WO2002076542A1 - Seringue jetable - Google Patents

Seringue jetable Download PDF

Info

Publication number
WO2002076542A1
WO2002076542A1 PCT/DK2002/000131 DK0200131W WO02076542A1 WO 2002076542 A1 WO2002076542 A1 WO 2002076542A1 DK 0200131 W DK0200131 W DK 0200131W WO 02076542 A1 WO02076542 A1 WO 02076542A1
Authority
WO
WIPO (PCT)
Prior art keywords
plunger
cylinder
finger handle
disposable syringe
section
Prior art date
Application number
PCT/DK2002/000131
Other languages
English (en)
Inventor
Mikael Hetting
Original Assignee
Mikael Hetting
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mikael Hetting filed Critical Mikael Hetting
Publication of WO2002076542A1 publication Critical patent/WO2002076542A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5013—Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
    • A61M2005/31506—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit formed as a single piece, e.g. moulded
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5066—Means for preventing re-use by disconnection of piston and piston-rod
    • A61M2005/5073—Means for preventing re-use by disconnection of piston and piston-rod by breaking or rupturing the connection parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3213—Caps placed axially onto the needle, e.g. equipped with finger protection guards

Definitions

  • the invention relates to a disposable syringe for injecting a fluid and comprising a tubular cylinder having an attachment opening for a needle at a first end and a second opening at the opposite end, a plunger displaceable between a first position and a second position and located in the cylinder, and a finger handle connected to the plunger.
  • the disposable syringe according to Russian Patent Application SU 1816220 has a hollow plunger head and a detachable plunger rod which is receivable in the plunger head.
  • the plunger rod is provided with barbs engaging and cooperating with a recess in the hollow plunger head to thereby allow initial filling of the syringe.
  • the barbs are pushed out of the recess and folded so that refilling is not possible as the barbs are not able to engage the recess again.
  • US Patent No. 4,915,692 discloses a disposable hypodermic syringe having a cylinder and a reciprocating plunger consisting of two parts, and actuating rod and a connection link.
  • the plunger and the plunger head can move a short distance independently of each other.
  • the plunger rod has an edge portion for engaging with a recess in the interior wall of the syringe cylinder so that actuating rod and connection link are drawn away from each other if the syringe is attempted to be refilled.
  • One aspect of the present invention is to provide a disposable syringe of the kind mentioned in the opening paragraph, that has a simple structure, is easy to operate, is inexpensive to manufacture, and cannot be reused after use.
  • the finger handle in the first position of the plunger is located outside the second opening of the cylinder and inside the second opening of the cylinder in the second position of the plunger .
  • a stop can advantageously be designed in the cylinder for restricting the travel of the cylinder from the second to the first position.
  • the disposable syringe By performing a number of reciprocating plunger travels between first and second position, the disposable syringe can quickly and easily be ventilated and filled with a preset volume of injection fluid. Ventilation can be done in a known manner by collecting an undesired, possible content of air in the cylinder at the first end of the disposable syringe and then push the plunger into the cylinder until the undesired air is displaced out of the cylinder through the attachment opening in this first end, the finger handle of the plunger constantly being kept in position outside the second opening of the cylinder.
  • the link between the finger handle and the plunger is a conventional plunger rod of e.g. a rigid plastic.
  • the plunger, finger handle and plunger rod in this embodiment together have an extent not exceeding the inner longitudinal extent of the cylinder and as the finger handle in the first position is located at least a distance outside the second opening of the cylinder to thereby allow the user with his fingers to grip the finger handle to manipulate the plunger, the plunger will in the first position be located in the cylinder at a distance from the first end of the cylinder to thereby leave a volume of residual air encapsulated in the cylinder between the plunger and the first end of the cylinder.
  • this residual air can easily be expelled in a known manner by, as mentioned above, ventilating the disposable syringe with a number of reciprocating plunger travels until the residual air has been substituted by the wanted volume of injection fluid which typically fills the volume between the plunger and the first end of the disposable syringe, the plunder abutting on or being located near the stop in the filled state of the disposable syringe.
