10-19 2013-04-24 Unomedical A/S Infusion tube system and method for manufacture
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
US9989522B2 (en) 2011-11-01 2018-06-05 Medtronic Minimed, Inc. Methods and materials for modulating start-up time and air removal in dry sensors
US8999720B2 (en) 2011-11-17 2015-04-07 Medtronic Minimed, Inc. Aqueous radiation protecting formulations and methods for making and using them
CA3043590C (en) 2011-12-07 2021-10-19 Becton, Dickinson And Company Infusion device with releasable fluid connector
CA3012939C (en) 2011-12-07 2020-07-21 Becton, Dickinson And Company Needle shielding assemblies and infusion devices for use therewith
FI3300658T3 (fi) 2011-12-11 2024-03-01 Abbott Diabetes Care Inc Analyyttianturimenetelmiä
KR101621183B1 (ko) * 2011-12-15 2016-05-23 에스에이치엘 그룹 에이비 캡 조립체
US9610401B2 (en) 2012-01-13 2017-04-04 Medtronic Minimed, Inc. Infusion set component with modular fluid channel element
US9931065B2 (en) 2012-04-04 2018-04-03 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
USD685083S1 (en) 2012-04-13 2013-06-25 Becton, Dickinson And Company Infusion device
USD687141S1 (en) 2012-04-13 2013-07-30 Becton, Dickinson And Company Infusion device
USD685084S1 (en) 2012-04-13 2013-06-25 Becton, Dickinson And Company Infusion device
USD687140S1 (en) 2012-04-13 2013-07-30 Becton, Dickinson And Company Infusion device
USD688784S1 (en) 2012-04-13 2013-08-27 Becton, Dickinson And Company Infusion device
USD687536S1 (en) 2012-04-13 2013-08-06 Becton, Dickinson And Company Infusion device
US9522235B2 (en) 2012-05-22 2016-12-20 Kaleo, Inc. Devices and methods for delivering medicaments from a multi-chamber container
US9493807B2 (en) 2012-05-25 2016-11-15 Medtronic Minimed, Inc. Foldover sensors and methods for making and using them
US9645111B2 (en) 2012-06-08 2017-05-09 Medtronic Minimed, Inc. Application of electrochemical impedance spectroscopy in sensor systems, devices, and related methods
US9682188B2 (en) 2012-08-21 2017-06-20 Medtronic Minimed, Inc. Reservoir fluid volume estimator and medical device incorporating same
US9662445B2 (en) 2012-08-30 2017-05-30 Medtronic Minimed, Inc. Regulating entry into a closed-loop operating mode of an insulin infusion system
US10130767B2 (en) 2012-08-30 2018-11-20 Medtronic Minimed, Inc. Sensor model supervisor for a closed-loop insulin infusion system
US9731069B2 (en) 2012-09-27 2017-08-15 Becton, Dickinson And Company Perpendicular infusion set and disposable inserter
US9119528B2 (en) 2012-10-30 2015-09-01 Dexcom, Inc. Systems and methods for providing sensitive and specific alarms
JP6534616B2 (ja) 2012-11-07 2019-06-26 メドトロニック ミニメド インコーポレイテッド 光検体センサの乾燥挿入および１点ｉｎｖｉｖｏ較正
US9265455B2 (en) 2012-11-13 2016-02-23 Medtronic Minimed, Inc. Methods and systems for optimizing sensor function by the application of voltage
US10194840B2 (en) 2012-12-06 2019-02-05 Medtronic Minimed, Inc. Microarray electrodes useful with analyte sensors and methods for making and using them
USD754843S1 (en) 2012-12-07 2016-04-26 Becton, Dickinson And Company Infusion set assembly
USD747459S1 (en) 2012-12-07 2016-01-12 Becton, Dickinson And Company Infusion set assembly
USD747458S1 (en) 2012-12-07 2016-01-12 Becton, Dickinson And Company Infusion set insertion needle assembly
USD756504S1 (en) 2012-12-07 2016-05-17 Becton, Dickinson And Company Infusion set base
USD747456S1 (en) 2012-12-07 2016-01-12 Becton, Dickinson And Company Infusion set assembly
US10426383B2 (en) 2013-01-22 2019-10-01 Medtronic Minimed, Inc. Muting glucose sensor oxygen response and reducing electrode edge growth with pulsed current plating
WO2014120741A1 (en) 2013-01-30 2014-08-07 Vascular Pathways, Inc. Systems and methods for venipuncture and catheter placement
US9338819B2 (en) 2013-05-29 2016-05-10 Medtronic Minimed, Inc. Variable data usage personal medical system and method
US10194864B2 (en) 2013-06-21 2019-02-05 Medtronic Minimed, Inc. Anchoring apparatus and method for attaching device on body
US9880528B2 (en) 2013-08-21 2018-01-30 Medtronic Minimed, Inc. Medical devices and related updating methods and systems
WO2015048799A1 (en) * 2013-09-30 2015-04-02 Medimop Medical Projects Ltd. Needle retraction mechanism for autoinjector
US9265881B2 (en) 2013-10-14 2016-02-23 Medtronic Minimed, Inc. Therapeutic agent injection device
US8979799B1 (en) 2013-10-14 2015-03-17 Medtronic Minimed, Inc. Electronic injector
US9375537B2 (en) 2013-10-14 2016-06-28 Medtronic Minimed, Inc. Therapeutic agent injection device
US8979808B1 (en) 2013-10-14 2015-03-17 Medtronic Minimed, Inc. On-body injector and method of use
US10517892B2 (en) 2013-10-22 2019-12-31 Medtronic Minimed, Inc. Methods and systems for inhibiting foreign-body responses in diabetic patients
US9226709B2 (en) 2013-11-04 2016-01-05 Medtronic Minimed, Inc. ICE message system and method
US9267875B2 (en) 2013-11-21 2016-02-23 Medtronic Minimed, Inc. Accelerated life testing device and method
US9750877B2 (en) 2013-12-11 2017-09-05 Medtronic Minimed, Inc. Predicted time to assess and/or control a glycemic state
US10105488B2 (en) 2013-12-12 2018-10-23 Medtronic Minimed, Inc. Predictive infusion device operations and related methods and systems
US9849240B2 (en) 2013-12-12 2017-12-26 Medtronic Minimed, Inc. Data modification for predictive operations and devices incorporating same
US9649058B2 (en) 2013-12-16 2017-05-16 Medtronic Minimed, Inc. Methods and systems for improving the reliability of orthogonally redundant sensors
US10321844B2 (en) 2013-12-16 2019-06-18 Medtronic Minimed, Inc. In-vivo electrochemical impedance spectroscopy (EIS)-based calibration
US9143941B2 (en) 2013-12-18 2015-09-22 Medtronic Minimed, Inc. Secure communication by user selectable communication range
US9779226B2 (en) 2013-12-18 2017-10-03 Medtronic Minimed, Inc. Fingerprint enhanced authentication for medical devices in wireless networks
US9694132B2 (en) 2013-12-19 2017-07-04 Medtronic Minimed, Inc. Insertion device for insertion set
US9861748B2 (en) 2014-02-06 2018-01-09 Medtronic Minimed, Inc. User-configurable closed-loop notifications and infusion systems incorporating same
USD760891S1 (en) 2014-02-12 2016-07-05 Abbvie Inc. Injection tool
MX2016010376A (es) * 2014-02-12 2017-02-06 Abbvie Inc Herramienta de auto-inyección con protección de aguja móvil.
ES2969056T3 (es) * 2014-03-07 2024-05-16 Bard Inc C R Aparato de estabilización y guía para el acceso a una vía de acceso implantada y métodos relacionados
US9388805B2 (en) 2014-03-24 2016-07-12 Medtronic Minimed, Inc. Medication pump test device and method of use
US9689830B2 (en) 2014-04-03 2017-06-27 Medtronic Minimed, Inc. Sensor detection pads with integrated fuse
US9707336B2 (en) 2014-04-07 2017-07-18 Medtronic Minimed, Inc. Priming detection system and method of using the same
CA2943709C (en) * 2014-04-24 2022-07-05 Becton, Dickinson And Company Catheter insertion device
US10232113B2 (en) 2014-04-24 2019-03-19 Medtronic Minimed, Inc. Infusion devices and related methods and systems for regulating insulin on board
ES2779308T3 (es) 2014-04-24 2020-08-14 Becton Dickinson Co Mecanismo de inserción de catéter para una bomba de parche
US9681828B2 (en) 2014-05-01 2017-06-20 Medtronic Minimed, Inc. Physiological characteristic sensors and methods for forming such sensors
US9901305B2 (en) 2014-06-13 2018-02-27 Medtronic Minimed, Inc. Physiological sensor history backfill system and method
US9517307B2 (en) 2014-07-18 2016-12-13 Kaleo, Inc. Devices and methods for delivering opioid antagonists including formulations for naloxone
US11185627B2 (en) 2014-07-21 2021-11-30 Medtronic Minimed, Inc. Smart connection interface
CH709930A2 (de) 2014-07-29 2016-01-29 Tecpharma Licensing Ag Insertionsvorrichtung für ein Infusionsset.
