WO2004089248A2 - Stent pour anastomose chez un mammifere; methode et systeme d'implantation - Google Patents

Stent pour anastomose chez un mammifere; methode et systeme d'implantation Download PDF

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Publication number
WO2004089248A2
WO2004089248A2 PCT/IL2004/000293 IL2004000293W WO2004089248A2 WO 2004089248 A2 WO2004089248 A2 WO 2004089248A2 IL 2004000293 W IL2004000293 W IL 2004000293W WO 2004089248 A2 WO2004089248 A2 WO 2004089248A2
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WO
WIPO (PCT)
Prior art keywords
sleeve
cover
stent
edge
lumen
Prior art date
Application number
PCT/IL2004/000293
Other languages
English (en)
Other versions
WO2004089248A3 (fr
Inventor
Nachum Erlich
Jacob Gilan
Original Assignee
Giler Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giler Ltd. filed Critical Giler Ltd.
Publication of WO2004089248A2 publication Critical patent/WO2004089248A2/fr
Publication of WO2004089248A3 publication Critical patent/WO2004089248A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064—Surgical staples, i.e. penetrating the tissue
    • A61B17/0643—Surgical staples, i.e. penetrating the tissue with separate closing member, e.g. for interlocking with staple
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A61B17/1114—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis of the digestive tract, e.g. bowels or oesophagus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/0023—Surgical instruments, devices or methods, e.g. tourniquets disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064—Surgical staples, i.e. penetrating the tissue
    • A61B2017/0641—Surgical staples, i.e. penetrating the tissue having at least three legs as part of one single body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A61B2017/1107—Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis for blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers

Definitions

  • the present invention relates generally to the field of intraluminal devices for use in bodily passageways such as blood vessels, the intestines, the esophageal tract, and the urinary tract. More specifically, the present invention relates to a novel stent for providing structural support and reinforcement for a bodily lumen and to a system and method for implanting said stent into the body.
  • stents vascular grafts, and other stents are known in the art for the repair, support, or reinforcement of bodily vessels or other passageways.
  • U.S. Patent No. 6,355,057 to De Marcus et al. entitled, "Staggered Endoluminal Stent”
  • U.S. Patent No. 5,643,339 to Kavteladze et al. entitled, "Stent for Sustaining a Blood-Vessel or Hollow Organ Lumen”
  • U.S. 5,141,516 and U.S. 5,464,415 to Detweiler relates to a dissolvable anastomosis stent and to a method for using the same.
  • the stent is comprised of biocompatible, nontoxic material which completely dissolves mammalian body fluids. All of the aforementioned patents are herein incorporated by reference in their entireties.
  • Biofragmentable anastomosis rings (referred to as BAR or Valtrac) developed by David & Geek, American Cyanamid Company, Danbury, Conn. USA are used for intestinal anastomosis in recent years because they are simple, fast and safe to operate and capable of being fragmented and to pass out of the body in two to three weeks.
  • the BAR functions by holding two vessel stumps in contact with one another after securing each of the vessel stumps to the BAR with a purse-string suture and snapping the two BAR pieces together.
  • the BAR anastomosis procedure requires that purse-string sutures be in and remain in the vessel stumps to attach the vessel stumps to the BAR after the surgical procedure has been completed. These sutures may remain in the vessel tissue for several days to several weeks and their presence increases the risk of infection or leakage and edema. Moreover, it is necessary to dilate the inner lumen in order to properly implant the BAR pieces. Furthermore, the BAR anastomosis is only suitable for usage in the intestine.
  • the inventor of the present invention has developed a novel system for implanting a stent into a body lumen that resolves the problems that are prevalent in the art.
  • the present invention relates to a stent for surgical mammalian vessel anastomosis comprising an inner tubular sleeve having a proximal end and a distal end, and a substantially tubular cover adapted for being closed over said inner tubular sleeve after two severed body lumen ends have been drawn over said proximal and distal ends of said sleeve (one end being drawn over the proximal end, and the other being drawn o ⁇ er the distal end), such that the body lumen ends are fixed between the tubular sleeve, and the cover.
  • the stent is comprised of a biocompatible, non-toxic material.
  • the inner tubular sleeve is formed from a biodegradable material
  • the cover is formed from a bio-absorbable material.
  • the proximal end of the sleeve comprises at least one circular protrusion on the outer surface thereof.
  • the circular protrusion has a first edge and a second edge, said first edge configured at a substantially ninety degree angle with respect to the outer surface of the sleeve, and the second edge configured at an obtuse angle with respect to the outer surface of the sleeve.
  • the proximal end of said sleeve comprises two circular protrusions.
  • the distal end of the sleeve comprises at least one circular protrusion on the outer surface thereof.
  • the circular protrusion has a first edge and a second edge, said first edge configured at a substantially ninety degree angle with respect to the outer surface of the sleeve, and the second edge configured at an obtuse angle with respect to the outer surface of the sleeve.
  • the distal end of said sleeve comprises two circular protrusions.
  • the cover comprises an upper arc-shaped section and a lower arc-shaped section.
  • each of said upper arc shaped sections comprise two longitudinal edges, and opposite longitudinal edges of the upper section and the lower section are adapted for being interlocked with one another.
  • the interlocking may be accomplished through any suitable means l ⁇ iown in the art, such as a pin/groove mechanism.
  • locking is one-way, such that the two sections cannot be easily taken apart from one another.
  • a specialized gripping device is used to interlock the two sections of the cover together.
  • the cover further comprises a plurality of pointed pins located on the inner surface thereof.
  • the stent of the present invention is useful for any bodily lumen, including, with the intestinal lumen, the blood vessels, the urinary tract lumen, and the esophageal tract lumen.
  • the stent may be designed and adapted through ways known to those skilled in the art, so as to fit any body lumen.
  • the present invention relates to a system for performing surgical mammalian vessel anastomosis, comprising;
  • a stent comprising an inner tubular sleeve having a proximal end and a distal end, and a substantially tubular cover adapted for being closed over the inner tubular sleeve after two one severed body lumen ends have been drawn over said proximal and distal ends of said sleeve, such that said body lumen ends are is fixed in between the tubular sleeve and the cover, wherein the stent is formed from a biocompatible material, and; (b) means for applying a compressive force to said cover for causing closing of said cover over said inner tubular sleeve.