  • the link between the finger handle and the plunger can be a plunger rod having a first section located nearest the finger handle and a second section located in tandem of the first section farther from the finger handle, the free end of this second section being designed with a collar which together with the second section of the plunger rod can extend into a chamber on the plunger.
  • This chamber can preferably be designed with a first base located nearest the first end of the cylinder and an opposite second base having an opening through which the second section of the plunger rod with the collar is extending.
  • the plunger rod can at the transition between the first and second section of the plunger rod have a pressure face facing the plunger and hitting the second base of the chamber and serving for affecting the plunger with the necessary compressive force when the plunger is to be taken from the first position to the second position which e.g. is the case when the content of the disposable syringe is to be injected at a designated place of injection.
  • the second section of the plunger rod and the collar can together have an extent that substantially corresponds to or exceeds the longitudinal extent of the chamber.
  • the collar on the second section of the plunger rod will abut on and hit the first base of the chamber in the second position of the plunger to thereby transmit the compressive force necessary for injection to the plunger.
  • the collar on the free end of the second section of the plunger rod can especially advantageously be designed as a pointed barb where the ratio between the collar diameter and the diameter of the opening in the second base of the plunger chamber is chosen so that the barb easily can be mounted in the plunger chamber through this opening when the syringe is prepared for use and cannot be forced out of the opening of the plunger chamber when the syringe is in use or has been used.
  • the plunger rod and the cylinder can if required be supplied separately.
  • the chamber can expediently be designed as a hollow rubber plug lubricated with silicone along the outer periphery to allow the plunger to be displaced in the cylinder easily and unobstructedly.
  • the chamber can internally be provided with a constriction which advantageously can divide the chamber into a first sectional chamber facing the first base and a second sectional chamber facing the second base, the barb being located in the second sectional chamber when the disposable syringe is being filled while the plunger is' kept in its first position.
  • the constriction will allow the pointed barb on the second section of the plunger rod to freely pass from the second sectional chamber into the first sectional chamber to possibly hit the first base of the chamber.
  • the constriction will advantageously prevent the barb from freely returning to the first sectional chamber .
  • the constriction in the plunger chamber can be located so that the entire longitudinal extent of the part of the second section of the plunger rod projecting from the chamber, after the barb during emptying of the disposable syringe being introduced into the first sectional chamber, and the first section of the plunger rod together are so much smaller than the distance between the stop of the cylinder and the second opening of the cylinder that the finger handle cannot project from the cylinder in the second position.
  • the side of the finger handle facing the second opening of the cylinder can be designed with locking means for locking the finger handle in cooperating locking means designed on the stop.
  • locking means can e.g. be a circumferential barb designed on the finger handle and which can be hooked together with recess designed on the stop or vice versa.
  • the link between the finger handle and the plunger can comprise a rigid first section located nearest the finger handle and a second section located in tandem of this first section, oppositely and farther from the finger handle, said second section having an extended state in which it can transmit drawing forces but not compressive forces, and a collapsed state in which it can transmit compressive forces but not drawing forces.
  • the second section can be a strip or a wire of a flexible material, such as a flexible plastic as e.g. polyethylene or polypropylene, the material only being chosen so that it has a tensile strength sufficiently great to resist the drawing force required to be able to fill the disposable syringe.
  • the size of the necessary drawing force will depend on the dimensions of the disposable syringe and the volume of injection fluid to be filled into the disposable syringe.
  • the plunger When the disposable syringe is to be emptied and the injection fluid e.g. injected into an individual, the plunger must be affected with a compressive force that will force the plunger from the first position to the second position. During this, the flexible material between the pressure face on the second section of the plunger rod and the plunger is folded and compressed. As the finger handle now will be completely received in the cylinder, the disposable syringe cannot be reused.
  • the second section consists of a strip or a wire of a rigid material with a number of folding or rupture lines designed along the strip or wire
