WO2004024933A3 - Verfahren zur fermentativen herstellung schwefelhaltiger feinchemikalien (mety) - Google Patents

Verfahren zur fermentativen herstellung schwefelhaltiger feinchemikalien (mety) Download PDF

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Publication number
WO2004024933A3
WO2004024933A3 PCT/EP2003/009453 EP0309453W WO2004024933A3 WO 2004024933 A3 WO2004024933 A3 WO 2004024933A3 EP 0309453 W EP0309453 W EP 0309453W WO 2004024933 A3 WO2004024933 A3 WO 2004024933A3
Authority
WO
WIPO (PCT)
Prior art keywords
mety
fine chemicals
containing sulphur
zymotic
production
Prior art date
Application number
PCT/EP2003/009453
Other languages
English (en)
French (fr)
Other versions
WO2004024933A2 (de
Inventor
Burkhard Kroeger
Oskar Zelder
Corinna Klopprogge
Hartwig Schroeder
Stefan Haefner
Original Assignee
Basf Ag
Burkhard Kroeger
Oskar Zelder
Corinna Klopprogge
Hartwig Schroeder
Stefan Haefner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag, Burkhard Kroeger, Oskar Zelder, Corinna Klopprogge, Hartwig Schroeder, Stefan Haefner filed Critical Basf Ag
Priority to AU2003264109A priority Critical patent/AU2003264109A1/en
Priority to JP2004535174A priority patent/JP2005537025A/ja
Priority to BR0313758-9A priority patent/BR0313758A/pt
Priority to EP03794945A priority patent/EP1537225A2/de
Priority to US10/525,710 priority patent/US7381549B2/en
Publication of WO2004024933A2 publication Critical patent/WO2004024933A2/de
Publication of WO2004024933A3 publication Critical patent/WO2004024933A3/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)

Abstract

Die Erfindung betrifft Verfahren zur fermentativen Herstellung von schwefelhaltigen Feinchemikalien, insbesondere L-Methionin, unter Verwendung von Bakterien, in denen eine für ein Methionin-Synthase (metY)-Gen kodierende Nukleotidsequenz exprimiert wird.
PCT/EP2003/009453 2002-08-26 2003-08-26 Verfahren zur fermentativen herstellung schwefelhaltiger feinchemikalien (mety) WO2004024933A2 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2003264109A AU2003264109A1 (en) 2002-08-26 2003-08-26 Method for zymotic production of fine chemicals (mety) containing sulphur
JP2004535174A JP2005537025A (ja) 2002-08-26 2003-08-26 発酵による硫黄含有ファインケミカルの製造方法
BR0313758-9A BR0313758A (pt) 2002-08-26 2003-08-26 Processos para a produção fermentativa de pelo menos um produto quìmico fino contendo enxofre, e para a produção de um aditivo de ração animal contendo l-metionina a partir de caldos de fermentação
EP03794945A EP1537225A2 (de) 2002-08-26 2003-08-26 Verfahren zur fermentativen herstellung schwefelhaltiger feinchemikalien (mety)
US10/525,710 US7381549B2 (en) 2002-08-26 2003-08-26 Method for zymotic production of fine chemicals (mety) containing sulphur

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10239082.7 2002-08-26
DE10239082A DE10239082A1 (de) 2002-08-26 2002-08-26 Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien

Publications (2)

Publication Number Publication Date
WO2004024933A2 WO2004024933A2 (de) 2004-03-25
WO2004024933A3 true WO2004024933A3 (de) 2004-04-22

Family

ID=31197387

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/009453 WO2004024933A2 (de) 2002-08-26 2003-08-26 Verfahren zur fermentativen herstellung schwefelhaltiger feinchemikalien (mety)

Country Status (9)

