WO1998008482A3 - Inhibition de l'agregation plaquettaire dans du sang expose a un corps etranger au moyen d'un enrobage polymere recouvrant la surface dudit corps et comportant un compose organometallique contenant du nitrosyle et liberant de l'oxyde nitrique, et corps etrangers ainsi enrobes - Google Patents
Inhibition de l'agregation plaquettaire dans du sang expose a un corps etranger au moyen d'un enrobage polymere recouvrant la surface dudit corps et comportant un compose organometallique contenant du nitrosyle et liberant de l'oxyde nitrique, et corps etrangers ainsi enrobes Download PDFInfo
- Publication number
- WO1998008482A3 WO1998008482A3 PCT/US1997/015022 US9715022W WO9808482A3 WO 1998008482 A3 WO1998008482 A3 WO 1998008482A3 US 9715022 W US9715022 W US 9715022W WO 9808482 A3 WO9808482 A3 WO 9808482A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- coating
- blood
- platelet aggregation
- foreign body
- aggregation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/02—Use of inorganic materials
- A61L33/027—Other specific inorganic materials not covered by A61L33/022 or A61L33/025
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
- A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
- Y10S623/924—Material characteristic
- Y10S623/926—Synthetic
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Inorganic Chemistry (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL12873997A IL128739A (en) | 1996-08-27 | 1997-08-27 | Inhibition of blood platelet aggregation |
US09/254,002 US6656217B1 (en) | 1996-08-27 | 1997-08-27 | Medical device coated with a polymer containing a nitric oxide releasing organometallic nitrosyl compound useful for the prevention of platelet aggregation |
NZ334392A NZ334392A (en) | 1996-08-27 | 1997-08-27 | Device with polymeric coating containing a nitrosyl-containing organometallic compound which releases nitric oxide and inhibits platelet aggregation |
JP10511854A JP2001501104A (ja) | 1996-08-27 | 1997-08-27 | その表面を、酸化窒素放出ニトロシル含有有機金属化合物でコートされたポリマーによる、外来物に曝された血液血小板凝固の阻害およびこのようにコートされた外来物 |
CA002264564A CA2264564A1 (fr) | 1996-08-27 | 1997-08-27 | Inhibition de l'agregation plaquettaire dans du sang expose a un corps etranger au moyen d'un enrobage polymere recouvrant la surface dudit corps et comportant un compose organometallique contenant du nitrosyle et liberant de l'oxyde nitrique, et corps etrangers ainsi enrobes |
EP97939571A EP0975274A4 (fr) | 1996-08-27 | 1997-08-27 | Inhibition de l'agregation plaquettaire dans du sang expose a un corps etranger au moyen d'un enrobage polymere recouvrant la surface dudit corps et comportant un compose organometallique contenant du nitrosyle et liberant de l'oxyde nitrique, et corps etrangers ainsi enrobes |
AU41632/97A AU733616B2 (en) | 1996-08-27 | 1997-08-27 | Device coated with a polymer containing a nitric oxide releasing organometallic nitrosyl compound useful for the prevention of platelet aggregation |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/703,646 | 1996-08-27 | ||
US08/703,646 US5797887A (en) | 1996-08-27 | 1996-08-27 | Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/254,002 A-371-Of-International US6656217B1 (en) | 1996-08-27 | 1997-08-27 | Medical device coated with a polymer containing a nitric oxide releasing organometallic nitrosyl compound useful for the prevention of platelet aggregation |
US10/291,753 Continuation-In-Part US20030093143A1 (en) | 1996-08-27 | 2002-11-12 | Medical device having surface depressions containing nitric oxide releasing compound |
Publications (3)
Publication Number | Publication Date |
---|---|
WO1998008482A2 WO1998008482A2 (fr) | 1998-03-05 |
WO1998008482A3 true WO1998008482A3 (fr) | 1998-04-23 |
WO1998008482B1 WO1998008482B1 (fr) | 1998-06-11 |
Family
ID=24826237
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/015022 WO1998008482A2 (fr) | 1996-08-27 | 1997-08-27 | Inhibition de l'agregation plaquettaire dans du sang expose a un corps etranger au moyen d'un enrobage polymere recouvrant la surface dudit corps et comportant un compose organometallique contenant du nitrosyle et liberant de l'oxyde nitrique, et corps etrangers ainsi enrobes |
Country Status (8)
Country | Link |
---|---|
US (2) | US5797887A (fr) |
EP (1) | EP0975274A4 (fr) |
JP (1) | JP2001501104A (fr) |
AU (1) | AU733616B2 (fr) |
CA (1) | CA2264564A1 (fr) |
IL (1) | IL128739A (fr) |
NZ (1) | NZ334392A (fr) |
WO (1) | WO1998008482A2 (fr) |
Cited By (4)
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US8282967B2 (en) | 2005-05-27 | 2012-10-09 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications |
US8591876B2 (en) | 2010-12-15 | 2013-11-26 | Novan, Inc. | Methods of decreasing sebum production in the skin |
US8981139B2 (en) | 2011-02-28 | 2015-03-17 | The University Of North Carolina At Chapel Hill | Tertiary S-nitrosothiol-modified nitric—oxide-releasing xerogels and methods of using the same |
US9526738B2 (en) | 2009-08-21 | 2016-12-27 | Novan, Inc. | Topical gels and methods of using the same |
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Also Published As
Publication number | Publication date |
---|---|
US5797887A (en) | 1998-08-25 |
AU733616B2 (en) | 2001-05-17 |
AU4163297A (en) | 1998-03-19 |
WO1998008482A2 (fr) | 1998-03-05 |
CA2264564A1 (fr) | 1998-03-05 |
JP2001501104A (ja) | 2001-01-30 |
EP0975274A2 (fr) | 2000-02-02 |
NZ334392A (en) | 2000-11-24 |
EP0975274A4 (fr) | 2004-05-19 |
US6656217B1 (en) | 2003-12-02 |
IL128739A (en) | 2004-06-01 |
IL128739A0 (en) | 2000-01-31 |
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