WO2002051718A1 - Systeme d'emballage - Google Patents

Systeme d'emballage Download PDF

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Publication number
WO2002051718A1
WO2002051718A1 PCT/GB2001/005622 GB0105622W WO02051718A1 WO 2002051718 A1 WO2002051718 A1 WO 2002051718A1 GB 0105622 W GB0105622 W GB 0105622W WO 02051718 A1 WO02051718 A1 WO 02051718A1
Authority
WO
WIPO (PCT)
Prior art keywords
packaging system
chamber
frangible member
tampon
crimping
Prior art date
Application number
PCT/GB2001/005622
Other languages
English (en)
Inventor
Lisa Jayne Perry
Original Assignee
Accantia Holdings Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0031655A external-priority patent/GB0031655D0/en
Priority claimed from GB0100382A external-priority patent/GB0100382D0/en
Application filed by Accantia Holdings Limited filed Critical Accantia Holdings Limited
Priority to AU2002216210A priority Critical patent/AU2002216210B2/en
Priority to CA002430490A priority patent/CA2430490A1/fr
Priority to EP01272080A priority patent/EP1351866A1/fr
Priority to GB0313397A priority patent/GB2386361B/en
Priority to JP2002552827A priority patent/JP2004525823A/ja
Priority to US10/250,628 priority patent/US20040112769A1/en
Publication of WO2002051718A1 publication Critical patent/WO2002051718A1/fr
Priority to NO20032764A priority patent/NO20032764L/no

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/22—Details
    • B65D77/24—Inserts or accessories added or incorporated during filling of containers
    • B65D77/245—Utensils for removing the contents from the package, e.g. spoons, forks, spatulas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3261—Flexible containers having several compartments
    • B65D81/3266—Flexible containers having several compartments separated by a common rupturable seal, a clip or other removable fastening device

