WO2003042383A1 - Promoteurs de replication de l'adn, facteurs associes a l'adn polymerase et utilisation de ces derniers - Google Patents

Promoteurs de replication de l'adn, facteurs associes a l'adn polymerase et utilisation de ces derniers Download PDF

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Publication number
WO2003042383A1
WO2003042383A1 PCT/JP2002/011884 JP0211884W WO03042383A1 WO 2003042383 A1 WO2003042383 A1 WO 2003042383A1 JP 0211884 W JP0211884 W JP 0211884W WO 03042383 A1 WO03042383 A1 WO 03042383A1
Authority
WO
WIPO (PCT)
Prior art keywords
dna
dna polymerase
integer
synthesis
dna synthesis
Prior art date
Application number
PCT/JP2002/011884
Other languages
English (en)
French (fr)
Inventor
Masao Kitabayashi
Toshihiro Kuroita
Yoshikazu Ishida
Hideyuki Komatsubara
Yoshiaki Nishiya
Masanori Oka
Yoshihisa Kawamura
Tadayuki Imanaka
Original Assignee
Toyo Boseki Kabushiki Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2001349173A external-priority patent/JP2003144169A/ja
Priority claimed from JP2002311596A external-priority patent/JP4300321B2/ja
Application filed by Toyo Boseki Kabushiki Kaisha filed Critical Toyo Boseki Kabushiki Kaisha
Priority to EP02780096A priority Critical patent/EP1452593B1/en
Priority to DE60231901T priority patent/DE60231901D1/de
Priority to US10/495,581 priority patent/US7384739B2/en
Publication of WO2003042383A1 publication Critical patent/WO2003042383A1/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6846—Common amplification features
PCT/JP2002/011884 2001-11-14 2002-11-14 Promoteurs de replication de l'adn, facteurs associes a l'adn polymerase et utilisation de ces derniers WO2003042383A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP02780096A EP1452593B1 (en) 2001-11-14 2002-11-14 Dna synthesis promoters, dna polymerase-associated factors and utilization thereof
DE60231901T DE60231901D1 (de) 2001-11-14 2002-11-14 Dna-synthesepromotoren, mit dna-polymerase assoziierte faktoren und nutzung davon
US10/495,581 US7384739B2 (en) 2001-11-14 2002-11-14 Compositions for enhancing DNA synthesis, DNA polymerase-related factors and utilization thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2001-349173 2001-11-14
JP2001349173A JP2003144169A (ja) 2001-11-14 2001-11-14 Ｄｎａ合成反応を促進する添加剤
JP2002311596A JP4300321B2 (ja) 2002-10-25 2002-10-25 Ｄｎａ合成反応を促進する方法、およびそのための組成物
JP2002-311596 2002-10-25

Publications (1)

Publication Number Publication Date
WO2003042383A1 true WO2003042383A1 (fr) 2003-05-22

Family

ID=26624518

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/011884 WO2003042383A1 (fr) 2001-11-14 2002-11-14 Promoteurs de replication de l'adn, facteurs associes a l'adn polymerase et utilisation de ces derniers

Country Status (5)

Country Link
US (1) US7384739B2 (ja)
EP (1) EP1452593B1 (ja)
AT (1) ATE427992T1 (ja)
DE (1) DE60231901D1 (ja)
WO (1) WO2003042383A1 (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
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WO2004099446A1 (ja) * 2003-05-07 2004-11-18 Takara Bio Inc. 遺伝子導入部位の解析方法
US8048987B2 (en) 2004-06-04 2011-11-01 Takara Bio Inc. Polypeptides having DNA polymerase activity
US8465924B2 (en) * 2004-12-07 2013-06-18 Sysmex Corporation Treatment solution for preparing sample solution for nucleic acid amplification reaction and method for detecting nucleic acid by using treatment solution
CN104093835A (zh) * 2012-01-31 2014-10-08 宝生物工程株式会社 用于改进核酸合成反应的方法
JP2016028574A (ja) * 2008-09-30 2016-03-03 アボツト・モレキユラー・インコーポレイテツド 試験サンプル中のヒトパピローマウイルスおよびヒトベータグロビン配列を検出するためのプライマーおよびプローブ

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KR20080031255A (ko) * 2005-07-04 2008-04-08 셀레스타 렉시코-사이언시즈 가부시키가이샤 변이형 ｐｃｎａ
CA2765167A1 (en) * 2009-06-12 2010-12-16 Nanectis Biotechnologies A highly sensitive method for detection of viral hiv dna remaining after antiretroviral therapy of aids patients
JP5201218B2 (ja) 2009-06-15 2013-06-05 トヨタ自動車株式会社 無細胞タンパク質合成溶液、無細胞タンパク質合成キット及びタンパク質合成方法
EP2600901B1 (en) 2010-08-06 2019-03-27 ModernaTX, Inc. A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
ES2737960T3 (es) 2010-10-01 2020-01-17 Modernatx Inc Nucleósidos, nucleótidos y ácidos nucleicos modificados y sus usos
AU2012236099A1 (en) 2011-03-31 2013-10-03 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP3682905B1 (en) 2011-10-03 2021-12-01 ModernaTX, Inc. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
EP2791160B1 (en) 2011-12-16 2022-03-02 ModernaTX, Inc. Modified mrna compositions
AU2013243948A1 (en) 2012-04-02 2014-10-30 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins associated with human disease
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9303079B2 (en) 2012-04-02 2016-04-05 Moderna Therapeutics, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
JP6478444B2 (ja) * 2012-09-28 2019-03-06 東洋紡株式会社 改変された耐熱性ｄｎａポリメラーゼ
UA117921C2 (uk) * 2012-10-22 2018-10-25 Байєр Кропсаєнс Нв Композиція, пристрій та спосіб ампліфікації нуклеїнових кислот
EP4074834A1 (en) 2012-11-26 2022-10-19 ModernaTX, Inc. Terminally modified rna
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
US20160194625A1 (en) 2013-09-03 2016-07-07 Moderna Therapeutics, Inc. Chimeric polynucleotides
CA2926218A1 (en) 2013-10-03 2015-04-09 Moderna Therapeutics, Inc. Polynucleotides encoding low density lipoprotein receptor
CA2955250A1 (en) 2014-07-16 2016-01-21 Moderna Therapeutics, Inc. Chimeric polynucleotides
EP3763825B1 (en) * 2015-01-23 2023-10-04 Qiagen Sciences, LLC High multiplex pcr with molecular barcoding
HRP20220525T1 (hr) 2015-12-23 2022-05-27 Modernatx, Inc. Postupci uporabe polinukleotida koji kodiraju ligand ox40
WO2017120612A1 (en) 2016-01-10 2017-07-13 Modernatx, Inc. Therapeutic mrnas encoding anti ctla-4 antibodies
JP6934477B2 (ja) 2016-01-19 2021-09-15 ボード オブ リージェンツ ザ ユニヴァーシティ オブ テキサス システム 熱安定逆転写酵素
RU2769316C2 (ru) 2016-05-18 2022-03-30 МОДЕРНАТиЭкс, ИНК. Полинуклеотиды, кодирующие интерлейкин-12 (il12), и их применения
PL3458474T3 (pl) 2016-05-18 2022-11-14 Modernatx, Inc. Kombinacje mrna kodujących polipeptydy immunomodulujące i ich zastosowania
US20200131498A1 (en) 2017-06-14 2020-04-30 Modernatx, Inc. Polynucleotides encoding methylmalonyl-coa mutase
WO2019084538A1 (en) 2017-10-27 2019-05-02 Board Of Regents, The University Of Texas System TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF

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EP0726310A1 (en) 1995-02-10 1996-08-14 Gen-Probe Incorporated Stabilized enzyme compositons for nucleic acid amplification
WO1996034115A1 (fr) 1995-04-27 1996-10-31 Cis Bio International Tampon et methode d'evaluation des conditions optimales d'amplification de sequences cibles d'acide nucleique, et leurs applications
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EP0997530B1 (en) 1997-06-26 2006-08-23 Takara Bio Inc. Dna polymerase-related factors
EP1208210A2 (en) 1999-07-30 2002-05-29 Stratagene Archaeal replication accessory factors and methods of use
DE19937230A1 (de) 1999-08-06 2001-02-08 Lion Bioscience Ag Chimäre Proteine

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EP0726310A1 (en) 1995-02-10 1996-08-14 Gen-Probe Incorporated Stabilized enzyme compositons for nucleic acid amplification
WO1996034115A1 (fr) 1995-04-27 1996-10-31 Cis Bio International Tampon et methode d'evaluation des conditions optimales d'amplification de sequences cibles d'acide nucleique, et leurs applications
EP0771870A1 (en) * 1995-08-25 1997-05-07 F. Hoffmann-La Roche Ag Reversible inactivation of thermostable enzymes by using dicarboxylic acid anhydride and use in amplification methods
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WO1999046400A1 (en) 1998-03-13 1999-09-16 Life Technologies, Inc. Compositions and methods for enhanced synthesis of nucleic acid molecules

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004099446A1 (ja) * 2003-05-07 2004-11-18 Takara Bio Inc. 遺伝子導入部位の解析方法
US8048987B2 (en) 2004-06-04 2011-11-01 Takara Bio Inc. Polypeptides having DNA polymerase activity
EP2292767A3 (en) * 2004-06-04 2011-12-07 Takara Bio, Inc. Polypepdides having DNA polymerase activity
US8344105B2 (en) 2004-06-04 2013-01-01 Takara Bio Inc. Polypeptides having DNA polymerase activity
US8465924B2 (en) * 2004-12-07 2013-06-18 Sysmex Corporation Treatment solution for preparing sample solution for nucleic acid amplification reaction and method for detecting nucleic acid by using treatment solution
JP2016028574A (ja) * 2008-09-30 2016-03-03 アボツト・モレキユラー・インコーポレイテツド 試験サンプル中のヒトパピローマウイルスおよびヒトベータグロビン配列を検出するためのプライマーおよびプローブ
CN104093835A (zh) * 2012-01-31 2014-10-08 宝生物工程株式会社 用于改进核酸合成反应的方法
CN104093835B (zh) * 2012-01-31 2015-12-02 宝生物工程株式会社 用于改进核酸合成反应的方法

Also Published As

Publication number Publication date
ATE427992T1 (de) 2009-04-15
EP1452593A1 (en) 2004-09-01
US7384739B2 (en) 2008-06-10
EP1452593A4 (en) 2005-11-30
EP1452593B1 (en) 2009-04-08
DE60231901D1 (de) 2009-05-20
US20050069887A1 (en) 2005-03-31

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