US9717845B2 (en) 2014-08-19 2017-08-01 Medtronic Minimed, Inc. Geofencing for medical devices
US20160051755A1 (en) 2014-08-25 2016-02-25 Medtronic Minimed, Inc. Low cost fluid delivery device
US10232146B2 (en) 2014-09-05 2019-03-19 C. R. Bard, Inc. Catheter insertion device including retractable needle
US9839753B2 (en) 2014-09-26 2017-12-12 Medtronic Minimed, Inc. Systems for managing reservoir chamber pressure
US10279126B2 (en) 2014-10-07 2019-05-07 Medtronic Minimed, Inc. Fluid conduit assembly with gas trapping filter in the fluid flow path
US9592335B2 (en) 2014-10-20 2017-03-14 Medtronic Minimed, Inc. Insulin pump data acquisition device
US9841014B2 (en) 2014-10-20 2017-12-12 Medtronic Minimed, Inc. Insulin pump data acquisition device and system
US9731067B2 (en) 2014-11-25 2017-08-15 Medtronic Minimed, Inc. Mechanical injection pump and method of use
US9901675B2 (en) 2014-11-25 2018-02-27 Medtronic Minimed, Inc. Infusion set insertion device and method of use
US9636453B2 (en) 2014-12-04 2017-05-02 Medtronic Minimed, Inc. Advance diagnosis of infusion device operating mode viability
US9943645B2 (en) 2014-12-04 2018-04-17 Medtronic Minimed, Inc. Methods for operating mode transitions and related infusion devices and systems
US10307535B2 (en) 2014-12-19 2019-06-04 Medtronic Minimed, Inc. Infusion devices and related methods and systems for preemptive alerting
US9717848B2 (en) 2015-01-22 2017-08-01 Medtronic Minimed, Inc. Data derived pre-bolus delivery
US9872954B2 (en) 2015-03-02 2018-01-23 Medtronic Minimed, Inc. Belt clip
US10307528B2 (en) 2015-03-09 2019-06-04 Medtronic Minimed, Inc. Extensible infusion devices and related methods
EP3274021B1 (en) 2015-03-24 2024-02-14 Kaleo, Inc. Devices and methods for delivering a lyophilized medicament
US10449298B2 (en) 2015-03-26 2019-10-22 Medtronic Minimed, Inc. Fluid injection devices and related methods
US10130757B2 (en) 2015-05-01 2018-11-20 Medtronic Minimed, Inc. Method and system for leakage detection in portable medical devices
USD903100S1 (en) 2015-05-01 2020-11-24 C. R. Bard, Inc. Catheter placement device
US10583244B2 (en) 2015-05-08 2020-03-10 Triple Jump Israel Ltd. Systems, apparatuses and methods for fluid infusion into a body
AU2016260547B2 (en) 2015-05-14 2020-09-03 Abbott Diabetes Care Inc. Compact medical device inserters and related systems and methods
US10213139B2 (en) 2015-05-14 2019-02-26 Abbott Diabetes Care Inc. Systems, devices, and methods for assembling an applicator and sensor control device
SG10202006540RA (en) 2015-05-15 2020-08-28 Bard Inc C R Catheter placement device including an extensible needle safety component
US9999721B2 (en) 2015-05-26 2018-06-19 Medtronic Minimed, Inc. Error handling in infusion devices with distributed motor control and related operating methods
JP6830067B2 (ja) 2015-06-30 2021-02-17 カレオ，インコーポレイテッド プレフィルドシリンジ内の医薬を投与する自動注射器
US10293108B2 (en) 2015-08-21 2019-05-21 Medtronic Minimed, Inc. Infusion devices and related patient ratio adjustment methods
US10463297B2 (en) 2015-08-21 2019-11-05 Medtronic Minimed, Inc. Personalized event detection methods and related devices and systems
US10478557B2 (en) 2015-08-21 2019-11-19 Medtronic Minimed, Inc. Personalized parameter modeling methods and related devices and systems
US10201657B2 (en) 2015-08-21 2019-02-12 Medtronic Minimed, Inc. Methods for providing sensor site rotation feedback and related infusion devices and systems
US10117992B2 (en) 2015-09-29 2018-11-06 Medtronic Minimed, Inc. Infusion devices and related rescue detection methods
US9992818B2 (en) 2015-10-06 2018-06-05 Medtronic Minimed, Inc. Protocol translation device
US11501867B2 (en) 2015-10-19 2022-11-15 Medtronic Minimed, Inc. Medical devices and related event pattern presentation methods
US9757511B2 (en) 2015-10-19 2017-09-12 Medtronic Minimed, Inc. Personal medical device and method of use with restricted mode challenge
US11666702B2 (en) 2015-10-19 2023-06-06 Medtronic Minimed, Inc. Medical devices and related event pattern treatment recommendation methods
US20170112533A1 (en) 2015-10-21 2017-04-27 Dexcom, Inc. Transcutaneous analyte sensors, applicators therefor, and associated methods
US10146911B2 (en) 2015-10-23 2018-12-04 Medtronic Minimed, Inc. Medical devices and related methods and systems for data transfer
US10037722B2 (en) 2015-11-03 2018-07-31 Medtronic Minimed, Inc. Detecting breakage in a display element
US10827959B2 (en) 2015-11-11 2020-11-10 Medtronic Minimed, Inc. Sensor set
PL3377146T3 (pl) 2015-11-20 2021-10-11 Amf Medical Sa Mikropompa i sposób wytwarzania mikropompy
US9848805B2 (en) 2015-12-18 2017-12-26 Medtronic Minimed, Inc. Biostable glucose permeable polymer
US10327680B2 (en) 2015-12-28 2019-06-25 Medtronic Minimed, Inc. Sensor systems, devices, and methods for continuous glucose monitoring
US10327686B2 (en) 2015-12-28 2019-06-25 Medtronic Minimed, Inc. Sensor systems, devices, and methods for continuous glucose monitoring
US10349872B2 (en) 2015-12-28 2019-07-16 Medtronic Minimed, Inc. Methods, systems, and devices for sensor fusion
US20170184527A1 (en) 2015-12-28 2017-06-29 Medtronic Minimed, Inc. Sensor systems, devices, and methods for continuous glucose monitoring
US20170181672A1 (en) 2015-12-28 2017-06-29 Medtronic Minimed, Inc. Sensor systems, devices, and methods for continuous glucose monitoring
ES2976108T3 (es) 2015-12-30 2024-07-23 Dexcom Inc Sistemas y métodos de sensor de analito transcutáneo
CN109068983B (zh) 2016-01-28 2021-03-23 克鲁有限公司 用于跟踪食物摄入和其它行为并提供相关反馈的方法和设备
US10790054B1 (en) 2016-12-07 2020-09-29 Medtronic Minimed, Inc. Method and apparatus for tracking of food intake and other behaviors and providing relevant feedback
US20230368046A9 (en) 2016-01-28 2023-11-16 Medtronic Minimed, Inc. Activation of Ancillary Sensor Systems Based on Triggers from a Wearable Gesture Sensing Device
EP4491116A3 (en) 2016-02-05 2025-03-19 Roche Diabetes Care GmbH Medical device for detecting at least one analyte in a body fluid
LT4233720T (lt) 2016-02-05 2024-09-25 F. Hoffmann-La Roche Ag Medicinos prietaisas, skirtas bent vienai medžiagai kūno skystyje aptikti
US10765348B2 (en) 2016-04-08 2020-09-08 Medtronic Minimed, Inc. Sensor and transmitter product
US10765369B2 (en) 2016-04-08 2020-09-08 Medtronic Minimed, Inc. Analyte sensor
US10413183B2 (en) 2016-04-08 2019-09-17 Medtronic Minimed, Inc. Insertion device
US12419547B2 (en) 2016-04-08 2025-09-23 Medtronic Minimed, Inc. Sensor and transmitter product
US10589038B2 (en) 2016-04-27 2020-03-17 Medtronic Minimed, Inc. Set connector systems for venting a fluid reservoir
US9970893B2 (en) 2016-04-28 2018-05-15 Medtronic Minimed, Inc. Methods, systems, and devices for electrode capacitance calculation and application
US10426389B2 (en) 2016-04-28 2019-10-01 Medtronic Minimed, Inc. Methods, systems, and devices for electrode capacitance calculation and application
