WO1990004429A2 - Adhesive dressing for intravenous peripheral cannulas - Google Patents

Adhesive dressing for intravenous peripheral cannulas Download PDF

Info

Publication number
WO1990004429A2
WO1990004429A2 PCT/EP1989/001273 EP8901273W WO9004429A2 WO 1990004429 A2 WO1990004429 A2 WO 1990004429A2 EP 8901273 W EP8901273 W EP 8901273W WO 9004429 A2 WO9004429 A2 WO 9004429A2
Authority
WO
WIPO (PCT)
Prior art keywords
adhesive dressing
adhesive
characterized
cannulas
recess
Prior art date
Application number
PCT/EP1989/001273
Other languages
German (de)
French (fr)
Other versions
WO1990004429A3 (en
Inventor
H. T. Khawaja
Original Assignee
Pfrimmer Kabi Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE19883836828 priority Critical patent/DE3836828A1/en
Priority to DEP3836828.5 priority
Application filed by Pfrimmer Kabi Gmbh & Co Kg filed Critical Pfrimmer Kabi Gmbh & Co Kg
Publication of WO1990004429A2 publication Critical patent/WO1990004429A2/en
Publication of WO1990004429A3 publication Critical patent/WO1990004429A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/02Holding devices, e.g. on the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/02Holding devices, e.g. on the body
    • A61M2025/0266Holding devices, e.g. on the body using pads, patches, tapes or the like
    • A61M2025/0273Holding devices, e.g. on the body using pads, patches, tapes or the like having slits to place the pad around a catheter puncturing site

Abstract

Adhesive dressing for intravenous peripheral cannulas made from a microporous material (1), with a recess (2) into which the cannula (4) fits, characterized in that it has an anti-inflammatory substance on the skin side. Also described is the use of glyceryle trinitrate in adhesive dressings for intravenous peripheral cannulas for prophylaxis of thrombophlebitis.

Description

Adhesive dressing for intravenous peripheral cannulas

The invention relates to an adhesive dressing for intravenous cannulas peri¬ phere of a microporous material having a Ausspa¬ tion for receiving the cannula.

Adhesive dressings of the above type are known. They are used for fixation of venous catheters, which are used for a long time and are also intended to cover the injection site sterile and protect against the entry of microorganisms and prevent the occurrence of phlebitis and other complications. For the longer-term and long-term venous Katherisierungen also should be gewährlei¬ stet of permanently correct seating of the catheter. Such HaftverbMnde material must be permeable to sweat and oxygen-and at the same time prevent the penetration of Flüssigkei¬ th.

It is also known to make such adhesion associations partially transpa¬ rent to control the injection site and the right positioning of Katheters-.

In the conventional adhesive dressings for intravenous peripheral cannulas but there is a problem particularly prevalent during länger¬ term Kathetisierungen injection site inflammation, for example, a thrombophlebitis. inflammations such Ent need of treatment, which requires the removal of the catheter and applying a new sierungsstelle at another Katheti-. This is undesirable for medical reasons and, besides being time-consuming and cost-εtenintensiv and uncomfortable for the patient. There is therefore a need for pressure-sensitive associated the intravenö¬ se for peripheral cannulas, with which the Plebitiεriεiko can be significantly reduced. Such HaftverbMnde are also intended to ensure a tight fit of the venous catheter, his sweat and sauerεtoffdurchlSssig, prevent the entry of microorganisms and fluids, be kind to the skin even during extended residence time and also easy and safe to handle and washable labeled.

This object is achieved with the adhesives of the initially associated the geschilder¬ th type which are characterized in that they contain an anti-inflammatory substance on its skin side.

Preferably, a trans- derma] is used acting agent as anti-inflammatory substance, such as glyceryl trinitrate and / or NSAID = non-steroidal-Z ^ iiππanrβtory-drugs, non-steroidal entzi jπgsh β πrende means GTN has surprisingly in Thrombophlebitiε-the prophylaxis as proven very effective. It is slowly absorbed through the skin and spreads in the Auftragungsstel¬ le and the surrounding area its anti-inflammatory effect. When using GTN in the adhesive dressings Phlebitiεriεi- ko εtark decreases, and the residence time of the adhesive dressings and peripheral intravenous cannulas can be significantly prolonged.

The amounts required of the active ingredient in the range of 1, biε 10 mg / d, preferably 3 biε 7 mg / d; Trains t beεonders bevor¬ is an amount in the range of 5 mg nitroglycerin / d.