  • the stent is also useful in cases where only one luminal end is drawn over one end of the sleeve (in this case, the lumen may be drawn only over a portion of the sleeve, or alternatively, over the entire sleeve), or in other situations as are known in the art.
  • the stent may be adapted in accordance to the characteristics of lumen involved.
  • the inner tubular sleeve may be bifurcated (branched), and, in a corresponding manner, the cover will be adapted for being closed over the bifurcated sleeve.
  • the construction of the stent components may be adapted in accordance with specific considerations involved in the surgical procedure.
  • the inner tubular sleeve is formed from a biodegradable material.
  • the cover is formed from a bio-absorbable material.
  • acceptable materials and acceptable means for the formation of the stent reference is made to U.S. Patent 4,787,900 to Yannas, entitled, “Process for Forming Multilayer Bioreplaceable Blood Vessel Prosthesis” and to U.S. Patent 4,902,289 to Yannas, entitled, “Multilayer Bioreplaceable Blood Vessel Prosthesis” (both patents are herein incorporated by reference).
  • the inner tubular sleeve of the present invention will be designed so as to degrade in the body over a short time span (for example, 21 days), whereas the cover will remain intact for a longer period of time, until healthy new tissue has proliferated around said cover.
  • Each of said tubular sleeve and said cover may be formed from a single, or more preferably, multiple layers of suitable biocompatible material(s).
  • suitable antibiotics or other drugs may be incorporated into the stent so as to protect against side effects of implantation of the stent, and to promote acceptance of the stent by the body.
  • barium sulfate (preferably 10%) is incorporated into the stent.
  • the proximal end of said sleeve comprises at least one circular protrusion on the outer surface thereof.
  • the circular protrusion has a first edge and a second edge, the first edge which is configured at a substantially ninety degree angle with respect to the outer surface of the sleeve, and the second edge which is configured at an obtuse angle with respect to the outer surface of the sleeve.
  • the proximal end of said sleeve comprises two circular protrusions, though it is appreciated that any number of protrusions may be present.
  • the protrusions serve to ensure that once drawn over the proximal end of the tubular sleeve, the body lumen stay in place on the sleeve.
  • the distal end of said sleeve comprises at least one circular protrusion on the outer surface thereof.
  • the circular protrusion has a first edge and a second edge, said first edge being configured at a substantially ninety degree angle with respect to the outer surface of the sleeve, and said second edge being configured at an obtuse angle with respect to the outer surface of the sleeve.
  • the distal end of said sleeve comprises two circular protrusions, though it is appreciated that any number of protrusions may be present.
  • the cover comprises an upper arc-shaped section and a lower arc-shaped section, and the opposite longitudinal edges of said upper section and said lower section are adapted for being interlocked with one another.
  • the cover is formed by two semi-circular components that interlock with one another in order to form a substantially tubular- shaped cover that encircles the inner sleeve, after the body lumen has been drawn over the sleeve. It will be appreciated that the cover can be properly placed by the surgeon in a very fast, efficient and convenient manner, thus obviating the need for timely and complicated suturing.
  • the cover allows of the secure, and reliable placement of the stent in a straightforward manner that was heretofore unknown in the art.
  • the means for compressing and closing the cover over the sleeve comprises a gripping device for gripping the upper section and lower section of the cover and for causing the opposite longitudinal edges of the upper section and lower sections to become interlocked with one another over the sleeve.
  • the gripping device preferably comprises an upper gripper and a lower gripper, for holding the upper and lower sections, respectively, of the stent, and for bringing the two sections together, and interlocking their longitudinal edges over the inner sleeve, during a surgical procedure. It is appreciated that the gripping device is easy for the surgeon to use, and allows for the cover to be securely placed on the sleeve and the body lumen in a quick and efficient manner.
  • the gripping device is adapted for allowing the surgeon to deteimine, depending on the diameter of the stent, the amount of compressive force that is applied.
  • the force should be just sufficient enough to interlock the two sections of the cover with one another. This is important since it assures that no extra strain is applied to the body lumen, and that blood can flow through them easily. It is appreciated, however, that in some preferred embodiments, the surgeon may carry out closing of the cover using his hands, without the use of a gripping device.
  • the gripping device greatly facilitates closing of the cover, though it is not absolutely necessary.
  • the stent of the present invention provides internal support, as well as external support for the body lumen that is being anastomed.
  • the cover further comprises a plurality of pins located on the inner surface thereof.
  • the pins serve to facilitate holding of the tissue in place in the prosthesis.
  • the pins are adapted for piercing the tissue so as to provide additional support though it is appreciated that they do not put undo pressure on the tissue so as to result in the formation of holes or tears.
