WO2003048174A1 - Procede de preparation de composes diphosphine et intermediaires pour ce procede - Google Patents
Procede de preparation de composes diphosphine et intermediaires pour ce procede Download PDFInfo
- Publication number
- WO2003048174A1 WO2003048174A1 PCT/JP2002/012758 JP0212758W WO03048174A1 WO 2003048174 A1 WO2003048174 A1 WO 2003048174A1 JP 0212758 W JP0212758 W JP 0212758W WO 03048174 A1 WO03048174 A1 WO 03048174A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- preparation
- intermediates
- general formula
- diphosphine compounds
- iii
- Prior art date
Links
- VURFVHCLMJOLKN-UHFFFAOYSA-N diphosphane Chemical class PP VURFVHCLMJOLKN-UHFFFAOYSA-N 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- BWJRMVLPCQPWGR-UHFFFAOYSA-N boron;phosphane Chemical compound [B].P BWJRMVLPCQPWGR-UHFFFAOYSA-N 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
- C07F9/65517—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B53/00—Asymmetric syntheses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5027—Polyphosphines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5045—Complexes or chelates of phosphines with metallic compounds or metals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/505—Preparation; Separation; Purification; Stabilisation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002354100A AU2002354100A1 (en) | 2001-12-07 | 2002-12-05 | Process for preparation of diphosphine compounds and intermediates for the process |
DE60233256T DE60233256D1 (de) | 2001-12-07 | 2002-12-05 | Verfahren zur herstellung von diphosphinverbindungen und zwischenprodukte für das verfahren |
KR1020047008777A KR100929514B1 (ko) | 2001-12-07 | 2002-12-05 | 디포스핀 화합물의 제조 방법 및 그 방법을 위한 중간체 |
EP02786039A EP1452537B1 (en) | 2001-12-07 | 2002-12-05 | Process for preparation of diphosphine compounds and intermediates for the process |
AT02786039T ATE438653T1 (de) | 2001-12-07 | 2002-12-05 | Verfahren zur herstellung von diphosphinverbindungen und zwischenprodukte für das verfahren |
US10/497,808 US7208633B2 (en) | 2001-12-07 | 2002-12-05 | Process for preparation of diphosphine compounds and intermediates for the process |
US11/682,630 US7678942B2 (en) | 2001-12-07 | 2007-03-06 | Process for preparation of diphosphine compounds and intermediates for the process |
US12/694,658 US8053604B2 (en) | 2001-12-07 | 2010-01-27 | Process for preparation of diphosphine compounds and intermediates for the process |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001374909 | 2001-12-07 | ||
JP2001-374909 | 2001-12-07 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10497808 A-371-Of-International | 2002-12-05 | ||
US11/682,630 Division US7678942B2 (en) | 2001-12-07 | 2007-03-06 | Process for preparation of diphosphine compounds and intermediates for the process |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003048174A1 true WO2003048174A1 (fr) | 2003-06-12 |
Family
ID=19183384
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/012758 WO2003048174A1 (fr) | 2001-12-07 | 2002-12-05 | Procede de preparation de composes diphosphine et intermediaires pour ce procede |
Country Status (9)
Country | Link |
---|---|
US (3) | US7208633B2 (ja) |
EP (1) | EP1452537B1 (ja) |
JP (1) | JP5043883B2 (ja) |