The anti-inflammatory substance is vorzugswei¬ in adhesive dressing se in the vicinity of the injection site disposed. However, due to over the pad out 'effect occurring tranεdeπnaler substances, it is not necessary that the Einstichstel¬ le is covered directly; this is also undesirable hSufig to seepage of the agent into the puncture site or Be¬ einträchtigung its effectiveness by liquid emerging therefrom or to prevent secretions. but the anti-inflammatory substance may be disposed of or at multiple discrete locations also over the entire range of Haftverban¬. Preferably, the anti-inflammatory substance is applied to the skin-facing material of the adhesive dressing or is present on or in a carrier disposed on the inside; but it can even be enthal¬ th in the material of the adhesive bandage if the controlled delivery to the skin is gewährlei¬ stet. Measures to control the rate of delivery of transdermally active Subtanz are known in the art. If necessary, the anti-inflammatory is Sustanz by a barrier layer, such as a common use for this impermeable film, secured against passage through the adhesive dressing to the outside.

The adhesive dressing according to the invention is suitable for all forms herkömm¬ Licher needles for intravenous use peripheral geeig¬ net, so for example, butterfly wings or cannulas, but also for wingless needles and cannulas with Zuspritz- valves. As material for the adhesive dressing used conventional welding and oxygen-permeable materials, stitch make sure cover Ein¬ and organisms against the penetration of liquids and to protect Mikro¬. For this purpose, especially hypoallergenic microporous films are suitable materials, for example, urethane-based, or based on polymeric fluorinated Kohlenwasser¬.

Preferably, the adhesive dressing of the invention contains TERIAL in its central region, ie over the puncture site of the needle, a transparent panel or window of a customary for this purpose ma- such as OpSite by which a control of Einεtichstelle any time. This allows häu¬-stage dressing changes, which serve only to control, prevent and the risk of infection is reduced.

The recess in the adhesive dressing, such as in the form of a u-shaped cut, facilitating the fixation of conventional Flü¬ gelkanülen by the two side wings are pushed under the recess adjacent to the adhesive bandage parts.

According to another embodiment of the adhesive bandage in Be¬ is equipped nülen rich this recess with a holder for wingless Ka. This support is in the form of adhesive strips which surround the inserted cannula above and below sandwichar¬ tig and fix to the the recess delimiting sides of the microporous material. This adhesive Haftstrei¬ fen jump out from both sides of the recess-limiting adhesive dressing and parts are on facing Sei¬ th adhesively coated. They should be long enough that it from the side of the adhesion Association from from which they emanate, reached via the cannula and recess, the opposite side of the pressure sensitive adhesive Association and can be fixed there. The holder guarantees a firm connection of the cannula with the two sides of the adhesive dressing, the savings are adjacent to the Aus¬. In general, a pair of opposed adhesive stripe is present in the region of the recess, but there may be two or more adhesive strip pairs may be present.

The invention is explained by the accompanying drawings erläu¬, of which

Fig. 1 is an adhesive dressing according to the invention according to an embodiment be¬ vorzugten with transparent windows and

Fig. 2 a strip-adhesive dressing with a transparent window, and show Haft¬ attached needle.

The adhesive dressing according to Fig. 1 consists of the micro- or milli- poröεen non-tranεparenten material 1 with the Auεsparung 2 and the window of the transparent material 3. The cannula is in the region of the recess 2 is inserted in and penetrates through the window rich Be¬ 3 skin. It is held by either wing, attached to the recess 2 angrenze the parts 7 of the material 1 are pushed and fixed adhesively or via normal adhesive strip outside the adhesion promoter bändbereiches adhered to the skin under the two. The corners of the Haftverban are rounded to an unintentional detachment of the Haftverban to aggravate the skin in the region of the corners or prevent. The antiinflammatory material (not visible) arranged on the underside in the region of the porous material 1 of the adhesive dressing.

Fig. 2 shows another embodiment of the adhesive dressing according to the invention from the opaque microporous material 1 with the recess 2, the transparent window area 3 and an inserted cannula 4. The cannula 4 is in the region of the recess 2 by adhesive strips 5, 5 ', to two Sei¬ th of the recess 2 of the adjacent sides of the material 1 protrude adhesively retained, wherein a strip 5, the recess 2 bridges on one side of the cannula and the strip 5 'on the opposite side (in the revealed Fig.l ver) so that the cannula sandwiched by the two patrol and is fixed to the adjacent sides 7 of the Haftverban.