  • the strip and the wire will collapse at the weakened zones of the folding or rupture lines, and the strip or wire will be folded and compressed in a manner similar to the one described above for a strip or wire of a flexible material .
  • the needle and the disposable syringe can be manufactured as an integrated unit.
  • the needle will be premounted at the first end of the disposable syringe at the attachment opening for a needle.
  • a loose needle can be mounted on the nozzle of the disposable syringe in such a way that it subsequently cannot be demounted without thereby destroying either the needle and/or the disposable syringe.
  • the nozzle and the needle can be provided with known locking means, the mutual engagement of which subsequently cannot be broken.
  • Such locking means are known from e.g. a LUER-LOCK syringe nozzle.
  • the needle will preliminarily be capped by a detachable needle cap.
  • the cap can have a diameter equal to or smaller than the internal diameter of the cylinder, said section simultaneously having a length at least as great as the distance between the finger handle and the second opening of the cylinder in the second position of the plunger.
  • a needle cap designed in such a way can advantageously be utilised for assisting in the displacement of the plunger from the first position to the second position. This can especially advantageously be done when a recess or pin is designed in the free end face of the finger handle and when a complementary pin or recess is designed in the free end face on the needle cap at said section.
  • Recess or tap can advantageously engage with each other whereby the needle cap can be used in tandem of the plunger rod so that the finger handle can be pushed down in the cylinder in an especially easy manner.
  • the hollowness of the needle cap can receive a pin designed on the finger handle or the plunger rod.
  • the finger handle can advantageously have an extended area which is connected to the finger handle via a rupture line or weakened zone.
  • Such an area can merely be one or more projecting flaps or tabs but can also be a circumferential collar on the finger handle.
  • the rupture line When a finger handle designed in such a way hits the edge around the second opening of the cylinder, the rupture line will be affected to such an extent that the extended area will be completely or partly broken off or everted, this area being at least partly retained by the second opening or internal diameter of the cylinder and during this be everted in the direction opposite the travel of the plunger. In this way, the area will serve as sealing and/or barbs to counter the plunger from being drawn out of the cylinder after use.
  • Another way to prevent the finger handle from unintentionally being received in the cylinder consists in a finger handle cover being part of the finger handle, said cover preliminarily covering the finger handle in the first position of the disposable syringe and being removed and discarded when the content of the disposable syringe is to be injected into an individual .
  • the method comprises that the disposable syringe is being filled by the needlepoint being placed in an injection fluid in a known manner, that the injection fluid is being drawn into the cylinder by means of at least one possibly reciprocating manipulation of the finger handle and thereby the plunger.
  • the finger handle is actuated in a simple way with a compressive force until the finger handle is under the second opening of the cylinder.
  • This operation can especially easily be done when a cover detachably mounted on the needle is fitted in tandem of the finger handle and used to press the finger handle into the cylinder until this handle is completely received in the cylinder.
  • Fig. 1 is a longitudinal cross section through a first embodiment of a disposable syringe according to the invention and a vial shown in perspective,
  • Fig. 2 is the view in fig. 1 in a first filling step
  • Fig. 3 is the view in fig. 1 in a first ventilation step
  • Fig. 4 is the view in fig. 1 in a second filling step
  • Fig. 5 is the view in fig. 1 in a second ventilation step
  • Fig. 6 is the view in fig. 1 in a third filling step
  • Fig. 7 is the view in fig. 1 during emptying
  • Fig. 8 is the view in fig. 1 in completely empty state
  • Fig. 9 is the view in fig. 1 in a second position in which the disposable syringe cannot be reused
  • Fig. 10 is a longitudinal cross section through a second embodiment of a disposable syringe according to the invention and a vial shown in perspective,
  • Fig. 11 is the view in fig. 10 in filled state
  • Fig. 12 is the view in fig. 10 in a first emptying step
  • Fig. 13 is the view in fig. 10 in which the disposable syringe has been emptied
  • Fig. 14 is a view of the second position of the plunger in which the disposable syringe cannot be reused
  • Fig. 15 is a longitudinal cross section through a third embodiment of a disposable syringe according to the invention and a vial shown in perspective,
  • Fig. 16 is the view in fig. 15 in filled state
  • Fig. 17 is the view in fig. 15 in a first emptying step