KR (1) | KR100929514B1 (ja) |
CN (2) | CN100519569C (ja) |
AT (1) | ATE438653T1 (ja) |
AU (1) | AU2002354100A1 (ja) |
DE (1) | DE60233256D1 (ja) |
WO (1) | WO2003048174A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004050667A1 (ja) * | 2002-12-05 | 2004-06-17 | Takeda Pharmaceutical Company Limited | ジホスフィン化合物を配位子とする遷移金属錯体 |
EP2420507A1 (en) | 2005-09-20 | 2012-02-22 | Takeda Pharmaceutical Company Limited | Diphosphine ligand and transition metal complex using the same |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE438653T1 (de) * | 2001-12-07 | 2009-08-15 | Takeda Pharmaceutical | Verfahren zur herstellung von diphosphinverbindungen und zwischenprodukte für das verfahren |
KR101085803B1 (ko) | 2003-05-19 | 2011-11-22 | 다케다 야쿠힌 고교 가부시키가이샤 | 포스핀-보레인 착물의 제조 방법 |
US7669362B2 (en) * | 2003-07-31 | 2010-03-02 | Basf Aktiengesellschaft | Trap for catching woodland, garden and agricultural insect pests and method for trapping and storing woodland, garden and agricultural insect pests |
GB0515082D0 (en) | 2005-07-22 | 2005-08-31 | Rhodia Uk Ltd | Bisphosphines |
JP5124210B2 (ja) * | 2007-08-24 | 2013-01-23 | 日本化学工業株式会社 | ビアリールホスフィン化合物の製造方法 |
CN103819508A (zh) * | 2014-02-10 | 2014-05-28 | 江苏长青农化股份有限公司 | 二(3,5-二甲基苯基)氧化磷的合成方法 |
CN106458897A (zh) * | 2014-03-14 | 2017-02-22 | 武田药品工业株式会社 | 制备杂环化合物的方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2926194A (en) * | 1957-06-17 | 1960-02-23 | American Potash & Chem Corp | Phosphine borine compounds and their preparation |
JPH03255090A (ja) | 1990-03-01 | 1991-11-13 | Takasago Internatl Corp | 2,2’―ビス〔ジ―(3,5―ジアルキルフェニル)ホスフィノ〕―1,1’―ビナフチル及びこれを配位子とする遷移金属錯体 |
US5399771A (en) * | 1994-06-01 | 1995-03-21 | Merck & Co., Inc. | Process of synthesizing binaphthyl derivatives |
EP0754696A1 (en) | 1995-07-21 | 1997-01-22 | Takasago International Corporation | Chiral unsymmetric diphosphine compounds and transition metal complexes containing them as ligands |
WO1998042716A1 (en) * | 1997-03-26 | 1998-10-01 | Nsc Technologies Llc | Preparation of tertiary phosphines via nickel-catalyzed cross coupling |
JP2000136194A (ja) * | 1998-08-25 | 2000-05-16 | Takeda Chem Ind Ltd | ホスフィノビナフチルの製造法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3770639B2 (ja) | 1995-10-31 | 2006-04-26 | 高砂香料工業株式会社 | 光学活性ジホスフィンの製造方法 |
JP3148136B2 (ja) | 1996-12-26 | 2001-03-19 | 高砂香料工業株式会社 | 新規なキラルジホスフィン化合物、その製造中間体、該ジホス フィン化合物を配位子とする遷移金属錯体並びに該錯体を含む 不斉水素化触媒 |
JP3255090B2 (ja) | 1997-08-22 | 2002-02-12 | 松下電器産業株式会社 | チップの実装構造およびバンプの形成方法 |
JP2000007688A (ja) | 1998-06-18 | 2000-01-11 | Kankyo Kagaku Center:Kk | 光学活性2,2′−ビス(ジ置換ホスフィノ)−1,1′−ビナフチルの製造法 |
ATE438653T1 (de) * | 2001-12-07 | 2009-08-15 | Takeda Pharmaceutical | Verfahren zur herstellung von diphosphinverbindungen und zwischenprodukte für das verfahren |
JP4198354B2 (ja) * | 2001-12-28 | 2008-12-17 | 関東化学株式会社 | 光学活性ジホスフィン配位子 |
EP1568701B1 (en) * | 2002-12-05 | 2010-01-20 | Takeda Pharmaceutical Company Limited | Transition metal complex having diphosphine complex as ligand |
JP4489416B2 (ja) | 2002-12-05 | 2010-06-23 | 武田薬品工業株式会社 | ジホスフィン化合物を配位子とする遷移金属錯体 |
-
2002
- 2002-12-05 AT AT02786039T patent/ATE438653T1/de active
- 2002-12-05 EP EP02786039A patent/EP1452537B1/en not_active Expired - Lifetime