US10324058B2 (en) 2016-04-28 2019-06-18 Medtronic Minimed, Inc. In-situ chemistry stack for continuous glucose sensors
US10086134B2 (en) 2016-05-26 2018-10-02 Medtronic Minimed, Inc. Systems for set connector assembly with lock
US9968737B2 (en) 2016-05-26 2018-05-15 Medtronic Minimed, Inc. Systems for set connector assembly with lock
US10086133B2 (en) 2016-05-26 2018-10-02 Medtronic Minimed, Inc. Systems for set connector assembly with lock
USD806862S1 (en) 2016-06-06 2018-01-02 Medsource International Llc Safety I.V. catheter
US11134872B2 (en) 2016-06-06 2021-10-05 Medtronic Minimed, Inc. Thermally stable glucose limiting membrane for glucose sensors
US11179078B2 (en) 2016-06-06 2021-11-23 Medtronic Minimed, Inc. Polycarbonate urea/urethane polymers for use with analyte sensors
WO2018026385A1 (en) 2016-08-01 2018-02-08 Medimop Medical Projects Ltd. Partial door closure prevention spring
US10449291B2 (en) 2016-09-06 2019-10-22 Medtronic Minimed, Inc. Pump clip for a fluid infusion device
CN109715093B (zh) 2016-09-12 2020-11-06 C·R·巴德股份有限公司 导管插入装置的血液控制
WO2018081632A1 (en) 2016-10-27 2018-05-03 C.R. Bard, Inc. Intraosseous access device
US10709834B2 (en) 2016-12-21 2020-07-14 Medtronic Minimed, Inc. Medication fluid infusion set component with integrated physiological analyte sensor, and corresponding fluid infusion device
US10854324B2 (en) 2016-12-21 2020-12-01 Medtronic Minimed, Inc. Infusion systems and methods for prospective closed-loop adjustments
US10272201B2 (en) 2016-12-22 2019-04-30 Medtronic Minimed, Inc. Insertion site monitoring methods and related infusion devices and systems
WO2018119218A1 (en) 2016-12-23 2018-06-28 Kaleo, Inc. Medicament delivery device and methods for delivering drugs to infants and children
US11197949B2 (en) 2017-01-19 2021-12-14 Medtronic Minimed, Inc. Medication infusion components and systems
US10821225B2 (en) 2017-01-20 2020-11-03 Medtronic Minimed, Inc. Cannulas for drug delivery devices
CA3050721A1 (en) 2017-01-23 2018-07-26 Abbott Diabetes Care Inc. Systems, devices and methods for analyte sensor insertion
US10552580B2 (en) 2017-02-07 2020-02-04 Medtronic Minimed, Inc. Infusion system consumables and related calibration methods
JP7287891B2 (ja) 2017-02-16 2023-06-06 エンベクタ コーポレイション ペンニードルハブの注射深さの最適化
US10646649B2 (en) 2017-02-21 2020-05-12 Medtronic Minimed, Inc. Infusion devices and fluid identification apparatuses and methods
AU2017401073B2 (en) 2017-03-01 2022-06-02 C. R. Bard, Inc. Catheter insertion device
US20180249935A1 (en) 2017-03-06 2018-09-06 Medtronic Minimed, Inc. Colorometric sensor for the non-invasive screening of glucose in sweat in pre and type 2 diabetes
US11134868B2 (en) 2017-03-17 2021-10-05 Medtronic Minimed, Inc. Metal pillar device structures and methods for making and using them in electrochemical and/or electrocatalytic applications
US11000236B2 (en) 2017-03-24 2021-05-11 Medtronic Minimed, Inc. Patient data management systems and conversational interaction methods
CN115644863A (zh) 2017-05-03 2023-01-31 雅培糖尿病护理公司 具有传感器数据的基于持续期的调整的系统、装置及方法
US11512384B2 (en) 2017-05-11 2022-11-29 Medtronic Minimed, Inc. Analyte sensors and methods for fabricating analyte sensors
CN113855913A (zh) 2017-05-30 2021-12-31 西部制药服务有限公司(以色列) 用于穿戴式注射器的模块化驱动机构
WO2018222011A1 (ko) * 2017-06-02 2018-12-06 주식회사 아이센스 연속 혈당 측정기용 센서 어플리케이터 조립체
WO2018222009A1 (ko) * 2017-06-02 2018-12-06 주식회사 아이센스 연속 혈당 측정기용 센서 어플리케이터 조립체
WO2018222010A1 (ko) * 2017-06-02 2018-12-06 주식회사 아이센스 연속 혈당 측정기용 센서 어플리케이터 조립체
KR102164781B1 (ko) 2017-06-02 2020-10-15 주식회사 아이센스 연속 혈당 측정기용 센서 어플리케이터 조립체
WO2018229783A1 (en) 2017-06-15 2018-12-20 Triple Jump Israel Ltd. Patch pump systems and apparatus for managing diabetes, and methods thereof
KR102933948B1 (ko) 2017-06-23 2026-03-03 덱스콤, 인크. 경피성 분석 센서, 이를 위한 어플리케이터 및 관련 방법
US10856784B2 (en) 2017-06-30 2020-12-08 Medtronic Minimed, Inc. Sensor initialization methods for faster body sensor response
DE202018006591U1 (de) 2017-08-18 2021-07-21 Abbott Diabetes Care, Inc. Systeme und Vorrichtungen betreffend die individualisierte Kalibrierung und/oder Herstellung von medizinischen Vorrichtungen
US11412960B2 (en) 2017-08-28 2022-08-16 Medtronic Minimed, Inc. Pedestal for sensor assembly packaging and sensor introducer removal
JP2020531191A (ja) * 2017-08-28 2020-11-05 トリプル ジャンプ イスラエル リミテッド 薬物または物質送達のためのシステム、方法、装置およびデバイス
US10596295B2 (en) 2017-08-28 2020-03-24 Medtronic Minimed, Inc. Adhesive patch arrangement for a physiological characteristic sensor, and related sensor assembly
US11311217B2 (en) 2017-09-13 2022-04-26 Medtronic Minimed, Inc. Methods, systems, and devices for calibration and optimization of glucose sensors and sensor output
US10874300B2 (en) 2017-09-26 2020-12-29 Medtronic Minimed, Inc. Waferscale physiological characteristic sensor package with integrated wireless transmitter
US10524730B2 (en) 2017-09-28 2020-01-07 Medtronic Minimed, Inc. Medical devices with microneedle arrays and methods for operating such medical devices
US10525244B2 (en) 2017-09-28 2020-01-07 Medtronic Minimed, Inc. Microneedle arrays and methods for fabricating microneedle arrays
DK3928687T3 (da) 2017-10-24 2024-09-30 Dexcom Inc Bærbar indretning med på forhånd forbundet analytsensor
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
US11676734B2 (en) 2017-11-15 2023-06-13 Medtronic Minimed, Inc. Patient therapy management system that leverages aggregated patient population data
US11529458B2 (en) 2017-12-08 2022-12-20 Amf Medical Sa Drug delivery device
US11471082B2 (en) 2017-12-13 2022-10-18 Medtronic Minimed, Inc. Complex redundancy in continuous glucose monitoring
US11213230B2 (en) 2017-12-13 2022-01-04 Medtronic Minimed, Inc. Optional sensor calibration in continuous glucose monitoring
PT4241684T (pt) 2017-12-21 2025-02-06 Roche Diabetes Care Gmbh Sistema médico e método de fabricação do mesmo
US11439352B2 (en) 2018-01-17 2022-09-13 Medtronic Minimed, Inc. Medical device with adhesive patch longevity
DE102018101283A1 (de) * 2018-01-22 2019-07-25 Eyesense Gmbh Injektor zum transkutanen Einführen eines Sensors in einen Patienten
US12042284B2 (en) 2018-01-23 2024-07-23 Medtronic Minimed, Inc. Implantable polymer surfaces exhibiting reduced in vivo inflammatory responses
EP3743005B1 (en) 2018-01-26 2025-09-03 Bard Peripheral Vascular, Inc. Systems for locating and identifying an implanted medical device
US11186859B2 (en) 2018-02-07 2021-11-30 Medtronic Minimed, Inc. Multilayer electrochemical analyte sensors and methods for making and using them
US11583213B2 (en) 2018-02-08 2023-02-21 Medtronic Minimed, Inc. Glucose sensor electrode design
US11220735B2 (en) 2018-02-08 2022-01-11 Medtronic Minimed, Inc. Methods for controlling physical vapor deposition metal film adhesion to substrates and surfaces
