WO1998056793A1 - 3-SUBSTITUIERTE PYRIDO [3',4':4,5] THIENO [2,3-d] PYRIMIDIN-DERIVATE, IHRE HERSTELLUNG UND VERWENDUNG - Google Patents
3-SUBSTITUIERTE PYRIDO [3',4':4,5] THIENO [2,3-d] PYRIMIDIN-DERIVATE, IHRE HERSTELLUNG UND VERWENDUNG Download PDFInfo
- Publication number
- WO1998056793A1 WO1998056793A1 PCT/EP1998/003231 EP9803231W WO9856793A1 WO 1998056793 A1 WO1998056793 A1 WO 1998056793A1 EP 9803231 W EP9803231 W EP 9803231W WO 9856793 A1 WO9856793 A1 WO 9856793A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- alkyl
- thieno
- ethyl
- substituted
- pyrido
- Prior art date
Links
- 0 C*N(C)C(c1c(N=C)[s]c2c1CN(*)CC2)=* Chemical compound C*N(C)C(c1c(N=C)[s]c2c1CN(*)CC2)=* 0.000 description 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP50145999A JP2002504104A (ja) | 1997-06-13 | 1998-05-29 | 3−置換ピリド[3’,4’:4,5]チエノ[2,3−d]ピリミジン誘導体、その合成方法および使用 |
AT98936299T ATE256686T1 (de) | 1997-06-13 | 1998-05-29 | 3-substituierte pyrido 3',4':4,5) thieno 2,3-d) pyrimidin-derivate, ihre herstellung und verwendung |
BR9810008-4A BR9810008A (pt) | 1997-06-13 | 1998-05-29 | Derivado de 3-subistituìdo 3,4,5,6,7,8-haxaidropirido [3',4' : 4, 5] tieno [2,3-d] pirimidina, e, uso do mesmo. |
US09/445,178 US6159981A (en) | 1997-06-13 | 1998-05-29 | 3-substituted pyrido [3',4':4,5] Thieno [2,3-d] pyrimidine derivatives, and production and use of the same |
DE59810485T DE59810485D1 (de) | 1997-06-13 | 1998-05-29 | 3-SUBSTITUIERTE PYRIDO 3',4':4,5] THIENO 2,3-d] PYRIMIDIN-DERIVATE, IHRE HERSTELLUNG UND VERWENDUNG |
NZ502237A NZ502237A (en) | 1997-06-13 | 1998-05-29 | 3-substituted pyrido [3',4':4,5] thieno [2,3-d] pyrimidine derivatives for treating 5-HT1B/D receptor related disorders which increases serotonin release in the brain |
EP98936299A EP1023296B1 (de) | 1997-06-13 | 1998-05-29 | 3-SUBSTITUIERTE PYRIDO 3',4':4,5] THIENO 2,3-d] PYRIMIDIN-DERIVATE, IHRE HERSTELLUNG UND VERWENDUNG |
CA002293440A CA2293440A1 (en) | 1997-06-13 | 1998-05-29 | 3-substituted pyrido [3',4':4,5] thieno [2,3-d] pyrimidine derivatives, and production and use of the same |
IL13298598A IL132985A0 (en) | 1997-06-13 | 1998-05-29 | 3-Substituted pyrido ¬3'4':4,5¾thieno ¬2,3-d¾pyrimidine derivatives and production and use of the same |
PL98337454A PL337454A1 (en) | 1997-06-13 | 1998-05-29 | 3-substituted derivatives of pyrido [3',4',4,5] thiene [2,3-d] pyrimidine, method of obtaining them and their application |
AU85357/98A AU748697B2 (en) | 1997-06-13 | 1998-05-29 | 3-substituted pyrido {3',4':4,5} thieno {2,3-D} pyrimidine derivatives, and production and use of the same |
SK1743-99A SK174399A3 (en) | 1997-06-13 | 1998-05-29 | 3-substituted pyrido [3',4':4,5] thieno [2,3-d] pyrimidine derivatives, and production and use of the same |
BG103921A BG103921A (en) | 1997-06-13 | 1999-11-24 | 3-substituted pyrido[3',4':4,5]thieno[2,3-d]pyrimidine derivatives, their preparation and application |
NO996045A NO996045D0 (no) | 1997-06-13 | 1999-12-08 | 3-Substituerte pyrido[3',4':4,5]tieno[2,3-d]pyrimidin- derivater, fremstilling og anvendelse derav |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19724979.5 | 1997-06-13 | ||
DE19724979A DE19724979A1 (de) | 1997-06-13 | 1997-06-13 | 3-substituierte Pyrido [3,4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1998056793A1 true WO1998056793A1 (de) | 1998-12-17 |
Family
