WO2004084923A1 - 抗ストレス剤 - Google Patents
抗ストレス剤 Download PDFInfo
- Publication number
- WO2004084923A1 WO2004084923A1 PCT/JP2004/003898 JP2004003898W WO2004084923A1 WO 2004084923 A1 WO2004084923 A1 WO 2004084923A1 JP 2004003898 W JP2004003898 W JP 2004003898W WO 2004084923 A1 WO2004084923 A1 WO 2004084923A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- seafood
- fish
- lactobacillus
- lactic acid
- acid bacteria
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
Definitions
- the present invention relates to an anti-stress agent that imparts resistance to seafood against the adverse effects of stress.
- the present invention also relates to an aquaculture method using the same.
- antibiotics drugs such as antibiotics have been widely used.
- antibiotics and other drugs are effective to some extent, but there are safety problems such as residues in animals and environmental pollution, and adverse effects due to the emergence of resistant bacteria. Heading in the direction.
- viable bacteria include photosynthetic bacteria (PSB), mixed microorganisms (trade name “Cycle”: manufactured by Sudo Co., Ltd., trade name “Super Bio”: manufactured by Tomofuji Co., Ltd.), and the like.
- PSB photosynthetic bacteria
- mixed microorganisms trade name “Cycle”: manufactured by Sudo Co., Ltd., trade name “Super Bio”: manufactured by Tomofuji Co., Ltd.
- many of these viable bacteria agents are room temperature storage liquid types, and the viable cell retention rate before use is generally poor.
- An object of the present invention is to provide a preparation for effectively preventing or treating stress in seafood.
- the present inventors have unexpectedly and surprisingly found that a dead cell of lactic acid bacteria or a processed product thereof is not stressed for fish and shellfish. It has been found that it has an excellent effect on the prevention or treatment of the disease.
- the dead cells are used as active ingredients instead of living lactic acid bacteria, the present inventors can easily handle the active ingredients and process management easily when producing anti-stress agents.
- the active ingredient in the formulated product is highly stable during storage and in water I also learned that.
- An anti-stress agent for seafood characterized by containing dead lactic acid bacteria or a processed product thereof
- Lactobacillus Lactobacillus plantarum Lactobacillus acidophilus, Lactobacillus brevis, Lactobacillus casei, Lactobacillus casei, Lactobacillus casei, Lactobacillus casei, Lactobacillus casei, Lactobacillus casei fermentunu, Lactobacillus paracasei, Lactobacillus buchneri, Lactobacillus delbrueckii, Lactobacillus rhamnosus (Lactobacillus rhamnosus octo) thermophi lus, Enterococcus faecalis> Enterococcus faecium, Lactococcus lactis, Lactococcus plantarum (Lact) ococcus pi ant arum) or Bifidobacterium thermophi lum, Bifidobacterium longum Bifidobacterium breve Bifidobacterium breve A
- the ratio of dead lactic acid bacteria or treated product thereof is 0.1 to 50% by mass relative to the total amount, according to any one of (1) to (7) above Anti-stress agent for seafood,
- a method for preventing or treating seafood stress comprising feeding the seafood with the antistress agent for seafood according to any one of (1) to (8) above, (12) Death of lactic acid bacteria
- a method for preventing or treating stress in seafood characterized by feeding the body or processed product thereof to seafood at a rate of 0.0005 to 75 mg per day per kg of seafood;
- a method for suppressing a rise in serum cortisol in seafood comprising using the antistress agent for seafood according to any one of (1) to (8) above,
- lactic acid bacteria any known lactic acid bacteria such as Lactobacillus genus, Streptococcus genus, Enterococcus genus, Lactococcus genus or Bifidobacterium can be used.
- Lactobacillus pi ant arum Lactobacillus acidophilus, Lactobacillus brevis, Lactobacillus brevis, Lactobacillus casei, Lactobacillus casei, Lactobacillus fermentum, Lactobacillus paracasei, Lactobacillus buchneri, Lactobacillus buchneri, Lactobacillus delbruecki i, Lactobacillus delbruecki i, Lactobacillus Streptococcus thermophilus, Enterococcus faecalis, Enterococcus faecium, Lactococcus lactis, Lactococcus lactis (Lactococcus plantarum), Bifidobacterium thermophilum, Bifidobacterium longum, Bifidobacterium breve and the like. Of these various lactobacilli, Lactobacillus plantarum is preferred.