Definitions

  • the present invention relates to a novel packaging system.
  • the invention relates to a packaging system which is adapted to separate house components which may subsequently be mixed.
  • yoghurts are often presented in a carton with a separate fruit chamber so that the user can mix the fruit into the yoghurt together in desired quantities.
  • products are available in the form of a "dip", for example, bread sticks with a cheese dip or nachos with a spicy dip, and many others.
  • Such products like yoghurts, comprise a plastics member which comprises two chambers with a removable, usually foil, lid.
  • the invention relates to such systems comprising means for applying medicaments and/or lubricants.
  • the invention is especially useful in applying medicaments or lubricants to absorbent articles, e.g. sanitary articles or cotton buds, etc.
  • lubrication consists of low-friction cover nets, meshes and webs and other perforate layers constructed to be capable of deforming resiliently, and permitting the passage of bodily fluids.
  • US Patent No 4,428,747 attempts to overcome this problem with a blister package for holding, e.g. a sanitary tampon, which includes a trough which is adapted to act as a lubricant reservoir.
  • the reservoir is provided with a removable cover.
  • the trough renders the packaging bulky, and the complicated construction is difficult and expensive to manufacture.
  • the design requires that the tampon be removed and dipped into the lubricant.
  • the system cannot easily be incorporated in an integral tampon applicator.
  • a packaging system which comprises a first chamber for housing a first material and a second chamber adapted to house a second material, the first and second chambers being separated by a frangible member.
  • frangible membrane in the packaging system of the invention allows the first and second materials to be brought into contact with each other without opening the packaging system.
  • frangible member should be such that, once ruptured, one or more apertures should be created between the first and second chambers, permitting material in the first chamber to be mixed or contacted with material in the second and vice versa.
  • a wide variety of materials may be housed in the first and second chambers. Examples of such materials include, but are not limited to, yoghurts and fruit sauces; polymerisable adhesives and polymer initiators; shampoos and colouring or conditioners, bread sticks and dip, sausages and dips, cake or biscuit bar and cream, chocolate or fudge sauce, e.g. ice-cream, desserts with fruit, chocolate or fudge sauce.
  • the packaging system houses a medical or a sanitary article.
  • an absorbent article packaging system which comprises a first chamber for housing an absorbent article and a second chamber adapted to act as a substrate reservoir, the first and second chambers being separated by a frangible member.
  • sanitaiy articles can be used for absorbent articles, e.g. cotton buds, sanitary articles or medical articles
  • reference herein to sanitaiy articles should be construed as including medical articles and/or cotton buds.
  • Sanitary products include feminine hygiene products, for example sanitary tampons.
  • Medical products include any dressings, including tampons, where it is desirable to, for example, lubricate or medicate a wound contact surface, cavity wound dressings.
  • the system of the invention is especially suited for housing a sanitary tampon, for example a tampon of conventional design with coverstock and removal cord.
  • Suitable materials for the housing include at least one flexible synthetic polymer, such as a thermoplastic, for example a polyester or polyamide (e.g. nylonTM), polypropylene or polyethylene or other conventionally known polymer materials.
  • a thermoplastic for example a polyester or polyamide (e.g. nylonTM), polypropylene or polyethylene or other conventionally known polymer materials.
  • Elastomeric materials may also be used (for example elastomeric polyurethanes) and may be incorporated together with non-elastomeric material of the film, membrane or sheet.
  • Preferred materials for the housing are polyethylene laminates, examples of such laminates include laminates of polyester/polyethylene, polypropylene/polyethylene, nylon/polyethylene and poly(ethyleneterephthalate)/polyethylene.
  • the most preferred laminate is poly(ethyleneterephthalate)/polyethylene (PET/PE) and especially one in which the PE is a peelable PE.
  • the first and second chambers may be formed of the same, similar or different materials, the last-mentioned including at least one rigid synthetic polymer, such as a thermoplastic, for example a polyester or polyamide (e.g. nylonTM), polypropylene or polyethylene, or other polymer materials.
  • a rigid synthetic polymer such as a thermoplastic, for example a polyester or polyamide (e.g. nylonTM), polypropylene or polyethylene, or other polymer materials.
  • the first and second chambers comprise the same material so that, for example, they may be manufactured from a continuous strip of material.
