WO2005044185A2 - Compositions de regulation de champ electromagnetique - Google Patents

Compositions de regulation de champ electromagnetique Download PDF

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Publication number
WO2005044185A2
WO2005044185A2 PCT/US2004/034735 US2004034735W WO2005044185A2 WO 2005044185 A2 WO2005044185 A2 WO 2005044185A2 US 2004034735 W US2004034735 W US 2004034735W WO 2005044185 A2 WO2005044185 A2 WO 2005044185A2
Authority
WO
WIPO (PCT)
Prior art keywords
composition
skin
percent
mineral
component
Prior art date
Application number
PCT/US2004/034735
Other languages
English (en)
Other versions
WO2005044185A3 (fr
Inventor
George Cioca
Vasile Ionita-Manzatu
Liliana George
Paolo Giacomoni
Harvey Gedeon
Andrew J. Bevacqua
Glen Rein
Abdul Manirazman
Original Assignee
Color Access, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Color Access, Inc. filed Critical Color Access, Inc.
Priority to AU2004287406A priority Critical patent/AU2004287406A1/en
Priority to CA002544343A priority patent/CA2544343A1/fr
Priority to JP2006538095A priority patent/JP2007509938A/ja
Priority to EP04795843A priority patent/EP1682082A4/fr
Publication of WO2005044185A2 publication Critical patent/WO2005044185A2/fr
Publication of WO2005044185A3 publication Critical patent/WO2005044185A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/47—Magnetic materials; Paramagnetic compounds

