WO2003087386A3 - Verfahren zur fermentiven herstellung von schwefelhaltigen feinchemikalien unter verwendung von meth-kodierenden coryneformen bakterien - Google Patents

Verfahren zur fermentiven herstellung von schwefelhaltigen feinchemikalien unter verwendung von meth-kodierenden coryneformen bakterien Download PDF

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Publication number
WO2003087386A3
WO2003087386A3 PCT/EP2003/004010 EP0304010W WO03087386A3 WO 2003087386 A3 WO2003087386 A3 WO 2003087386A3 EP 0304010 W EP0304010 W EP 0304010W WO 03087386 A3 WO03087386 A3 WO 03087386A3
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WO
WIPO (PCT)
Prior art keywords
fermentation
methods
meth
coding
fine chemicals
Prior art date
Application number
PCT/EP2003/004010
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English (en)
French (fr)
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WO2003087386A2 (de
Inventor
Burkhard Kroeger
Oskar Zelder
Corinna Klopprogge
Hartwig Schroeder
Stefan Haefner
Original Assignee
Basf Ag
Burkhard Kroeger
Oskar Zelder
Corinna Klopprogge
Hartwig Schroeder
Stefan Haefner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag, Burkhard Kroeger, Oskar Zelder, Corinna Klopprogge, Hartwig Schroeder, Stefan Haefner filed Critical Basf Ag
Priority to US10/511,302 priority Critical patent/US7485444B2/en
Priority to JP2003584324A priority patent/JP2005522218A/ja
Priority to CA002481761A priority patent/CA2481761A1/en
Priority to AU2003229691A priority patent/AU2003229691A1/en
Priority to EP03722500A priority patent/EP1497443A2/de
Priority to KR10-2004-7016606A priority patent/KR20040099451A/ko
Publication of WO2003087386A2 publication Critical patent/WO2003087386A2/de
Publication of WO2003087386A3 publication Critical patent/WO2003087386A3/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fodder In General (AREA)

Abstract

Die Erfindung betrifft Verfahren zur fermentativen Herstellung von Feinchemikalien, insbesondere L-Methionin, unt er Verwendung von Bakterien, in denen eine für ein Methionin-Synthase metH-Gen kodierende Nukleotidsequenzen exprimiert wir d.
PCT/EP2003/004010 2002-04-17 2003-04-16 Verfahren zur fermentiven herstellung von schwefelhaltigen feinchemikalien unter verwendung von meth-kodierenden coryneformen bakterien WO2003087386A2 (de)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US10/511,302 US7485444B2 (en) 2002-04-17 2003-04-16 Methods for producing sulphurous fine chemicals by fermentation using metH-coding cornyeform bacteria
JP2003584324A JP2005522218A (ja) 2002-04-17 2003-04-16 ｍｅｔＨをコードするコリネ型細菌を用いる硫黄含有ファインケミカルの発酵による生産方法
CA002481761A CA2481761A1 (en) 2002-04-17 2003-04-16 Methods for producing sulphurous fine chemicals by fermentation using meth-coding coryneform bacteria
AU2003229691A AU2003229691A1 (en) 2002-04-17 2003-04-16 Methods for producing sulphurous fine chemicals by fermentation using meth-coding coryneform bacteria
EP03722500A EP1497443A2 (de) 2002-04-17 2003-04-16 Verfahren zur fermentiven herstellung von schwefelhaltigen feinchemikalien unter verwendung von meth-kodierenden coryneformen bakterien
KR10-2004-7016606A KR20040099451A (ko) 2002-04-17 2003-04-16 ｍｅｔＨ-코딩 코리네형 박테리아를 사용하는 발효법에의한 황-함유 정밀화학물질의 생산 방법

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10217058.4 2002-04-17
DE10217058A DE10217058A1 (de) 2002-04-17 2002-04-17 Verfahren zur Herstellung von schwefelhaltigen Feinchemikalien

Publications (2)

Publication Number Publication Date
WO2003087386A2 WO2003087386A2 (de) 2003-10-23
WO2003087386A3 true WO2003087386A3 (de) 2004-04-08

Family

ID=29224528

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/004010 WO2003087386A2 (de) 2002-04-17 2003-04-16 Verfahren zur fermentiven herstellung von schwefelhaltigen feinchemikalien unter verwendung von meth-kodierenden coryneformen bakterien

Country Status (9)

