WO1988006619A1 - Preparation for prophylaxis and treatment of gastro-intestinal disturbances in farm animals - Google Patents
Preparation for prophylaxis and treatment of gastro-intestinal disturbances in farm animals Download PDFInfo
- Publication number
- WO1988006619A1 WO1988006619A1 PCT/SU1987/000024 SU8700024W WO8806619A1 WO 1988006619 A1 WO1988006619 A1 WO 1988006619A1 SU 8700024 W SU8700024 W SU 8700024W WO 8806619 A1 WO8806619 A1 WO 8806619A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- biomass
- treatment
- tsmpm
- tsμpμ
- shτamma
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title claims abstract description 13
- 208000018522 Gastrointestinal disease Diseases 0.000 title claims abstract description 8
- 241001465754 Metazoa Species 0.000 title claims abstract description 6
- 238000002360 preparation method Methods 0.000 title abstract description 12
- 238000011321 prophylaxis Methods 0.000 title abstract 2
- 239000002028 Biomass Substances 0.000 claims abstract description 22
- 239000000945 filler Substances 0.000 claims abstract description 5
- 239000000203 mixture Substances 0.000 claims description 14
- 239000003814 drug Substances 0.000 claims description 13
- 229940079593 drug Drugs 0.000 claims description 13
- 241000894006 Bacteria Species 0.000 claims description 2
- 230000000813 microbial effect Effects 0.000 claims description 2
- 244000005700 microbiome Species 0.000 abstract description 7
- 238000011160 research Methods 0.000 abstract description 5
- 230000003042 antagnostic effect Effects 0.000 abstract description 3
- 238000009395 breeding Methods 0.000 abstract description 2
- 230000001488 breeding effect Effects 0.000 abstract description 2
- 241000194108 Bacillus licheniformis Species 0.000 abstract 2
- 244000063299 Bacillus subtilis Species 0.000 abstract 2
- 235000014469 Bacillus subtilis Nutrition 0.000 abstract 2
- 230000000050 nutritive effect Effects 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 25
- 238000000034 method Methods 0.000 description 9
- 230000008569 process Effects 0.000 description 8
- 230000000694 effects Effects 0.000 description 7
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 6
- 239000008103 glucose Substances 0.000 description 6
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 235000013372 meat Nutrition 0.000 description 5
- 244000144977 poultry Species 0.000 description 5
- 244000309466 calf Species 0.000 description 4
- 230000006378 damage Effects 0.000 description 4
- 229920001817 Agar Polymers 0.000 description 3
- 108010010803 Gelatin Proteins 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 239000008272 agar Substances 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 239000008273 gelatin Substances 0.000 description 3
- 229920000159 gelatin Polymers 0.000 description 3
- 235000019322 gelatine Nutrition 0.000 description 3
- 235000011852 gelatine desserts Nutrition 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 description 2
- 229910002651 NO3 Inorganic materials 0.000 description 2
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 244000144972 livestock Species 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- 239000004606 Fillers/Extenders Substances 0.000 description 1
- 108010003272 Hyaluronate lyase Proteins 0.000 description 1
- 102000001974 Hyaluronidases Human genes 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 102000015439 Phospholipases Human genes 0.000 description 1
- 108010064785 Phospholipases Proteins 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 241000382509 Vania Species 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 208000010643 digestive system disease Diseases 0.000 description 1
- 230000009429 distress Effects 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 208000018685 gastrointestinal system disease Diseases 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 229960002773 hyaluronidase Drugs 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 description 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 208000032839 leukemia Diseases 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 229910000679 solder Inorganic materials 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- WTHDKMILWLGDKL-UHFFFAOYSA-N urea;hydrate Chemical compound O.NC(N)=O WTHDKMILWLGDKL-UHFFFAOYSA-N 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/07—Bacillus
Definitions
- ⁇ e ⁇ ⁇ e ⁇ i ⁇ d of ⁇ uzhayuschey s ⁇ edy (from v ⁇ zdu ⁇ a, ⁇ edme ⁇ v u ⁇ da, ⁇ b ⁇ lny ⁇ zhiv ⁇ ny ⁇ , ⁇ ⁇ e ⁇ s ⁇ nala and d ⁇ ugi ⁇ is ⁇ chni ⁇ v) in ⁇ ganizm zhiv ⁇ ny ⁇ m ⁇ gu ⁇ ⁇ ada ⁇ ⁇ azlichnye ⁇ a ⁇ gennye and usl ⁇ vn ⁇ ⁇ a ⁇ gennye mi ⁇ ganizmy (en ⁇ e ⁇ a ⁇ gennye ⁇ ishechnye ⁇ al ⁇ ch ⁇ i, s ⁇ a- ⁇ il ⁇ i, ⁇ ei, ⁇ lebsielly 'and salm ⁇ nell
- the drugs are more effective for the treatment and treatment of gastrointestinal diseases of the living from vascular microculture.
- Eti ⁇ réelle -2- Injuries are at risk of physical injury to the stomach and the stomach, which is associated with gastrointestinal disease, ⁇ réelle ⁇ , for example ⁇ ,
- the indications indicated include one type of microorganism that does not provide a wide range of its antagonistic features.
