Classifications

• • C—CHEMISTRY; METALLURGY
  • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
  • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
  • C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
  • C08J5/12—Bonding of a preformed macromolecular material to the same or other solid material such as metal, glass, leather, e.g. using adhesives
  • C08J5/122—Bonding of a preformed macromolecular material to the same or other solid material such as metal, glass, leather, e.g. using adhesives using low molecular chemically inert solvents, swelling or softening agents
• • C—CHEMISTRY; METALLURGY
  • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
  • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
  • C08J2327/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Derivatives of such polymers
  • C08J2327/02—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Derivatives of such polymers not modified by chemical after-treatment
  • C08J2327/04—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Derivatives of such polymers not modified by chemical after-treatment containing chlorine atoms
  • C08J2327/06—Homopolymers or copolymers of vinyl chloride
• • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
  • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
  • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
  • Y10S128/00—Surgery
  • Y10S128/24—Medical-surgical bags
• • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
  • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
  • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
  • Y10T428/00—Stock material or miscellaneous articles
  • Y10T428/31504—Composite [nonstructural laminate]
  • Y10T428/31855—Of addition polymer from unsaturated monomers
  • Y10T428/31909—Next to second addition polymer from unsaturated monomers
  • Y10T428/31928—Ester, halide or nitrile of addition polymer