US11389626B2 (en) 2018-03-07 2022-07-19 Bard Access Systems, Inc. Guidewire advancement and blood flashback systems for a medical device insertion system
US11672446B2 (en) 2018-03-23 2023-06-13 Medtronic Minimed, Inc. Insulin delivery recommendations based on nutritional information
US11147919B2 (en) 2018-04-23 2021-10-19 Medtronic Minimed, Inc. Methodology to recommend and implement adjustments to a fluid infusion device of a medication delivery system
US11158413B2 (en) 2018-04-23 2021-10-26 Medtronic Minimed, Inc. Personalized closed loop medication delivery system that utilizes a digital twin of the patient
US20190341149A1 (en) 2018-05-07 2019-11-07 Medtronic Minimed, Inc. Augmented reality guidance for medical devices
CN119924827A (zh) 2018-06-07 2025-05-06 雅培糖尿病护理公司 用于分析物监测系统的聚焦灭菌和已灭菌的子组件
USD926325S1 (en) 2018-06-22 2021-07-27 Dexcom, Inc. Wearable medical monitoring device
USD921884S1 (en) 2018-07-27 2021-06-08 Bard Access Systems, Inc. Catheter insertion device
KR102185833B1 (ko) 2018-07-31 2020-12-03 주식회사 아이센스 연속 혈당 측정 장치
US11761077B2 (en) 2018-08-01 2023-09-19 Medtronic Minimed, Inc. Sputtering techniques for biosensors
US11122697B2 (en) 2018-08-07 2021-09-14 Medtronic Minimed, Inc. Method of fabricating an electronic medical device, including overmolding an assembly with thermoplastic material
US11021731B2 (en) 2018-08-23 2021-06-01 Medtronic Minimed, Inc. Analyte sensing layers, analyte sensors and methods for fabricating the same
US10828419B2 (en) 2018-09-04 2020-11-10 Medtronic Minimed, Inc. Infusion set with pivoting metal cannula and strain relief
US11547799B2 (en) 2018-09-20 2023-01-10 Medtronic Minimed, Inc. Patient day planning systems and methods
CN112292166B (zh) * 2018-09-22 2023-02-21 艾斯曲尔医疗公司 注射器针头插入和缩回组件
US10894126B2 (en) 2018-09-28 2021-01-19 Medtronic Minimed, Inc. Fluid infusion system that automatically determines and delivers a correction bolus
US10980942B2 (en) 2018-09-28 2021-04-20 Medtronic Minimed, Inc. Infusion devices and related meal bolus adjustment methods
US11071821B2 (en) 2018-09-28 2021-07-27 Medtronic Minimed, Inc. Insulin infusion device with efficient confirmation routine for blood glucose measurements
US11097052B2 (en) 2018-09-28 2021-08-24 Medtronic Minimed, Inc. Insulin infusion device with configurable target blood glucose value for automatic basal insulin delivery operation
US20200116748A1 (en) 2018-10-11 2020-04-16 Medtronic Minimed, Inc. Systems and methods for measurement of fluid delivery
US10946140B2 (en) 2018-10-11 2021-03-16 Medtronic Minimed, Inc. Systems and methods for measurement of fluid delivery
US20200289373A1 (en) 2018-10-31 2020-09-17 Medtronic Minimed, Inc. Automated detection of a physical behavior event and corresponding adjustment of a physiological characteristic sensor device
US20200135320A1 (en) 2018-10-31 2020-04-30 Medtronic Minimed, Inc. Automated detection of a physical behavior event and corresponding adjustment of a medication dispensing system based on historical events
US11363986B2 (en) 2018-10-31 2022-06-21 Medtronic Minimed, Inc. Automated detection of a physical behavior event and corresponding adjustment of a medication dispensing system
US11367517B2 (en) 2018-10-31 2022-06-21 Medtronic Minimed, Inc. Gesture-based detection of a physical behavior event based on gesture sensor data and supplemental information from at least one external source
US11382541B2 (en) 2018-11-16 2022-07-12 Medtronic Minimed, Inc. Miniaturized analyte sensor
US11540750B2 (en) 2018-12-19 2023-01-03 Medtronic Minimed, Inc Systems and methods for physiological characteristic monitoring
CN113195022A (zh) 2018-12-21 2021-07-30 雅培糖尿病护理公司 用于分析物传感器插入的系统、装置和方法
US12478739B2 (en) 2018-12-29 2025-11-25 Kaleo, Inc. Devices and methods for delivery of substances within a prefilled syringe
US20220096740A1 (en) * 2019-01-30 2022-03-31 Asahi Polyslider Company, Limited Cannula inserter
US12114972B2 (en) 2019-02-01 2024-10-15 Medtronic Minimed, Inc. Methods, systems, and devices for continuous glucose monitoring
US12156988B2 (en) 2019-02-01 2024-12-03 Medtronic Minimed, Inc. Methods and devices for occlusion detection using actuator sensors
US11389587B2 (en) 2019-02-06 2022-07-19 Medtronic Minimed, Inc. Patient monitoring systems and related presentation methods
US20200253513A1 (en) 2019-02-12 2020-08-13 Medtronic Minimed, Inc. Miniaturized noninvasive glucose sensor and continuous glucose monitoring system
US12082910B2 (en) 2019-02-12 2024-09-10 Medtronic Minimed, Inc. Miniaturized noninvasive glucose sensor and continuous glucose monitoring system
US12507914B2 (en) 2019-02-12 2025-12-30 Medtronic Minimed, Inc. Miniaturized noninvasive glucose sensor and continuous glucose monitoring system
US11191899B2 (en) 2019-02-12 2021-12-07 Medtronic Minimed, Inc. Infusion systems and related personalized bolusing methods
EP4643903A3 (en) 2019-02-22 2026-01-14 DEKA Products Limited Partnership Inserter assembly for infusion sets
US12539361B2 (en) 2019-02-22 2026-02-03 Deka Products Limited Partnership Infusion set and inserter assembly apparatuses, systems, and methods
US11311215B2 (en) 2019-04-04 2022-04-26 Medtronic Minimed, Inc. Measurement of device materials using non-Faradaic electrochemical impedance spectroscopy
US11986629B2 (en) 2019-06-11 2024-05-21 Medtronic Minimed, Inc. Personalized closed loop optimization systems and methods
US12588843B2 (en) 2019-04-22 2026-03-31 Medtronic Minimed, Inc. Sensor with substrate including integrated electrical and chemical components and methods for fabricating the same
US11224361B2 (en) 2019-04-23 2022-01-18 Medtronic Minimed, Inc. Flexible physiological characteristic sensor assembly
US11317867B2 (en) 2019-04-23 2022-05-03 Medtronic Minimed, Inc. Flexible physiological characteristic sensor assembly
US10939488B2 (en) 2019-05-20 2021-03-02 Medtronic Minimed, Inc. Method and system for controlling communication between devices of a wireless body area network for an medical device system
USD1002852S1 (en) 2019-06-06 2023-10-24 Abbott Diabetes Care Inc. Analyte sensor device
US11793930B2 (en) 2019-06-06 2023-10-24 Medtronic Minimed, Inc. Fluid infusion systems
US11448611B2 (en) 2019-07-03 2022-09-20 Medtronic Minimed, Inc. Structurally reinforced sensor and method for manufacturing the same
US11617828B2 (en) 2019-07-17 2023-04-04 Medtronic Minimed, Inc. Reservoir connection interface with detectable signature
US11718865B2 (en) 2019-07-26 2023-08-08 Medtronic Minimed, Inc. Methods to improve oxygen delivery to implantable sensors
US11523757B2 (en) 2019-08-01 2022-12-13 Medtronic Minimed, Inc. Micro-pillar working electrodes design to reduce backflow of hydrogen peroxide in glucose sensor
US12427253B2 (en) * 2019-08-02 2025-09-30 Bionime Corporation Insertion device for a biosensor and insertion method thereof
