WO1998037191A1 - Plnh (peptide lymphocytaire neutrophile humain) circulant - Google Patents

Plnh (peptide lymphocytaire neutrophile humain) circulant Download PDF

Info

Publication number
WO1998037191A1
WO1998037191A1 PCT/EP1998/000950 EP9800950W WO9837191A1 WO 1998037191 A1 WO1998037191 A1 WO 1998037191A1 EP 9800950 W EP9800950 W EP 9800950W WO 9837191 A1 WO9837191 A1 WO 9837191A1
Authority
WO
WIPO (PCT)
Prior art keywords
hnlp
seq
polypeptide
amino acids
oligo
Prior art date
Application number
PCT/EP1998/000950
Other languages
German (de)
English (en)
Inventor
Wolf-Georg Forssmann
Burkhard Kleemeier
Peter Schulz-Knappe
Michael Nehls
Original Assignee
Forssmann Wolf Georg
Burkhard Kleemeier
Schulz Knappe Peter
Michael Nehls
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1997130786 external-priority patent/DE19730786C2/de
Application filed by Forssmann Wolf Georg, Burkhard Kleemeier, Schulz Knappe Peter, Michael Nehls filed Critical Forssmann Wolf Georg
Publication of WO1998037191A1 publication Critical patent/WO1998037191A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

L'invention a trait à un peptide de la formule (I): Ra-C-Xn-C-Rd, où Ra est NH2 ou un dérivé d'un groupe amine primaire, ou un oligopeptide ou polypeptide composé dans un cas comme dans l'autre d'acides aminés existant dans la nature, de leurs dérivés modifiés dans la chaîne latérale et/ou de leurs stéréo-isomères aminoacides; n est un entier entre 3 et 7; X est un acide aminé existant dans la nature, son dérivé modifié dans la chaîne latérale et/ou son stéréo-isomère aminoacide; et Rd est COOH, un dérivé d'acide carboxylique, ou un oligopeptide ou polypeptide composé dans un cas comme dans l'autre d'acides aminés existant dans la nature, de leurs dérivés modifiés dans la chaîne latérale et/ou de leurs stéréo-isomères.
PCT/EP1998/000950 1997-02-20 1998-02-19 Plnh (peptide lymphocytaire neutrophile humain) circulant WO1998037191A1 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE19706937 1997-02-20
DE19706937.1 1997-02-20
DE19712487.9 1997-03-25
DE19712487 1997-03-25
DE1997130786 DE19730786C2 (de) 1997-07-18 1997-07-18 Humanes zirkulierendes hNLP (humanes Neutrophilen-Lymphocyten-Peptid)
DE19730786.8 1997-07-18

Publications (1)

Publication Number Publication Date
WO1998037191A1 true WO1998037191A1 (fr) 1998-08-27

Family

ID=27217139

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/000950 WO1998037191A1 (fr) 1997-02-20 1998-02-19 Plnh (peptide lymphocytaire neutrophile humain) circulant

Country Status (1)

Country Link
WO (1) WO1998037191A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000029621A2 (fr) * 1998-11-16 2000-05-25 Genelabs Technologies, Inc. Methode pour mesurer des polynucleotides cibles et des biomolecules de l'asthme

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001436A1 (fr) * 1993-06-29 1995-01-12 The Salk Institute For Biological Studies Toxines de cone presentant des proprietes de liaison au recepteur d'acetylcholine
US5585478A (en) * 1992-12-10 1996-12-17 Beth Israel Hospital Association D4 gene and methods of use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5585478A (en) * 1992-12-10 1996-12-17 Beth Israel Hospital Association D4 gene and methods of use thereof
WO1995001436A1 (fr) * 1993-06-29 1995-01-12 The Salk Institute For Biological Studies Toxines de cone presentant des proprietes de liaison au recepteur d'acetylcholine