  • the thickness of the walls of the system may vary and may therefore be from 40 to 100 ⁇ m in thickness for each laminate.
  • the thickness of each of the walls may be the same or different.
  • the PE layer is of greater thickness than the PET layer.
  • the PET layer may be from 10 to 20 ⁇ m in thickness, preferably 10 to 15 ⁇ m. A thickness of 12 ⁇ m is most preferred.
  • the PE layer may be from 30 to 80 ⁇ m in thickness, preferably from 35 to 70 ⁇ m and most preferably from 40 to 65 ⁇ m and especially 40 or 50 ⁇ m.
  • a particularly preferred embodiment comprises a first wall comprising a laminate of 12 ⁇ m PET and 50 ⁇ m peelable PE; and second wall of 50 ⁇ m PET and 65 ⁇ m peelable PE.
  • one or both of the walls may be metallised.
  • the substrate reservoir in the sanitary article packaging system will generally be adapted for providing the substrate only or mainly to the external surface of the sanitary article where it will provide the least hindrance to absorption of bodily fluids.
  • An example would include the nose of a catamenial tampon.
  • the frangible member may comprise a frangible membrane.
  • the frangible member may be created by the bonding together of the walls of the chamber. Such bonding may comprise pressure crimping, heat crimping or the use of an adhesive, or any combination of the aforesaid means.
  • a process for the manufacture of a packaging system as hereinbefore described which comprises heat and/or pressure crimping a portion of a strip material to create a first chamber for housing a first material and a second chamber adapted to house a second material, the process of heat and/or pressure crimping creating a frangible member which separates the first and second chambers.
  • step (v) may be optional to include step (v) as part of one of the earlier steps, e.g. step (ii), thus the heat and/or pressure crimping to create the first and second end seals may incorporate cutting step which may be separate, simultaneous or sequential to the sealing step.
  • a preferred temperature of heat/pressure crimping is from 125 to 160°C, preferably 130 to 150°C, most preferably about 140°C.
  • a preferred pressure for heat/pressure sealing is from 10 to 20 psi, preferably 14 psi.
  • the duration of the crimping may vary and may be from 0.5 to 2.0 seconds, preferably 0.5 to 1.5, most preferably 1 second (under laboratory conditions).
  • the depth of the seal for the frangible membrane may vary and may be from 1 to 10 mm, preferably from 2 to 8 mm, more preferably from 2 to 6 mm and most preferably 3 mm.
  • the depth of the seal may be from 2 to 10 mm, more preferably 3 to 8 mm, more preferably 4 to 6 mm and especially 5 mm.
  • a bread stick housed in the first chamber is pushed into the second chamber, eg containing a cheese sauce, breaking the frangible member.
  • the sauce substantially coats the bread stick and either one or both of the chambers may then be opened to facilitate removal of the food item.
  • one or both of the chambers may be squeezed, the pressure may rupture the frangible member allowing the two materials to mix or to allow the coating of, e.g. an applicator tampon (that cannot itself be forced through the membrane).
  • the substrate may comprise a variety of materials, such as medicaments, cosmetics, drugs, hormones, probiotics or lubricants.
  • medicaments include antimicrobial agents, such as triclosan or chlorhexidine; or antifungal agents, such as clotrimazole.
  • Medicaments also includes homeopathic medicines and/or aromatherapy materials.
  • lubricants examples include extracts of sea algae, such as alginates, agar, cararageen; exsudates of plants, such as tragacanth, gum arabic; extracts of plants, such as pectins, starch fractions and derivates, such as dextrins, amylopectins, hydroxyethyl starch; derivates of cellulose, such.
  • fatty substances such as mono, di, triglycerides of higher saturated fatty acids, polyalkylene glycols and other ethoxylated products, such as polyethylene glycol 200-4000, PEG-G-capryl/caprine glyceride; hydrocarbons, such as paraffin oils, vaseline; polymers, such as polyvinyl alcohols, polyvinyl pyrrolidones, polyacrylates; alcohols, such as ethylene glycol, glycerol; emulsifiers, such as alecithin, cholesterin, or derivates of the sorbitan fatty acid esters; silicones; cellulosic polymers, e.g. KY- Jelly (available in the UK from Johnson & Johnson). Mixtures of any of the aforesaid are also intended to be covered.
  • fatty substances such as mono, di, triglycerides of higher saturated fatty acids, polyalkylene glycols and other ethoxylated products, such as polyethylene glycol
  • the frangible member may comprise at least one line of tear, break, fracture or breach, or other points, or at least one other line or region of brittleness, fragility or weakness. Such a member is thus capable of collapsing and/or tearing, breaking, bursting, cracking or snapping or tearing or breaking down under stress.
  • first chamber and/or the second are movable relative to the rest of the packaging system.
  • a tampon housed in the first chamber is pushed into the second chamber, breaking the frangible member.
  • the substrate substantially coats the nose and shoulder of the tampon.