US12343172B2 (en) * 2019-08-02 2025-07-01 Bionime Corporation Insertion device for a biosensor
TWI729670B (zh) * 2019-08-02 2021-06-01 華廣生技股份有限公司 生物感測器之植入裝置
US20220039755A1 (en) 2020-08-06 2022-02-10 Medtronic Minimed, Inc. Machine learning-based system for estimating glucose values
US11883208B2 (en) 2019-08-06 2024-01-30 Medtronic Minimed, Inc. Machine learning-based system for estimating glucose values based on blood glucose measurements and contextual activity data
US11617522B2 (en) 2019-08-06 2023-04-04 Medtronic Minimed, Inc. Sensor inserter with disposal lockout state
WO2021030210A1 (en) 2019-08-09 2021-02-18 Kaleo, Inc. Devices and methods for delivery of substances within a prefilled syringe
CN213312819U (zh) 2019-08-19 2021-06-01 贝克顿·迪金森公司 中线导管放置装置
US11724045B2 (en) 2019-08-21 2023-08-15 Medtronic Minimed, Inc. Connection of a stopper and piston in a fluid delivery device
US20210060244A1 (en) 2019-08-28 2021-03-04 Medtronic Minimed, Inc. Method and system for verifying whether a non-medical client device is operating correctly with a medical device controlled by the non-medical client device and causing a notification to be generated
US11571515B2 (en) 2019-08-29 2023-02-07 Medtronic Minimed, Inc. Controlling medical device operation and features based on detected patient sleeping status
JP7424680B2 (ja) 2019-09-10 2024-01-30 メドソース・インターナショナル・リミテッド・ライアビリティ・カンパニー 静脈内カテーテルデバイス
US11654235B2 (en) 2019-09-12 2023-05-23 Medtronic Minimed, Inc. Sensor calibration using fabrication measurements
US11565044B2 (en) 2019-09-12 2023-01-31 Medtronic Minimed, Inc. Manufacturing controls for sensor calibration using fabrication measurements
EP4025288A1 (en) 2019-09-20 2022-07-13 Bard Peripheral Vascular, Inc. Intravenous catheter-placement device
US11213623B2 (en) 2019-09-20 2022-01-04 Medtronic Minimed, Inc. Infusion systems and related personalized bolusing methods
US11241537B2 (en) 2019-09-20 2022-02-08 Medtronic Minimed, Inc. Contextual personalized closed-loop adjustment methods and systems
US11759235B2 (en) 2019-09-27 2023-09-19 Bard Access Systems, Inc. Constant-torque intraosseous access devices and methods thereof
WO2021062215A1 (en) 2019-09-27 2021-04-01 Bard Access Systems, Inc. Step needle for intraosseous access device
CN112568976B (zh) 2019-09-27 2025-08-12 巴德阿克塞斯系统股份有限公司 用于骨内进入医疗装置的各种操作机构及其方法
CN212879457U (zh) 2019-09-27 2021-04-06 巴德阿克塞斯系统股份有限公司 自动推进骨内进入装置和骨内进入装置
US11511099B2 (en) 2019-10-08 2022-11-29 Medtronic Minimed, Inc. Apparatus for detecting mating of a cap with a fluid delivery device and method
US12329926B2 (en) 2019-10-10 2025-06-17 Medtronic Minimed, Inc. Adjustable insertion device
US11638545B2 (en) 2019-10-16 2023-05-02 Medtronic Minimed, Inc. Reducing sensor foreign body response via high surface area metal structures
US12315631B2 (en) 2019-11-07 2025-05-27 Medtronic Minimed, Inc. Medical device site monitoring methods and related devices and systems
US11805997B2 (en) * 2019-11-10 2023-11-07 Revedeon, LLC Skin biopsy device
US12263327B2 (en) 2019-11-14 2025-04-01 Medtronic Minimed, Inc. Synergistic features and functions related to operation of a medication delivery system and a meal transaction application
US11496083B2 (en) 2019-11-15 2022-11-08 Medtronic Minimed, Inc. Devices and methods for controlling electromechanical actuators
US11944784B2 (en) 2019-11-18 2024-04-02 Medtronic Minimed, Inc. Combined analyte sensor and infusion set
US12247941B2 (en) 2019-11-21 2025-03-11 Medtronic Minimed, Inc. Glucose biosensor encasement, glucose biosensor package, and method
US11324881B2 (en) 2019-11-21 2022-05-10 Medtronic Minimed, Inc. Systems for wearable infusion port and associated pump
US11559624B2 (en) 2019-11-21 2023-01-24 Medtronic Minimed, Inc. Systems for wearable infusion port and associated pump
US12610742B2 (en) 2019-11-25 2026-04-21 Aita Bio Inc. Micropump and method of fabricating the same
US12119119B2 (en) 2019-12-09 2024-10-15 Medtronic Minimed, Inc. Methods and systems for real-time sensor measurement simulation
US20210178063A1 (en) 2019-12-13 2021-06-17 Medtronic Minimed, Inc. Controlling medication delivery system operation and features based on automatically detected user stress level
US11488700B2 (en) 2019-12-13 2022-11-01 Medtronic Minimed, Inc. Medical device configuration procedure guidance responsive to detected gestures
US12133969B2 (en) 2019-12-13 2024-11-05 Medtronic Minimed, Inc. Translating therapy parameters of an insulin therapy system to translated therapy parameters for use at a different insulin therapy system
US11786655B2 (en) 2019-12-13 2023-10-17 Medtronic Minimed, Inc. Context-sensitive predictive operation of a medication delivery system in response to gesture-indicated activity changes
US20210183491A1 (en) 2019-12-13 2021-06-17 Medtronic Minimed, Inc. Method and system for training a mathematical model based on labeled events and/or labeled event combinations
US11938301B2 (en) 2019-12-13 2024-03-26 Medtronic Minimed, Inc. Controlling medication delivery system operation and features based on automatically detected muscular movements
US12478286B2 (en) 2019-12-13 2025-11-25 Medtronic Minimed, Inc. Synergistic features and functions related to operation of a medication delivery system and a physical activity detection system
US11690573B2 (en) 2019-12-18 2023-07-04 Medtronic Minimed, Inc. Systems for skin patch gravity resistance
US11375955B2 (en) 2019-12-18 2022-07-05 Medtronic Minimed, Inc. Systems for skin patch gravity resistance
US11821022B2 (en) 2019-12-23 2023-11-21 Medtronic Minimed, Inc. Ethylene oxide absorption layer for analyte sensing and method
US11244753B2 (en) 2020-01-30 2022-02-08 Medtronic Minimed, Inc. Activity monitoring systems and methods
US11957488B2 (en) 2020-02-07 2024-04-16 Medtronic Minimed, Inc. Systems for medical device breathability
US12186098B2 (en) 2020-02-07 2025-01-07 Medtronic Minimed, Inc. Systems for medical device breathability
US12167869B2 (en) 2020-02-28 2024-12-17 Bard Access Systems, Inc. Flexible intraosseous obturator
US11833327B2 (en) 2020-03-06 2023-12-05 Medtronic Minimed, Inc. Analyte sensor configuration and calibration based on data collected from a previously used analyte sensor
USD958167S1 (en) 2020-03-23 2022-07-19 Companion Medical, Inc. Display screen with graphical user interface
US12191017B2 (en) 2020-03-23 2025-01-07 Medtronic Minimed, Inc. Systems and methods for medicine administration and tracking
USD958817S1 (en) 2020-03-31 2022-07-26 Medtronic Minimed, Inc. Display screen with graphical user interface
US11596359B2 (en) 2020-04-09 2023-03-07 Medtronic Minimed, Inc. Methods and systems for mitigating sensor error propagation
CN113520512B (zh) 2020-04-21 2026-01-02 巴德阿克塞斯系统股份有限公司 可重复使用的推动启动式骨内进入装置