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
EMBL Datenbank Entry HS26447; Zugriffsnummer T82264; 28 März 1995; HILLIER L. ET AL.:"The WashU-Merck EST project" *
EMBL Datenbank entry HS46277; Zugriffsnummer R11462; 21 April 1995; HILLIER L. ET AL.:"The WashU-Merck EST project" *
EMBL Datenbank Entry HS52831; Zugriffsnummer T60528; 5 März 1995; HILLIER L. ET AL.:"The WashU-Merck EST project" *
EMBL Datenbank Entry HS551134; Zugriffsnummer T83551; 31 Mai 1995 HILLIER L. ET AL.:"The WashU-Merck EST project" *
EMBL Datenbank Entry MM16134; Zugriffsnummer W82161; 27 Juni 1996; MARRA M. ET AL.:"The WashU-HHMI Mouse EST project" *
EMBL Datenbank Entry MM82512; Zugriffsnummer W29825; 10 Mai 1996; MARRA M. ET AL.:"The WashU-HHMI Mouse EST project" *
ROBERT I. LEHRER ET AL.: "Defensins: Endogenous antibiotic peptides of animal cells", CELL, vol. 64, no. 2, 25 January 1991 (1991-01-25), NA US, pages 229 - 230, XP000170612 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000029621A2 (fr) * 1998-11-16 2000-05-25 Genelabs Technologies, Inc. Methode pour mesurer des polynucleotides cibles et des biomolecules de l'asthme
WO2000029621A3 (fr) * 1998-11-16 2000-11-09 Genelabs Tech Inc Methode pour mesurer des polynucleotides cibles et des biomolecules de l'asthme

Similar Documents

Publication Publication Date Title
DE69531892T2 (de) Fibroblasten-wachstumsfaktor 10
DE69636752T2 (de) Menschlicher wachstumsfaktor 2, spezifisch für vaskuläre endothelzellen
DE69133591T2 (de) CNP-Gen und Vorläuferprotein aus Schwein
WO1996001316A1 (fr) NOUVEAU FACTEUR DE CROISSANCE/DIFFERENCIATION DE LA FAMILLE DU TGF-$g(b)
EP0393438A2 (fr) Récepteur du TNF, protéine liant le TNF at ADN codant pour ceux-ci
DE19757250A1 (de) Insulin-like growth factor binding protein und seine Verwendung
EP0736095B1 (fr) Cytokine humaine circulante cc-1
DE69835777T2 (de) 5' EST's für sekretierte Proteine, die in verschiedenen Geweben exprimiert werden
DE69532874T2 (de) RPDL Protein und kodierende DNS
DE69837507T2 (de) Humanes Hedgehog-Protein
DE69233155T2 (de) Insulinartigen wachstumsfaktor bindendes protein
EP1959013B1 (fr) Peptide inhibiteur de virus humain (VIRIP) et son utilisation
EP1287142B1 (fr) Molecule d'acide nucleique contenant une sequence d'acide nucleique codant pour une chimiokine sdf-1 gamma, un precurseur neuropeptidique ou au moins un neuropeptide
EP0616642B1 (fr) Nouvelles proteines inhibitrices de thrombine provenant de la sangsue des campagnes
EP1007671B1 (fr) Gene ii de fanconi
WO1998037191A1 (fr) Plnh (peptide lymphocytaire neutrophile humain) circulant
DE19730786C2 (de) Humanes zirkulierendes hNLP (humanes Neutrophilen-Lymphocyten-Peptid)
DE69836278T2 (de) Allele formen von menschlichem stat3
DE69728436T9 (de) Leptin-protein aus schwein, dafür kodierende nukleinsäuren und verwendungen davon
WO1997020049A1 (fr) Peptide humain circulant dans le sang et possedant un effet insulinotrope
DE4427531A1 (de) Humanes zirkulierendes beta-Defensin hBD-1
DE69832447T2 (de) Gen kodierend für Afadin-1
DE4344397A1 (de) Humanes zirkulierendes Cytokin CC-1
DE4427395A1 (de) Humanes zirkulierendes Cytokin CC-1
DE69835526T2 (de) Östrogenrezeptor

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: JP

Ref document number: 1998536250

Format of ref document f/p: F

122 Ep: pct application non-entry in european phase