- Lactobacillus plantarum L 1 137 can be mentioned as a representative of the bacteria belonging to Lactobacillus plantarum used in the present invention. This bacteria is an independent administrative agency, National Institute of Advanced Industrial Science and Technology. Deposited at the center under the deposit number FERM BP-08607 (transferred from FE RM P-15317 deposited on November 30, 1995).
- the Lactobacillus plantarum used in the present invention further includes Lactobacillus plantarum. (Lactobacillus pi ant arum) JCM 1 1 4 9 Reference strain and Lactobacillus plantarum L— 0 5 1 (Microbiken No. 1 1 9 1 2) are included. Lactobacillus planum lamb L— 1 3 7 is most preferred.
- the bacterium used in the present invention can be obtained by culturing in a medium such as a natural medium, a synthetic medium, or a semi-synthetic medium.
- a medium containing a nitrogen source and a carbon source is used as the medium.
- Nitrogen sources include, for example, meat extract, peptone, gluten, casein, yeast extract, amino acids, etc.
- carbon sources include, for example, glucose, xylose, flax 1 ⁇ 1s, wild boar, maltose, water Me, soup, starch, bacus, bran, molasses, glycerin, etc. are used.
- ammonium sulfate, potassium phosphate, magnesium chloride, sodium chloride, iron, manganese, molybdenum, and the like can be added as inorganic substances, and various vitamins and the like can be added.
- the culture temperature is about 25 to 40 ° C, preferably about 27 to 35 ° C
- the culture time is about 12 to 48 hours, and aeration and shaking may be performed.
- the pH of the medium is about 3-6, preferably about 4-6.
- the cells may be collected and then killed cells may be prepared, or the cells in the culture solution may be changed to dead cells without separating the cells from the culture solution. Bacteria may be collected.
- Dead cells can be obtained by inactivating the collected live cells or the culture medium containing the live cells, for example, by heating, ultraviolet irradiation, formalin treatment, or the like.
- the heating temperature is usually about 60 to 100 ° C., preferably about 70 to 9.
- the heating means may be a known means using a heater.
- the heating time is usually about 5 to 40 minutes, preferably about 10 to 30 minutes after reaching the desired temperature.
- the treated product of dead cells can be obtained, for example, by freeze-drying or spray-drying dead cells.
- appropriate excipients such as dextrin and cellulose to dead cells, This can also be obtained by freeze drying or spray drying.
- the processed product of dead cells may also be an extract of dead cells.
- the seafood in the present invention is not particularly limited, and may be any of freshwater fish, saltwater fish, and crustaceans, and may be any of cultured fish and ornamental fish.
- freshwater fish include eel, carp, rainbow trout, ayu, tilapia, crucian carp, goldfish (e.g., lunchyu, Japanese gold, comet, vermilion gold, Dutch shigashira, dice, etc.), guppy, apistogramma, and dish.
- Examples of saltwater fish include bluefin tuna, puri, Thailand, coho salmon, horse mackerel, flounder, flounder, blackfish, trough, and amberjack.
- salmon trout and the like can be mentioned as belonging to both freshwater fish and saltwater fish.
- crustaceans include prawns, black taiga, ushebi, kolayebi, and crab.
- the seafood as described above may be any of larvae (including small fish, larvae, fry, and juveniles) and adult fish.
- the anti-stress agent of the present invention may be a killed lactic acid bacterium or a processed product thereof, or a preparation obtained by mixing dead cells or a processed product thereof with an excipient or diluent.
- the blending ratio of dead cells or processed product thereof to the whole preparation is preferably about 0.1 to 95% by mass, more preferably about 0.1 to 50% by mass.
- the dosage form include pellets, tablets, liquids, powders, granules, and pastes. Such preparations can be brought into contact with seafood or given orally.