US11583631B2 (en) 2020-04-23 2023-02-21 Medtronic Minimed, Inc. Intuitive user interface features and related functionality for a therapy delivery system
US11690955B2 (en) 2020-04-23 2023-07-04 Medtronic Minimed, Inc. Continuous analyte sensor quality measures and related therapy actions for an automated therapy delivery system
US20210377726A1 (en) 2020-05-27 2021-12-02 Medtronic Minimed, Inc. Method and system for automatically associating a non-medical device with a medical device
CN215606058U (zh) 2020-06-03 2022-01-25 巴德阿克塞斯系统股份有限公司 配置用于与骨内进入系统一起使用的闭塞器组件
US12213782B2 (en) 2020-06-04 2025-02-04 Medtronic Minimed, Inc. Physiological characteristic sensor system
US12433538B2 (en) 2020-06-04 2025-10-07 Medtronic Minimed, Inc. Liner for adhesive skin patch
US11272884B2 (en) 2020-06-04 2022-03-15 Medtronic Minimed, Inc. Liner for adhesive skin patch
WO2021247039A1 (en) * 2020-06-05 2021-12-09 Garwood Medical Devices, Llc Subdermal needle electrode apparatus for biofilm infection control
US12064236B2 (en) 2020-06-11 2024-08-20 Medtronic Minimed, Inc. Methods, systems, and devices for improved sensors for continuous glucose monitoring
US20210393876A1 (en) 2020-06-19 2021-12-23 Medtronic Minimed, Inc. Default carbohydrate consumption counts based on characteristics of persons
US12226123B2 (en) 2020-07-17 2025-02-18 Bard Access Systems, Inc. Safety mechanism
US12335342B2 (en) 2020-07-21 2025-06-17 Abbott Diabetes Care Inc. Transmitting analyte data using low-power instruction sets
US11650248B2 (en) 2020-07-28 2023-05-16 Medtronic Minimed, Inc. Electrical current measurement system
US11960311B2 (en) 2020-07-28 2024-04-16 Medtronic Minimed, Inc. Linear voltage regulator with isolated supply current
US12082924B2 (en) 2020-07-31 2024-09-10 Medtronic Minimed, Inc. Sensor identification and integrity check design
US11445807B2 (en) 2020-07-31 2022-09-20 Medtronic Minimed, Inc. Pump clip with tube clamp for a fluid infusion device
CN114098918B (zh) 2020-08-25 2025-12-12 巴德阿克塞斯系统股份有限公司 成角度的骨内进入系统
CA3188510A1 (en) 2020-08-31 2022-03-03 Vivek S. RAO Systems, devices, and methods for analyte sensor insertion
EP4203821B1 (en) 2020-09-01 2025-10-29 Bard Access Systems, Inc. Retractable intraosseous access system
CN215839325U (zh) 2020-09-09 2022-02-18 巴德阿克塞斯系统股份有限公司 用于骨内进入系统的抽吸设备
CA3186905A1 (en) 2020-09-15 2022-03-24 Abbott Diabetes Care Inc. Systems, devices, and methods for an analyte sensor
US12569168B2 (en) 2020-09-15 2026-03-10 Abbott Diabetes Care Inc. Systems, devices, and methods for analyte monitoring
EP3973870A1 (en) * 2020-09-25 2022-03-30 Roche Diabetes Care GmbH Insertion device and method for inserting a medical device
US11839743B2 (en) 2020-10-07 2023-12-12 Medtronic Minimed, Inc. Graphic user interface for automated infusate delivery
US11737783B2 (en) 2020-10-16 2023-08-29 Medtronic Minimed, Inc. Disposable medical device introduction system
US11844930B2 (en) 2020-10-29 2023-12-19 Medtronic Minimed, Inc. User-mountable electronic device with accelerometer-based activation feature
US11806503B2 (en) 2020-10-29 2023-11-07 Medtronic Minimed, Inc. Removable wearable device and related attachment methods
US11534086B2 (en) 2020-10-30 2022-12-27 Medtronic Minimed, Inc. Low-profile wearable medical device
US11951281B2 (en) 2020-11-11 2024-04-09 Medtronic Minimed, Inc. Fluid conduit insertion devices
US12447269B2 (en) 2020-11-11 2025-10-21 Medtronic Minimed, Inc. Torsional insertion devices
US11241530B1 (en) 2020-11-23 2022-02-08 Amf Medical Sa Insulin patch pump having photoplethysmography module
AU2020478795B2 (en) 2020-11-24 2025-09-25 Bard Peripheral Vascular, Inc. Access needle indication systems for locating and accessing subcutaneous medical devices
WO2022119788A1 (en) 2020-12-01 2022-06-09 Medtronic Minimed, Inc. Systems and methods for optimizing medicament dosing
USD999913S1 (en) 2020-12-21 2023-09-26 Abbott Diabetes Care Inc Analyte sensor inserter
EP4271271A4 (en) 2020-12-31 2025-02-26 Abbott Diabetes Care, Inc. EMBEDDED SYSTEMS IN MEDICAL MONITORING SYSTEMS
US12138047B2 (en) 2021-01-22 2024-11-12 Medtronic Minimed, Inc. Micro models and layered prediction models for estimating sensor glucose values and reducing sensor glucose signal blanking
US12423490B2 (en) 2021-01-29 2025-09-23 Medtronic Minimed, Inc. Model mosaic framework for modeling glucose sensitivity
US11998330B2 (en) 2021-01-29 2024-06-04 Medtronic Minimed, Inc. Interference rejection membranes useful with analyte sensors
US11957490B2 (en) 2021-02-02 2024-04-16 Medtronic Minimed, Inc. Dynamic adjustments of physiological data
CN217960227U (zh) 2021-02-08 2022-12-06 巴德阿克塞斯系统股份有限公司 骨内进入系统
US12268847B1 (en) 2021-02-10 2025-04-08 Kaleo, Inc. Devices and methods for delivery of substances within a medicament container
WO2022172281A1 (en) 2021-02-10 2022-08-18 Neeraj Gupta Intravenous cannula
US11883070B2 (en) * 2021-04-13 2024-01-30 Erick Anderson Needle removal device for intraosseous infusion
US12337123B2 (en) 2021-05-06 2025-06-24 Medsource Labs, Llc Safety intravenous cannula
US12569199B2 (en) 2021-05-20 2026-03-10 Medtronic Minimed, Inc. Skin adhesive patch with refreshable perimeter, and related device assembly
US11679199B2 (en) 2021-06-01 2023-06-20 Amf Medical Sa Systems and methods for delivering microdoses of medication
US11857757B2 (en) 2021-06-01 2024-01-02 Tandem Diabetes Care Switzerland Sàrl Systems and methods for delivering microdoses of medication
US12594377B2 (en) 2021-06-01 2026-04-07 Tandem Diabetes Care Switzerland Sàrl Systems and methods for delivering microdoses of medication
US11541169B2 (en) 2021-06-01 2023-01-03 Amf Medical Sa Applicators for systems and methods for delivering microdoses of medication
US11904146B2 (en) 2021-06-08 2024-02-20 Medtronic Minimed, Inc. Medicine injection devices, systems, and methods for medicine administration and tracking
US12214173B2 (en) 2021-06-08 2025-02-04 Medtronic Minimed, Inc. Injection pens for medicine administration and tracking
US12478742B2 (en) 2021-06-09 2025-11-25 Medtronic Minimed, Inc. Injection pens for medicine administration
US11792714B2 (en) 2021-06-16 2023-10-17 Medtronic Minimed, Inc. Medicine administration in dynamic networks
US12370320B2 (en) 2021-06-21 2025-07-29 Medtronic Minimed, Inc. Accessory devices, systems, and methods for medicine administration and tracking
US12433515B2 (en) 2021-08-13 2025-10-07 Medtronic Minimed, Inc. Dry electrochemical impedance spectroscopy metrology for conductive chemical layers
CN119791653A (zh) * 2021-08-26 2025-04-11 深圳硅基传感科技有限公司 施加装置
USD1107897S1 (en) 2021-08-26 2025-12-30 Deka Products Limited Partnership Infusion set component and adhering assembly combination
MX2024002404A (es) * 2021-08-26 2024-06-19 Deka Products Lp Equipo de infusión y aparatos, sistemas, y métodos de montaje de insertador.