The adhesive dressing has in the region of the window 3 to an area in which the anti-inflammatory agent is arranged. Al¬ ternatively the anti-inflammatory agent may Chen also in the areas 6 'or 6' 'can be arranged, for example in the form of coated with GTN bodies or supports, which are optionally secured by a barrier material against a passage of the substance through the adhesive dressing to the outside.

The adhesive dressings of the invention have the usual Abmessun gene, for example, about 75 x 120 mm with a Fenεtergrδße vo 55 x 45 mm and located towards the center tapering Ausspa¬ delay of 10 mm width and 75 mm initial length. but these dimensions may vary and depending on the application, spielsweise for children, be significantly less.

Claims

P atentanspr u ch
1. Adhesive dressing for intravenous, peripheral cannulas of a microporous material (1) with a recess (2) for Aufna of the cannula (4), characterized in that said adhesive dressing having on its skin side a entzündungshemm de substance.
2. An adhesive dressing according to claim 1, characterized in that the anti-inflammatory substance is a substance transdermally act.
3. An adhesive dressing according to claim 2, characterized in that the anti-inflammatory substance is glyceryl trinitrate.
4. An adhesive dressing according to any one of claims 1 to 3, characterized in that the anti-inflammatory agent in the area of ​​steep espe is arranged the cannula.
5. An adhesive dressing according to any of Anεprüche 1 to 4, characterized in that a transparent window (3) is applied in its central region above the puncture site of the needle (4).
6. An adhesive dressing according to any one of claims 1 to 5, characterized in that in the region of the recess (2) a bracket (5) for flü¬ gellose cannulas (4) is present.
7. An adhesive dressing according to claim 6, characterized in that the holder in the form of adhesive strips (5, 5 ') which from both sides of the recess (2) jump overlapping each other in front, wherein the adhesive sides facing each other, and the cannula close (4) from above and from below sandwiched ein¬ and fix to the sides of the adhesive dressing.
8. The use of glyceryl trinitrate in custody associations for intr venous, peripheral cannulae for the prevention of thrombophlebitis
PCT/EP1989/001273 1988-10-28 1989-10-25 Adhesive dressing for intravenous peripheral cannulas WO1990004429A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE19883836828 DE3836828A1 (en) 1988-10-28 1988-10-28 Adhesive dressing for intravenous peripheral cannulas
DEP3836828.5 1988-10-28

Publications (2)

Publication Number Publication Date
WO1990004429A2 true WO1990004429A2 (en) 1990-05-03
WO1990004429A3 WO1990004429A3 (en) 1990-06-14

Family

ID=6366136

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1989/001273 WO1990004429A2 (en) 1988-10-28 1989-10-25 Adhesive dressing for intravenous peripheral cannulas

Country Status (4)

Country Link
EP (1) EP0446217A1 (en)
JP (1) JPH04501371A (en)
DE (1) DE3836828A1 (en)
WO (1) WO1990004429A2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992012757A1 (en) * 1991-01-25 1992-08-06 Lic Hygien Ab A windowed vein catheter dressing
EP0515807A1 (en) * 1991-05-27 1992-12-02 Beiersdorf Aktiengesellschaft Adhesive dressing for intravenous catheter
EP0780138A1 (en) * 1995-12-22 1997-06-25 Becton Dickinson and Company Medical device for the protection of a catheter penetration site
EP0797965A1 (en) * 1990-06-14 1997-10-01 Vitaphore Corporation Wound dressing and catheter securing using a polyurethane-biopolymer composite
US5833665A (en) * 1990-06-14 1998-11-10 Integra Lifesciences I, Ltd. Polyurethane-biopolymer composite

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE9103742U1 (en) * 1991-03-27 1991-06-13 Lohmann Gmbh & Co Kg, 5450 Neuwied, De

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2748882A1 (en) * 1977-11-02 1979-05-03 Arnis Dr Med Rava Plaster protecting wound against infection - esp. during application of intravenous catheter, permitting continuous use for ten days
US4297995A (en) * 1980-06-03 1981-11-03 Key Pharmaceuticals, Inc. Bandage containing attachment post
US4449975A (en) * 1981-11-09 1984-05-22 Perry Michael K Intravenous anchor and wound shield
US4534762A (en) * 1982-12-27 1985-08-13 Heyer Hal B Vascular puncture dressing
EP0284219A2 (en) * 1987-03-14 1988-09-28 Smith & Nephew plc Adhesive dressings, their preparation and use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3683911A (en) * 1970-08-13 1972-08-15 Pelam Inc Protective seal for catheter
DE2901302A1 (en) * 1979-01-15 1980-07-24 Battelle Institut E V Permanent catheter - seals puncture against infection by rubber sheath on catheter hose
DE2922347A1 (en) * 1979-06-01 1980-12-11 Klaus J Prof Dr Ing Huettinger Antimicrobial surface treatment of materials - by covalent coupling with antimicrobial agent
DE3129931C2 (en) * 1981-07-29 1983-10-13 Institut Fuer Wissenschaftliche Photographie Und Kinematographie Willi Fischer, 1000 Berlin, De

