WO2001009370A3 - Nachweis und identifikation von bakterienstämmen - Google Patents

Nachweis und identifikation von bakterienstämmen Download PDF

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Publication number
WO2001009370A3
WO2001009370A3 PCT/DE2000/002495 DE0002495W WO0109370A3 WO 2001009370 A3 WO2001009370 A3 WO 2001009370A3 DE 0002495 W DE0002495 W DE 0002495W WO 0109370 A3 WO0109370 A3 WO 0109370A3
Authority
WO
WIPO (PCT)
Prior art keywords
sample
identification
detection
coupled
bacterial strains
Prior art date
Application number
PCT/DE2000/002495
Other languages
English (en)
French (fr)
Other versions
WO2001009370A2 (de
Inventor
Stefan Miller
Original Assignee
Profos Gmbh
Stefan Miller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CNB008014957A priority Critical patent/CN100334746C/zh
Application filed by Profos Gmbh, Stefan Miller filed Critical Profos Gmbh
Priority to AU66860/00A priority patent/AU781090B2/en
Priority to SI200030798T priority patent/SI1198713T1/sl
Priority to EP00954386A priority patent/EP1198713B1/de
Priority to DE50012134T priority patent/DE50012134D1/de
Priority to CA2380480A priority patent/CA2380480C/en
Priority to JP2001513625A priority patent/JP5339658B2/ja
Publication of WO2001009370A2 publication Critical patent/WO2001009370A2/de
Publication of WO2001009370A3 publication Critical patent/WO2001009370A3/de
Priority to US10/060,618 priority patent/US7087376B2/en
Priority to US11/445,451 priority patent/US20070042357A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2304/00—Chemical means of detecting microorganisms
    • C12Q2304/10—DNA staining
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Adornments (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Die vorliegende Erfindung betrifft ein Verfahren zum Nachweis von Bakterien, umfassend die folgenden Schritte: Kopplung von Bakteriophagen und/oder Bakterienphagenproteinen an einen Träger, Inkubieren des mit den Bakteriophagen und/oder Bakterienphagenproteinen gekoppelten Trägers mit einer Probe, gegebenenfalls Entfernen der Probe und der nicht an die Bakteriophagen und/oder Bakterienphagenproteine gebundenen Bakterien der Probe, gegebenenfalls Zugabe von die Bakterienmembran permeabilisierenden oder zerstörenden Substanzen, und Nachweisen der an die Bakteriophagen und/oder Bakterienphagenproteine gebundenen Bakterien der Probe, wobei die gebundenen Bakterien keinem Kultivierungsschritt unterzogen werden.
PCT/DE2000/002495 1999-07-23 2000-07-28 Nachweis und identifikation von bakterienstämmen WO2001009370A2 (de)

Priority Applications (9)

Application Number Priority Date Filing Date Title
CNB008014957A CN100334746C (zh) 1999-07-23 2000-07-24 荧光材料混合物、波长转换的浇注料和光源装置
AU66860/00A AU781090B2 (en) 1999-07-30 2000-07-28 Detection and identification of bacterial strains
SI200030798T SI1198713T1 (sl) 1999-07-30 2000-07-28 Dokazovanje in identifikacija bakterijskih sevov
EP00954386A EP1198713B1 (de) 1999-07-30 2000-07-28 Nachweis und identifikation von bakterienstämmen
DE50012134T DE50012134D1 (de) 1999-07-30 2000-07-28 Nachweis und identifikation von bakterienstämmen
CA2380480A CA2380480C (en) 1999-07-30 2000-07-28 Detection and identification of bacterial strains
JP2001513625A JP5339658B2 (ja) 1999-07-30 2000-07-28 細菌株の検出および同定
US10/060,618 US7087376B2 (en) 1999-07-30 2002-01-30 Detection and identification of bacterial strains
US11/445,451 US20070042357A1 (en) 1999-07-30 2006-05-31 Detection and identification of bacterial strains

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19936047 1999-07-30
DE19936047.2 1999-07-30

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/060,618 Continuation US7087376B2 (en) 1999-07-30 2002-01-30 Detection and identification of bacterial strains

Publications (2)

Publication Number Publication Date
WO2001009370A2 WO2001009370A2 (de) 2001-02-08
WO2001009370A3 true WO2001009370A3 (de) 2001-07-05