ID=7832351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1998/003231 WO1998056793A1 (de) | 1997-06-13 | 1998-05-29 | 3-SUBSTITUIERTE PYRIDO [3',4':4,5] THIENO [2,3-d] PYRIMIDIN-DERIVATE, IHRE HERSTELLUNG UND VERWENDUNG |
Country Status (27)
Country | Link |
---|---|
US (1) | US6159981A (de) |
EP (1) | EP1023296B1 (de) |
JP (1) | JP2002504104A (de) |
KR (1) | KR20010013698A (de) |
CN (1) | CN1259954A (de) |
AR (1) | AR014354A1 (de) |
AT (1) | ATE256686T1 (de) |
AU (1) | AU748697B2 (de) |
BG (1) | BG103921A (de) |
BR (1) | BR9810008A (de) |
CA (1) | CA2293440A1 (de) |
CO (1) | CO4940481A1 (de) |
DE (2) | DE19724979A1 (de) |
ES (1) | ES2215312T3 (de) |
HR (1) | HRP980318A2 (de) |
HU (1) | HUP0002736A3 (de) |
ID (1) | ID24045A (de) |
IL (1) | IL132985A0 (de) |
MY (1) | MY132993A (de) |
NO (1) | NO996045D0 (de) |
NZ (1) | NZ502237A (de) |
PL (1) | PL337454A1 (de) |
SK (1) | SK174399A3 (de) |
TR (1) | TR199903061T2 (de) |
TW (1) | TW479059B (de) |
WO (1) | WO1998056793A1 (de) |
ZA (1) | ZA985120B (de) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002002569A1 (de) * | 2000-07-03 | 2002-01-10 | Abbott Gmbh & Co. Kg | Substituierte thienopyrimidin derivate und ihre verwendung zur prophylaxe und therapie der zerebralen ischämie |
US6387912B1 (en) | 1999-01-11 | 2002-05-14 | Basf Aktiengesellschaft | Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia |
WO2004055024A1 (de) * | 2002-12-18 | 2004-07-01 | Abbott Gmbh & Co. Kg | 3-substituierte 3,4-dihydro-thieno[2,3-d]pyrimidin-4-on-derivate, ihre herstellung und verwendung |
CN100370989C (zh) * | 1999-01-11 | 2008-02-27 | Basf公司 | 5-ht5配体在制备治疗神经变性疾病的药物中的应用 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8877316B2 (en) * | 2002-12-20 | 2014-11-04 | The Procter & Gamble Company | Cloth-like personal care articles |
CN101627013A (zh) | 2007-02-07 | 2010-01-13 | 安斯泰来制药有限公司 | 酰基胍衍生物 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4835157A (en) * | 1988-03-15 | 1989-05-30 | Ortho Pharmaceutical Corporation | Thieno- and furopyrimidine-2,4-dione piperidine derivatives as serotonin antagonists and alpha adrenergic blocking agents |
EP0329168A2 (de) * | 1988-02-18 | 1989-08-23 | Bristol-Myers Squibb Company | Psychotropische Heterobicycloalkylpiperazinderivate |
WO1998011110A1 (de) * | 1996-09-10 | 1998-03-19 | Basf Aktiengesellschaft | 3-substituierte pyrido [4',3':4,5] thieno [2,3-d]pyrimidin-derivate, ihre herstellung und verwendung |
-
1997
- 1997-06-13 DE DE19724979A patent/DE19724979A1/de not_active Withdrawn
-
1998
- 1998-05-29 WO PCT/EP1998/003231 patent/WO1998056793A1/de not_active Application Discontinuation
- 1998-05-29 TR TR1999/03061T patent/TR199903061T2/xx unknown
- 1998-05-29 EP EP98936299A patent/EP1023296B1/de not_active Expired - Lifetime
- 1998-05-29 PL PL98337454A patent/PL337454A1/xx not_active Application Discontinuation
- 1998-05-29 ES ES98936299T patent/ES2215312T3/es not_active Expired - Lifetime
- 1998-05-29 KR KR1019997011713A patent/KR20010013698A/ko not_active Application Discontinuation
- 1998-05-29 HU HU0002736A patent/HUP0002736A3/hu unknown
- 1998-05-29 BR BR9810008-4A patent/BR9810008A/pt not_active IP Right Cessation
- 1998-05-29 AU AU85357/98A patent/AU748697B2/en not_active Ceased
- 1998-05-29 SK SK1743-99A patent/SK174399A3/sk unknown
- 1998-05-29 ID IDW991495A patent/ID24045A/id unknown