- the basic task of the invention was to alter the biomass of bacteria and use new strains of microbial diseases to treat medications for the treatment of patients
- the quick link is desirable with a dry link.
- the culture produces glucose, arabinosis, beckoning, and the formation of an acid without gas.
- the operation of Facebook - Positive is positive.
- the culture does not produce gas from ⁇ 0 3 under anaerobic conditions; it does not produce arginine dihydrogenase.
- the crop grows in a environment that contains 7% of ya
- a meat and poultry bouillon is used to produce a small-film, sometimes with an extra-thick film.
- the culture is exploring catalase.
- the product is available on the market.
- the inventive product provides a pure, crystallized dry mass of light and non-volatile light that is not consumable to us.
- the bulk for water is not more than 5%.
- the product is emitted in glass ampoules with a content of 250 mg of dry substance (300-400 milliliters of microcells) or in glass flasks with a content of 500 mg (600 mg).
- the claimed ⁇ e ⁇ a ⁇ a ⁇ m ⁇ zhe ⁇ by ⁇ is ⁇ lz ⁇ van in ⁇ aches ⁇ ve s ⁇ eds ⁇ va ⁇ ila ⁇ i ⁇ i or ⁇ aches ⁇ ve s ⁇ eds ⁇ va treatment ⁇ s ⁇ y ⁇ zhelud ⁇ chn ⁇ - ⁇ ishechny ⁇ zab ⁇ levany m ⁇ l ⁇ dnya ⁇ a sels ⁇ - ⁇ zyays ⁇ venny ⁇ zhiv ⁇ ny ⁇ (disba ⁇ e ⁇ i ⁇ za, ⁇ liba ⁇ e ⁇ i ⁇ za, salm ⁇ nelleza, ⁇ azlichny ⁇ d ⁇ ugi ⁇ ⁇ s ⁇ y ⁇ zhelud ⁇ chn ⁇ - ⁇ ishechny ⁇ zab ⁇ levany sels ⁇ zyays venny ⁇ zhiv ⁇ ny ⁇ , vyzvanny ⁇ ⁇ a- ⁇ gennymi and usl ⁇ vn ⁇ pathogenic microorganisms).
- test results of the claimed product showed that out of 328 newborn calves, which were purchased by the claimed device, 19 of them had any injuries. ⁇ live group of 185 live
- the claimed medication was changed to 284 calves with various gastrointestinal diseases
- the inventive process was designated as the next one.
- Compound ampoules 300-400 milligrams of micro-cells were mixed in one milk or water, they were cooled and cooled to 25–30 ° C, and they were allowed to cool.
- the claimed preparation showed a high therapeutic and preventive effect.
- the product is characterized by a high rate of antagonism to the static response to various types of microorganisms - pathogens.
- the product helps to increase the protective reactions of the organism of animals (induction of the endogenous interactions,
- the claimed process is as follows.
- ⁇ Brass As a filling medium, use a mixture of a quick-release mixture of quick-release or gelatin with sugar or glucose. The resulting mixture is poured into a stylish ampoule 1 and placed in a corner, a cracker for 24 hours at a temperature not exceeding -20 ° C. The product is licensed for at least 44 hours and operating at -20 ° to + 20 ° ⁇ . After filizirovaniya ampoules solder. The inventive preparation keeps the activity and the duration of the storage for at least 2 years.
- the test for harmlessness leads to the following test: when administered directly, at least 5 mice weighing 18-22 grams are much more lively than the mouse, but the weight is very good. on the fifth day of observation.
- the conversion of speci fi c activity is carried out by the following process. Researches the antagonistic properties of -10- sections of microcultures included in the composition of the drug, in addition to testing, the number of tests carried out by the Party is limited,
- test results are presented in the table. For example, 2.