Definitions

  • the invention relates to topically applied electromagnetic field shielding cosmetic or pharmaceutical compositions. More specifically, the invention relates to such compositions containing a magnetic component and an ionic component capable of dampening the affect of an electromagnetic field on the skin.
  • microwaves in the range of frequencies of cellular phones have been related to increased cliromosomal aberrations in cultured human lymphocytes, as well as an increased release of histamine from mast cells.
  • Exposure to VLF and ELF electromagnetic waves is being recognized as a possible cause of mild skin disorders.
  • the reaction on the skin to EMF exposure can be seen in, for example, rosacea- like symptoms including itching, warm sensations, pain, erythema, papules, and pustules.
  • G., et al. "Long-term Effects on Symptoms by Reducing Electric Fields From visual Display Units", Scand J Work Environ Health, vol. 25, no. 5, pp.
  • 6,001,282 describes an electromagnetic shield for use on a cell phone, microwave oven, computer, computer monitor, television set, radio, and a variety of other electronic devices.
  • the shield comprises granular tourmaline distributed in a porous carier affixed to the device which produces negative ions (an opposing field) to combat electromagnetic radiation.
  • the present invention achieves these goals and meets the need for protection against electromagnetic radiation on facial skin in a manner that is consistent with the normal daily use of foundation or other similar skin care products.
  • the present invention relates to a cosmetic or pharmaceutical composition for topical application to the skin which comprises a non-magnetic cationic component and a mineral enriched compound and a single domain magnetic component.
  • the amounts of the mineral compound, the cationic component and the magnetic component are such that in combination, they shield the skin against an ambient electromagnetic field (EMF) by providing at least 80 percent dampening of the intensity of the emitted EMF. Therefore, the single domain particles of the magnetic component have E-M wave dampening properties when combined with the cationic component and the mineral compound, and the three components are present in the form of a cosmetic or pharmaceutical composition. By resonating with ambient E-M waves, these two components dampen variable E-M fields and provide protection against potential physiological nuisances on the skin surface.
  • EMF ambient electromagnetic field
  • the mineral enriched compound and the magnetic component containing single domain particles are both present in an E-M wave dampening effective amount.
  • the cationic component comprises cations derived from alkali- or alkali earth metal ions, or zwitterions like amino-acids in the continuous phase of an oil in water emulsion.
  • the cationic component in combination with the mineral enriched compound and the magnetic component provides a surprising effect in dampening or shielding EMF when topically applied to the skin.
  • the present invention also includes methods related to the use of the present compositions, and particularly, the method of dampening the effect of ambient E-M fields on skin surface with a composition comprising 0.01 to 25.0 percent magnetite, 0.1 to 20.0 percent malachite and about 0.001 to 20.0 percent sodium chloride.
  • the present invention is a cosmetic or pharmaceutical composition for protection against ambient E-M waves.
  • the compositions comprise optimal amounts of ionic and magnetic components which can achieve a dampening in the intensity of the incoming emitted E-M field from the surrounding environment.
  • the presence of the magnetic and ionic components is believed, while not wishing to be bound to any particular theory, to resonate with the emitted E-M waves in the surrounding environment, and thus, create a dampening effect of the oscillating E-M fields.
  • compositions of the present invention provide protection for the skin against the physiological nuisances that may be associated with the emission of E-M waves from a variety of electronic devices.
  • the compositions contain optimal amounts of the mineral enriched magnetic component in combination with the cationic component to provide at least about 80 percent dampening of the intensity of the E-M field subjected to the skin.
  • the cationic component is present in an amount of about 0.001 to about 20.0 percent.
  • the combined ionic and magnetic components of the present invention can be used in any type of aqueous system or emulsion system such as, for example, oil in water emulsions, water in oil emulsions, triple emulsions, or other multi-phase emulsion systems.
  • the cationic component can be any known type of cation.
  • useful cations in the cationic component of the present invention include but are not limited to cations derived from sodium chloride and other salts, zwitterions such as amino acids, alkali-metal ions, alkali-earth ions.
  • the cation is present in the continous phase of an emulsion, and more preferably, the emulsion is an oil-in- water emulsion. More preferably, the ionic component is a cation derived from sodium chloride.
  • the magnetic component of the present invention comprises single domain magnetic particles in combination with a mineral type material. The single domain magnet particles are present in an amount of about 0.01 to about 25.0 percent.
  • a single domain magnet refers to a solid in which all the molecules are isotropically oriented. Generally, there exists within a given solid, a zone in which the molecules are isotropically oriented (i.e. in the same direction) and this can give origin to a magnetic field. Essentially, the creation of a single domain magnet/ferromagnet is not a property of an element, per se, but rather, is determined by the arrangement of electrons, allowing each element to behave like a little magnet, hi some substances, individual magnetic moments behave cooperatively so that individual little magnets align themselves in the same direction. These substances strongly interact with a magnetic field because each domain rotates to align itself with the magnetic field and are named ferromagnetics after iron, the most magnetic material.
  • Examples of other magnetic metals include but are not limited to, cobalt, nickel, samarium, dysprosium, and gadolinium; and examples of magnetic metal alloys, include but are not limited to, non-ferro magnetic metal alloys containing copper, manganese, aluminum (e.g., Cu - 65%, Mn - 25%, and Al - 10%;), and ferromagnetic materials which are known to one of ordinary skill in the art.
  • the process for making a ferromagnet is known to one of ordinary skill in the art and can be made by magnetizing a ferromagnetic material .
  • the mineral component as used in the present invention and herein is in combination with the ferrous based magnetic component of the present invention and includes, but is not limited to, SP ceramics, SPT ceramics, C ceramic, colloidal gold, fuchsite (a deep green variety of muscovite, "Brazilian Jade") or granatite (malachite or staurolite), a mineral of a brown to black color occurring in prismatic crystals.
  • the mineral component can also be ferrous-based and this term as used in the present specification means a mineral that may contain iron but not as a major component. Thus it is present in the mineral at comparable levels with other metals in the mineral or less than the amounts of at least one of the other metals.
  • the mineral component of the present invention is granatite, a silicate of aluminum, magnesium, and iron, as the sole single domain magnet.
  • the particle size of the mineral component is less than 50 microns.
  • the fuchsite (potassium aluminum silicate) is less than 45 microns.
  • the mineral component can also be a combination of different ceramics such as in a composite form. An example of a composite of different ceramics is in a material available under the word mark Zeropa (Zeropa S.R.L. Corp., Italy). More preferably, the mineral component comprises malachite.