  • each of the upper and lower sections of the cover comprises four pins, though it is appreciated that other numbers of pins may be present as well.
  • the pins are about 0.4 millimeters in length, though the size may vary. It is appreciated that the pins pierce the body lumen, but they do not penetrate through the lumen.
  • the system of the present invention is useful for surgical procedures conducted in the intestinal lumen, the blood vessels, the urinary tract lumen, and the esophageal tract lumen, though it is appreciated that the system could be adapted for use with virtually all passageways of the body.
  • the present invention also relates to a method for implanting a stent between two severed ends of a body lumen, comprising; (a) providing a stent comprising an inner tubular sleeve having a proximal end and a distal end, and a substantially tubular cover adapted for being closed over the inner tubular sleeve after two severed body lumen ends have been drawn over the proximal and distal ends of said sleeve (one lumen being drawn over the proximal end and the other lumen being drawn over the distal end), such that said body lumen ends are fixed in between the tubular sleeve and the cover, wherein the stent is formed from a biocompatible material, and wherein the cover comprises an upper arc- shaped section and a lower arc-shaped section having longitudinal edges that are adapted for being interlocked with one another;
  • the inner tubular sleeve is formed from a biodegradable material.
  • the cover is formed from a bio-absorbable material.
  • the proximal end of said sleeve comprises at least one circular protrusion on the outer surface thereof.
  • the circular protrusion has a first edge and a second edge, said first edge configured at a substantially ninety degree angle with respect to the outer surface of the sleeve, and said second edge configured at an obtuse angle with respect to the outer surface of the sleeve.
  • the proximal end of said sleeve comprises two circular protrusions, though it is appreciated that any number of protrusions may be present.
  • the distal end of said sleeve comprises at least one circular protrusion on the outer surface thereof.
  • the circular protrusion has a first edge and a second edge, said first edge configured at a substantially ninety degree angle with respect to the outer surface of the sleeve, and said second edge configured at an obtuse angle with respect to the outer surface of the sleeve.
  • the distal end of said sleeve comprises two circular protrusions, though it is appreciated that any number of protrusions may be present.
  • the cover further comprises a plurality of pins located on the inner surface thereof.
  • the pins serve to facilitate holding of the tissue in place in the prosthesis.
  • the pins are adapted for piercing the tissue so as to provide additional support though they do not put too much pressure on the tissue so as to result in the formation of holes or tears.
  • each of the upper and lower sections of the cover comprises four pins, though it is appreciated that other numbers of pins may be present as well.
  • the gripping device comprises an upper gripper and a lower gripper, for gripping said upper section and said lower section, respectively, of said cover and for causing said opposite longitudinal edges of said upper section and said lower section to become interlocked with one another.
  • the method of the present invention is useful for surgical procedures conducted in the intestinal lumen, the blood vessels, the urinary tract lumen, and the esophageal tract lumen, though it is appreciated that the system could be adapted for use with virtually all passageways of the body.
  • Figure 1 is an isometric side view of a preferred embodiment of a stent for use in the system of the present invention.
  • the stent comprises an inner tubular sleeve and a cover having an upper section and a lower section.
  • Figure 2 is a side view of the inner tubular sleeve of the stent of Figure 1.
  • Figure 3 is an isometric side view of the cover of the stent of Figure 1, shown with the upper and lower sections of the cover interlocked with one another.
  • Figure 4a is a side view, taken from the outside, of the upper section of the cover shown in Figure 3.
  • Figure 4b is a cross-sectional view of the upper section illustrated in Figure 4a.
  • Figure 5a is a side view, taken from the outside, of the lower section of the cover shown in Figure 3.
  • Figure 5b is a cross-sectional view of the lower section illustrated in Figure 5 a.
  • Figure 6 is a cross-sectional side view of a section of body lumen fixed in between the inner tubular sleeve and the cover of the stent of Figure 1.
  • Figure 7 is a schematic side view of a mechanical gripping device for closing the cover of the stent of Figure 1 onto the inner tubular sleeve of the stent of Figure 1.
  • the system of the present invention comprises a stent having two main components: an inner tubular sleeve (20) and a cover (30).
  • the inner tubular sleeve (20) is implanted in the interior of two severed body lumen ends whereas the cover is positioned over said body lumen ends.
  • the construction of the stent allows for maximal support of a body lumen.
  • the cover (30) comprises an upper arc-shaped section (15) and a lower arc-shaped section (25).
  • the sleeve (20) is adapted for being implanted on the internal side of a body lumen whereas the cover (30) is adapted for being secured over the sleeve, after two severed body lumens have been drawn onto the outer surface of the sleeve, so as to provide a new conduit between the two severed ends.