  • the two chambers may then be opened to facilitate removal of the substantially coated tampon.
  • the method of opening may vary depending upon, inter-alia, the method of construction employed for the chambers.
  • the chambers are formed by crimping the edges of the two walls of the chamber such that one wall may simply be peeled away from the other.
  • the chambers, and especially the first chamber may be provided with means to facilitate peeling of the wall.
  • Such facilitation means may comprise a liftable tab at a corner of the chamber or at one end of the chamber.
  • at least a portion of the periphery of the chamber may be perforated or cut away, e.g. notched to allow an end of the chamber to be torn.
  • the facilitation means is provided adjacent the end of the chamber distal to the frangible member.
  • movable includes, for example, “compressible” and “squeezable” relative to the rest of the applicator and/or packaging system.
  • the system may comprise a tampon applicator.
  • a sanitary article packaging system which comprises a first chamber for housing a sanitary article applicator and a second chamber, adapted to act as a substrate reservoir, the first and second chambers being separated by a frangible member.
  • Means may be provided such as a piston or plunger slidable within the housing means to drive the tampon out of the applicator.
  • the system comprises a cylindrical housing such that the membrane is radial to the cylinder.
  • the substrate reservoir preferentially lies at one end of the cylinder.
  • the second reservoir chamber may be provided with an openable end wall.
  • it may simply comprise an open wall with a removable cover.
  • the cover may be a cardboard or plastics cover or may be, a plastics film, e.g. cellophane.
  • the openable end wall is preferentially the wall distal to the membrane.
  • the tampon be fluid-lubricated for application on its removal from the applicator across all or a major proportion of its absorbent surfaces by passage of the entire tampon product through the fluid lubricant.
  • first and second chambers are in the form of two coaxial hollow cylindrical chambers, containers or other receptacles of the same diameter but unequal axial length with a frangible or collapsible intervening wall or barrier, as hereinbefore described.
  • the absorbent sanitary product (a bullet-shaped catamenial tampon) may be housed in the larger chamber, container or other receptacle, which is the housing, with its nose towards and/or against the frangible wall or barrier, and a fluid lubricant may be held in the smaller chamber, container or other receptacle, which is thus the reservoir.
  • first and second chambers may possess different diameters so that one may be slidable within the other.
  • the reservoir may optionally decrease in internal diameter towards end distal to the membrane.
  • it may taper down and/or be domed or have at least one step change in internal diameter.
  • the side walls of the lubricant reservoir may extend beyond the closure membrane, film or sheet in the form of a dome covering the closure membrane. Additionally or alternatively, the membrane may be integral with the side walls and may optionally be domed.
  • an applicator tampon may be used to break the frangible membrane, it is preferred that the reservoir chamber is squeezed causing the material, eg a lubricant to rupture the frangible member and to be squeezed onto the nose of the applicator.
  • the nose of the tampon is coated as it is ejected from the applicator; in addition to the lubrication of the applicator itself.
  • the tampon and/or the applicator may be used in the treatment of certain disorders and may be used as an alternative to a pessary.
  • a vaginal disorder which comprises delivering a medicament, drug, cosmetic, hormone or a probiotic using a sanitary article packaging system as hereinbefore described.
  • disorders include bacterial, microbial, fungal and parasitic infections or related medical disorders or any combination of the foregoing.
  • the packaging system may be provided with a fastening means for releasably securing the packaging in a folding arrangement.
  • the fold may be a C or an S fold or any conventionally used fold. However, preferentially, the fold is a C fold and particularly a fold along the line of the frangible member.
  • the frangible member comprises the crimped walls of the chambers then a natural fold line is produced.
  • the fastening means may be any conventionally known fastening used in connection with, for example, sanitary articles.
  • the fastening means may comprise an area of adhesive applied to a surface of the outer wall of one or both of the chambers.
  • the fastening means comprises an adhesive tab such as is described in US Patent No 5,484,636, which is incorporated herein by reference.
  • the adhesive tab comprises a first end which is coated, on one side, with a relatively strong adhesive.
  • the first end of the adhesive tab being fixed to an end of either the first or second chambers.
  • the first end of the tab is fixed to the end of the smaller of the two chambers, usually the second chamber, i.e. the substrate reservoir.