Family

ID=7916722

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2000/002495 WO2001009370A2 (de) 1999-07-23 2000-07-28 Nachweis und identifikation von bakterienstämmen

Country Status (12)

Country Link
US (2) US7087376B2 (de)
EP (1) EP1198713B1 (de)
JP (1) JP5339658B2 (de)
AT (1) ATE316655T1 (de)
AU (1) AU781090B2 (de)
CA (1) CA2380480C (de)
DE (2) DE50012134D1 (de)
DK (1) DK1198713T3 (de)
ES (1) ES2256028T3 (de)
PT (1) PT1198713E (de)
RU (1) RU2265061C2 (de)
WO (1) WO2001009370A2 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5423400A (en) * 1999-06-25 2001-01-31 Spring Diagnostics Ltd. Bacteriophage library useful for typing bacteria and system and method utilizingsame
DE10195935D2 (de) * 2001-02-01 2003-12-24 Profos Ag Nachweis und Identifikation von Bakteriengruppen
US20020192676A1 (en) * 2001-06-18 2002-12-19 Madonna Angelo J. Method for determining if a type of bacteria is present in a mixture
DE10129815A1 (de) 2001-06-24 2003-01-09 Profos Ag Verfahren zur Aufreinigung von Bakterienzellen und Zellbestandteilen
WO2003008564A2 (en) 2001-07-18 2003-01-30 Instytut Immunologii I Terapii Doswiadczalnej Pan Methods of polyvalent bacteriophage preparation for the treatment of bacterial infections
FR2829500B1 (fr) * 2001-09-13 2003-12-12 Hemosystem Procede de concentration et de detection de germes pathogenes a partir de produits sanguins et/ou de leurs derives et dispositif pour le mettre en oeuvre
DE60332740D1 (de) * 2002-04-12 2010-07-08 Colorado School Of Mines Golde Verfahren zum nachweis geringer konzentrationen eines zielbakteriums unter verwendung von phagen zur infizierung von zielbakterienzellen
US8216780B2 (en) * 2002-04-12 2012-07-10 Microphage (Tm) Incorporated Method for enhanced sensitivity in bacteriophage-based diagnostic assays
US20050003346A1 (en) * 2002-04-12 2005-01-06 Colorado School Of Mines Apparatus and method for detecting microscopic living organisms using bacteriophage
GB0209680D0 (en) * 2002-04-27 2002-06-05 Univ Strathclyde Immobilisation and stabilisation of bacteriophage
ATE345502T1 (de) 2002-06-24 2006-12-15 Profos Ag Verfahren zum nachweis und zur entfernung von endotoxin
CA2501648A1 (en) * 2002-10-15 2004-04-29 Regents Of The University Of Minnesota Assays to detect or quantify bacterial or viral pathogens and contaminants
US20040197833A1 (en) * 2003-04-03 2004-10-07 Danisco A/S Method for the enrichment of target cells by use of CBDs
CN101375163B (zh) * 2003-04-10 2012-03-21 科罗拉多矿业学院 用噬菌体检测微观活生物体的装置与方法
WO2005001475A2 (en) 2003-04-10 2005-01-06 Kent Voorhees Apparatus and method for detecting microscopic living organisms using bacteriophage
US20090286225A1 (en) * 2004-02-13 2009-11-19 Microphagetm Incorporated Method and apparatus for bacteriophage-based diagnostic assays
US20050250096A1 (en) * 2004-02-13 2005-11-10 Microphage, Incorporated Microorganism detection using bacteriophage amplification
US20080241819A1 (en) * 2006-10-31 2008-10-02 Microphage (Tm) Incorporated Method and apparatus for enhanced bacteriophage-based diagnostic assays by selective inhibition of potential cross-reactive organisms
US7632637B1 (en) * 2004-07-19 2009-12-15 The United States Of America As Represented By The Secretary Of The Navy Technique for orienting and binding phage for bacteria detection
CA2593992A1 (en) * 2004-12-06 2006-06-15 Rodney M. Donlan Inhibition of biofilm formation using bacteriophage
RU2007136757A (ru) * 2005-03-04 2009-04-10 Блэйз Венчер Текнолоджиз Лимитед (Gb) Способ и устройство для отбора бактериальных проб
US20110097702A1 (en) * 2005-03-31 2011-04-28 Voorhees Kent J Methods and compositions for in situ detection of microorganisms on a surface
WO2006105504A1 (en) * 2005-03-31 2006-10-05 Microphage Incorporated Apparatus and method for detecting microorganisms using flagged bacteriophage