- 1998-05-29 AT AT98936299T patent/ATE256686T1/de not_active IP Right Cessation
- 1998-05-29 CA CA002293440A patent/CA2293440A1/en not_active Abandoned
- 1998-05-29 IL IL13298598A patent/IL132985A0/xx unknown
- 1998-05-29 DE DE59810485T patent/DE59810485D1/de not_active Expired - Fee Related
- 1998-05-29 CN CN98806104A patent/CN1259954A/zh active Pending
- 1998-05-29 NZ NZ502237A patent/NZ502237A/en unknown
- 1998-05-29 US US09/445,178 patent/US6159981A/en not_active Expired - Lifetime
- 1998-05-29 JP JP50145999A patent/JP2002504104A/ja active Pending
- 1998-06-03 TW TW087108721A patent/TW479059B/zh not_active IP Right Cessation
- 1998-06-11 CO CO98033543A patent/CO4940481A1/es unknown
- 1998-06-11 AR ARP980102768A patent/AR014354A1/es not_active Application Discontinuation
- 1998-06-12 ZA ZA9805120A patent/ZA985120B/xx unknown
- 1998-06-12 HR HR19724979.5A patent/HRP980318A2/hr not_active Application Discontinuation
- 1998-06-13 MY MYPI98002644A patent/MY132993A/en unknown
-
1999
- 1999-11-24 BG BG103921A patent/BG103921A/xx unknown
- 1999-12-08 NO NO996045A patent/NO996045D0/no not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0329168A2 (de) * | 1988-02-18 | 1989-08-23 | Bristol-Myers Squibb Company | Psychotropische Heterobicycloalkylpiperazinderivate |
US4835157A (en) * | 1988-03-15 | 1989-05-30 | Ortho Pharmaceutical Corporation | Thieno- and furopyrimidine-2,4-dione piperidine derivatives as serotonin antagonists and alpha adrenergic blocking agents |
WO1998011110A1 (de) * | 1996-09-10 | 1998-03-19 | Basf Aktiengesellschaft | 3-substituierte pyrido [4',3':4,5] thieno [2,3-d]pyrimidin-derivate, ihre herstellung und verwendung |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6387912B1 (en) | 1999-01-11 | 2002-05-14 | Basf Aktiengesellschaft | Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia |
CN100370989C (zh) * | 1999-01-11 | 2008-02-27 | Basf公司 | 5-ht5配体在制备治疗神经变性疾病的药物中的应用 |
WO2002002569A1 (de) * | 2000-07-03 | 2002-01-10 | Abbott Gmbh & Co. Kg | Substituierte thienopyrimidin derivate und ihre verwendung zur prophylaxe und therapie der zerebralen ischämie |
WO2004055024A1 (de) * | 2002-12-18 | 2004-07-01 | Abbott Gmbh & Co. Kg | 3-substituierte 3,4-dihydro-thieno[2,3-d]pyrimidin-4-on-derivate, ihre herstellung und verwendung |
Also Published As
Publication number | Publication date |
---|---|
IL132985A0 (en) | 2001-03-19 |
HRP980318A2 (en) | 1999-04-30 |
KR20010013698A (ko) | 2001-02-26 |
SK174399A3 (en) | 2000-05-16 |
AU748697B2 (en) | 2002-06-13 |
TW479059B (en) | 2002-03-11 |
MY132993A (en) | 2007-10-31 |
ID24045A (id) | 2000-07-06 |
EP1023296B1 (de) | 2003-12-17 |
ATE256686T1 (de) | 2004-01-15 |
NZ502237A (en) | 2001-08-31 |
EP1023296A1 (de) | 2000-08-02 |
NO996045L (no) | 1999-12-08 |
CO4940481A1 (es) | 2000-07-24 |
CA2293440A1 (en) | 1998-12-17 |
HUP0002736A3 (en) | 2001-04-28 |
BG103921A (en) | 2000-07-31 |
BR9810008A (pt) | 2000-09-19 |
TR199903061T2 (xx) | 2000-07-21 |
AR014354A1 (es) | 2001-02-28 |
JP2002504104A (ja) | 2002-02-05 |
HUP0002736A2 (hu) | 2001-02-28 |
US6159981A (en) | 2000-12-12 |
DE59810485D1 (de) | 2004-01-29 |
AU8535798A (en) | 1998-12-30 |
ES2215312T3 (es) | 2004-10-01 |
CN1259954A (zh) | 2000-07-12 |
DE19724979A1 (de) | 1998-12-17 |
ZA985120B (en) | 1999-12-13 |
NO996045D0 (no) | 1999-12-08 |
PL337454A1 (en) | 2000-08-14 |
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