WO2003009859A1 - Immunotherapie pour humains - Google Patents

Immunotherapie pour humains Download PDF

Info

Publication number
WO2003009859A1
WO2003009859A1 PCT/JP2002/007337 JP0207337W WO03009859A1 WO 2003009859 A1 WO2003009859 A1 WO 2003009859A1 JP 0207337 W JP0207337 W JP 0207337W WO 03009859 A1 WO03009859 A1 WO 03009859A1
Authority
WO
WIPO (PCT)
Prior art keywords
immunotherapy
cancer
treating
humans
efficacious
Prior art date
Application number
PCT/JP2002/007337
Other languages
English (en)
French (fr)
Inventor
Akira Hayashi
Original Assignee
Azuma, Ichiro
Toyoshima, Kumao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Azuma, Ichiro, Toyoshima, Kumao filed Critical Azuma, Ichiro
Priority to EP02751649A priority Critical patent/EP1415655A4/en
Priority to JP2003515251A priority patent/JP4859341B2/ja
Priority to US10/484,079 priority patent/US7273602B2/en
Publication of WO2003009859A1 publication Critical patent/WO2003009859A1/ja
Priority to US11/723,318 priority patent/US7521040B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PCT/JP2002/007337 2001-07-19 2002-07-19 Immunotherapie pour humains WO2003009859A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP02751649A EP1415655A4 (en) 2001-07-19 2002-07-19 IMMUNOTHERAPY FOR PEOPLE
JP2003515251A JP4859341B2 (ja) 2001-07-19 2002-07-19 ヒト免疫療法
US10/484,079 US7273602B2 (en) 2001-07-19 2002-07-19 Immunotherapy for humans
US11/723,318 US7521040B2 (en) 2001-07-19 2007-03-19 Immunotherapy for humans

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001219852 2001-07-19
JP2001-219852 2001-07-19

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10484079 A-371-Of-International 2002-07-19
US11/723,318 Division US7521040B2 (en) 2001-07-19 2007-03-19 Immunotherapy for humans

Publications (1)

Publication Number Publication Date
WO2003009859A1 true WO2003009859A1 (fr) 2003-02-06

Family

ID=19053776

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/007337 WO2003009859A1 (fr) 2001-07-19 2002-07-19 Immunotherapie pour humains

Country Status (4)

Country Link
US (2) US7273602B2 (ja)
EP (1) EP1415655A4 (ja)
JP (2) JP4859341B2 (ja)
WO (1) WO2003009859A1 (ja)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8034359B2 (en) 2004-06-07 2011-10-11 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to cancers
JP2012097112A (ja) * 2004-06-07 2012-05-24 Qu Biologics Inc 癌を治療するための細菌組成物
US8501198B2 (en) 2004-06-07 2013-08-06 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US8980279B2 (en) 2010-07-26 2015-03-17 Qu Biologics Personalized site-specific immunomodulation
US9107864B2 (en) 2004-06-07 2015-08-18 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US10130692B2 (en) 2010-07-26 2018-11-20 Qu Biologics Inc. Immunogenic anti-inflammatory compositions
US10251946B2 (en) 2014-05-02 2019-04-09 Qu Biologics Inc. Anti-microbial immunomodulation

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2337445A1 (en) 1998-07-16 2000-01-27 Sumitomo Pharmaceuticals Co., Ltd. Preparations for immunotherapy for cancer having bacterial somatic constituent as the active ingredient
CN1935262B (zh) * 2005-09-23 2010-12-29 沈阳胜宝康生物制药有限公司 红色诺卡氏菌细胞壁骨架在制备抗人乳头瘤病毒药物的用途
CN101073583A (zh) * 2006-05-19 2007-11-21 沈阳胜宝康生物制药有限公司 红色诺卡氏菌细胞壁骨架在制备药物中的用途
US20080161248A1 (en) * 2006-12-28 2008-07-03 Wendye Robbins Methods and Compositions for Therapeutic Treatment
CN102526119A (zh) * 2010-12-23 2012-07-04 辽宁纳可佳生物制药有限公司 红色诺卡氏菌细胞壁骨架增强树突状细胞功能的方法
JP6074676B2 (ja) * 2011-08-19 2017-02-08 公立大学法人横浜市立大学 組織因子経路阻害因子２（ｔｆｐｉ２）測定による卵巣明細胞腺癌の検査方法および検査薬

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0958826A1 (en) * 1997-03-07 1999-11-24 Akira Hayashi Immunotherapeutic agent for cancer containing nucleoidal component of bacterium as active ingredient
WO2000003724A1 (fr) * 1998-07-16 2000-01-27 Hayashi, Akira Preparations pour immunotherapie anticancereuse comprenant un constituant somatique bacterien en tant qu'ingredient actif

Family Cites Families (13)

