WO2000025750A1 - Compositions de metamizole a liberation prolongee - Google Patents

Compositions de metamizole a liberation prolongee Download PDF

Info

Publication number
WO2000025750A1
WO2000025750A1 PCT/EP1999/008120 EP9908120W WO0025750A1 WO 2000025750 A1 WO2000025750 A1 WO 2000025750A1 EP 9908120 W EP9908120 W EP 9908120W WO 0025750 A1 WO0025750 A1 WO 0025750A1
Authority
WO
WIPO (PCT)
Prior art keywords
controlled
metamizole
release tablets
fatty
tablets according
Prior art date
Application number
PCT/EP1999/008120
Other languages
English (en)
Inventor
Mauro Valenti
Flavio Fabiani
Original Assignee
Farmaceutici Formenti S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Formenti S.P.A. filed Critical Farmaceutici Formenti S.P.A.
Priority to AU11550/00A priority Critical patent/AU1155000A/en
Publication of WO2000025750A1 publication Critical patent/WO2000025750A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

Compositions solides à libération prolongée pour administration orale, obtenues en soumettant le principe actif et un composé gras à la granulation par fusion, puis en mélangeant le granulat obtenu avec un polymère hydrophile et des excipients classiques.
PCT/EP1999/008120 1998-11-03 1999-10-27 Compositions de metamizole a liberation prolongee WO2000025750A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU11550/00A AU1155000A (en) 1998-11-03 1999-10-27 Controlled-release formulations of metamizole

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI98A002365 1998-11-03
IT1998MI002365A IT1303693B1 (it) 1998-11-03 1998-11-03 Composizioni a rilascio controllato di metamizolo.

Publications (1)

Publication Number Publication Date
WO2000025750A1 true WO2000025750A1 (fr) 2000-05-11

Family

ID=11380995

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/008120 WO2000025750A1 (fr) 1998-11-03 1999-10-27 Compositions de metamizole a liberation prolongee

Country Status (6)

Country Link
AR (1) AR020998A1 (fr)
AU (1) AU1155000A (fr)
CO (1) CO5160319A1 (fr)
IT (1) IT1303693B1 (fr)
PE (1) PE20001231A1 (fr)
WO (1) WO2000025750A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000066088A1 (fr) * 1999-05-04 2000-11-09 Hexal Ag Composition pharmaceutique a liberation controlee contenant du metamizol
US20110046072A1 (en) * 2008-05-07 2011-02-24 Bayer Animal Health Gmbh Solid pharmaceutical formulation with delayed release
WO2018087109A1 (fr) 2016-11-08 2018-05-17 Grünenthal GmbH Forme galénique multiparticulaire à libération de métamizole contrôlée
US10682337B2 (en) * 2015-03-03 2020-06-16 Kindred Biosciences, Inc. Compositions and methods for treatment and prevention of pyrexia in horses

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998047534A1 (fr) * 1997-04-18 1998-10-29 Klinge Pharma Gmbh Medicaments stabilises renfermant des derives cysteinyle

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998047534A1 (fr) * 1997-04-18 1998-10-29 Klinge Pharma Gmbh Medicaments stabilises renfermant des derives cysteinyle

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 91, no. 10, 3 September 1979, Columbus, Ohio, US; abstract no. 78844, XP002110962 *
L.V.N.PRISTA ET AL.: "COMPRESSED DIPYRONE TABLETS WITH PROLONGED ACTION", AN. FAC. FARM. UNIV. FED. PERNAMBUCO (BR), vol. 15, 1976, pages 57 - 68 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000066088A1 (fr) * 1999-05-04 2000-11-09 Hexal Ag Composition pharmaceutique a liberation controlee contenant du metamizol
US20110046072A1 (en) * 2008-05-07 2011-02-24 Bayer Animal Health Gmbh Solid pharmaceutical formulation with delayed release
US10682337B2 (en) * 2015-03-03 2020-06-16 Kindred Biosciences, Inc. Compositions and methods for treatment and prevention of pyrexia in horses
WO2018087109A1 (fr) 2016-11-08 2018-05-17 Grünenthal GmbH Forme galénique multiparticulaire à libération de métamizole contrôlée

Also Published As

Publication number Publication date
IT1303693B1 (it) 2001-02-23
ITMI982365A1 (it) 2000-05-03
CO5160319A1 (es) 2002-05-30
PE20001231A1 (es) 2000-11-29
AR020998A1 (es) 2002-06-05
AU1155000A (en) 2000-05-22

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