- Solid excipients or diluents include, for example, fish meal, bone meal, skim milk, cottonseed meal, wheat flour, wheat germ, rice bran, brewer's yeast, cellulose, vitamins (eg / 3-strength rotin, vitamin D 3 , Menadione-sodium hydrogen sulfite, —tocopherol, thiamine—nitrate, riboflavin, pyridoxine—hydrochloride, cyanocobalamin, piotin, inositol, nicotinic acid, calcium pantothenate, folic acid, choline choline, paraaminobenzoic acid or vitamin C Etc.), mineral mixes (eg magnesium sulfate, disodium phosphate, 2-natto phosphate) And so-called feed materials such as potassium potassium, iron citrate, calcium lactate, aluminum hydroxide, sulfite sulfate, copper sulfate, manganese
- liquid excipient or diluent examples include water or a mixture of water and alcohol.
- the antistress agent of the present invention can be easily produced by mixing dead bacteria of Lactobacillus plantum or a processed product thereof with the above-mentioned excipient or diluent. When mixing, it may be heated as desired to obtain a flaky preparation. The preparation of the present invention thus produced may be used as a feed for seafood. When used as feed, the concentration of dead cells in the feed or processed product thereof is preferably more than about 0 ppm and not more than 200 ppm, more preferably from about 0.1 to 200 ppm. is there.
- the feeding amount of the antistress agent for seafood of the present invention is 0.05 to 75 mg per day per kg body weight of the seafood in terms of the above-mentioned dead cells of lactic acid bacteria or processed products thereof. It is preferable that it is 0.05 to 7.5 mg.
- One possible mechanism for the anti-stress effect of the preparation of the present invention on fish and shellfish is to suppress the rise in serum cortisol.
- the neuro-endocrine system first responds to stress and secretes neurotransmitters and hormones.
- Physiological effects of secreted neurotransmitters and hormones can cause physiological changes in the body, which can lead to growth inhibition, reproductive function and decreased resistance to disease.
- the effects of these stresses are the result of the integration of various substances such as neurotransmitters and hormones, but it is said that cortisol plays the leading role (cultured 2001. No. 1 1, 56- 59). Therefore, it is possible to resist the adverse effects of stress as described above by suppressing the rise in cortisol.
- the antistress agent for seafood of the present invention has an action of suppressing the rise of cortisol in seafood, and when administered to seafood, the stress of seafood can be effectively prevented or treated.
- the weight of seafood increases, the growth of seafood increases, The survival rate is improved and the taste quality of seafood (eg, texture, flavor, etc.) is improved.
- strain was inoculated into 6 L of a medium containing 0.001% and 0.05% sucrose fatty acid ester, and cultured at 32 for 24 hours. After culturing, the culture was centrifuged at 5000 rpm for 35 minutes to collect the cells.
- the obtained bacterial cells were well dispersed in physiological saline and centrifuged at 5000 rpm for 35 minutes, and then the supernatant was removed to collect the bacterial cells. After repeating this operation three times, the cells were dispersed in ion-exchanged water, heated at 70 ° C. for 10 minutes, and then freeze-dried to obtain about 7 g of heated dead cells. (Manufacture of pellets from dead cells)
- Brown Fish Meal 65 6 parts by weight, —Starch 3.4 parts by weight, dextrin 3.4 parts by weight, soy lecithin 4.2 parts by weight, sodium menadione hydrogen bisulfate 0.0124 parts by weight, thiamine mononitrate 0.01797 Parts by mass, riboflavin 0.05991 parts by mass, pyridoxine monohydrochloride 0.014 8 parts by mass, cyanobalamine 0.00002 parts by mass, cellulose 0.5986 9 parts by mass, piotin 0.00191 parts by mass, inositol 1.
- vitamin-containing ⁇ liver oil ⁇ fF oil 7 parts by weight, ⁇ Ichirotin 0.0996 parts by weight, vitamin D 3 0.00301 parts by weight, ⁇ -tocopherol 0.111993 parts by weight
- ultrasonic washing machine The mixture was added using Lactobacillus branulam L_137 heated dead cells are added to this to a predetermined concentration, then ⁇ -cell mouthwater is added, and the total amount is adjusted to 100 parts by mass to feed dead cells. It was.
