WO1992015206A1 - Composition en poudre, procede de preparation et methode permettant d'ameliorer la saveur de celle-ci - Google Patents

Composition en poudre, procede de preparation et methode permettant d'ameliorer la saveur de celle-ci Download PDF

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Publication number
WO1992015206A1
WO1992015206A1 PCT/FI1992/000061 FI9200061W WO9215206A1 WO 1992015206 A1 WO1992015206 A1 WO 1992015206A1 FI 9200061 W FI9200061 W FI 9200061W WO 9215206 A1 WO9215206 A1 WO 9215206A1
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WO
WIPO (PCT)
Prior art keywords
weight
composition
approx
composition according
acid
Prior art date
Application number
PCT/FI1992/000061
Other languages
English (en)
Inventor
Lasse Kurppa
Original Assignee
Rabbe Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rabbe Oy filed Critical Rabbe Oy
Publication of WO1992015206A1 publication Critical patent/WO1992015206A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/385Concentrates of non-alcoholic beverages
    • A23L2/39Dry compositions
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/10Natural spices, flavouring agents or condiments; Extracts thereof
    • A23L27/14Dried spices
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/40Table salts; Dietetic salt substitutes
    • A23L27/45Salt substitutes completely devoid of sodium chloride
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana

Definitions

  • the present invention relates to a substantially sodiu - free pulverous composition which can be used as a mineral preparation and has in particular an improved taste on account of which the said composition can be used as a drink powder.
  • the diuretics used for the treatment of hypertension remove both potassium and magnesium from the human body, and therefore, especially during conventional drug treatment of hypertension, it is important to receive natural supplements.
  • potassium chloride has certain harmful side effects. Efforts have been made to eliminate the harmful effects on the gastrointestinal tract (ulcerogenic effect) during potassium substitution therapy by using so-called enteric-coated potassium chloride tablets. By this, mainly two objectives are aimed at, i.e. first, to elim ⁇ inate the objectionable and bitter taste of potassium chloride by the coating, and second, to make sure that the tablet will travel to where its absorption mainly takes place and at the same time the accumulation of local potassium chloride contents in the stomach is prevented.
  • Enteric-coated tablets release the potassium chloride rapidly upon arriving in the small intestine, and as a consequence they may cause in the small intestine local ulceration, bleeding, constriction, even necroses and perforation of the small intestine. Similar symptoms have been observed even during the use of slowly released potassium chloride tablets.
  • FI patent application 885662 discloses a composition which is used as a natural-food product and a food additive, and contains potassium chloride approx. 65 %, magnesium sulfate approx. 28 %, and additionally a compound which yields hydrogen ions and is preferably composed of lysine hydro- chloride, citric acid, glutamic acid and ascorbic acid.
  • Antisalt R preparation has been made into pellets, which are ingested orally. These pellets have the disadvantage that their taste is objectionable and bitter. Owing to their high potassium chloride concentration these pellets may have on the gastrointestinal tract harmful effects similar to those of the above-described potassium chloride tablets used in potassium substitution therapy, especially if their intake is considerably greater than indicated in the dosing instructions (2-3 pellets) .
  • the object of the invention is to provide a product with which the above-mentioned disadvantages of the Antisalt R preparation known from FI patent application 885662 are avoided, and in particular to provide a potassium- and magnesium-containing drink powder which has an improved taste and has no harmful side effects in the gastroin ⁇ testinal tract.
  • the invention thus relates to a substantially sodium-free pulverous product usable as a mineral preparation, which contains a potassium compound and a magnesium compound and an organic carboxylic acid, the molar ratio Mg:K in the composition being within a range of approx. 1:5-1:11, the composition being characterized in that it additionally contains Gentianae powder as a taste-improving ingredient at approx. 0.01-0.5 % by weight, calculated from the total weight of the powder.
  • Gentianae powder is prepared by evaporating the solvent and water from an extract or tincture prepared fro dried roots of plants of the Gentianae family. Gentianae powder completely masks the objectionable and bitter taste of potassium chloride, and additionally it increases the secretion of saliva and stimulates the appetite.
  • the composition according to the invention preferably contains a potassium salt, in particular potassium chloride, the amount of which is preferably 44-65 % by weight, calculated from the total weight of the composition.
  • the composition according to the invention preferably contains magnesium sulfate, magnesium oxide or magnesium carbonate, and most preferably magnesium sulfate heptahydrate, the amount of which is preferably 19- 28 % by weight, calculated from the total weight of the composition.
  • composition according to the invention contains preferably an organic carboxylic acid approx. 0.5-7 % by weight, and most preferably tartaric acid approx. 3-5 % by weight, citric acid- 0.4-0.6 % by weight, and ascorbic acid 0.1-0.3 % by weight.
  • composition according to the invention may additionally contain an amino acid approx. 0.5-2 % by weight, lysine hydrochloride 0.8-1.2 % by weight, and glutamic acid 0.1- 0.3 % by weight.
  • organic carboxylic acids and amino acids serve in the composition as proton-yielding ingredients.
  • composition according to the invention may additionally contain other physiologically acceptable ingredients, such as excipients, of which macrocrystalline cellulose can be mentioned.
  • excipients of which macrocrystalline cellulose can be mentioned.
  • the amount of excipients may be, for example, approx. 10-20 % by weight.
  • composition according to the invention is prepared in a conventional manner by dry-blending the ingredients to form a homogenous drink powder.
  • the drink powder according to the invention is preferably packed in single-dose sachets.
  • the contents of a sachet are stirred into a glass of water and ingested before a meal.
  • Gentianae powder Water and alcohol are evaporated out from Gentianae tincture to produce Gentianae powder.
  • Drink powder is prepared from the following pulverous in ⁇ gredients (percentage amounts of ingredients are indicated in parentheses) :
  • Lysine hydrochloride 18.00 mg (1.0 %)
  • Gentianae powder 1.80 mg (0.1 %) Gentianae powder is blended with tartaric acid, and this mixture is then blended with the other ingredients to produce a drink powder.
  • the molar ratio Mg:K is approx. 1:8.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention se rapporte à une poudre pour boisson ne contenant pas de sodium, utilisable comme préparation minérale. La poudre contient un composé de potassium ainsi qu'un composé de magnésium, le rapport molaire Mg:K pouvant aller de 1:5 à 1:11. De plus, elle contient de l'acide carboxylique organique et éventuellement un acide aminé ainsi qu'une poudre de Gentianae comme ingrédient destiné à améliorer la saveur, en une quantité d'environ 0.01-0-5 % en poids, calculée à partir du poids total de la composition.
PCT/FI1992/000061 1991-03-01 1992-03-02 Composition en poudre, procede de preparation et methode permettant d'ameliorer la saveur de celle-ci WO1992015206A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI911038 1991-03-01
FI911038A FI911038A (fi) 1991-03-01 1991-03-01 Dryckpulver.