WO2007065423A1 (de) * 2005-12-05 2007-06-14 Technische Universität Dresden Verfahren und vorrichtung zur detektion von mikroorganismen und/oder deren aktivität
US20070178450A1 (en) * 2006-01-27 2007-08-02 Microphage (Tm) Incorporation Method and apparatus for determining level of microorganisms using bacteriophage
JP5150856B2 (ja) * 2007-06-15 2013-02-27 マイクロファージ・インコーポレーテッド バクテリオファージ増幅を向上させた微生物の検出方法
WO2009076668A2 (en) * 2007-12-13 2009-06-18 Alpharma, Inc. Bacteriophage preparations and method of use thereof
US8697434B2 (en) * 2008-01-11 2014-04-15 Colorado School Of Mines Detection of phage amplification by SERS nanoparticles
WO2009091501A1 (en) * 2008-01-18 2009-07-23 Response Biomedical Corporation Heated assays for influenza
FR2928656B1 (fr) * 2008-03-14 2011-08-26 Biomerieux Sa Procede de detection en temps reel de microorganismes dans un milieu de culture liquide par agglutination.
ES2325825B1 (es) * 2008-03-17 2010-06-25 Consejo Superior De Investigaciones Cientificas (Csic) (75%) Procedimiento y sistema para detectar y/o cuantificar bacteriofagos susceptibles de infectar una cepa huesped bacteriana predeterminada, uso de un dispositivo microelectronico sensor para detectar dichos bacteriofagos y dispositivo microelectronico sensor para llevar a cabo dicho.
US9441204B2 (en) * 2008-04-03 2016-09-13 Colorado School Of Mines Compositions and methods for detecting Yersinia pestis bacteria
EP2141176B1 (de) * 2008-07-04 2011-08-17 Biomérieux S.A. Neue bakteriophage Haftproteine
PL215522B1 (pl) 2008-09-29 2013-12-31 Inst Immunologii I Terapii Doswiadczalnej Pan Nowe szczepy bakteriofagów do leczenia zakazen bakteryjnych, zwlaszcza szczepami bakterii lekoopornych rodzaju Enterococcus
PL212258B1 (pl) 2010-06-20 2012-09-28 Inst Immunologii I Terapii Doswiadczalnej Pan Nowe szczepy bakteriofagów do leczenia zakazen bakteryjnych, zwlaszcza szczepami bakterii lekoopornych rodzaju Stenotrophomonas
CA2837731C (en) * 2011-06-28 2018-05-22 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Controlled covalent attachment of bioactive bacteriophage for regulating biofilm development
RU2476876C1 (ru) * 2011-07-08 2013-02-27 Сергей Иванович Трофимов Экспрессный способ определения микробного загрязнения водной среды
US10364453B1 (en) * 2013-02-04 2019-07-30 The United States Of America, As Represented By The Secretary Of The Navy Detecting of bacteria using fluorescently-labeled phage immobilized on an optically transparent surface
DE102013106462B3 (de) * 2013-06-20 2014-10-09 Airbus Defence and Space GmbH Detektionsverfahren zur Detektion von Bakterien, Verfahren zur Herstellung von Fusionsproteinen und Fusionsprotein
DE102015121035A1 (de) 2015-12-03 2017-06-08 Airbus Defence and Space GmbH Verfahren zur Detektion coliformer Keime
DE102015121034B4 (de) 2015-12-03 2022-06-23 Airbus Defence and Space GmbH Verfahren und Vorrichtung zur Anreicherung von biologischen Partikeln
CN116586132A (zh) * 2023-06-07 2023-08-15 宁波大学 一种耦合噬菌体修饰生物传感器的微流控芯片及其定量检测细菌的方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017129A1 (en) * 1992-02-28 1993-09-02 Judkins Paul W Method and diagnostic kit for determination of bacteria
WO1994006931A1 (en) * 1992-09-22 1994-03-31 The Minister Of Agriculture Fisheries And Food In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Method and kits for detection of bacteria
WO1997022713A1 (en) * 1995-12-15 1997-06-26 Biotec Laboratories Limited Method to detect bacteria
US5824468A (en) * 1995-05-18 1998-10-20 Merck Patent Gesellschaft Mit Beschrankkter Haftung Detection of listeria by means of recombinant bacteriophages
WO1998048042A2 (en) * 1997-04-18 1998-10-29 Minnesota Mining And Manufacturing Company Methods and devices for detecting bacteriophage