- the addition concentration of the heated dead cells was set to 5 levels of 0, 0.2, 2, 20, and 200 ppm in the dead cell-containing feed, respectively.
- Red sea bream larvae (weight: 0.9 ⁇ 0. lg) were placed in a circulating 30L circular polycarbonate tank, 15 each, and 3 tanks were set for each test feed, and the test feed was taken twice a day in the morning and evening. 5-7% of the body weight was given, the water change rate was 2.4 LZ, and the water temperature was maintained at 20. 0 ° C.
- blood was collected from the tail capillaries. After preparing serum from this blood, the amount of cortisol in the serum was measured by ELISA. The results are shown in Table 2. Table 2
- Lactobacillus plantarum L-1 137 strain (Lactobacillus plantarum L-137) heat-killed cells containing 0.2 ppm or more of the feed group were fed in the test group.
- Cortisol in red sea bream serum was significantly lower than in the control group that received a diet that did not contain dead cells.
- Lactobacillus planon Talam L-137 (Lactobacillus plantarum L-137) was cultured at 32 ° C for 24 hours, and the culture was heat-treated at 80 for 20 minutes. Thereafter, the culture solution was washed and concentrated with a filter concentration device while adding water to obtain a heated dead cell solution. Dextrin was added to the obtained heated dead cell solution and spray-dried to obtain a treated product of dead cells containing 18% of heated dead cells.
- composition of the vitamin mix is shown in Table 3, and the composition of the mineral mix is shown in Table 4.
- the mineral mix and vitamin mix were the same as in Example 2.
- test group is overwhelmingly preferred for the overall evaluation of the texture, flavor, and texture, appearance, and flavor. It has been shown. In particular, regarding the texture, the test group was more elastic and delicious, and the test group had a sense of crispiness and was often rated delicious. Regarding the flavor, the test group was more evaluated as having no odor.
- the anti-stress agent of the present invention can effectively prevent or treat seafood stress.
Abstract
Description
Claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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JP2005504047A JP4813902B2 (ja) | 2003-03-26 | 2004-03-22 | 抗ストレス剤 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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JP2003086419 | 2003-03-26 | ||
JP2003-086419 | 2003-03-26 |
Publications (1)
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WO2004084923A1 true WO2004084923A1 (ja) | 2004-10-07 |
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Family Applications (1)
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PCT/JP2004/003898 WO2004084923A1 (ja) | 2003-03-26 | 2004-03-22 | 抗ストレス剤 |
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WO (1) | WO2004084923A1 (ja) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008018143A1 (fr) * | 2006-08-10 | 2008-02-14 | House Wellness Foods Corporation | Agent hydratant |
CN101278702B (zh) * | 2007-04-05 | 2011-03-23 | 北京大北农科技集团股份有限公司 | 一种新型微生物饲料添加剂及其制备方法 |
CN103262952A (zh) * | 2013-03-14 | 2013-08-28 | 盐城工学院 | 一种异育银鲫抗应激膨化饲料及其生产方法 |
CN106923080A (zh) * | 2017-03-08 | 2017-07-07 | 广东海洋大学 | 一种提高多鳞鱚幼鱼抗运输应激力的饲料添加剂 |