  • Fig. 18 is the view in fig. 15 in which the disposable syringe has been emptied
  • Fig. 19 is a view of the disposable syringe with the plunger in its second position in which the disposable syringe cannot be reused
  • Fig. 20 shows the second position of a modification of the second embodiment of the disposable syringe according to the present invention
  • Fig. 21 is the view in fig. 20 but with the finger handle locked together with the stop
  • Fig. 22 is a longitudinal cross section through a fourth embodiment of a disposable syringe according to the invention and a vial shown in perspective,
  • Fig. 23 is the view in fig. 22 in filled state
  • Fig. 24 is the view in fig. 22 in a first emptying step
  • Fig. 25 is the view in fig. 22 in a second emptying step, ly-uo- uuz
  • Fig. 26 is the view in fig. 22 in emptied state with the plunger in its second position in which the disposable syringe cannot be reused.
  • Fig. 27 shows a first emptying position of the second embodiment in which the finger handle has a pair of flaps designed with rupture zones for preventing the plunger from unintentionally being received in the cylinder
  • Fig. 28 is the view in fig. 27 but in a second emptying position in which the flaps are abutting on the edge around the second opening of the cylinder,
  • Fig. 29 is the view in fig. 27 in which the flaps have been broken off and the plunger is in its first position
  • Fig. 30 is a longitudinal cross section of an additional modification of the embodiment in figs. 1-9 in a first position in which the modification is arranged to be used with a conventional needle, and
  • Fig. 31 is the view in fig. 30 in the second position.
  • Figs. 1-9 show a first embodiment of a disposable syringe according to the invention in a number of different steps of a filling and an emptying of the disposable syringe.
  • the disposable syringe 1 for injecting a fluid into an individual has a tubular cylinder 2 having an attachment opening 3 for a needle 24 at the first end 16 and a second opening 4 at the opposite second end, a plunger 5 displaceable between a first position and a second position and located in the cylinder 2, a finger handle 6 which is connected to the plunger 5 and is outside the second opening 4 of the cylinder 2 in the first position of the plunger 5 and inside the second opening 4 of the cylinder 2 in the second position of the plunger 5.
  • the cylinder has an internal stop 7 restricting the travel of the plunger 5 from the second position to the first position, and a collar 8 designed externally at the second opening 8, said collar serving as abutment to fingers when the disposable syringe 1 is to be emptied.
  • the stop 7 has a small clearance to the plunger rod 14 to allow air in the cavity 15 between the plunger 5 and the stop 7 to pass to the venting chamber in the direction of the arrows when the plunger 5 is drawn in direction out of the cylinder 2.
  • the stop 7 also serves for preventing the plunger 5 from being drawn completely out of the cylinder 2.
  • the needle 24 is here shown premounted and covered by a needle cap 9 which is removed when the injection fluid 10 in the vial 11 is to be drawn into the disposable syringe 1.
  • the plunger 5 has two lips 12,13 between which an O-ring optionally can be fitted for ensuring that injection fluid 10 does not pass through from the fluid chamber 17 to the venting chamber 18.
  • the needle cap 9 has been removed from the needle 24 which subsequently has been passed through the rubber plug 19 of the vial 11 down into the injection fluid 10.
  • the plunger 5 is displaced towards the first position of the plunger 5 and is abutting on the stop 7, a volume of injection fluid 20 having been drawn into the fluid chamber 17 during this.
  • the fluid chamber 17 is only partly filled and therefore contains a volume of residual air 21 which, as shown in fig. 3, is forced out as the disposable syringe being turned upside down and residual air 21 being displaced into the vial 11 by guiding the plunger 5 in the direction of the arrow whereby residual air 21 is transferred to the vial 11.
  • the cavities 15 is filled with air from the venting chamber 18 as shown with the arrows in the figure.
  • the needle 24 is drawn out of the vial 11 and the needle cap 9 is placed with its cap point 22 in a recess 23 designed on the finger handle 6.
  • the needle cap 9 is pressed in the direction shown with the arrow in figs . 7 and 8 with a compressive force towards the finger handle 6 whereby the injection fluid 20 is injected into an individual (not shown) or other receptacle (not shown), such as e.g. a drip tube (not shown) or another vial (not shown) .
  • the plunger 5 is abutting on the first end 16 of the cylinder 2 in its final position in which the disposable syringe 1 has been emptied of injection fluid 20.
  • the cap point 22 of the needle cap 9 is removed from the recess 23 and placed over the needle 24 again as shown in fig. 9.
  • Fig. 10 shows a second embodiment 25 of a disposable syringe according to the invention. This embodiment corresponds to the first embodiment 1 described in figs. 1-9 but the plunger and the plunger rod have been modified.
