WO2000029611A3 - Neue primer und sonden zum nachweis von hiv - Google Patents

Neue primer und sonden zum nachweis von hiv Download PDF

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Publication number
WO2000029611A3
WO2000029611A3 PCT/EP1999/008211 EP9908211W WO0029611A3 WO 2000029611 A3 WO2000029611 A3 WO 2000029611A3 EP 9908211 W EP9908211 W EP 9908211W WO 0029611 A3 WO0029611 A3 WO 0029611A3
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WO
WIPO (PCT)
Prior art keywords
probes
region
detecting hiv
novel primers
hiv
Prior art date
Application number
PCT/EP1999/008211
Other languages
English (en)
French (fr)
Other versions
WO2000029611A2 (de
Inventor
Gerd Haberhausen
Pia Kasper
Christoph Kessler
Original Assignee
Roche Diagnostics Gmbh
Gerd Haberhausen
Pia Kasper
Christoph Kessler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh, Gerd Haberhausen, Pia Kasper, Christoph Kessler filed Critical Roche Diagnostics Gmbh
Priority to JP2000582592A priority Critical patent/JP2004500014A/ja
Priority to EP99969965A priority patent/EP1124993A2/de
Publication of WO2000029611A2 publication Critical patent/WO2000029611A2/de
Publication of WO2000029611A3 publication Critical patent/WO2000029611A3/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • AIDS & HIV (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Die Erfindung betrifft ein Verfahren zum subtyp- und/oder speziesübergreifenden Nachweis von HI-Viren in einer Probe unter Verwendung mindestens eines Oligonukleotids, welches mindestens 10 aufeinanderfolgende Nukleotide aus (i) einer hochkonservierten Region der LTR-Region, des gag-Gens oder des pol-Gens von HIV, (ii) einer entsprechenden Region eines anderen HI-Virusisolats, (iii) einer entsprechenden Region einer aus mehreren HI-Virusisolaten stammenden Konsensussequenz, oder dazu komplementären Sequenzen enthält.
PCT/EP1999/008211 1998-10-30 1999-10-29 Neue primer und sonden zum nachweis von hiv WO2000029611A2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2000582592A JP2004500014A (ja) 1998-10-30 1999-10-29 Ｈｉｖを検出するための新規のプライマーおよびプローブ
EP99969965A EP1124993A2 (de) 1998-10-30 1999-10-29 Neue primer und sonden zum nachweis von hiv

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19850186.2 1998-10-30
DE1998150186 DE19850186A1 (de) 1998-10-30 1998-10-30 Neue Primer und Sonden zum Nachweis von HIV

Publications (2)

Publication Number Publication Date
WO2000029611A2 WO2000029611A2 (de) 2000-05-25
WO2000029611A3 true WO2000029611A3 (de) 2000-10-26

Family

ID=7886230

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/008211 WO2000029611A2 (de) 1998-10-30 1999-10-29 Neue primer und sonden zum nachweis von hiv

Country Status (4)