- the inventive product is of the following composition, in% (%): biomass strain . ⁇ . ⁇ admir ⁇ transaction ⁇ ⁇ ⁇ £ ⁇ -2336 20 35 5th gelatin solution. 21 sugar 4 -II-
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE873790919T DE3790919T1 (de) | 1987-02-24 | 1987-02-24 | Arzneimittel zur prophylaxe und behandlung von gastrointerfinalen erkrankungen des landwirtschaftsviehs |
| PCT/SU1987/000024 WO1988006619A1 (en) | 1987-02-24 | 1987-02-24 | Preparation for prophylaxis and treatment of gastro-intestinal disturbances in farm animals |
| JP62502918A JPH01502340A (ja) | 1987-02-24 | 1987-02-24 | 家畜の胃腸病の予防及び処置のための製剤 |
| CH4117/88A CH674149A5 (enrdf_load_stackoverflow) | 1987-02-24 | 1988-02-24 | |
| GB8823554A GB2209343B (en) | 1987-02-24 | 1988-10-07 | Preparation for prophylaxis and treatment of gastro-intestinal disturbances in farm animals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/SU1987/000024 WO1988006619A1 (en) | 1987-02-24 | 1987-02-24 | Preparation for prophylaxis and treatment of gastro-intestinal disturbances in farm animals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO1988006619A1 true WO1988006619A1 (en) | 1988-09-07 |
Family
ID=21617080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/SU1987/000024 WO1988006619A1 (en) | 1987-02-24 | 1987-02-24 | Preparation for prophylaxis and treatment of gastro-intestinal disturbances in farm animals |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPH01502340A (enrdf_load_stackoverflow) |
| CH (1) | CH674149A5 (enrdf_load_stackoverflow) |
| DE (1) | DE3790919T1 (enrdf_load_stackoverflow) |
| GB (1) | GB2209343B (enrdf_load_stackoverflow) |
| WO (1) | WO1988006619A1 (enrdf_load_stackoverflow) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364788A (en) * | 1991-07-01 | 1994-11-15 | Ahc Inc. | Pure culture of Bacillus subtilis FERM BP-3418 |
| EP1093803A3 (fr) * | 1996-10-23 | 2004-03-31 | Sanofi-Synthelabo | Composition cosmétique contenant un antagoniste des récepteurs du neuropeptide Y |
| US9005601B2 (en) | 2010-07-16 | 2015-04-14 | The Board Of Trustees Of The University Of Arkansas | Methods and compositions including spore-forming bacteria for increasing the health of animals |
| US9107938B2 (en) | 2010-09-30 | 2015-08-18 | The Board Of Trustees Of The University Of Arkansas | Methods of selecting and using therapeutic and prophylactic probiotic cultures to reduce bacterial pathogen loads |
| US9393275B2 (en) | 2012-08-01 | 2016-07-19 | Novozymes A/S | Probiotic for amelioration of coccidiosis vaccine reaction |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7276194A (en) * | 1993-08-11 | 1995-02-28 | Ahc Inc. | Immunopotentiator and method of immunopotentiating animal with the same |
| FR2758051B1 (fr) * | 1997-01-06 | 1999-12-17 | Cobiotex | Procedes d'eradication systematique du portage d'agents pathogenes par des animaux et compositions mises en oeuvre dans ces procedes |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1554525A (en) * | 1976-12-07 | 1979-10-24 | Grace W R & Co | Ruminant feed additive |
| GB2138023A (en) * | 1983-03-29 | 1984-10-17 | Mitsui Toatsu Chemicals | Bacillus licheniformis used in animal feeds |
| EP0145798A1 (de) * | 1983-12-09 | 1985-06-26 | Miles Kali-Chemie GmbH & Co. KG Biochemisches Werk | Bacillus subtilis DSM 2704 und Verfahren zur Herstellung von Alpha-Amylase |
-
1987
- 1987-02-24 JP JP62502918A patent/JPH01502340A/ja active Pending
- 1987-02-24 WO PCT/SU1987/000024 patent/WO1988006619A1/ru active Application Filing
- 1987-02-24 DE DE873790919T patent/DE3790919T1/de not_active Withdrawn
-
1988
- 1988-02-24 CH CH4117/88A patent/CH674149A5/de not_active IP Right Cessation
- 1988-10-07 GB GB8823554A patent/GB2209343B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1554525A (en) * | 1976-12-07 | 1979-10-24 | Grace W R & Co | Ruminant feed additive |
| GB2138023A (en) * | 1983-03-29 | 1984-10-17 | Mitsui Toatsu Chemicals | Bacillus licheniformis used in animal feeds |
| EP0145798A1 (de) * | 1983-12-09 | 1985-06-26 | Miles Kali-Chemie GmbH & Co. KG Biochemisches Werk | Bacillus subtilis DSM 2704 und Verfahren zur Herstellung von Alpha-Amylase |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364788A (en) * | 1991-07-01 | 1994-11-15 | Ahc Inc. | Pure culture of Bacillus subtilis FERM BP-3418 |
| EP1093803A3 (fr) * | 1996-10-23 | 2004-03-31 | Sanofi-Synthelabo | Composition cosmétique contenant un antagoniste des récepteurs du neuropeptide Y |
| US9005601B2 (en) | 2010-07-16 | 2015-04-14 | The Board Of Trustees Of The University Of Arkansas | Methods and compositions including spore-forming bacteria for increasing the health of animals |
| US9107938B2 (en) | 2010-09-30 | 2015-08-18 | The Board Of Trustees Of The University Of Arkansas | Methods of selecting and using therapeutic and prophylactic probiotic cultures to reduce bacterial pathogen loads |
| US9393275B2 (en) | 2012-08-01 | 2016-07-19 | Novozymes A/S | Probiotic for amelioration of coccidiosis vaccine reaction |
Also Published As
| Publication number | Publication date |
|---|---|
| CH674149A5 (enrdf_load_stackoverflow) | 1990-05-15 |
| GB2209343A (en) | 1989-05-10 |
| DE3790919T1 (de) | 1989-03-23 |
| GB8823554D0 (en) | 1989-01-25 |
| JPH01502340A (ja) | 1989-08-17 |
| GB2209343B (en) | 1990-09-12 |
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