  • the end of the chamber to which the adhesive tab is fixed is usually the end distal to the frangible member .
  • a second end of the adhesive tab is coated, on one side, with a relatively weak or at least peelable adhesive.
  • an adhesive may be provided with a 'dead' adhesive area for ease of opening.
  • the packaging systems may present in a folded form which, particularly in the case of sanitary tampons, allows them to be carried discreetly.
  • the packaging may be folded or rolled and the adhesive tab used to fasten the packaging together to aid disposal.
  • the used packaging may itself be used as a receptacle for used or soiled sanitary articles, e.g. a tampon.
  • the used tampon may be placed in the first chamber and the packaging system folded or rolled as herein before described for disposal.
  • Figure 1 is a plain cross-section of a system of the invention housing a digital tampon and a lubricant;
  • Figure 2 is a plain cross-section of a system of the invention in which the tampon has broken the frangible member
  • Figure 3 is a system of the invention in which the tampon has been drawn back out of the lubricant chamber;
  • Figure 4 is a side cross-section of a system of the invention housing a digital tampon
  • Figure 5 is a side cross-section of a system of the invention in which the tampon has broken the frangible member
  • Figure 6 is a side cross-section of a system of the invention in which the tampon is removed from the lubricant chamber and is coated with lubricant;
  • Figure 7 is a side cross-section of a system of the invention in which one of the chamber walls is peeled away to expose the tampon;
  • Figure 8 is a close up cross-section of the liftable tab;
  • Figure 9 is a plan cross-section of an applicator tampon system
  • Figure 10 is a plan cross-section of an applicator tampon system in which the frangible member has been ruptured
  • Figure 11 is a plan cross-section in which the applicator tampon has been coated with lubricant.
  • Figure 12 is a cross section view of the releasable folded system.
  • Figure 13 is a plan cross-section of the invention comprising a yoghurt and a fruit mix
  • Figure 14 is a plan cross-section of a sachet system in which the frangible member has been ruptured.
  • Figure 15 is a plan cross-section in which the yoghurt and fruit have been mixed together.
  • a packaging system (11) comprises a longitudinal cylinder and is provided with a first chamber (12) and a second chamber (13).
  • the chambers (12 and 13) being separated by a frangible member (14).
  • the first chamber (12) is adapted to house an article (15), e.g. a tampon.
  • the article is a tampon which comprises a domed end (16) and a flat distal end (17) and the second chamber (13) houses a substrate (18), e.g. a lubricant.
  • the tampon (25) is pushed via its flat end (26), either by hand or using a plunger, so that the domed end (26) breaks the frangible member (24).
  • the tampon (25) then enters the reservoir of the second chamber (23) and contacts the substrate (28).
  • the tampon (35) is removed from the second chamber (33), by retracting it through the frangible membrane (34), the tampon (35) being coated with substrate (38).
  • Figure 3 to 6 provide a longitudinal cross-section view of the process illustrated in Figures 1 to 3.
  • the end (711) of the first chamber (72), distal to the frangible member (not shown) is provided with a non-crimped, releasable region (710), which facilitates peeling apart the walls (711 and 712).
  • the end (811) of the first wall (89) is peeled away from the end (812) of the second wall (89).
  • the end (79) of the first chamber (72), distal to the frangible member (74) is provided with a non-crimped portion (10) which facilitates peeling apart of the walls (711 and 712) of the first chamber (72) and, optionally, the second chamber (73).
  • a packaging system (91) of the invention is used to house an applicator tampon (93).
  • the second chamber (93) is squeezed causing the- frangible member (94) to rupture, the lubricant (98) coats the applicator tampon (93).
  • the packaging system (121) is folded about the crimp line (124) between the first and second chambers (122 and 123).
  • the end (125) of the second chamber (123) distal to the crimp line (124) is provided with a tab (126).
  • a first end (127) of the tab (126) is coated with a relatively strong adhesive and is attached to the end (125) of the second chamber (123).
  • the second end (128) is attached to an outer wall of the first chamber (122). In use, the second end of the tab
  • the packaging system (126) may be peeled away to allow the packaging system to be used. After use, the packaging system may be rolled up and held together by re-adhering the second end
  • the used system may be used to discreetly dispose of soiled articles.
  • a packaging system (1) of the invention is used to house e.g. a yoghurt (1313) and a fruit sauce.
  • first (141) or the second chamber (143) is squeezed causing the frangible member (144) to rupture.
  • the yoghurt (1513) and fruit sauce (153) are mixed around the point indicated as (155).