Country Link
EP (1) EP1124993A2 (de)
JP (1) JP2004500014A (de)
DE (1) DE19850186A1 (de)
WO (1) WO2000029611A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE421999T1 (de) 1999-07-09 2009-02-15 Gen Probe Inc Nachweis von hiv-1 durch amplifizierung von nukleinsäuren
DE60045932D1 (de) * 2000-09-01 2011-06-16 Gen Probe Inc HIV-1-Sequenzverstärkung zur Erkennung von Sequenzen in Zusammenhang mit Wirkstoffresistenz-Mutationen
US6582920B2 (en) 2000-09-01 2003-06-24 Gen-Probe Incorporated Amplification of HIV-1 RT sequences for detection of sequences associated with drug-resistance mutations
US6852491B2 (en) * 2001-09-04 2005-02-08 Abbott Laboratories Amplification and detection reagents for HIV-1
WO2005121379A2 (en) 2004-06-07 2005-12-22 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION Real-time pcr point mutation assays for detecting hiv-1 resistance to antiviral drugs
WO2007055260A1 (ja) * 2005-11-11 2007-05-18 Japan Health Sciences Foundation 人免疫不全ウイルス－１遺伝子検出又は定量用材料，検出又は定量方法，治療用遺伝子断片，及び治療方法
AU2006323930B2 (en) * 2005-12-07 2012-06-21 Janssen Sciences Ireland Uc Methods, plasmid vectors and primers for assessing HIV viral fitness
WO2007069331A1 (ja) * 2005-12-16 2007-06-21 Eiken Kagaku Kabushiki Kaisha ヒト免疫不全ウイルス１型の検出方法
JP6593984B2 (ja) * 2014-09-26 2019-10-23 株式会社Ｋｒｉ Ｒｎａ増幅法およびｈｉｖ−１感染診断方法
DE102015009439B4 (de) * 2015-07-21 2017-07-06 GFE Blut mbH Triple Target HIV-1 NAT zum Nachweis aller bekannten Genotypen
JP6858008B2 (ja) * 2016-11-30 2021-04-14 シスメックス株式会社 粒子分散装置及び粒子分散方法
CN109576397B (zh) * 2018-12-28 2022-10-14 广州达安基因股份有限公司 一种人类免疫缺陷病毒1型核酸定量检测试剂盒
CN116064922A (zh) * 2021-10-29 2023-05-05 京东方科技集团股份有限公司 一种人类免疫缺陷病毒1型核酸测定试剂盒及其操作方法

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0229701A2 (de) * 1986-01-10 1987-07-22 F. Hoffmann-La Roche Ag Nachweis von Viren durch Verstärkung und Hybridisation
WO1992015708A1 (en) * 1991-02-27 1992-09-17 Amoco Corporation Methods for improving the sensitivity of hybridization assays
EP0516540A1 (de) * 1991-05-31 1992-12-02 Cis Bio International Oligonukleotide für den in vitro Nachweis von HIV-Retroviren-Infektionen und Verfahren für den Nachweis von HIV-Retroviren
EP0617132A2 (de) * 1993-03-26 1994-09-28 Gen-Probe Incorporated Gensonden und Verfahren zum Nachweis vom menschlichen Immunschwäche-Virus Typ 1
WO1995021912A1 (en) * 1994-02-14 1995-08-17 The Macfarlane Burnet Centre For Medical Research Limited Non-pathogenic strains of hiv-1
WO1996002557A1 (en) * 1994-07-19 1996-02-01 Gen-Probe Incorporated Compounds and methods for inhibiting propagation of human immunodeficiency virus
EP0727497A1 (de) * 1995-02-17 1996-08-21 F. Hoffmann-La Roche Ag Primers und Sonden zum Nachweis von HIV
EP0806484A2 (de) * 1989-06-02 1997-11-12 Institut Pasteur Nukleotid-Sequenzen von HIV-1, HIV-2 and SIV Retrovirusgenomen, ihre Verwendung zur Amplifizierung von diesen Retroviren und zur in vitro Diagnostik von diesen Viren verursachten Infektionen
EP0839917A1 (de) * 1996-10-24 1998-05-06 Roche Diagnostics GmbH Primer und Sonden zum Nachweis von HIV
EP0854197A2 (de) * 1997-01-17 1998-07-22 F. Hoffmann-La Roche Ag Primern zum Nachweis von HIV-1
WO1998044945A1 (en) * 1997-04-04 1998-10-15 The Immune Response Corporation Non-infectious, protease defective hiv particles and nucleic acid molecules encoding therefor
WO1998058086A2 (en) * 1997-06-16 1998-12-23 Abbott Laboratories Nucleic acid primers and probes for detecting hiv-1 and hiv-2
EP0887427A2 (de) * 1997-06-25 1998-12-30 Ortho-Clinical Diagnostics, Inc. Amplifizierung und Detektion von HIV-1 und/oder HIV-2
WO1999007898A1 (en) * 1997-08-08 1999-02-18 Akzo Nobel N.V. Nucleic acid sequences that can be used as primers and probes in the amplification and detection of all subtypes of hiv-1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030714A (en) * 1986-06-23 1991-07-09 Institut Pasteur Variant of LAV viruses
EP0425563B1 (de) * 1988-07-20 1996-05-15 David Segev Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen
AU6237198A (en) * 1996-12-19 1998-07-15 Isis Pharmaceuticals, Inc. Large-scale purification of full length oligonucleotides by solid-liquid affinity extraction