  • the tubular sleeve (20) has a proximal end (12) and a distal end (14), each end being adapted for receiving a severed end of body lumen over the outer surface of said sleeve (20).
  • Each protrusion (23a) (23b) (24a) (24b) has a first edge (9) and a second edge (7), said first edge (9) being configured at a substantially 90° angle with respect to the tubular sleeve (20) and said second edge (7) being configured at an obtuse angle with respect to the tubular sleeve (20).
  • Each end of the sleeve (20) preferably comprises two circular protrusions, though it appreciated that any suitable number may be employed.
  • the upper section (15) and the lower section (25) of the cover are adapted for being interlocked with one another so as to form a substantially tubular cover that becomes enclosed over the sleeve during implantation of the stent.
  • the tissue is securely sandwiched between the sleeve (20 and the cover (30).
  • the upper section (15) of the cover comprises a plurality locking pins (17a-h) positioned on the two longitudinal edges of said cover. Each edge preferably comprises four locking pins, though it is appreciated that the cover could be configured with any suitable number of pins.
  • the locking pins (17a-h) are adapted in shape for being inserted into a plurality of grooves (18) (seen in Figure 1 and in Figure 5b) that are located on the longitudinal edges of the lower section (25) of the cover.
  • the pin/groove lock is a one-way lock, which cannot be readily undone, but which requires a specialized device in order to unlock, if it is necessary to take off the cover. It is appreciated however, that various other appropriate locking mechanisms could also be employed for interlocking the upper and lower sections of the cover with one another. In some embodiments, the locking may be adapted for being accomplished manually by the surgeon.
  • a gripping device (to be described in Figure 7) is employed for facilitating the interlocking of the two sections of the cover over the sleeve.
  • the gripping device allows for closing of the cover to be carried out in a fast, efficient, and reliable manner.
  • each of the upper section (15) and lower section (25) of the cover comprises a plurality of pointed pins (13a) (13b) (13c) (13d) that protrude from the inner surface of the cover sections (15) (25) (see Figures 4b and 5b).
  • the pins function to hold the cover in place on the body tissue and the inner sleeve once said cover has been locked over the sleeve by the gripping device.
  • the pins (13) may have any appropriate size, though it is appreciated that are designed so as provide additional support while not putting too much pressure on the tissue held by the stent (so that the tissue will not tear or become weakened due to the pins).
  • the pins are sized so as not to penetrate completely through the tissue, but they are sufficient so as prevent movement of the tissue. In anastomosis of intestinal lumen, the pins will be approximately 0.4mm in length.
  • a section of body tissue (22) is illustrated between the inner tubular sleeve (20) and the cover (30) of the stent, following the positioning of the tissue (22) on the sleeve (20), and subsequent closing of the cover (30) on top of the sleeve (20).
  • the gripping device (32) preferably comprises an upper gripper (36a) and a lower gripper (36b), each having a semi-circular shape, for holding the upper and lower sections, respectively, of the cover.
  • the gripping device (32) is equipped with a mechanism (38) for effecting the upward and downward movement of the upper and lower grippers (36a) (36b).
  • the mechanism (38) includes an upper arm (37a) and a lower arm (37b) to which the grippers are respectively coupled.
  • the two arms (37a) (37b) are each coupled to a main gear (39).
  • Said main gear (39) is in turn operably coupled to an actuating rod (40) that is adapted for moving back and forth along the longitudinal axis of the device.
  • the mechanism (38) is coupled to a locking handle (34) that is adapted for being pulled by the user, for actuating said mechanism.
  • a stopper (35) restricts pulling back of the handle (34) to the necessary amount.
  • the device is also equipped with a tension regulator (44), which regulates the amount of compressive force applied by the upper gripper (36a) and the lower gripper (36b) to the cover.
  • the regulator (44) can be easily set by the surgeon so as to adjust the height of the stopper (35), thereby determining the extent to which the handle (34) can be pulled and the extent to which the grippers (36a) (36b) move. It is appreciated that the gripping device described is adapted for being adjusted for use with stents having varying diameters. In some cases, however, stents constructed in different sizes may be provided, which each size stent having its own disposable gripping device, specifically designed for applying the appropriate amount of pressure for closing the cover over the sleeve of the particular stent.
  • the cover may be adapted for being closed directly by the hands of the surgeon.
  • the stent of the present invention could be readily modified without departing from the scope of the invention as set out in the claims.
  • the material from which the stent is made could be selected so as to provide a stent that has a flexible nature, thereby enabling the surgeon to manipulate the stent easily for proper implantation into the body.
  • the stent diameter could change over the length of the stent.
  • two stents having two different diameters could be used for one surgical procedure, with a conical connector serving to connect the two stents together.
  • the stent may be bent or may have a certain angle, in order to fit particular types of body vasculature.