  • the plunger rod 26 has a first section 27 located nearest the finger handle 6 and a second section 28 of a reduced cross section and located in tandem of the first section 27 farther from the finger handle 6.
  • the first section 27 has a pressure face 30 facing the plunger 29, at the transition between the first section 27 and the second section 28, and the free end of the second section 28 has a pointed barb 31.
  • the plunger 29 is designed as a chamber 29 having a first base 32 located nearest the first end 16 of the cylinder 2 and an opposite second base 33 with an opening 34 through which the second section 27 of the plunger rod 26 is extending into the chamber 29. As shown in fig. 10, the barb 31 is abutting on the second base 33 of the chamber 29 in the first position of the plunger .
  • the needle cap 9 is removed and the needle 24 guided into the injection fluid 10 via the rubber plug 19 of the vial 11.
  • the injection fluid 10 is transferred to the fluid chamber 17, as the plunger 29 is being drawn in the direction of the arrow out of the cylinder 2, as air present in the fluid chamber prior to filling of the disposable syringe 25 is passing out through the space between the stop 7 and the plunger rod 26.
  • the barb 31 is gripping the second base 33 of the chamber 29 until the plunger 29 is abutting on the stop 7 and the fluid chamber 17 is full.
  • the cap point 22 of the needle cap 9 is mounted in a recess 23 in the finger handle 6 as shown in fig. 12.
  • the plunger rod 26 is freely returned to a position in which the barb 31, as shown in fig. 12, is abutting on the first base 32 of the chamber 29.
  • the plunger rod 26 is returned to a not shown position in which the pressure face 30 is abutting on the second base 33 of the chamber 29.
  • the chamber 29 is advantageously designed as a hollow rubber plug having a coefficient of friction in relation to the cylinder of a size that causes the plunger 29 not to be able to return by itself in a direction out of the cylinder 2.
  • the opening 34 in the chamber is tight around the first section 28 of the plunger rod 26 so that the plunger 29 is secured against the finger handle 6 being caught through the second opening 16 of the cylinder 2.
  • the injection fluid 20 is injected or forced out of the fluid chamber 17 through the needle 24, the needle cap 9 being pressed against the finger handle 6 with a compressive force in the direction indicated by the arrow in fig. 13 until the plunger 29 reaches its second position in which the finger handle 6 is fully received in the cylinder 2.
  • the needle cap 9 is removed from, the recess 23 to again be fitted as protection cap 9 over the needle 24 so that the disposable syringe 25 can be discarded without risk of reutilization.
  • the stop 7 is also serving to prevent the plunger 5 from being drawn completely out of the cylinder 2.
  • the third embodiment in figs. 15-19 of a disposable syringe according to the present invention is a modification of the second embodiment described in figs. 10-14.
  • the chamber 29 has a constriction 36 at a distance from the first base 32 and the second base 33 respectively.
  • the constriction 36 is dividing the chamber 29 into a first sectional chamber 37 and a second sectional chamber 38 in which the barb 31 is located prior to use.
  • the injection fluid 10 is transferred to the fluid chamber 17 as described with reference to fig. 11 and shown in fig. 16, the plunger 29 being drawn in the direction of the arrow out of the cylinder 2, and the barb 31 gripping the second base 33 of the chamber 29 during this until the plunger 29 is abutting on the stop 7.
  • the syringe is emptied as shown in fig. 17 by at first mounting the needle point 22 of the needle cap 9 in a recess 23 in the finger handle 6 and subsequently affecting the needle cap 9 with a compressive force in the direction indicated by the arrow in the figure, the barb 31 passing form the second sectional chamber 38 to the first sectional chamber 37 through the constriction 36 during this.
  • the pressure face 30 is abutting on the second base 33 of the plunger 29 and the barb 29 on the first base 32 of the plunger 29 during the emptying process.
  • the pressure face 30 it is however only necessary for the pressure face 30 to abut on the second base 33 of the plunger 29 or for the barb 29 to abut on the first base 32 of the plunger 29.
  • Figs. 20 and 21 shown a modification 39 of the second embodiment in figs. 10-14 of a disposable syringe according to the present invention.
  • the finger handle 6 has a circumferential barb 40 at the side of the finger handle 6 facing the second opening 4 of the cylinder 2, and the stop 7 has a cooperating barb 41.
  • the needle cap 9 on the finger handle 6 is displaced with a compressive force in the direction indicated by the arrow in fig. 20, the barbs 40 are made to engage the barbs 41 in a locking manner.
  • the needle cap 9 is again mounted on the needle 4 and the disposable syringe 39 cannot be reused.
  • Figs. 22-26 show a fourth embodiment 42 of a disposable syringe according to the invention. This embodiment is a modification of the previously described embodiments and like parts are therefore similarly referenced.