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0229701A2 (de) * 1986-01-10 1987-07-22 F. Hoffmann-La Roche Ag Nachweis von Viren durch Verstärkung und Hybridisation
EP0806484A2 (de) * 1989-06-02 1997-11-12 Institut Pasteur Nukleotid-Sequenzen von HIV-1, HIV-2 and SIV Retrovirusgenomen, ihre Verwendung zur Amplifizierung von diesen Retroviren und zur in vitro Diagnostik von diesen Viren verursachten Infektionen
WO1992015708A1 (en) * 1991-02-27 1992-09-17 Amoco Corporation Methods for improving the sensitivity of hybridization assays
EP0516540A1 (de) * 1991-05-31 1992-12-02 Cis Bio International Oligonukleotide für den in vitro Nachweis von HIV-Retroviren-Infektionen und Verfahren für den Nachweis von HIV-Retroviren
EP0617132A2 (de) * 1993-03-26 1994-09-28 Gen-Probe Incorporated Gensonden und Verfahren zum Nachweis vom menschlichen Immunschwäche-Virus Typ 1
WO1995021912A1 (en) * 1994-02-14 1995-08-17 The Macfarlane Burnet Centre For Medical Research Limited Non-pathogenic strains of hiv-1
WO1996002557A1 (en) * 1994-07-19 1996-02-01 Gen-Probe Incorporated Compounds and methods for inhibiting propagation of human immunodeficiency virus
EP0727497A1 (de) * 1995-02-17 1996-08-21 F. Hoffmann-La Roche Ag Primers und Sonden zum Nachweis von HIV
EP0839917A1 (de) * 1996-10-24 1998-05-06 Roche Diagnostics GmbH Primer und Sonden zum Nachweis von HIV
EP0854197A2 (de) * 1997-01-17 1998-07-22 F. Hoffmann-La Roche Ag Primern zum Nachweis von HIV-1
WO1998044945A1 (en) * 1997-04-04 1998-10-15 The Immune Response Corporation Non-infectious, protease defective hiv particles and nucleic acid molecules encoding therefor
WO1998058086A2 (en) * 1997-06-16 1998-12-23 Abbott Laboratories Nucleic acid primers and probes for detecting hiv-1 and hiv-2
EP0887427A2 (de) * 1997-06-25 1998-12-30 Ortho-Clinical Diagnostics, Inc. Amplifizierung und Detektion von HIV-1 und/oder HIV-2
WO1999007898A1 (en) * 1997-08-08 1999-02-18 Akzo Nobel N.V. Nucleic acid sequences that can be used as primers and probes in the amplification and detection of all subtypes of hiv-1

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DE BAAR M ET AL: "Design and evaluation of a Human Immunodeficiency Virus Type 1.", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 37, no. 6, - June 1999 (1999-06-01), pages 1813 - 18, XP000923207 *
EMBL Database Entry AGPROTF3, Accession number M24551, 6 July 1989: Louis jm et al.: Human immunodeficiency virus (HIV-1) synthetic protease *

Also Published As

Publication number Publication date
WO2000029611A2 (de) 2000-05-25
EP1124993A2 (de) 2001-08-22
JP2004500014A (ja) 2004-01-08
DE19850186A1 (de) 2000-05-25

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