Definitions

• the present invention relates to a method for producing a vinyl chloride resin product having a step of bonding members made of vinyl chloride resin. Background technology
• the bonding portion is formed into a shape in which both of the objects to be bonded are in close contact with each other. If the two do not closely contact each other, an auxiliary member is interposed between them so that they adhere. Then, an organic solvent is impregnated into the contact portion, and the bonding surface is dissolved by the organic solvent and bonded.
• an organic solvent The ones that can dissolve the chloride resin are used. For example, tetrahydrofuran (THF), cyclohexanone, ethyl acetate, acetyl Tonnes, methyl ketones (MEK), etc. are used.
• organic solvent As a problem when an organic solvent is used, the organic solvent remains inside the vinyl chloride resin member.
• Organic solvents have the property of volatilizing easily, but on the other hand, they are highly compatible with vinyl chloride resin, and excess organic solvent used for bonding vinyl chloride resin evaporates. However, it is compatible with the vinyl chloride resin, and the amount of the residue remaining after infiltration is not small. The organic solvent remaining in the vinyl chloride resin is easily eluted into the aqueous solution when the product thus produced comes into contact with the aqueous solution.
• butyl chloride resin products come into direct contact with body fluids or drug solutions such as blood transfusion or infusion sets, extracorporeal circulation circuits such as human dialysis, cardiopulmonary bypass, and catheters.
• body fluids or drug solutions such as blood transfusion or infusion sets, extracorporeal circulation circuits such as human dialysis, cardiopulmonary bypass, and catheters.
• the remaining organic solvent dissolves into body fluids, especially blood or infusion solutions, and enters the patient's body.
• the chloride resin product is a blood bag or a transfusion bag, the blood preservation solution and the infusion solution in the bag are not used until they are manufactured and used. Long-term contact with the inside of the product. For this reason, when the organic solvent used as the adhesive remains, it is highly possible that the organic solvent is dissolved in the chemical solution.
• an organic solvent is present in the collected blood or the drug solution, and when the blood or the drug is administered, the organic solvent is present in the patient's body. Solvent will enter. Patients who need blood transfusions or transfusions usually have reduced physical strength, and it is extremely dangerous for such organic solvents to enter the patient's body. And.
• the purpose of the present invention is to provide a method of bonding vinyl chloride resin products, a problem of a bonding method by high frequency fusion, and a bonding method by an organic solvent.
• An object of the present invention is to provide a method for producing a vinyl chloride resin product which has solved the above problems. Disclosure of the invention
• the present invention relates to a method for producing a vinyl chloride resin product having a step of bonding vinyl chloride resin members to each other, and the vinyl chloride resin having compatibility with the vinyl chloride resin. After applying the compounding agent for resin to at least one of the adhesive parts of the salted vinyl resin member, and then bringing the adhesive parts of both members into close contact with each other. This is a manufacturing method for chlorinated butyl resin products.
• the present invention relates to a method for producing a vinyl chloride resin product having a step of bonding vinyl chloride resin members to each other, wherein the bonding step comprises: A step of applying a vinyl chloride resin combination agent exhibiting solubility to the vinyl chloride resin to at least one of the adhesive portions of the vinyl chloride resin member, and bonding the two members. And a step of crimping the part.
• the vinyl chloride resin products to be subjected to the production method of the present invention include all products having an adhesive portion between vinyl chloride resin members.
• the present invention since the present invention does not use an organic solvent as the bonding method, it is preferably used as a method for producing a medical device made of vinyl chloride resin.
• Such medical devices include bags such as blood bags, infusion bags, nutrient bags, transfusion sets, infusion sets, and winged statics.
• Set or tubes such as a needle set (Winged Infusion Set), an indwelling needle set for artificial dialysis, a connecting tube, an extension tube, etc., and a blood circuit for dialysis.
• Blood circuits such as blood circuits for cardiopulmonary bypass, blood circuits for cardiopulmonary bypass, etc., blood circuits such as blood circuits for plasma separation or plasma collection, catheters for high-calorie infusions, and neural networks
• catheters such as one-cell, suction catheter, nutritional catheter, and soft vein reservoir used in the cardiopulmonary bypass circuit. .
• the method includes a step of bringing the bonded portions of both members coated with the compounding agent for vinyl chloride resin into close contact. This As a close contact process, the two members are pressurized by applying pressure from the outside, and the other member is forcibly fitted and inserted into one member. This is done by:
• the vinyl chloride resin used in the present invention is a resin containing a compounding agent such as a plasticizer, a lubricant and an antioxidant in addition to polyvinyl chloride. Wear .
• the compounding agent for vinyl chloride resin used in the present invention has a solubility in vinyl chloride resin and a certain degree of solubility in vinyl chloride resin. In general, it is used for distributing it to vinyl chloride resin to improve or adjust its properties. It is usually used only for this purpose.
• the present invention has been made based on the fact that these compounds could not be used for these purposes, but could be used as adhesives. It is a thing.
• a compounding agent for vinyl chloride resin a compound which is liquid at room temperature can be suitably used. More specifically, as a compounding agent used in the present invention, a liquid plasticizer for a vinyl chloride resin, a liquid lubricant and the like are particularly suitable.
• liquid plasticizer examples include di-adipate (2-ethylhexyl), di-desodecyl adipate, and di-azepate (2— (Ethyl hexyl), dibutyl phthalate, di_phthalic acid (2—ethyl hexyl), diphenyl phthalate Di-H-heptanole, di-n-phthalanoic acid, n-decyl, diisodecyl phthalate, tris-trimellitic acid (2-ethyl alcohol) Trihexyl), triphosphate phosphate, phosphoric acid Triclesil, epoxylated soybean oil, polyester (medium molecular weight), and chlorinated paraffin (40% chlorinated).
• it is di-phthalic acid (2-ethylhexyl) or di-n-butyl phthalate.
• the liquid lubricant may be an internal lubricant or an external lubricant, and may be a liquid paraffin, a natural paraffin, a polystyrene wax, a hydrocarbon such as a chlorinated hydrocarbon.
• Fatty acids such as hydrogen, stearate, zinc stearate, metal stearate such as barium stearate, stearate amide, Fatty acid amides and stearyls such as lumitinic acid amide, methylene bis-stearyl amide, and ethylene bis-stearyl amide Esters such as butyl phosphate, cetyl palmitate, and monostearic acid monolide can be used.
• Particularly preferred are zinc stearate and fluidized glue. It is a fin.
• a vinyl chloride compound may be added to the compounding agent used in the present invention.
• the liquid vinyl chloride resin compounding agent used in the present invention has a high affinity, compatibility, and a certain degree of solubility with vinyl chloride resin. Easy to melt into. This means that the vinyl chloride near the application surface is easily dissolved in the liquid vinyl chloride resin compounding agent. The surfaces of the closely adhered vinyl chloride resin members are melted and adhered to each other by the liquid vinyl chloride resin compounding agent at the close contact portion. The liquid compounding agent is converted to vinyl chloride resin over time. It is absorbed inward.
• Two or more members are molded using chlorinated bubble resin.
• the shape of the member may be any shape, such as a sheet or a tube.
• the above-mentioned compound for vinyl chloride resin is applied to one or both of the bonding surfaces of the molded member, and then adheres to each other.
• the vinyl chloride product is a medical device, it will be about 12 G ° C due to the autoclave sterilization performed after the application and adhesion of the mounting platform.
• the adhesive strength is further improved by being heated by heat. Due to autoclaving, heating during autoclaving, for example, by heating to about 120 ° C, salt The bonding strength of the resin is increased due to the adhesive strength of the resin.
• the measurement of the adhesive strength was performed using an autograph manufactured by Shimadzu Corporation, and the stretching speed was measured at 100 M / min.
• the unit of the measurement result was, and the average value and the standard deviation were shown.
• Vinyl chloride resin (combination ratio, 100 parts of polyvinyl chloride, 5 parts of DOP, 5 parts of epoxy soybean oil, 5 parts of Cu—Zn stabilizer)
• To the hub of the blood collection needle connect vinyl chloride resin tube (combination ratio, polychlorinated vinyl 1Q0 part, D0P60 part, epoxy resin part).
• Soybean oil (5 parts) and Cu-Zn stabilizer (5 parts) were fitted after applying the various adhesives shown in Table 1.
• the adhesive was applied to the outer surface of the end of the vinyl chloride resin tube, and the coating length was 2 to 4.
• the mating length is about 3i.
• the bonding strength of both was measured within 30 minutes after mating and bonding. These were placed in an autoclave at about 118 ° C and sterilized for about 20 minutes.
• the adhesive strength before and after sterilization was as shown in Table 1.
• Chloride resin tube (Blending ratio, 100 parts of polychlorinated vinyl, 60 parts of D0P, 5 parts of epoxidized soybean oil, Cu-'ZII stabilizer 5 parts) and vinyl chloride resin tube (mixing ratio, 100 parts of polychlorinated vinyl, 60 parts of D DP, 5 parts of epoxy soybean oil, 5 parts of Cu-Zn Stabilizers (5 parts) were fitted with the various adhesives shown in Table 2 after applying them to the adhesive surface.
• the adhesive is the thinner vinyl chloride resin tube on the side to be inserted (outer diameter about 4. ⁇ ⁇ )
• a 2 to 4 ni cloth was placed on the outer surface of the end of the tube.
• the mating length is 4-6 ⁇ .
• the bonding strength between the two was measured within 30 minutes after mating and bonding. These were placed in an autoclave at about 118 ° C and sterilized for about 20 minutes.
• the adhesive strength before and after sterilization was as shown in Table 2.
• Vinyl chloride resin Y-tube (mixing ratio, 100 parts of polyvinyl chloride, 4 parts of DOP, 5 parts of epoxy soybean oil, 5 parts of CuZn-based stabilizer)
• Resin tube (Blending ratio, 100 parts of polychlorinated valve, 60 parts of D0P, 5 parts of epoxy soybean oil, 5 parts of Cu-Zn-based stabilizer)
• Glue is A vinyl chloride resin tube to be inserted (2 to 4 ⁇ cloth was applied to the outer surface of the end of an outer diameter of about 4.
• k UL liO In Comparative Example 6, the adhesive was not applied. These were placed in an autoclave at about 118 ° C and sterilized for about 20 minutes. The adhesive strength before sterilization and after sterilization was 3rd. It was as shown in the table.
• the present invention relates to a method for producing a vinyl chloride resin product having a step of bonding members made of the vinyl chloride resin, wherein the vinyl chloride resin product has a solubility in the vinyl chloride resin. After applying the compounding agent to at least one of the adhesive parts of the vinyl chloride resin member, a step of bringing the adhesive parts of both members into close contact with each other is provided. Particularly, in the present invention, when an organic solvent is used by using a vinyl chloride resin compounding agent showing compatibility with the vinyl chloride resin as an adhesive.