Country Link
US (1) US7485444B2 (de)
EP (1) EP1497443A2 (de)
JP (1) JP2005522218A (de)
KR (1) KR20040099451A (de)
CN (1) CN1653186A (de)
AU (1) AU2003229691A1 (de)
CA (1) CA2481761A1 (de)
DE (1) DE10217058A1 (de)
WO (1) WO2003087386A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10239073A1 (de) * 2002-08-26 2004-03-11 Basf Ag Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien
DE10239082A1 (de) 2002-08-26 2004-03-04 Basf Ag Verfahren zur fermentativen Herstellung schwefelhaltiger Feinchemikalien
DE10239308A1 (de) 2002-08-27 2004-03-11 Basf Ag Verfahren zur fermentativen Herstellung von schwefelhaltigen Feinchemikalien
GB0326194D0 (en) * 2003-11-10 2003-12-17 Univ Kent Canterbury Proteins involved in signal transduction
DE10359668A1 (de) * 2003-12-18 2005-07-14 Basf Ag Verfahren zur Herstellung von Methionin
KR100651220B1 (ko) * 2004-06-29 2006-11-29 씨제이 주식회사 Ｌ-메씨오닌 생산 균주 및 상기 균주를 이용한ｌ-메씨오닌의 생산방법
CA2615416A1 (en) * 2005-07-18 2007-01-25 Basf Aktiengesellschaft Methionine producing recombinant microorganisms
MX298012B (es) 2007-07-06 2012-11-04 Basf Se Metodo para la produccion de una solucion de glucosa acuosa a partir de maiz.
GB0816854D0 (en) * 2008-09-15 2008-10-22 Univ The West Of Scotland Anti protozoa compounds
AR083468A1 (es) 2010-10-25 2013-02-27 Metabolic Explorer Sa Aumento de la disponibilidad de nadph para la produccion de metionina
CN103289928B (zh) * 2013-05-31 2015-03-04 浙江工业大学 荧光假单胞菌及其在生物合成蛋氨酸中的应用
CN103757019B (zh) * 2013-12-23 2015-12-30 青岛蔚蓝生物集团有限公司 一种启动子及表达外源蛋白的重组表达系统
WO2017009009A1 (en) * 2015-07-10 2017-01-19 Evonik Degussa Gmbh Amino acid production
EP4450621A1 (de) 2021-12-13 2024-10-23 Kao Corporation Neuer promotor

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0375889A2 (de) * 1988-12-09 1990-07-04 Degussa Aktiengesellschaft Verfahren zur ortsspezifischen Mutagenese von DNA und Entwicklung von Plasmidvektoren
WO2002010209A1 (en) * 2000-08-02 2002-02-07 Degussa Ag Nucleotide sequences which code for the meth gene

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5835197A (ja) 1981-08-26 1983-03-01 Kyowa Hakko Kogyo Co Ltd プラスミドｐｃｇ２
US4601893A (en) 1984-02-08 1986-07-22 Pfizer Inc. Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
GB2165546B (en) 1984-08-21 1989-05-17 Asahi Chemical Ind A plasmid containing a gene for tetracycline resistance and dna fragments derived therefrom
DE4027453A1 (de) 1990-08-30 1992-03-05 Degussa Neue plasmide aus corynebacterium glutamicum und davon abgeleitete plasmidvektoren
DE4440118C1 (de) 1994-11-11 1995-11-09 Forschungszentrum Juelich Gmbh Die Genexpression in coryneformen Bakterien regulierende DNA
JPH10229891A (ja) 1997-02-20 1998-09-02 Mitsubishi Rayon Co Ltd マロン酸誘導体の製造法
JP4623825B2 (ja) 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
DE10046870A1 (de) 2000-09-20 2002-03-28 Basf Ag Verfahren zur Veränderung des Genoms von Corynebakterien

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0375889A2 (de) * 1988-12-09 1990-07-04 Degussa Aktiengesellschaft Verfahren zur ortsspezifischen Mutagenese von DNA und Entwicklung von Plasmidvektoren
WO2002010209A1 (en) * 2000-08-02 2002-02-07 Degussa Ag Nucleotide sequences which code for the meth gene

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 April 2001 (2001-04-01), "Putative methionine synthase", XP002254343, retrieved from EBI Database accession no. q9ewh3 *

Also Published As

Publication number Publication date
US20060223149A1 (en) 2006-10-05
CA2481761A1 (en) 2003-10-23
AU2003229691A8 (en) 2003-10-27
EP1497443A2 (de) 2005-01-19
KR20040099451A (ko) 2004-11-26
WO2003087386A2 (de) 2003-10-23
US7485444B2 (en) 2009-02-03
JP2005522218A (ja) 2005-07-28
AU2003229691A1 (en) 2003-10-27
CN1653186A (zh) 2005-08-10
DE10217058A1 (de) 2003-11-27

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