WO2019180263A3 (en) * | 2018-03-22 | 2019-11-28 | Adare Pharmaceuticals Sas | New use of microbiological compositions |
CN110916014A (zh) * | 2019-11-26 | 2020-03-27 | 上海泓宝绿色水产股份有限公司 | 一种内服型抗暑菌 |
JPWO2022065268A1 (ja) * | 2020-09-25 | 2022-03-31 | ||
CN114391493A (zh) * | 2021-12-16 | 2022-04-26 | 佛山市顺德区活宝源生物科技有限公司 | 加州鲈的捕捞方法 |
US11571447B2 (en) | 2017-05-26 | 2023-02-07 | House Wellness Foods Corporation | Composition for preventing, ameliorating or treating metabolic syndrome |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010092817A1 (ja) * | 2009-02-12 | 2010-08-19 | 有限会社アートスクリュー | 締結部材および締結構造 |
WO2011105225A1 (ja) | 2010-02-26 | 2011-09-01 | 有限会社アートスクリュー | 締結部材および締結構造 |
Citations (3)
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JPH09308440A (ja) * | 1996-05-21 | 1997-12-02 | Shimadzu Corp | 水生動物の体質改善剤及び体質改善方法 |
JPH1192390A (ja) * | 1997-09-17 | 1999-04-06 | Natl Fedelation Of Agricult Coop Assoc | ストレス状態改善剤 |
JP2002080364A (ja) * | 2000-09-01 | 2002-03-19 | Takeda Food Products Ltd | 免疫増強組成物 |
-
2004
- 2004-03-22 WO PCT/JP2004/003898 patent/WO2004084923A1/ja active Search and Examination
- 2004-03-22 JP JP2005504047A patent/JP4813902B2/ja not_active Expired - Lifetime
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09308440A (ja) * | 1996-05-21 | 1997-12-02 | Shimadzu Corp | 水生動物の体質改善剤及び体質改善方法 |
JPH1192390A (ja) * | 1997-09-17 | 1999-04-06 | Natl Fedelation Of Agricult Coop Assoc | ストレス状態改善剤 |
JP2002080364A (ja) * | 2000-09-01 | 2002-03-19 | Takeda Food Products Ltd | 免疫増強組成物 |
Non-Patent Citations (1)
Title |
---|
IIDA TAKATSUGU: "Sakana no stress to seitai bogyo kassei", YOSHOKU, vol. 38, no. 11, 2001, pages 57 - 59, XP002982729 * |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008018143A1 (fr) * | 2006-08-10 | 2008-02-14 | House Wellness Foods Corporation | Agent hydratant |
JPWO2008018143A1 (ja) * | 2006-08-10 | 2009-12-24 | ハウスウェルネスフーズ株式会社 | 保湿剤 |
US8114658B2 (en) | 2006-08-10 | 2012-02-14 | House Wellness Foods Corporation | Method of moisturizing skin |
JP5121715B2 (ja) * | 2006-08-10 | 2013-01-16 | ハウスウェルネスフーズ株式会社 | 保湿剤 |
CN101278702B (zh) * | 2007-04-05 | 2011-03-23 | 北京大北农科技集团股份有限公司 | 一种新型微生物饲料添加剂及其制备方法 |
CN103262952A (zh) * | 2013-03-14 | 2013-08-28 | 盐城工学院 | 一种异育银鲫抗应激膨化饲料及其生产方法 |
CN106923080A (zh) * | 2017-03-08 | 2017-07-07 | 广东海洋大学 | 一种提高多鳞鱚幼鱼抗运输应激力的饲料添加剂 |
US11571447B2 (en) | 2017-05-26 | 2023-02-07 | House Wellness Foods Corporation | Composition for preventing, ameliorating or treating metabolic syndrome |
WO2019180263A3 (en) * | 2018-03-22 | 2019-11-28 | Adare Pharmaceuticals Sas | New use of microbiological compositions |
CN110916014A (zh) * | 2019-11-26 | 2020-03-27 | 上海泓宝绿色水产股份有限公司 | 一种内服型抗暑菌 |
JPWO2022065268A1 (ja) * | 2020-09-25 | 2022-03-31 | ||
WO2022065268A1 (ja) * | 2020-09-25 | 2022-03-31 | ハウスウェルネスフーズ株式会社 | 乳酸菌と脂肪酸を含む飼料及び組成物 |
JP7342338B2 (ja) | 2020-09-25 | 2023-09-12 | ハウスウェルネスフーズ株式会社 | 乳酸菌と脂肪酸を含む飼料及び組成物 |
CN114391493A (zh) * | 2021-12-16 | 2022-04-26 | 佛山市顺德区活宝源生物科技有限公司 | 加州鲈的捕捞方法 |
CN114391493B (zh) * | 2021-12-16 | 2023-07-04 | 佛山市顺德区活宝源生物科技有限公司 | 加州鲈的捕捞方法 |
Also Published As
Publication number | Publication date |
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JPWO2004084923A1 (ja) | 2006-06-29 |
JP4813902B2 (ja) | 2011-11-09 |
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