  • the disposable syringe 42 has a cylinder 2 with a first opening 3, with an attachment opening 3 for a needle 24 which preliminarily is covered by a needle cap 9, and a second opening 4 for receiving a plunger 5, which via a plunger rod 26 having a first section 27 and a second section 28 is connected to a finger handle 6 in which a recess 23 is designed.
  • the cylinder 2 has an internally designed stop 7 for restricting the travel of the plunger 5 between first and second position and an externally designed collar 8 for forming abutment to fingers during emptying of the disposable syringe.
  • the second section 28 of the plunger rod 26 has a total number of six folding lines 43 in the example shown in figs. 22-26.
  • the folding lines 43 in the first section 28 can withstand the drawing force necessary of the injection fluid 10 to be transferred to the fluid chamber 17 via the needle 24 placed in the vial 11 when the finger handle 6 is drawn in the direction indicated by the arrow in fig. 23 until the plunger 5 is abutting on the stop 7 and the fluid chamber 17 has been filled with a volume of injection fluid 20.
  • the cap point 22 of the needle cap 9 is fitted in the recess 23 on the finger handle 6 and by means of a compressive force on the needle cap 9 in the direction indicated by the arrow in fig. 24, the pressure face 30 of the plunger rod 26 is guided in direction towards the plunger 5, the folding lines 43 making the second section 28 of the plunger rod 26 collapse during this.
  • fig. 25 is seen an initial emptying step in which the collapsed second section 28 is compressed against the plunger 5 and displaced past the stop 7 at the same time as the injection fluid 20 is displaced out of the disposable syringe 42 by means of the plunger 5 until the position in fig. 25 has been reached.
  • the finger handle 6 cannot again be brought to a position in which it is outside the second opening 4 of the cylinder 2.
  • the needle cap 9 is removed from the internal diameter of the cylinder 2 and placed over the needle 24 after which the disposable syringe 40 is discarded without possibility of being able to be reused.
  • Fig. 27 shows the second embodiment 25 in empty state with the cap point 22 of the needle cap 9 fitted in the recess 23 of the finger handle 6 where the finger handle 6 in addition has a pair of flaps 44 which is connected to the finger handle 6 via rupture zones 45.
  • the flaps 44 ensure that the finger handle 6 not unintentionally can be received in the cylinder 2 when the disposable syringe e.g. is stored in its packaging.
  • the flaps 44 are cut or broken off at the rupture zones 45 during the continued displacement of the plunger 5 towards its second position in direction towards the first end 3 of the cylinder 2 until the finger handle is completely received in the cylinder 2.
  • stop 7 is serving to prevent the plunger 5 from being drawn completely out of the cylinder 2.
  • Fig. 30 shows a modification of the embodiment in figs. 1-9 arranged to be able to be used with a conventional needle 46 which is covered by a conventional, mainly conic needle cap 47 having a diameter at least along a section that is equal to or smaller than the internal diameter of the cylinder 2.
  • a LUER-LOCK 49 is designed and is arranged to be connected with the needle so that it subsequently cannot be demounted again.
  • a depression 48 is designed that, as shown in fig. 31, is serving for receiving the needle cap 47 when the plunger 5 is displaced towards the second position incidentally in the same manner as described for the rest of the embodiments shown and described in figs. 1-29.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne une seringue jetable (1, 25, 35, 42) permettant d'injecter un liquide (10), la seringue jetable comprenant un cylindre tubulaire (2) présentant une ouverture (3) de fixation sur la première extrémité (16) destinée à recevoir une aiguille (24, 46) et une seconde ouverture (4) sur la seconde extrémité opposée, un piston (5, 29) pouvant se déplacer entre une première position et une seconde position, et étant situé dans le cylindre (2), une liaison (14, 26), reliant le piston (5, 29) et la poignée permettant le positionnement des doigts (6), située à l'extérieur de la seconde ouverture (4) du cylindre (2) lorsque le piston (5, 29) est dans la première position et à l'intérieur de la seconde ouverture (4) du cylindre (2) lorsque le piston (5, 29) est dans la seconde position. La poignée permettant le positionnement des doigts est complètement comprise dans le cylindre, étant donné qu'elle peut être déplacée, au moyen, par exemple, du capuchon d'aiguille (9, 47) recouvrant l'aiguille avant utilisation, vers la seconde position jusqu'à ce qu'il ne soit plus possible de saisir la poignée permettant le positionnement des doigts. Le capuchon d'aiguille peut ultérieurement être remonté sur l'aiguille et la seringue jetable rendue non réutilisable peut être mise au rebut.
PCT/DK2002/000131 2001-02-28 2002-02-27 Seringue jetable WO2002076542A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200100330 2001-02-28
DKPA200100330 2001-02-28

