WO2002055026A2 - Perfluoro sulfonyl halides and related species as polymer support modifiers - Google Patents

Perfluoro sulfonyl halides and related species as polymer support modifiers Download PDF

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Publication number
WO2002055026A2
WO2002055026A2 PCT/US2002/000839 US0200839W WO02055026A2 WO 2002055026 A2 WO2002055026 A2 WO 2002055026A2 US 0200839 W US0200839 W US 0200839W WO 02055026 A2 WO02055026 A2 WO 02055026A2
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WO
WIPO (PCT)
Prior art keywords
group
support
solid
subscript
resin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/000839
Other languages
English (en)
French (fr)
Other versions
WO2002055026A3 (en
Inventor
Christopher Holmes
Yijun Pan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affymax Inc
Original Assignee
Affymax Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US10/466,124 priority Critical patent/US7700524B2/en
Priority to KR10-2003-7009277A priority patent/KR20030078069A/ko
Priority to CA002434570A priority patent/CA2434570A1/en
Priority to HU0303192A priority patent/HUP0303192A2/hu
Priority to MXPA03006228A priority patent/MXPA03006228A/es
Priority to EP02714736A priority patent/EP1352243A4/en
Priority to IL15667702A priority patent/IL156677A0/xx
Priority to AU2002246986A priority patent/AU2002246986B2/en
Priority to BR0206386-7A priority patent/BR0206386A/pt
Priority to JP2002555763A priority patent/JP4349559B2/ja
Application filed by Affymax Inc filed Critical Affymax Inc
Publication of WO2002055026A2 publication Critical patent/WO2002055026A2/en
Publication of WO2002055026A3 publication Critical patent/WO2002055026A3/en
Priority to ZA2003/05099A priority patent/ZA200305099B/en
Anticipated expiration legal-status Critical
Priority to US12/760,840 priority patent/US20110028751A1/en
Ceased legal-status Critical Current

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    • C40—COMBINATORIAL TECHNOLOGY
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    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
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    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/34—Introducing sulfur atoms or sulfur-containing groups
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • B01J2231/4255—Stille-type, i.e. RY + R'3SnR'', in which R is alkenyl, aryl, R' is alkyl and R'' is alkenyl or aryl
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/40—Substitution reactions at carbon centres, e.g. C-C or C-X, i.e. carbon-hetero atom, cross-coupling, C-H activation or ring-opening reactions
    • B01J2231/42—Catalytic cross-coupling, i.e. connection of previously not connected C-atoms or C- and X-atoms without rearrangement
    • B01J2231/4205—C-C cross-coupling, e.g. metal catalyzed or Friedel-Crafts type
    • B01J2231/4261—Heck-type, i.e. RY + C=C, in which R is aryl
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J2231/40—Substitution reactions at carbon centres, e.g. C-C or C-X, i.e. carbon-hetero atom, cross-coupling, C-H activation or ring-opening reactions
    • B01J2231/42—Catalytic cross-coupling, i.e. connection of previously not connected C-atoms or C- and X-atoms without rearrangement
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    • B01J2531/80—Complexes comprising metals of Group VIII as the central metal
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    • B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
    • B01J31/2409—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring with more than one complexing phosphine-P atom
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PCT/US2002/000839 2001-01-12 2002-01-11 Perfluoro sulfonyl halides and related species as polymer support modifiers Ceased WO2002055026A2 (en)

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BR0206386-7A BR0206386A (pt) 2001-01-12 2002-01-11 Ativador ligado a suporte, suporte ativado, kit, biblioteca de alvos ativados pelo suporte, suporte fortemente ácido, suporte sililador, método de fixar covalentemente um nucleófilo a um composto apresentando um grupo hidróxi ou uma cetona enolizável, e, reagente ligador
CA002434570A CA2434570A1 (en) 2001-01-12 2002-01-11 Perfluoro sulfonyl halides and related species as polymer support modifiers
HU0303192A HUP0303192A2 (hu) 2001-01-12 2002-01-11 Perfluor-szulfonil-halogenidek és hasonló vegyületek polimerből készült hordozók módosítására
MXPA03006228A MXPA03006228A (es) 2001-01-12 2002-01-11 Haluros de perfluoro sulfonilo y especies relacionadas como modificadores de soporte de polimero.
EP02714736A EP1352243A4 (en) 2001-01-12 2002-01-11 PERFLUOR SULFONYLHALOGENIDES AND RELATED SPECIES AS MODIFICATORS POLYMERIC SUPPORTS
IL15667702A IL156677A0 (en) 2001-01-12 2002-01-11 Perfluoro sulfonyl halides and related species as polymer support modifiers
AU2002246986A AU2002246986B2 (en) 2001-01-12 2002-01-11 Perfluoro sulfonyl halides and related species as polymer support modifiers
US10/466,124 US7700524B2 (en) 2001-01-12 2002-01-11 Perfluoro sulfonyl halides and related species as polymer support modifiers
KR10-2003-7009277A KR20030078069A (ko) 2001-01-12 2002-01-11 중합체 지지체 개질제로서의 퍼플루오로술포닐 할라이드및 관련 화합물
JP2002555763A JP4349559B2 (ja) 2001-01-12 2002-01-11 ポリマー支持体変性剤としてのハロゲン化パーフルオロスルホニルおよび関連する化学種
ZA2003/05099A ZA200305099B (en) 2001-01-12 2003-06-30 Perfluoro sulfonyl halides and related species as polymer support modifiers
US12/760,840 US20110028751A1 (en) 2001-01-12 2010-04-15 Perfluoro sulfonyl halides and related species as polymer support modifiers

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EP1491888A4 (en) * 2002-04-03 2006-05-03 Mitsubishi Rayon Co GEL WITH FIXED BIOSUBSTANCE AND GEL USING MICROARRAY
US7976824B2 (en) 2003-07-31 2011-07-12 Ge Healthcare Limited Production of 2-18F-2-deoxy-D-glucose via solid-phase synthesis

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RU2380685C1 (ru) * 2008-11-07 2010-01-27 Шлюмберже Текнолоджи Б.В. Эталонный материал с порами контролируемого размера и формы и блок из фрагментов эталонного материала с порами контролируемого размера и формы
WO2012018709A2 (en) * 2010-08-06 2012-02-09 Arkema Inc. Superacid functional compounds
EP3142709B1 (en) * 2014-05-15 2025-07-30 Mayo Foundation for Medical Education and Research Synthesis sytem comprising a solution target for cyclotron production of radiometals and associated method
JP6912576B2 (ja) * 2016-12-30 2021-08-04 ダウ グローバル テクノロジーズ エルエルシー 促進剤および酸化防止剤を含む樹脂
CN116445941A (zh) * 2023-04-28 2023-07-18 湖南法恩莱特新能源科技有限公司 含氟磺酸酯的制备方法及其电解液和电化学装置
CN116554386B (zh) * 2023-07-07 2023-09-29 国家电投集团氢能科技发展有限公司 全氟磺酰氟树脂的酯化方法和全氟磺酸树脂的制备方法
CN120329653B (zh) * 2025-05-19 2025-11-25 揭阳市恭发塑胶有限公司 一种安全抗菌pp材料及制备方法

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EP1491888A4 (en) * 2002-04-03 2006-05-03 Mitsubishi Rayon Co GEL WITH FIXED BIOSUBSTANCE AND GEL USING MICROARRAY
US7976824B2 (en) 2003-07-31 2011-07-12 Ge Healthcare Limited Production of 2-18F-2-deoxy-D-glucose via solid-phase synthesis

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CA2434570A1 (en) 2002-07-18
HUP0303192A2 (hu) 2003-12-29
CN1524181A (zh) 2004-08-25
WO2002055026A3 (en) 2002-11-14
KR20030078069A (ko) 2003-10-04
RU2003121311A (ru) 2005-02-27
CN100480701C (zh) 2009-04-22
MXPA03006228A (es) 2004-12-06
IL156677A0 (en) 2004-01-04
ZA200305099B (en) 2005-01-26
EP1352243A2 (en) 2003-10-15
US20030124612A1 (en) 2003-07-03
BR0206386A (pt) 2005-04-26
RU2291146C2 (ru) 2007-01-10
EP1352243A4 (en) 2008-07-02
JP4349559B2 (ja) 2009-10-21
US20040106151A1 (en) 2004-06-03
JP2005501798A (ja) 2005-01-20

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