Publications (1)

Publication Number Publication Date
WO1992015206A1 true WO1992015206A1 (fr) 1992-09-17

Family

ID=8532027

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FI1992/000061 WO1992015206A1 (fr) 1991-03-01 1992-03-02 Composition en poudre, procede de preparation et methode permettant d'ameliorer la saveur de celle-ci

Country Status (3)

Country Link
AU (1) AU1355792A (fr)
FI (1) FI911038A (fr)
WO (1) WO1992015206A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999011149A1 (fr) * 1997-08-30 1999-03-11 All Sun Hsf Company Limited Composition servant a soulager l'agression thermique
US7001612B2 (en) 1998-08-26 2006-02-21 All Sun Hsf Company Limited Composition for the relief of heat stress
WO2006066716A1 (fr) * 2004-12-23 2006-06-29 Unilever N.V. Renforceur de gout
ES2302576A1 (es) * 2005-06-13 2008-07-16 Mercadalia, S.L. Una composicion dietetica sustitutiva de la sal de mesa.

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4219579A (en) * 1979-01-25 1980-08-26 Carl Piampiano Means and method improving taste of saccharine sweetened food products
WO1985002324A1 (fr) * 1983-11-24 1985-06-06 Pharmaconsult Oy Melange de sels et utilisations du melange
DE3830563A1 (de) * 1987-09-11 1989-03-30 Ciba Geigy Ag Orale magnesium und kalium enthaltende praeparate und deren verwendung
EP0377119A1 (fr) * 1988-12-07 1990-07-11 Selako Oy Agent pour la réduction d'effets désavantageuses de sel de table

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4219579A (en) * 1979-01-25 1980-08-26 Carl Piampiano Means and method improving taste of saccharine sweetened food products
WO1985002324A1 (fr) * 1983-11-24 1985-06-06 Pharmaconsult Oy Melange de sels et utilisations du melange
DE3830563A1 (de) * 1987-09-11 1989-03-30 Ciba Geigy Ag Orale magnesium und kalium enthaltende praeparate und deren verwendung
EP0377119A1 (fr) * 1988-12-07 1990-07-11 Selako Oy Agent pour la réduction d'effets désavantageuses de sel de table

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999011149A1 (fr) * 1997-08-30 1999-03-11 All Sun Hsf Company Limited Composition servant a soulager l'agression thermique
US7001612B2 (en) 1998-08-26 2006-02-21 All Sun Hsf Company Limited Composition for the relief of heat stress
WO2006066716A1 (fr) * 2004-12-23 2006-06-29 Unilever N.V. Renforceur de gout
ES2302576A1 (es) * 2005-06-13 2008-07-16 Mercadalia, S.L. Una composicion dietetica sustitutiva de la sal de mesa.

Also Published As

Publication number Publication date
FI911038A (fi) 1992-09-02
AU1355792A (en) 1992-10-06
FI911038A0 (fi) 1991-03-01

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