USD1013864S1 (en) 2021-08-26 2024-02-06 Deka Products Limited Partnership Fluid administration apparatus assembly
US11587742B1 (en) 2021-09-02 2023-02-21 Medtronic Minimed, Inc. Ingress-tolerant input devices
US11817285B2 (en) 2021-09-02 2023-11-14 Medtronic Minimed, Inc. Ingress-tolerant input devices comprising sliders
EP4402587A2 (en) 2021-09-15 2024-07-24 Abbott Diabetes Care, Inc. Modular analyte connectivity system for extendible communication with different types of physiological sensors
WO2023055914A1 (en) 2021-09-29 2023-04-06 Abbott Diabetes Care Inc. Mobile application updates for analyte data receiving devices
US12201421B2 (en) 2021-10-08 2025-01-21 Medtronic Minimed, Inc. Immunosuppressant releasing coatings
US12442786B2 (en) 2021-10-14 2025-10-14 Medtronic Minimed, Inc. Sensors for 3-hydroxybutyrate detection
US12527500B2 (en) 2021-12-02 2026-01-20 Medtronic Minimed, Inc. Ketone limiting membrane and dual layer membrane approach for ketone sensing
US12186497B2 (en) 2022-01-14 2025-01-07 Medsource International Llc Intravenous cannula
US11896447B2 (en) 2022-03-14 2024-02-13 Medtronic Minimed, Inc. Safeguards against separation from portable medicine delivery devices
US12502486B2 (en) 2022-03-14 2025-12-23 Medtronic Minimed, Inc. Safeguards against usage of incorrect portable medicine delivery devices
US12011293B2 (en) 2022-04-26 2024-06-18 Medtronic Minimed, Inc. Energy management based on a closed switch configuration
US11997806B2 (en) 2022-04-26 2024-05-28 Medtronic Minimed, Inc. Energy management based on an open switch configuration
US12551148B2 (en) 2022-05-27 2026-02-17 Medtronic Minimed, Inc. Systems and methods for compensating for agent elution
CN115300069B (zh) * 2022-06-06 2025-07-11 乐普（北京）医疗器械股份有限公司 一种套管回针装置的驱动机构及套管回针装置
JP2025527479A (ja) * 2022-08-19 2025-08-22 エスディ バイオセンサー，インク 分析物モニタリングデバイスを挿入するための挿入装置組立体
USD1057941S1 (en) 2022-08-26 2025-01-14 Deka Products Limited Partnership Patient care assembly component
USD1090862S1 (en) 2022-08-26 2025-08-26 Deka Products Limited Partnership Adhering assembly for medical devices and the like
USD1043976S1 (en) 2022-08-26 2024-09-24 Deka Products Limited Partnership Fluid transfer connector
US12522853B2 (en) 2022-10-28 2026-01-13 Medtronic Minimed, Inc. Enzyme mediator functionalized polymers for use with analyte sensors

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5451210A (en) 1991-04-29 1995-09-19 Lifequest Medical, Inc. System and method for rapid vascular drug delivery
US5545143A (en) 1993-01-21 1996-08-13 T. S. I. Medical Device for subcutaneous medication delivery
WO1996032981A1 (en) 1995-04-17 1996-10-24 Med Design Corporation Safety stylet for intravenous catheter insertion
US5817058A (en) 1996-12-23 1998-10-06 Shaw; Thomas J. Retractable catheter introducer structure
WO2002081012A2 (de) 2001-04-06 2002-10-17 Disetronic Licensing Ag Infusionsset
US6620136B1 (en) 1999-02-18 2003-09-16 Medsafe Technologies, Llc Retractable I-V catheter placement device

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US53889A (en) * 1866-04-10 Improvement in watchmen s registers
US125669A (en) * 1872-04-16 Improvement in permutation locks
US225373A (en) * 1880-03-09 Water-wheel
US130619A (en) * 1872-08-20 Improvement in vegetable-cutters
US45867A (en) * 1865-01-10 Improved
US60781A (en) * 1867-01-01 Improved process foe finishing sheet metal
US173769A (en) * 1876-02-22 Improvement in condensers for fumes of mercury
US77599A (en) * 1868-05-05 Improvement in stbaw-cutter
US225374A (en) * 1880-03-09 higginbottom
US158520A (en) * 1875-01-05 Improvement in flour-bolts
US2682A (en) * 1842-06-22 Sekaphiwe
US199823A (en) * 1878-01-29 Improvement in metallurgic crucibles
US161332A (en) * 1875-03-30 Improvement in combined tippets and muffs
US109829A (en) * 1870-12-06 Improvement in steam-boilers
US3547119A (en) 1967-12-08 1970-12-15 Baxter Laboratories Inc Catheter assembly
US4531937A (en) 1983-01-24 1985-07-30 Pacesetter Systems, Inc. Introducer catheter apparatus and method of use
US4755173A (en) 1986-02-25 1988-07-05 Pacesetter Infusion, Ltd. Soft cannula subcutaneous injection set
CA1272423A (en) 1986-02-25 1990-08-07 Peter C. Lord Soft cannula subcutaneous injection set and method of making same
US4747831A (en) 1987-04-29 1988-05-31 Phase Medical, Inc. Cannula insertion set with safety retracting needle
US4805791A (en) * 1988-05-04 1989-02-21 Continental White Cap, Inc. Band with lock ring for tamper-evident cap
ATE108675T1 (de) * 1989-05-17 1994-08-15 Vetter & Co Apotheker Spritze für medizinische zwecke.
US4994042A (en) 1989-10-02 1991-02-19 Vadher Dinesh L Combined catheter and needle
GB8926825D0 (en) 1989-11-28 1990-01-17 Glaxo Group Ltd Device
US5129884A (en) 1990-01-16 1992-07-14 Dysarz Edward D Trap in barrel one handed retracted intervenous catheter device
IE911031A1 (en) 1990-04-03 1991-10-23 Knutson Richard A Closed system intravenous catheter
US5176662A (en) 1990-08-23 1993-01-05 Minimed Technologies, Ltd. Subcutaneous injection set with improved cannula mounting arrangement
US5092853A (en) 1991-02-04 1992-03-03 Couvertier Ii Douglas Automatic retractable medical needle and method
US5176643A (en) * 1991-04-29 1993-01-05 George C. Kramer System and method for rapid vascular drug delivery
US5645076A (en) 1991-08-14 1997-07-08 Yoon; Inbae Automatic retractable safety penetrating instrument
US5176650A (en) 1992-02-10 1993-01-05 Haining Michael L Intravenous catheter and insertion device
DK25793A (da) 1993-03-09 1994-09-10 Pharma Plast Int As Infusionssæt til intermitterende eller kontinuerlig indgivelse af et terapeutisk middel
US5257980A (en) 1993-04-05 1993-11-02 Minimed Technologies, Ltd. Subcutaneous injection set with crimp-free soft cannula
CA2132277C (en) 1993-10-22 2005-05-10 Giorgio Cirelli Injection device
CA2135706C (en) 1993-11-15 1999-06-15 Walter E. Cover Retractable-needle cannula insertion set with refinements to better control leakage, retraction speed, and reuse
US5833666A (en) 1993-11-23 1998-11-10 Uresil Corporation Catheter fixation assembly
US5573510A (en) 1994-02-28 1996-11-12 Isaacson; Dennis R. Safety intravenous catheter assembly with automatically retractable needle
IL109294A (en) 1994-04-12 1998-02-08 Wais Med Ltd Surgical instrument for impact insertion of an intraosseous trocar- needle
US5584813A (en) 1995-06-07 1996-12-17 Minimed Inc. Subcutaneous injection set
US5738641A (en) 1996-07-31 1998-04-14 Watson; Robert L. Blood withdrawal patch
US5851197A (en) 1997-02-05 1998-12-22 Minimed Inc. Injector for a subcutaneous infusion set
US6607509B2 (en) 1997-12-31 2003-08-19 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US20070142776A9 (en) 1997-02-05 2007-06-21 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US7329239B2 (en) 1997-02-05 2008-02-12 Medtronic Minimed, Inc. Insertion device for an insertion set and method of using the same
US6093172A (en) 1997-02-05 2000-07-25 Minimed Inc. Injector for a subcutaneous insertion set
US5968011A (en) 1997-06-20 1999-10-19 Maersk Medical A/S Subcutaneous injection set
US6077244A (en) 1998-04-30 2000-06-20 Mdc Investment Holdings, Inc. Catheter insertion device with retractable needle