Publications (1)

Publication Number Publication Date
WO2002076542A1 true WO2002076542A1 (fr) 2002-10-03

Family

ID=8160320

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2002/000131 WO2002076542A1 (fr) 2001-02-28 2002-02-27 Seringue jetable

Country Status (1)

Country Link
WO (1) WO2002076542A1 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005123163A1 (fr) * 2004-06-10 2005-12-29 Safety Syringes, Inc. Melange et delivrance de diluants par systeme de delivrance passive
WO2007122193A1 (fr) * 2006-04-21 2007-11-01 Novo Nordisk A/S dispositif d'injection PAR jet À deux STADES
US8105292B2 (en) 2008-02-11 2012-01-31 Safety Syringes, Inc. Reconstitution means for safety device
US8608684B2 (en) 2003-11-27 2013-12-17 Novo Nordisk A/S Impulse chamber for jet delivery device
US9044378B2 (en) 2007-05-31 2015-06-02 Safety Syringes, Inc. Anti-needle stick safety device or system for use with drugs requiring reconstitution
WO2021081643A1 (fr) * 2019-10-28 2021-05-06 Liquimedlock Seringue

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5017187A (en) * 1990-05-04 1991-05-21 Sullivan Robert J Self retracting hypodermic syringe
WO1997007839A1 (fr) * 1995-08-22 1997-03-06 Mdc Investment Holdings, Inc. Aiguille retractable pre-remplie pour ampoules d'injection
WO1997035632A1 (fr) * 1996-03-27 1997-10-02 Science Incorporated Ensemble seringue pour melange et injection
EP0914837A2 (fr) * 1991-12-23 1999-05-12 PRESSLY, William B. S. Seringue de sécurité
US6010486A (en) * 1998-12-18 2000-01-04 Becton Dickinson And Company Retracting needle syringe
WO2000029051A1 (fr) * 1998-11-13 2000-05-25 B.F. Elettromeccanica S.R.L. Seringue jetable pour melanger automatiquement un premier et un second constituants
US6179812B1 (en) * 1989-07-11 2001-01-30 Mdc Investment Holdings, Inc. Retractable needle medical devices
EP1092442A1 (fr) * 1999-10-15 2001-04-18 Becton Dickinson and Company Méthode de fabrication d'une seringue à aiguille escamotable
US6221055B1 (en) * 1998-03-04 2001-04-24 Retractable Technologies, Inc. Retractable dental syringe
US20010004685A1 (en) * 1997-09-30 2001-06-21 Hubert Jansen Lockable safety shield assembly for a prefillable syringe
WO2001066179A1 (fr) * 2000-03-06 2001-09-13 Mdc Investment Holdings, Inc. Seringue hypodermique a aiguille retractable