Abstract

Généralement parlant, la présente invention concerne le domaine des dispositifs endoluminaux destinés à être mis en place dans des conduits corporels tels que vaisseaux sanguins, intestins, oesophage ou tractus urinaire. Plus spécifiquement, cette invention concerne un nouveau stent assurant un support structural et un renfort pour un conduit organique, ainsi qu'un système et une méthode de mise en place dudit stent dans le corps.
PCT/IL2004/000293 2003-04-09 2004-03-31 Stent pour anastomose chez un mammifere; methode et systeme d'implantation WO2004089248A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL155305 2003-04-09
IL15530503A IL155305A0 (en) 2003-04-09 2003-04-09 Stent for use in mammalian anastomosis and method and system for implanting said stent

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Publication Number Publication Date
WO2004089248A2 true WO2004089248A2 (fr) 2004-10-21
WO2004089248A3 WO2004089248A3 (fr) 2004-11-18

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101026933B1 (ko) * 2010-11-08 2011-04-04 주식회사 메타바이오메드 혈관 문합 장치
CN102423273A (zh) * 2011-10-09 2012-04-25 中国人民解放军第三军医大学第三附属医院 输精管支架
EP3182904A4 (fr) * 2014-08-24 2018-07-25 Boiman, Alon Dispositif de suture d'anastomose
CN108903984A (zh) * 2018-07-20 2018-11-30 中国医学科学院阜外医院 夹持式血管连接装置

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US3254650A (en) * 1962-03-19 1966-06-07 Michael B Collito Surgical anastomosis methods and devices
US3620218A (en) * 1963-10-31 1971-11-16 American Cyanamid Co Cylindrical prosthetic devices of polyglycolic acid
WO1994027506A2 (fr) * 1993-05-21 1994-12-08 Biovision Gmbh Entwicklung, Herstellung Und Vertrieb Von Biomaterialien Dispositif d'anastomose
EP0781528A2 (fr) * 1992-02-28 1997-07-02 Shadyside Hospital Dispositif pour relier et fermer des vaisseaux sanguins séparés
DE10015145A1 (de) * 2000-03-29 2001-10-11 Fraunhofer Ges Forschung Verbindungsanordnung für die Gefäßanastomosie und Verfahren für die Gefäßanastomosie
WO2002096299A1 (fr) * 2001-05-31 2002-12-05 Hb Medicals Corporation Dispositif d'anastomose
WO2003007843A2 (fr) * 2001-07-17 2003-01-30 Universite Joseph Fourier Dispositif d'anastomose vasculaire

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3254650A (en) * 1962-03-19 1966-06-07 Michael B Collito Surgical anastomosis methods and devices
US3620218A (en) * 1963-10-31 1971-11-16 American Cyanamid Co Cylindrical prosthetic devices of polyglycolic acid
EP0781528A2 (fr) * 1992-02-28 1997-07-02 Shadyside Hospital Dispositif pour relier et fermer des vaisseaux sanguins séparés
WO1994027506A2 (fr) * 1993-05-21 1994-12-08 Biovision Gmbh Entwicklung, Herstellung Und Vertrieb Von Biomaterialien Dispositif d'anastomose
DE10015145A1 (de) * 2000-03-29 2001-10-11 Fraunhofer Ges Forschung Verbindungsanordnung für die Gefäßanastomosie und Verfahren für die Gefäßanastomosie
WO2002096299A1 (fr) * 2001-05-31 2002-12-05 Hb Medicals Corporation Dispositif d'anastomose
WO2003007843A2 (fr) * 2001-07-17 2003-01-30 Universite Joseph Fourier Dispositif d'anastomose vasculaire

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101026933B1 (ko) * 2010-11-08 2011-04-04 주식회사 메타바이오메드 혈관 문합 장치
CN102423273A (zh) * 2011-10-09 2012-04-25 中国人民解放军第三军医大学第三附属医院 输精管支架
EP3182904A4 (fr) * 2014-08-24 2018-07-25 Boiman, Alon Dispositif de suture d'anastomose
CN108903984A (zh) * 2018-07-20 2018-11-30 中国医学科学院阜外医院 夹持式血管连接装置

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