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• Chemical & Material Sciences (AREA)
• Engineering & Computer Science (AREA)
• Manufacturing & Machinery (AREA)
• Materials Engineering (AREA)
• Health & Medical Sciences (AREA)
• Chemical Kinetics & Catalysis (AREA)
• Medicinal Chemistry (AREA)
• Polymers & Plastics (AREA)
• Organic Chemistry (AREA)
• Materials For Medical Uses (AREA)
• Manufacture Of Macromolecular Shaped Articles (AREA)
• Adhesives Or Adhesive Processes (AREA)
• Lining Or Joining Of Plastics Or The Like (AREA)

Priority Applications (1)

Applications Claiming Priority (2)

Publications (1)

Family

ID=17778163

Family Applications (1)

Country Status (5)

Families Citing this family (6)

Family Cites Families (12)

• 1987
  • 1987-11-20 JP JP62292148A patent/JPH01135839A/ja active Granted
• 1988
  • 1988-11-18 AU AU27800/89A patent/AU2780089A/en active Granted
  • 1988-11-18 US US07/488,082 patent/US5135600A/en not_active Expired - Lifetime
  • 1988-11-18 WO PCT/JP1988/001170 patent/WO1989004851A1/ja not_active Ceased
  • 1988-11-18 EP EP88910103A patent/EP0485595A1/en not_active Ceased

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