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Packages (AREA)
  • Bag Frames (AREA)

Abstract

La présente invention concerne un système d'emballage (11) comprenant une première chambre (12) conçue pour renfermer une première matière (15) et une seconde chambre (13) conçue pour renfermer une seconde matière (18), la première et la seconde chambre étant séparées par un élément frangible (14). L'invention concerne également un emballage d'article hygiénique qui comprend un tel système.
PCT/GB2001/005622 2000-12-23 2001-12-21 Systeme d'emballage WO2002051718A1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AU2002216210A AU2002216210B2 (en) 2000-12-23 2001-12-21 Packaging system
CA002430490A CA2430490A1 (fr) 2000-12-23 2001-12-21 Systeme d'emballage
EP01272080A EP1351866A1 (fr) 2000-12-23 2001-12-21 Systeme d'emballage
GB0313397A GB2386361B (en) 2000-12-23 2001-12-21 Packaging system
JP2002552827A JP2004525823A (ja) 2000-12-23 2001-12-21 包装システム
US10/250,628 US20040112769A1 (en) 2000-12-23 2001-12-21 Packaging system
NO20032764A NO20032764L (no) 2000-12-23 2003-06-17 Pakkesystem

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0031655A GB0031655D0 (en) 2000-12-23 2000-12-23 Packaging system
GB0031655.4 2000-12-23
GB0100382.1 2001-01-06
GB0100382A GB0100382D0 (en) 2001-01-06 2001-01-06 Packaging system

Publications (1)

Publication Number Publication Date
WO2002051718A1 true WO2002051718A1 (fr) 2002-07-04

Family

ID=26245496

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2001/005622 WO2002051718A1 (fr) 2000-12-23 2001-12-21 Systeme d'emballage

Country Status (8)

Country Link
US (1) US20040112769A1 (fr)
EP (1) EP1351866A1 (fr)
JP (1) JP2004525823A (fr)
AU (1) AU2002216210B2 (fr)
CA (1) CA2430490A1 (fr)
GB (1) GB2386361B (fr)
NO (1) NO20032764L (fr)
WO (1) WO2002051718A1 (fr)

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US7744556B2 (en) 2005-03-25 2010-06-29 Kimberly-Clark Worldwide, Inc. Delivery tube assembly for an applicator
WO2010122376A1 (fr) * 2009-04-20 2010-10-28 Compagnie Gervais Danone Produits laitiers hypocaloriques
US7919453B2 (en) 2005-03-25 2011-04-05 Kimberly-Clark Worldwide, Inc. Dosage cap assembly for an applicator
US7993667B2 (en) 2005-03-25 2011-08-09 Kimberly-Clark Worldwide, Inc. Methods of manufacturing a medicated tampon assembly
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US7465766B2 (en) * 2004-01-08 2008-12-16 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
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US12036313B2 (en) * 2018-03-20 2024-07-16 Lanvira, Llc Personal lubricants comprising lambda-carrageenan
US12043598B2 (en) * 2018-03-20 2024-07-23 Lanvira, Llc Condoms lubricated with antiviral lubricious compositions containing lambda-carrageenan
CN109620547B (zh) * 2018-12-13 2021-07-09 湖南千金卫生用品股份有限公司 一种具有缓解妇科疾病功效的卫生棉条及其制备方法
WO2020142698A1 (fr) * 2019-01-05 2020-07-09 Foremost Technologies and Products, Inc. Traitement par haute pression d'aliments et de compléments
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GB2386361B (en) 2005-07-20
NO20032764D0 (no) 2003-06-17
GB2386361A (en) 2003-09-17
CA2430490A1 (fr) 2002-07-04
US20040112769A1 (en) 2004-06-17
EP1351866A1 (fr) 2003-10-15
JP2004525823A (ja) 2004-08-26
GB0313397D0 (en) 2003-07-16
NO20032764L (no) 2003-08-20

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