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE36604T1 (de) * 1983-10-26 1988-09-15 Lembke Juergen Neues verfahren zum virus-nachweis in reinkulturen mikroskopischer kleinlebewesen sowie in lebensmitteln und in technologischen produkten.
US4797363A (en) * 1984-03-19 1989-01-10 Board Of Trustees, University Of Illinois Bacteriophages as recognition and identification agents
WO1985004189A1 (en) * 1984-03-19 1985-09-26 Teodorescu Marius C Bacteriophages as recognition and identification agents
US5236826A (en) * 1985-12-10 1993-08-17 Murex Corporation Immunoassay for the detection or quantitation of an analyte
US5759774A (en) * 1988-05-18 1998-06-02 Cobe Laboratories, Inc. Method of detecting circulating antibody types using dried or lyophilized cells
JPH0253500A (ja) * 1988-08-16 1990-02-22 Mitsubishi Heavy Ind Ltd バクテリオファージの検出方法
WO1990004041A1 (en) * 1988-10-04 1990-04-19 Dna Plant Technology Corporation Bacterial detection by phage transduction of detectable phenotype
US5168037A (en) * 1990-08-02 1992-12-01 Phyllis Entis Method for the preparation of a labelled virus without the inactivation of viral binding sites and method of assay utilizing said labelled virus
US5981179A (en) * 1991-11-14 1999-11-09 Digene Diagnostics, Inc. Continuous amplification reaction
US6022748A (en) * 1997-08-29 2000-02-08 Sandia Corporation - New Mexico Regents Of The University Of California Sol-gel matrices for direct colorimetric detection of analytes
CA2130072C (en) * 1994-08-12 2003-02-18 John W. Cherwonogrodzky Method of detecting a pathogen using a virus
US5919617A (en) * 1994-12-21 1999-07-06 Miami University Methods and reagents for detecting fungal pathogens in a biological sample
US5712172A (en) * 1995-05-18 1998-01-27 Wyntek Diagnostics, Inc. One step immunochromatographic device and method of use
US6319668B1 (en) * 1995-04-25 2001-11-20 Discovery Partners International Method for tagging and screening molecules
US5935804A (en) * 1997-03-21 1999-08-10 Laine; Roger A. Method for detecting eubacteria in biological samples with catalytically inactive murein binding enzymes

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993017129A1 (en) * 1992-02-28 1993-09-02 Judkins Paul W Method and diagnostic kit for determination of bacteria
WO1994006931A1 (en) * 1992-09-22 1994-03-31 The Minister Of Agriculture Fisheries And Food In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Method and kits for detection of bacteria
US5824468A (en) * 1995-05-18 1998-10-20 Merck Patent Gesellschaft Mit Beschrankkter Haftung Detection of listeria by means of recombinant bacteriophages
WO1997022713A1 (en) * 1995-12-15 1997-06-26 Biotec Laboratories Limited Method to detect bacteria
WO1998048042A2 (en) * 1997-04-18 1998-10-29 Minnesota Mining And Manufacturing Company Methods and devices for detecting bacteriophage

Also Published As

Publication number Publication date
DE10036931B4 (de) 2004-06-03
EP1198713B1 (de) 2006-01-25
JP5339658B2 (ja) 2013-11-13
DE50012134D1 (de) 2006-04-13
CA2380480A1 (en) 2001-02-08
US20020127547A1 (en) 2002-09-12
DE10036931A1 (de) 2001-05-23
PT1198713E (pt) 2006-06-30
CA2380480C (en) 2010-10-26
DK1198713T3 (da) 2006-05-01
AU781090B2 (en) 2005-05-05
WO2001009370A2 (de) 2001-02-08
RU2265061C2 (ru) 2005-11-27
ES2256028T3 (es) 2006-07-16
US20070042357A1 (en) 2007-02-22
AU6686000A (en) 2001-02-19
ATE316655T1 (de) 2006-02-15
JP2003505105A (ja) 2003-02-12
US7087376B2 (en) 2006-08-08
EP1198713A2 (de) 2002-04-24

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