Country Link
US (1) US7381549B2 (de)
EP (1) EP1537225A2 (de)
JP (1) JP2005537025A (de)
KR (1) KR20050034747A (de)
CN (1) CN100523208C (de)
AU (1) AU2003264109A1 (de)
BR (1) BR0313758A (de)
DE (1) DE10239082A1 (de)
WO (1) WO2004024933A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10239073A1 (de) 2002-08-26 2004-03-11 Basf Ag Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien
DE10239308A1 (de) 2002-08-27 2004-03-11 Basf Ag Verfahren zur fermentativen Herstellung von schwefelhaltigen Feinchemikalien
AU2004245988A1 (en) * 2003-05-30 2004-12-16 Microbia, Inc. Methods and compositions for amino acid production
DE10359668A1 (de) 2003-12-18 2005-07-14 Basf Ag Verfahren zur Herstellung von Methionin
WO2006138689A2 (en) * 2005-06-17 2006-12-28 Microbia, Inc. Improved amino acid and metabolite biosynthesis
JP2009501550A (ja) * 2005-07-18 2009-01-22 ビーエーエスエフ ソシエタス・ヨーロピア メチオニン生産組換え微生物
US20090221027A1 (en) * 2005-07-18 2009-09-03 Basf Ag Use of a bacillus meti gene to improve methionine production in microorganisms
CA2615315C (en) * 2005-07-18 2015-10-06 Basf Aktiengesellschaft Use of dimethyl disulfide for methionine production in microorganisms
DE102006004063A1 (de) * 2006-01-28 2007-08-02 Degussa Gmbh Verfahren zur Herstellung von Methionin aus Homoserin
EP3807415A1 (de) * 2018-06-13 2021-04-21 Engenes Biotech GmbH Synthese eines methionin-analogons
CN112126666B (zh) * 2020-09-22 2022-04-08 廊坊梅花生物技术开发有限公司 核苷高产菌及其构建方法与应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017112A1 (en) * 1992-02-20 1993-09-02 Genencor International, Inc. Biosynthesis of methionine using a reduced source of sulfur
WO2002010206A2 (en) * 2000-08-02 2002-02-07 Degussa Ag Nucleotide sequences which code for the metf gene
WO2002010209A1 (en) * 2000-08-02 2002-02-07 Degussa Ag Nucleotide sequences which code for the meth gene
WO2002018613A1 (en) * 2000-09-02 2002-03-07 Degussa Ag NUCLEOTIDE SEQUENCES WHICH CODE FOR THE metY GENE
WO2002097096A2 (en) * 2001-05-30 2002-12-05 Degussa Ag Nucleotide sequences which code for the metd gene

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
JPS5835197A (ja) 1981-08-26 1983-03-01 Kyowa Hakko Kogyo Co Ltd プラスミドｐｃｇ２
US4601893A (en) 1984-02-08 1986-07-22 Pfizer Inc. Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
GB2165546B (en) 1984-08-21 1989-05-17 Asahi Chemical Ind A plasmid containing a gene for tetracycline resistance and dna fragments derived therefrom
DE4027453A1 (de) 1990-08-30 1992-03-05 Degussa Neue plasmide aus corynebacterium glutamicum und davon abgeleitete plasmidvektoren
DE4440118C1 (de) 1994-11-11 1995-11-09 Forschungszentrum Juelich Gmbh Die Genexpression in coryneformen Bakterien regulierende DNA
JPH10229891A (ja) 1997-02-20 1998-09-02 Mitsubishi Rayon Co Ltd マロン酸誘導体の製造法
JP4623825B2 (ja) 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
DE10046870A1 (de) 2000-09-20 2002-03-28 Basf Ag Verfahren zur Veränderung des Genoms von Corynebakterien
DE10217058A1 (de) 2002-04-17 2003-11-27 Basf Ag Verfahren zur Herstellung von schwefelhaltigen Feinchemikalien
DE10222858A1 (de) 2002-05-23 2003-12-04 Basf Ag Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien
DE10239073A1 (de) 2002-08-26 2004-03-11 Basf Ag Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien
DE10239308A1 (de) 2002-08-27 2004-03-11 Basf Ag Verfahren zur fermentativen Herstellung von schwefelhaltigen Feinchemikalien

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017112A1 (en) * 1992-02-20 1993-09-02 Genencor International, Inc. Biosynthesis of methionine using a reduced source of sulfur
WO2002010206A2 (en) * 2000-08-02 2002-02-07 Degussa Ag Nucleotide sequences which code for the metf gene
WO2002010209A1 (en) * 2000-08-02 2002-02-07 Degussa Ag Nucleotide sequences which code for the meth gene
WO2002018613A1 (en) * 2000-09-02 2002-03-07 Degussa Ag NUCLEOTIDE SEQUENCES WHICH CODE FOR THE metY GENE
WO2002097096A2 (en) * 2001-05-30 2002-12-05 Degussa Ag Nucleotide sequences which code for the metd gene

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HWANG BYUNG-JOON ET AL: "Corynebacterium glutamicum utilizes both transsulfuration and direct sulfhydrylation pathways for methionine biosynthesis", JOURNAL OF BACTERIOLOGY, vol. 184, no. 5, March 2002 (2002-03-01), pages 1277 - 1286, XP002269798, ISSN: 0021-9193 *
REY DANIEL ALEXANDER ET AL: "The putative transcriptional repressor McbR, member of the TetR-family, is involved in the regulation of the metabolic network directing the synthesis of sulfur containing amino acids in Corynebacterium glutamicum.", JOURNAL OF BIOTECHNOLOGY, vol. 103, no. 1, 12 June 2003 (2003-06-12), pages 51 - 65, XP001152914, ISSN: 0168-1656 (ISSN print) *

Also Published As

Publication number Publication date
KR20050034747A (ko) 2005-04-14
BR0313758A (pt) 2005-06-21
WO2004024933A2 (de) 2004-03-25
CN1756847A (zh) 2006-04-05
JP2005537025A (ja) 2005-12-08
EP1537225A2 (de) 2005-06-08
DE10239082A1 (de) 2004-03-04
US20050260721A1 (en) 2005-11-24
AU2003264109A1 (en) 2004-04-30
CN100523208C (zh) 2009-08-05
US7381549B2 (en) 2008-06-03

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