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6179812B1 (en) * 1989-07-11 2001-01-30 Mdc Investment Holdings, Inc. Retractable needle medical devices
US5017187A (en) * 1990-05-04 1991-05-21 Sullivan Robert J Self retracting hypodermic syringe
EP0914837A2 (fr) * 1991-12-23 1999-05-12 PRESSLY, William B. S. Seringue de sécurité
WO1997007839A1 (fr) * 1995-08-22 1997-03-06 Mdc Investment Holdings, Inc. Aiguille retractable pre-remplie pour ampoules d'injection
WO1997035632A1 (fr) * 1996-03-27 1997-10-02 Science Incorporated Ensemble seringue pour melange et injection
US20010004685A1 (en) * 1997-09-30 2001-06-21 Hubert Jansen Lockable safety shield assembly for a prefillable syringe
US6221055B1 (en) * 1998-03-04 2001-04-24 Retractable Technologies, Inc. Retractable dental syringe
WO2000029051A1 (fr) * 1998-11-13 2000-05-25 B.F. Elettromeccanica S.R.L. Seringue jetable pour melanger automatiquement un premier et un second constituants
US6010486A (en) * 1998-12-18 2000-01-04 Becton Dickinson And Company Retracting needle syringe
EP1092442A1 (fr) * 1999-10-15 2001-04-18 Becton Dickinson and Company Méthode de fabrication d'une seringue à aiguille escamotable
WO2001066179A1 (fr) * 2000-03-06 2001-09-13 Mdc Investment Holdings, Inc. Seringue hypodermique a aiguille retractable

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8608684B2 (en) 2003-11-27 2013-12-17 Novo Nordisk A/S Impulse chamber for jet delivery device
WO2005123163A1 (fr) * 2004-06-10 2005-12-29 Safety Syringes, Inc. Melange et delivrance de diluants par systeme de delivrance passive
US7294119B2 (en) 2004-06-10 2007-11-13 Safety Syringes, Inc. Passive delivery system diluents mixing and delivery
US7981088B2 (en) 2004-06-10 2011-07-19 Safety Syringes, Inc. Passive delivery system diluents mixing and delivery
WO2007122193A1 (fr) * 2006-04-21 2007-11-01 Novo Nordisk A/S dispositif d'injection PAR jet À deux STADES
US9044378B2 (en) 2007-05-31 2015-06-02 Safety Syringes, Inc. Anti-needle stick safety device or system for use with drugs requiring reconstitution
US8105292B2 (en) 2008-02-11 2012-01-31 Safety Syringes, Inc. Reconstitution means for safety device
US8128613B2 (en) 2008-02-11 2012-03-06 Safety Syringes, Inc. Reconstitution means for safety device
US9498581B2 (en) 2008-02-11 2016-11-22 Safety Syringes, Inc. Reconstitution means for safety device
US10702663B2 (en) 2008-02-11 2020-07-07 Safety Syringes, Inc. Reconstitution means for safety device
WO2021081643A1 (fr) * 2019-10-28 2021-05-06 Liquimedlock Seringue

Similar Documents

Publication Publication Date Title
US7601139B2 (en) Spring launched needle safety clip
US9486582B2 (en) Automatic injection device with temporizing means
US5501670A (en) Syringe system providing retraction of needle cannula into disposable cartridge
US6270482B1 (en) Multiple-dose syringe
CN102458536B (zh) 采用凸缘锁防止被动再使用的注射器
KR20050025179A (ko) 안전 주사기
JP2008504928A (ja) 使い捨て注射器
AU2002350451A1 (en) Spring launched needle safety clip
JPH10507935A (ja) 薬剤等の注射針
US20060122561A1 (en) Auto-destructible syringe
MXPA01006743A (es) Jeringa hipodermica con aguja selectivamente retractil.
MXPA01006619A (es) Jeringa hipodermica con una aguja selectivamente retractil.
US6832703B1 (en) Monomer vial breaker
CN106730174A (zh) 注射器组件
KR101497734B1 (ko) 재사용 방지 기구를 포함하는 주사기 조립체
WO2002076542A1 (fr) Seringue jetable
US20080188807A1 (en) Syringe Assembly Having Re-Use Prevention Features
US20230330343A1 (en) Safety syringe with flexible reservoir and method of use
WO2023141680A1 (fr) Dispositifs et procédés pour seringues conçus pour réduire ou éliminer un volume résiduel

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ CZ DE DE DK DK DM DZ EC EE EE ES FI FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP