WO2002053561A1 - Excitatory amino acid receptor antagonists - Google Patents

Excitatory amino acid receptor antagonists Download PDF

Info

Publication number
WO2002053561A1
WO2002053561A1 PCT/US2001/044715 US0144715W WO02053561A1 WO 2002053561 A1 WO2002053561 A1 WO 2002053561A1 US 0144715 W US0144715 W US 0144715W WO 02053561 A1 WO02053561 A1 WO 02053561A1
Authority
WO
WIPO (PCT)
Prior art keywords
compound
pharmaceutically acceptable
alkyl
acceptable salt
acid
Prior art date
Application number
PCT/US2001/044715
Other languages
English (en)
French (fr)
Inventor
Vien Van Khau
Michael Edward Letourneau
Michael John Martinelli
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to MXPA03005981A priority Critical patent/MXPA03005981A/es
Priority to EA200300770A priority patent/EA200300770A1/ru
Priority to NZ525821A priority patent/NZ525821A/en
Priority to US10/450,458 priority patent/US20040082606A1/en
Priority to IL15613801A priority patent/IL156138A0/xx
Priority to CA002431545A priority patent/CA2431545A1/en
Priority to SK824-2003A priority patent/SK8242003A3/sk
Priority to KR10-2003-7008977A priority patent/KR20030066797A/ko
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Priority to DZ013460A priority patent/DZ3460A1/fr
Priority to JP2002554680A priority patent/JP2004520335A/ja
Priority to EP01995980A priority patent/EP1351955A1/en
Priority to BR0116672-7A priority patent/BR0116672A/pt
Priority to HU0302528A priority patent/HUP0302528A2/hu
Priority to PL01361934A priority patent/PL361934A1/xx
Publication of WO2002053561A1 publication Critical patent/WO2002053561A1/en
Priority to NO20032973A priority patent/NO20032973D0/no
Priority to HR20030544A priority patent/HRP20030544A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
PCT/US2001/044715 2001-01-05 2001-12-20 Excitatory amino acid receptor antagonists WO2002053561A1 (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
DZ013460A DZ3460A1 (fr) 2001-01-05 2001-12-20 Antagonistes du recepteur d'acide amine excitateur
EA200300770A EA200300770A1 (ru) 2001-01-05 2001-12-20 Антагонисты рецепторов возбуждающей аминокислоты
JP2002554680A JP2004520335A (ja) 2001-01-05 2001-12-20 興奮性アミノ酸レセプターアンタゴニスト
IL15613801A IL156138A0 (en) 2001-01-05 2001-12-20 Excitatory amino acid receptor antagonists
CA002431545A CA2431545A1 (en) 2001-01-05 2001-12-20 Excitatory amino acid receptor antagonists
SK824-2003A SK8242003A3 (en) 2001-01-05 2001-12-20 Excitatory amino acid receptor antagonists
KR10-2003-7008977A KR20030066797A (ko) 2001-01-05 2001-12-20 흥분성 아미노산 수용체 길항제
MXPA03005981A MXPA03005981A (es) 2001-01-05 2001-12-20 Antagonistas de receptores de aminoacidos excitatorios.
NZ525821A NZ525821A (en) 2001-01-05 2001-12-20 Excitatory amino acid receptor antagonists used in neurological disorders and neurodegenerative diseases
US10/450,458 US20040082606A1 (en) 2001-12-20 2001-12-20 Excitatory amino acid receptor antagonists
EP01995980A EP1351955A1 (en) 2001-01-05 2001-12-20 Excitatory amino acid receptor antagonists
BR0116672-7A BR0116672A (pt) 2001-01-05 2001-12-20 Sal farmaceuticamente aceitável de um composto, composto, composição farmacêutica, uso de um sal farmaceuticamente aceitável, e, processo para preparar um composto
HU0302528A HUP0302528A2 (hu) 2001-01-05 2001-12-20 Ingerlő aminosav receptor antagonisták és e vegyületeket tartalmazó gyógyászati készítmények és eljárás a vegyületek előállítására
PL01361934A PL361934A1 (en) 2001-01-05 2001-12-20 Excitatory amino acid receptor antagonists
NO20032973A NO20032973D0 (no) 2001-01-05 2003-06-27 Eksitatoriske aminosyrereseptorantagonister
HR20030544A HRP20030544A2 (en) 2001-01-05 2003-07-03 Excitatory amino acid receptor antagonists