  • the mineral-enriched compound is present in the compositions of the present invention in an amount of about 0.001 to 20.0 percent.
  • the composition of the present invention is an oil-in-water emulsion.
  • the oil-in-water emulsion contains optimal amounts of ionic and magnetic components for protection against environmental E-M waves which increases proportionally with an increase in the concentration of the ingredients.
  • the compositions contain about 0.001 to 20.0 percent of the magnetic component, about 0.05 to 20.0 percent of the mineral-enriched compound and about 0.001 to 20.0 percent of the cationic component.
  • compositions can also contain sunscreens for protection outdoors against both E-M radiation and ultraviolet radiation.
  • Good protection e.g., greater than 80 percent dampening of the intensity of the field of the incoming electromagetic radiation, in at least a 30 percent aqueous suspension is achieved with granatite, a magnetic component and sodium cations from a NaCl solution.
  • a phosphate buffer solution can be used to provide cations.
  • the granatite is present in an amount of about 0.1 to about 5.0 percent, and the sodium chloride of the cationic component is present in an amount of about 0.01 to 2.0 percent.
  • the present invention also includes a method of shielding a skin surface against E-M waves in the surrounding environment.
  • Other methods involving magnetic particles are known, such as for example, U.S. Patent Nos. 6,033,655, 5,358,659, and 4,046,591. However, in each of these, the magnetic particles interact with a controlled and discretely directed magnetic field. It has not heretofore been known to incorporate single domain magnetic particles in combination with a nonmagnetic ionic component randomly in a cosmetic or pharmaceutical composition.
  • the combination of these two components randomly in a composition has not been known to provide shielding protection against E-M waves when topically applied to the skin by reducing exposure of the E-M field on the skin.
  • the reduction in exposure is between 50 to 90 percent.
  • the benefit of the combination of the cationic and magnetic components can be obtained in any type of topically applied composition such as especially, makeup composition, for example, foundations, eyeshadows, blushes, powders, lipsticks and lipglosses.
  • the compositions of the present invention are used in a foundation.
  • the benefit of the present invention is obtained in a topically applied eye gel, pressed powder, cream or lotion composition, (e.g., moisturizing and other types of treatment products) wherein the product is applied to the skin for a therapeutic purpose, but also has the added advantage of protecting the skin from E-M waves in the surrounding environment.
  • the topical product may be applied solely for the purpose of protecting the skin.
  • the compositions of the present invention also include a compatible carrier.
  • compatible carrier in the present specification and claims is meant any cosmetically acceptable carrier which is compatible with the ionic and magnetic components of the present invention.
  • the carrier may contain one or more oil components.
  • the oil component may be any pharmaceutically or cosmetically acceptable material which is substantially insoluble in water. These materials can be found for example in the CTFA International Dictionary of Cosmetic Ingredients as well as the U.S. Pharmacopoeia or other equivalent sources.
  • Suitable oil components include, but are not limited to, natural oils, such as coconut oil; hydrocarbons, such as mineral oil and hydrogenated polyisobutene; fatty alcohols, such as octyldodecanol; esters, such as C12-15 alkyl benzoate; diesters, such as propylene glycol dipelargonate; triesters, such as glyceryl trioctanoate; sterol derivatives, such as lanolin; animal waxes, such as beeswax; plant waxes, such as carnauba; mineral waxes, such as ozokerite; petroleum waxes, such as paraffin wax; synthetic waxes, such as polyethylene; and mixtures thereof.
  • natural oils such as coconut oil
  • hydrocarbons such as mineral oil and hydrogenated polyisobutene
  • fatty alcohols such as octyldodecanol
  • esters such as C12-15 alkyl benzoate
  • diesters such as propy
  • Suitable oil components may also be silicones.
  • the silicone oil can be volatile or semi-volatile, or any combination thereof.
  • Suitable volatile oils include cyclic and linear silicones, such as hexamethylcyclotrisiloxane, octamethylcyclotetrasiloxane, and decamethylcyclopentasiloxane or volatile linear dimethylpolysiloxanes; or mixtures thereof.
  • volatile silicones include, but are not limited to, cyclomethicone; polymeric silicones such as dimethicone; alkylated derivatives of polymeric silicones, such as cetyl dimethicone and lauryl trimethicone; hydroxylated derivatives of polymeric silicones, such as dimethiconol; and mixtures thereof.
  • the carrier comprises, in the composition as a whole, preferably silicone oil which is present in an amount of at least about 0.5 to about 60 percent by weight.
  • the compatible carrier is one that enhances the soft powdery feel of the composition.
  • a particularly preferred carrier is a low volatile silicone oil.
  • the composition of the present invention may include one or more film-forming agents.
  • a film-former can also improve the wear of the composition, and can confer transfer-resistance to the protective product.
  • useful film-forming agents include natural waxes, polymers such as polyethylene polymers and copolymers of PVP, dimethicone gum, and resins, such as shellac, polyterpenes, and various silicone resins.
  • a particularly preferred film-former is trimethylsiloxysilicate, used in an amount of from about 0.1 to about 20 percent by weight of the total composition.
  • the composition is a lipstick comprising the mineral, cationic and magnetic components in which case, it may also be desirable to incorporate one or more waxes in the composition.
  • wax will be understood to encompass not only waxes in the traditional sense, i.e., those plant, animal or mineral waxes containing primarily esters of higher fatty acids and alcohols, free higher acids and alcohols, and saturated hydrocarbons, but also synthetic resinous products having a wax-like, i.e., hard, brittle, relatively non-greasy texture at room temperature, such as silicone waxes.
  • suitable waxes include, but are not limited to, carnauba wax, candelilla wax, beeswax, microcrystalline wax, polyethylene, japan wax, synthetic wax, shellac wax, spermaceti, lanolin wax, ozokerite, bran wax, ceresin wax, bayberry wax, paraffin, rice wax, mink wax, montan wax, ouricoury wax, jojoba wax, and the like.
  • Additional preferred components of the cosmetic compositions of the invention include one or more pigments. Any cosmetically acceptable pigment, either organic, inorganic, or combinations thereof, can be used in the makeup compositions of the invention. The invention is further illustrated by the following non-limiting example.
  • Raw materials are suspended in water and layered between 2 glass coverslips.
  • the coverslips are situated between a source of an E-M field and an electrometer.
  • the reading of the electrometer when the glass coverslips contain a suspension or formula or when they are blanks permits the measurement of the dampening of the E-M field to be determined and the results are reported as percent protection.
  • Individuals are exposed for 15 minutes to a source of E-M field without cosmetic or with the formulas of the present invention topically applied to the facial skin in an amount of about 2 to 5 mg/cm2. After exposure, the electrical properties of the skin are measured using a gas discharge visualization camera which captures and analyzes photons generated from a corona discharge at the surface of the skin.
  • E-M field exposure to the skin surface is shielded in the range of about 50 to 90 percent.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nanotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