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JPS54140710A (en) * 1978-03-10 1979-11-01 Mitsui Toatsu Chem Inc Anti-tumor substance and its preparation
US4503048A (en) * 1982-06-30 1985-03-05 Ribi Immunochem Research, Inc. Pyridine soluble extract of a microorganism
JPS5995220A (ja) * 1982-11-22 1984-06-01 Ajinomoto Co Inc 免疫療法剤
JPS59161320A (ja) 1983-03-04 1984-09-12 Maruyama Chisato リポ多糖体およびその製造法
US4744984A (en) 1985-10-08 1988-05-17 Vetrepharm Research, Inc. Antiviral immunotherapeutic agent and preparation thereof
NZ219027A (en) * 1986-01-24 1989-09-27 Genentech Inc Antiviral composition containing interferon tumour necrosis factor and/or lymphotoxin
JPS6448154A (en) * 1987-08-19 1989-02-22 Fujitsu Ltd Bus arbitrating circuit with timeout monitor
US6284255B1 (en) * 1996-08-29 2001-09-04 Genesis Research & Development Corporation Limited Compounds and methods for treatment and diagnosis of mycobacterial infections
JPH10306029A (ja) * 1997-03-07 1998-11-17 Akira Hayashi 細菌の菌体成分を有効成分とする癌免疫療法剤
WO1998043656A1 (en) * 1997-04-02 1998-10-08 Bioniche Inc. Use of bacterial cell wall extract for preventing, treating, or eliminating a protozoal or parasitic disease
US6849452B1 (en) * 1998-03-03 2005-02-01 Institut Gustave Roussy Methods for activating natural killer (NK) cells and means for carrying out said methods
JP2002512969A (ja) * 1998-04-29 2002-05-08 アンドレアス ベーレ、 マイコバクテリウム属菌を使用する、乳頭腫ウイルス感染症の治療
US20030108527A1 (en) 1999-12-28 2003-06-12 Tsukasa Seya Maturation-promoting agent for immature dendrtic cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0958826A1 (en) * 1997-03-07 1999-11-24 Akira Hayashi Immunotherapeutic agent for cancer containing nucleoidal component of bacterium as active ingredient
WO2000003724A1 (fr) * 1998-07-16 2000-01-27 Hayashi, Akira Preparations pour immunotherapie anticancereuse comprenant un constituant somatique bacterien en tant qu'ingredient actif

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
AKIRA HAYASHI: "Kenko shihyo project series 40 gan vaccine no sayo kisaku to men'eki ryoho 2 BCG-CWS o mochiiru gan tandoku men'eki ryoho 30 nen no kiroku", ENVIRONMENT AND HEALTH, vol. 14, no. 5, October 2001 (2001-10-01), pages 259 - 270, XP002961372 *
HAYASHI A. ET AL.: "Complete cure of acute myelocyte leukemia with BCG-cell wall skeleton alone", J. HAEMATOL., vol. 102, pages 85, P-0334, XP002961371 *
HAYASHI AKIRA ET AL.: "Immuno-friendly use of BCG-cell wall skeleton remarkably improves the survival rate of various cancer patients", PROCEEDINGS OF THE JAPAN ACADEMY, SERIES B: PHYSICAL AND BIOLOGICAL SCIENCES, vol. 74, no. 3, 1998, pages 50 - 55, XP002961369 *
HAYASHI AKIRA ET AL.: "Interferon-gamma as a marker for the effective cancer immunotherapy with BCG-cell wall skeleton", PROCEEDINGS OF THE JAPAN ACADEMY, SERIES B: PHYSICAL AND BIOLOGICAL SCIENCES, vol. 70, no. 10, 1994, pages 205 - 209, XP002941985 *
KUMAO TOYOSHIMA: "Atarashii gan ryoho o motomete kakono hansei to shorai tenbo gan chiryo ni okeru men'eki kyoka no mondaiten", JAPANESE JOURNAL OF CANCER AND CHEMOTHERAPY, vol. 27, no. 6, 2000, pages 817 - 823, XP002961368 *

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200121784A1 (en) * 2004-06-07 2020-04-23 Qu Biologics Inc. Tissue Targeted Antigenic Activation of the Immune Response to Treat Cancers
JP2012097112A (ja) * 2004-06-07 2012-05-24 Qu Biologics Inc 癌を治療するための細菌組成物
US8501198B2 (en) 2004-06-07 2013-08-06 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US8034359B2 (en) 2004-06-07 2011-10-11 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to cancers
US9107864B2 (en) 2004-06-07 2015-08-18 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US9320787B2 (en) 2004-06-07 2016-04-26 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US9320788B2 (en) 2004-06-07 2016-04-26 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US9775896B2 (en) 2004-06-07 2017-10-03 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US10086066B2 (en) 2004-06-07 2018-10-02 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US8980279B2 (en) 2010-07-26 2015-03-17 Qu Biologics Personalized site-specific immunomodulation
US10130692B2 (en) 2010-07-26 2018-11-20 Qu Biologics Inc. Immunogenic anti-inflammatory compositions
US10251946B2 (en) 2014-05-02 2019-04-09 Qu Biologics Inc. Anti-microbial immunomodulation
US10946083B2 (en) 2014-05-02 2021-03-16 Qu Biologies Inc. Anti-microbial immunomodulation
US11819543B2 (en) 2014-05-02 2023-11-21 Qu Biologics Inc. Anti-microbial immunomodulation

Also Published As

Publication number Publication date
JPWO2003009859A1 (ja) 2004-11-11
US7521040B2 (en) 2009-04-21
US20040208896A1 (en) 2004-10-21
JP4964217B2 (ja) 2012-06-27
US20070172499A1 (en) 2007-07-26
US7273602B2 (en) 2007-09-25
EP1415655A1 (en) 2004-05-06
JP4859341B2 (ja) 2012-01-25
EP1415655A4 (en) 2005-12-21
JP2009102332A (ja) 2009-05-14

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