- 2002-12-05 WO PCT/JP2002/012758 patent/WO2003048174A1/ja active Application Filing
- 2002-12-05 CN CNB028279069A patent/CN100519569C/zh not_active Expired - Fee Related
- 2002-12-05 US US10/497,808 patent/US7208633B2/en not_active Expired - Lifetime
- 2002-12-05 KR KR1020047008777A patent/KR100929514B1/ko not_active IP Right Cessation
- 2002-12-05 CN CN2009102033780A patent/CN101580518B/zh not_active Expired - Fee Related
- 2002-12-05 AU AU2002354100A patent/AU2002354100A1/en not_active Abandoned
- 2002-12-05 DE DE60233256T patent/DE60233256D1/de not_active Expired - Lifetime
-
2007
- 2007-03-06 US US11/682,630 patent/US7678942B2/en not_active Expired - Lifetime
-
2009
- 2009-04-10 JP JP2009096377A patent/JP5043883B2/ja not_active Expired - Lifetime
-
2010
- 2010-01-27 US US12/694,658 patent/US8053604B2/en not_active Expired - Fee Related
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2926194A (en) * | 1957-06-17 | 1960-02-23 | American Potash & Chem Corp | Phosphine borine compounds and their preparation |
JPH03255090A (ja) | 1990-03-01 | 1991-11-13 | Takasago Internatl Corp | 2,2’―ビス〔ジ―(3,5―ジアルキルフェニル)ホスフィノ〕―1,1’―ビナフチル及びこれを配位子とする遷移金属錯体 |
US5399771A (en) * | 1994-06-01 | 1995-03-21 | Merck & Co., Inc. | Process of synthesizing binaphthyl derivatives |
EP0754696A1 (en) | 1995-07-21 | 1997-01-22 | Takasago International Corporation | Chiral unsymmetric diphosphine compounds and transition metal complexes containing them as ligands |
WO1998042716A1 (en) * | 1997-03-26 | 1998-10-01 | Nsc Technologies Llc | Preparation of tertiary phosphines via nickel-catalyzed cross coupling |
JP2000136194A (ja) * | 1998-08-25 | 2000-05-16 | Takeda Chem Ind Ltd | ホスフィノビナフチルの製造法 |
Non-Patent Citations (2)
Title |
---|
LIPSHUTZ B.H. ET AL.: "Pd(0)-mediated couplings of aryl nonaflates and triflates with diphenylphosphine-borane. Preparation of BH3-stabilized, unsymmetrical triarylphosphines", TETRAHEDRON LETTERS, vol. 40, no. 2, 1999, pages 201 - 204, XP004152510 * |
MCKINSTRY L. & LIVINGHOUSE T.: "An efficient procedure for the synthesis of C-chiral bisphosphines", TETRAHEDRON, vol. 51, no. 28, 1995, pages 7655 - 7666, XP002965826 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004050667A1 (ja) * | 2002-12-05 | 2004-06-17 | Takeda Pharmaceutical Company Limited | ジホスフィン化合物を配位子とする遷移金属錯体 |
EP2420507A1 (en) | 2005-09-20 | 2012-02-22 | Takeda Pharmaceutical Company Limited | Diphosphine ligand and transition metal complex using the same |
Also Published As
Publication number | Publication date |
---|---|
JP5043883B2 (ja) | 2012-10-10 |
ATE438653T1 (de) | 2009-08-15 |
CN101580518A (zh) | 2009-11-18 |
EP1452537B1 (en) | 2009-08-05 |
EP1452537A1 (en) | 2004-09-01 |
KR20040061022A (ko) | 2004-07-06 |
US20070161805A1 (en) | 2007-07-12 |
CN101580518B (zh) | 2012-05-23 |
US7678942B2 (en) | 2010-03-16 |
CN100519569C (zh) | 2009-07-29 |
EP1452537A4 (en) | 2006-04-05 |
US20100125153A1 (en) | 2010-05-20 |
DE60233256D1 (de) | 2009-09-17 |
US8053604B2 (en) | 2011-11-08 |
KR100929514B1 (ko) | 2009-12-03 |
JP2009185050A (ja) | 2009-08-20 |
US7208633B2 (en) | 2007-04-24 |
US20050027124A1 (en) | 2005-02-03 |
AU2002354100A1 (en) | 2003-06-17 |
CN1617876A (zh) | 2005-05-18 |
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