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2748882A1 (en) * 1977-11-02 1979-05-03 Arnis Dr Med Rava Plaster protecting wound against infection - esp. during application of intravenous catheter, permitting continuous use for ten days
US4297995A (en) * 1980-06-03 1981-11-03 Key Pharmaceuticals, Inc. Bandage containing attachment post
US4449975A (en) * 1981-11-09 1984-05-22 Perry Michael K Intravenous anchor and wound shield
US4534762A (en) * 1982-12-27 1985-08-13 Heyer Hal B Vascular puncture dressing
EP0284219A2 (en) * 1987-03-14 1988-09-28 Smith & Nephew plc Adhesive dressings, their preparation and use

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071447A (en) * 1990-06-14 2000-06-06 Integra Lifescineces I, Ltd. Method of making a polyurethane-biopolymer composite
US6596293B1 (en) 1990-06-14 2003-07-22 Integra Lifesciences I, Ltd. Polyurethane-biopolymer composite
EP0797965A1 (en) * 1990-06-14 1997-10-01 Vitaphore Corporation Wound dressing and catheter securing using a polyurethane-biopolymer composite
US5833665A (en) * 1990-06-14 1998-11-10 Integra Lifesciences I, Ltd. Polyurethane-biopolymer composite
US5380294A (en) * 1991-01-25 1995-01-10 Procter & Gamble Hygien Aktiebolag Windowed vein catheter dressing
WO1992012757A1 (en) * 1991-01-25 1992-08-06 Lic Hygien Ab A windowed vein catheter dressing
EP0515807A1 (en) * 1991-05-27 1992-12-02 Beiersdorf Aktiengesellschaft Adhesive dressing for intravenous catheter
EP0780138A1 (en) * 1995-12-22 1997-06-25 Becton Dickinson and Company Medical device for the protection of a catheter penetration site

Also Published As

Publication number Publication date
EP0446217A1 (en) 1991-09-18
JPH04501371A (en) 1992-03-12
WO1990004429A3 (en) 1990-06-14
DE3836828A1 (en) 1990-05-03

Similar Documents

Publication Publication Date Title
US4988341A (en) Sterilizing dressing device and method for skin puncture
CA1288304C (en) Protective catheter sleeve
US5015228A (en) Sterilizing dressing device and method for skin puncture
US8153394B2 (en) Apparatus and method for detecting bacterial growth beneath a wound dressing
EP1303239B1 (en) A dressing
US5336219A (en) Skin closure system
US5569207A (en) Hydrocolloid dressing
ES2227542T3 (en) hemostatic patch.
EP0396274B1 (en) Improvements in skin closure devices
US5000741A (en) Transparent tracheostomy tube dressing
US6350339B1 (en) Non-stretching wound dressing and method for making same
AU2005215776B2 (en) Adhesive-containing wound closure device and method
EP0259136B1 (en) Transdermal delivery device having a rate controlling adhesive
US6375639B1 (en) Intravenous stabilizing device
US4743231A (en) Drug administration needle unit
US20100318052A1 (en) Conformable medical dressing with self supporting substrate
US5302395A (en) Method and systems for administering nitroglycerin transdermally at enhanced transdermal fluxes
US3053255A (en) Process of percutaneously administering exact doses of physiologically active agents and composite unit therefor
DE69531104T2 (en) Transdermal system skin for administration by entepithelisierte
AU616535B2 (en) Adhesive sheet
US20040058994A1 (en) Local prevention or amelioration of pain from surgically closed wounds
DE69826484T3 (en) Improved dressing
EP1213037A1 (en) Methods and devices for facilitated non-invasive oxygen monitoring
CA1338779C (en) Method for treating pain associated with herpes-zoster and post-herpetic neuralgia by topical application of local anesthetics
US5736154A (en) Transdermal delivery system

Legal Events

Date Code Title Description
AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE FR GB IT LU NL SE

AK Designated states

Kind code of ref document: A2

Designated state(s): JP US

AK Designated states

Kind code of ref document: A3

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE FR GB IT LU NL SE

WWE Wipo information: entry into national phase

Ref document number: 1989912237

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1989912237

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1989912237

Country of ref document: EP