WO1999033504A1 (en) 1997-12-31 1999-07-08 Minimed Inc. Insertion device for an insertion set and method of using the same
US6056718A (en) 1998-03-04 2000-05-02 Minimed Inc. Medication infusion set
US6123690A (en) 1998-03-20 2000-09-26 Maersk Medical A/S Subcutaneous infusion device
DE29905072U1 (de) 1998-03-20 1999-09-09 Maersk Medical A/S, Lynge Subkutane Infusionsvorrichtung
US5980506A (en) 1998-03-20 1999-11-09 Mathiasen; Orla Subcutaneous infusion device
US6086575A (en) 1998-03-20 2000-07-11 Maersk Medical A/S Subcutaneous infusion device
GB9808408D0 (en) 1998-04-18 1998-06-17 Owen Mumford Ltd Improvements relating to injection devices
DE19821723C2 (de) 1998-05-14 2000-07-06 Disetronic Licensing Ag Katheterkopf für subkutane Verabreichung eines Wirkstoffs
US6949084B2 (en) 1998-05-14 2005-09-27 Disetronic Licensing Ag Catheter head for subcutaneous administration of an active substance
US6736797B1 (en) 1998-06-19 2004-05-18 Unomedical A/S Subcutaneous infusion set
US6355021B1 (en) 1998-07-14 2002-03-12 Maersk Medical A/S Medical puncturing device
US6547762B1 (en) 1999-05-13 2003-04-15 Mdc Investment Holdings, Inc. Retractable needle medical device
JP4383572B2 (ja) * 1999-03-05 2009-12-16 メディキット株式会社 安全留置針
US6450992B1 (en) 1999-07-02 2002-09-17 Smith & Nephew, Inc. Cannula interface
US6572586B1 (en) 2000-07-25 2003-06-03 Animas Corporation Low profile infusion set
US6986760B2 (en) 2000-08-02 2006-01-17 Becton, Dickinson And Company Pen needle and safety shield system
US7052483B2 (en) 2000-12-19 2006-05-30 Animas Corporation Transcutaneous inserter for low-profile infusion sets
US6579267B2 (en) 2001-01-05 2003-06-17 Applied Diabetes Research, Inc. Pivoting joint infusion assembly
JP4387105B2 (ja) 2001-03-04 2009-12-16 アイシーユー・メディカル・インコーポレーテッド インフュージョンハブアセンブリおよび流体ライン切断システム
US20020161332A1 (en) 2001-04-13 2002-10-31 Kirk Ramey Infusion set with tape
EP2140891B1 (en) 2001-05-18 2013-03-27 DEKA Products Limited Partnership Conduit for coupling to a fluid delivery device
CA2446585A1 (en) 2001-06-08 2002-12-19 Grant Richard Wilson Needle hiding assembly for a medication injector
AUPR568901A0 (en) 2001-06-14 2001-07-12 Occupational & Medical Innovations Ltd A retractable needle assembly for a catheter and which uses an elastomeric member to retract the needle
GB0118419D0 (en) 2001-07-28 2001-09-19 Owen Mumford Ltd Improvements relating to injection devices
US20030109829A1 (en) 2001-09-28 2003-06-12 Mogensen Lasse Wesseltoft Injector device for placing a subcutaneous infusion set
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
US7147623B2 (en) 2002-02-12 2006-12-12 Unomedical A/S Infusion device with needle shield
AU2003213638A1 (en) 2002-02-26 2003-09-09 Sterling Medivations, Inc. Insertion device for an insertion set and method of using the same
EP1536855A4 (en) 2002-08-30 2007-09-12 Sterling Medivations Inc ADAPTER FITTING FOR INFUSION EQUIPMENT AND INSERTION SYSTEM
DE20220543U1 (de) 2002-11-29 2003-10-02 Disetronic Licensing Ag, Burgdorf Katheterkopf mit verschließbarem Dichtelement
US7018344B2 (en) 2003-01-21 2006-03-28 Becton, Dickinson And Company Retractable needle shielding device
US20040158202A1 (en) 2003-02-12 2004-08-12 Soren Jensen Cover
US7070580B2 (en) 2003-04-01 2006-07-04 Unomedical A/S Infusion device and an adhesive sheet material and a release liner
US6926694B2 (en) * 2003-05-09 2005-08-09 Medsolve Technologies, Llc Apparatus and method for delivery of therapeutic and/or diagnostic agents
US7431713B2 (en) 2003-06-18 2008-10-07 Command Medical Products, Inc. Infusion device with safety guard
US7699808B2 (en) 2003-11-10 2010-04-20 Smiths Medical Asd, Inc. Subcutaneous infusion device and method
US7309326B2 (en) 2003-11-18 2007-12-18 Icu Medical, Inc. Infusion set
US20060173413A1 (en) 2004-12-21 2006-08-03 Taiject Medical Device Co., Ltd. Intravenous catheter insertion device with retractable needle

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5451210A (en) 1991-04-29 1995-09-19 Lifequest Medical, Inc. System and method for rapid vascular drug delivery
US5545143A (en) 1993-01-21 1996-08-13 T. S. I. Medical Device for subcutaneous medication delivery
WO1996032981A1 (en) 1995-04-17 1996-10-24 Med Design Corporation Safety stylet for intravenous catheter insertion
US5817058A (en) 1996-12-23 1998-10-06 Shaw; Thomas J. Retractable catheter introducer structure
US6620136B1 (en) 1999-02-18 2003-09-16 Medsafe Technologies, Llc Retractable I-V catheter placement device
WO2002081012A2 (de) 2001-04-06 2002-10-17 Disetronic Licensing Ag Infusionsset

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9192717B2 (en) 2003-11-10 2015-11-24 Smiths Medical Asd, Inc. Subcutaneous infusion device and device for insertion of a cannula of an infusion device and method
EP2596821A1 (en) * 2004-06-16 2013-05-29 Smiths Medical ASD, Inc. Device and method for insertion of a cannula of an infusion device
US8617113B2 (en) 2005-09-15 2013-12-31 Roche Diagnostics International Ag Insertion head with a handle
WO2007031125A1 (de) * 2005-09-15 2007-03-22 F. Hoffmann-La Roche Ag Insertionskopf mit nadelschutz im griff
US7896844B2 (en) 2005-09-15 2011-03-01 Roche Diagnostics International Ag Insertion head with a handle
US8262618B2 (en) 2005-09-15 2012-09-11 Roche Diagnostics International Ag System consisting of an insertion head and an inserter
JP2009507583A (ja) * 2005-09-15 2009-02-26 エフ．ホフマン−ラ ロシュ アーゲー ハンドル内に針保護装置を備えた挿入ヘッド
US8535269B2 (en) 2005-09-15 2013-09-17 Roche Diagnostics International Ag Insertion head with a needle protection in its handle
EP1764122A1 (de) * 2005-09-15 2007-03-21 F.Hoffmann-La Roche Ag Insertionskopf mit Nadelschutz im Griff
JP2010501281A (ja) * 2006-08-23 2010-01-21 メドトロニック ミニメド インコーポレイテッド 針挿入器を備えた注入媒体送達システム、デバイス、および方法、ならびに針挿入器デバイスおよび方法
US8628500B2 (en) 2007-06-25 2014-01-14 Roche Diagnostics Operations Inc. Protector apparatus
US9808574B2 (en) 2007-06-25 2017-11-07 Roche Diabetes Care, Inc. Insertion device
EP2613843B1 (en) 2010-09-10 2021-01-27 Mölnlycke Health Care AB Fixation device
US9744294B2 (en) 2012-03-22 2017-08-29 Terumo Kabushiki Kaisha Puncture device and chemical liquid supplying device
USD709767S1 (en) 2013-03-14 2014-07-29 Becton, Dickinson And Company Package portion for a medical product
US9943641B2 (en) 2013-03-14 2018-04-17 Becton, Dickinson And Company Package for medical product
US10589017B2 (en) 2013-03-14 2020-03-17 Becton, Dickinson And Company Package for medical product
US11229753B2 (en) 2016-04-29 2022-01-25 Smiths Medical Asd, Inc. Subcutaneous insertion systems, devices and related methods
US11998727B2 (en) 2016-04-29 2024-06-04 Smiths Medical Asd, Inc. Subcutaneous insertion systems; devices and related methods

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CA2544303A1 (en) 2005-05-26
JP4685024B2 (ja) 2011-05-18
EP2380620A3 (en) 2012-04-04
EP2383011A2 (en) 2011-11-02
US20050101912A1 (en) 2005-05-12
EP1691877A1 (en) 2006-08-23
EP2380620A2 (en) 2011-10-26
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US7699807B2 (en) 2010-04-20
CA2544303C (en) 2013-06-11
EP1691877B1 (en) 2013-12-18

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