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26001401P 2001-01-05 2001-01-05
US60/260,014 2001-01-05

Publications (1)

Publication Number Publication Date
WO2002053561A1 true WO2002053561A1 (en) 2002-07-11

Family

ID=22987455

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/044715 WO2002053561A1 (en) 2001-01-05 2001-12-20 Excitatory amino acid receptor antagonists

Country Status (23)

Country Link
EP (1) EP1351955A1 (hr)
JP (1) JP2004520335A (hr)
KR (1) KR20030066797A (hr)
CN (1) CN1484642A (hr)
AR (1) AR035679A1 (hr)
BR (1) BR0116672A (hr)
CA (1) CA2431545A1 (hr)
CZ (1) CZ20031856A3 (hr)
DZ (1) DZ3460A1 (hr)
EA (1) EA200300770A1 (hr)
EC (1) ECSP034682A (hr)
HR (1) HRP20030544A2 (hr)
HU (1) HUP0302528A2 (hr)
IL (1) IL156138A0 (hr)
MX (1) MXPA03005981A (hr)
NO (1) NO20032973D0 (hr)
NZ (1) NZ525821A (hr)
PE (1) PE20020792A1 (hr)
PL (1) PL361934A1 (hr)
SK (1) SK8242003A3 (hr)
TW (1) TW591023B (hr)
WO (1) WO2002053561A1 (hr)
ZA (1) ZA200304311B (hr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0590789A1 (en) * 1992-09-03 1994-04-06 Eli Lilly And Company Excitatory amino acid receptor antagonists
WO1999040084A1 (en) * 1998-02-06 1999-08-12 Smithkline Beecham Plc Salts of paroxetine
WO2000061126A2 (en) * 1999-04-09 2000-10-19 Eli Lilly And Company Limited Method of treating neurological disorders with combinations of nitric oxide synthase inhibitors and excitatory amino acid receptor modulators
WO2001001972A2 (en) * 1999-07-06 2001-01-11 Eli Lilly And Company SELECTIVE iGluR5 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF MIGRAINE

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0590789A1 (en) * 1992-09-03 1994-04-06 Eli Lilly And Company Excitatory amino acid receptor antagonists
WO1999040084A1 (en) * 1998-02-06 1999-08-12 Smithkline Beecham Plc Salts of paroxetine
WO2000061126A2 (en) * 1999-04-09 2000-10-19 Eli Lilly And Company Limited Method of treating neurological disorders with combinations of nitric oxide synthase inhibitors and excitatory amino acid receptor modulators
WO2001001972A2 (en) * 1999-07-06 2001-01-11 Eli Lilly And Company SELECTIVE iGluR5 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF MIGRAINE

Also Published As

Publication number Publication date
KR20030066797A (ko) 2003-08-09
PL361934A1 (en) 2004-10-18
SK8242003A3 (en) 2004-01-08
CZ20031856A3 (cs) 2003-09-17
CA2431545A1 (en) 2002-07-11
MXPA03005981A (es) 2003-09-10
IL156138A0 (en) 2003-12-23
JP2004520335A (ja) 2004-07-08
HRP20030544A2 (en) 2004-08-31
ZA200304311B (en) 2004-09-02
PE20020792A1 (es) 2002-09-06
HUP0302528A2 (hu) 2003-11-28
NO20032973L (no) 2003-06-27
ECSP034682A (es) 2003-08-29
BR0116672A (pt) 2003-09-23
TW591023B (en) 2004-06-11
NO20032973D0 (no) 2003-06-27
NZ525821A (en) 2004-07-30
EA200300770A1 (ru) 2003-10-30
DZ3460A1 (fr) 2002-07-11
AR035679A1 (es) 2004-06-23
EP1351955A1 (en) 2003-10-15
CN1484642A (zh) 2004-03-24

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