On applique localement une composition d'émulsion pharmaceutique ou cosmétique sur la peau pour la protéger des dommages induits par un champ électromagnétique généré par les appareils utilisés quotidiennement, tels que les téléviseurs, les ordinateurs et les téléphones cellulaires. Ces compositions contiennent des quantités efficaces pour amortir les ondes électromagnétiques ambiantes d'au moins un aimant monodomaine en tant que composant magnétique unique et un composant ionique non magnétique. Le composant magnétique unique fonctionne particulièrement bien dans la composition de l'invention lorsqu'il comprend de la granatite et lorsque la composition est une émulsion de type aqueux.
PCT/US2004/034735 2003-10-31 2004-10-21 Compositions de regulation de champ electromagnetique WO2005044185A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2004287406A AU2004287406A1 (en) 2003-10-31 2004-10-21 Electromagnetic field regulating compositions
CA002544343A CA2544343A1 (fr) 2003-10-31 2004-10-21 Compositions de regulation de champ electromagnetique
JP2006538095A JP2007509938A (ja) 2003-10-31 2004-10-21 電磁場抑制組成物
EP04795843A EP1682082A4 (fr) 2003-10-31 2004-10-21 Compositions de regulation de champ electromagnetique

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51643903P 2003-10-31 2003-10-31
US60/516,439 2003-10-31

Publications (2)

Publication Number Publication Date
WO2005044185A2 true WO2005044185A2 (fr) 2005-05-19
WO2005044185A3 WO2005044185A3 (fr) 2005-09-15

Family

ID=34572884

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/034735 WO2005044185A2 (fr) 2003-10-31 2004-10-21 Compositions de regulation de champ electromagnetique

Country Status (6)

Country Link
EP (1) EP1682082A4 (fr)
JP (1) JP2007509938A (fr)
KR (1) KR100798592B1 (fr)
AU (1) AU2004287406A1 (fr)
CA (1) CA2544343A1 (fr)
WO (1) WO2005044185A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2890857A1 (fr) * 2005-09-22 2007-03-23 Bulgari Parfums Sa Composition a base de concentres mineraux derives de pierres precieuses.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT335617B (de) * 1974-04-23 1977-03-25 Rene Laguerre Verfahren, produkt und gerat zur reinigung der epidermis
JPH072615B2 (ja) * 1986-02-25 1995-01-18 住友セメント株式会社 化粧料
DE4325071C2 (de) * 1993-07-19 1995-08-10 Lancaster Group Ag Präparat zur Durchblutungsförderung
DE19715478A1 (de) * 1997-04-10 1998-10-15 Lancaster Group Gmbh Kosmetisches und dermatologisches Mittel auf Basis von hartmagnetischen Teilchen
US6592882B2 (en) 1999-05-26 2003-07-15 Color Access, Inc. Cosmetic compositions containing fluorescent minerals
CN1207003C (zh) * 2002-01-08 2005-06-22 于宝山 适用于人体保健的矿物集晶袋

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of EP1682082A4 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2890857A1 (fr) * 2005-09-22 2007-03-23 Bulgari Parfums Sa Composition a base de concentres mineraux derives de pierres precieuses.
WO2007034088A2 (fr) * 2005-09-22 2007-03-29 Bulgari Parfums Sa Composition a base de concentres mineraux derives de pierres precieuses

Also Published As

Publication number Publication date
KR100798592B1 (ko) 2008-01-28
EP1682082A4 (fr) 2009-07-08
AU2004287406A1 (en) 2005-05-19
KR20060082083A (ko) 2006-07-14
JP2007509938A (ja) 2007-04-19
EP1682082A2 (fr) 2006-07-26
WO2005044185A3 (fr) 2005-09-15
CA2544343A1 (fr) 2005-05-19

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