WO1988006619A1 - Preparation for prophylaxis and treatment of gastro-intestinal disturbances in farm animals - Google Patents
Preparation for prophylaxis and treatment of gastro-intestinal disturbances in farm animals Download PDFInfo
- Publication number
- WO1988006619A1 WO1988006619A1 PCT/SU1987/000024 SU8700024W WO8806619A1 WO 1988006619 A1 WO1988006619 A1 WO 1988006619A1 SU 8700024 W SU8700024 W SU 8700024W WO 8806619 A1 WO8806619 A1 WO 8806619A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- biomass
- treatment
- tsmpm
- tsμpμ
- shτamma
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/07—Bacillus
Definitions
- ⁇ e ⁇ ⁇ e ⁇ i ⁇ d of ⁇ uzhayuschey s ⁇ edy (from v ⁇ zdu ⁇ a, ⁇ edme ⁇ v u ⁇ da, ⁇ b ⁇ lny ⁇ zhiv ⁇ ny ⁇ , ⁇ ⁇ e ⁇ s ⁇ nala and d ⁇ ugi ⁇ is ⁇ chni ⁇ v) in ⁇ ganizm zhiv ⁇ ny ⁇ m ⁇ gu ⁇ ⁇ ada ⁇ ⁇ azlichnye ⁇ a ⁇ gennye and usl ⁇ vn ⁇ ⁇ a ⁇ gennye mi ⁇ ganizmy (en ⁇ e ⁇ a ⁇ gennye ⁇ ishechnye ⁇ al ⁇ ch ⁇ i, s ⁇ a- ⁇ il ⁇ i, ⁇ ei, ⁇ lebsielly 'and salm ⁇ nell
- the drugs are more effective for the treatment and treatment of gastrointestinal diseases of the living from vascular microculture.
- Eti ⁇ réelle -2- Injuries are at risk of physical injury to the stomach and the stomach, which is associated with gastrointestinal disease, ⁇ réelle ⁇ , for example ⁇ ,
- the indications indicated include one type of microorganism that does not provide a wide range of its antagonistic features.
- the basic task of the invention was to alter the biomass of bacteria and use new strains of microbial diseases to treat medications for the treatment of patients
- the quick link is desirable with a dry link.
- the culture produces glucose, arabinosis, beckoning, and the formation of an acid without gas.
- the operation of Facebook - Positive is positive.
- the culture does not produce gas from ⁇ 0 3 under anaerobic conditions; it does not produce arginine dihydrogenase.
- the crop grows in a environment that contains 7% of ya
- a meat and poultry bouillon is used to produce a small-film, sometimes with an extra-thick film.
- the culture is exploring catalase.
- the product is available on the market.
- the inventive product provides a pure, crystallized dry mass of light and non-volatile light that is not consumable to us.
- the bulk for water is not more than 5%.
- the product is emitted in glass ampoules with a content of 250 mg of dry substance (300-400 milliliters of microcells) or in glass flasks with a content of 500 mg (600 mg).
- the claimed ⁇ e ⁇ a ⁇ a ⁇ m ⁇ zhe ⁇ by ⁇ is ⁇ lz ⁇ van in ⁇ aches ⁇ ve s ⁇ eds ⁇ va ⁇ ila ⁇ i ⁇ i or ⁇ aches ⁇ ve s ⁇ eds ⁇ va treatment ⁇ s ⁇ y ⁇ zhelud ⁇ chn ⁇ - ⁇ ishechny ⁇ zab ⁇ levany m ⁇ l ⁇ dnya ⁇ a sels ⁇ - ⁇ zyays ⁇ venny ⁇ zhiv ⁇ ny ⁇ (disba ⁇ e ⁇ i ⁇ za, ⁇ liba ⁇ e ⁇ i ⁇ za, salm ⁇ nelleza, ⁇ azlichny ⁇ d ⁇ ugi ⁇ ⁇ s ⁇ y ⁇ zhelud ⁇ chn ⁇ - ⁇ ishechny ⁇ zab ⁇ levany sels ⁇ zyays venny ⁇ zhiv ⁇ ny ⁇ , vyzvanny ⁇ ⁇ a- ⁇ gennymi and usl ⁇ vn ⁇ pathogenic microorganisms).
- test results of the claimed product showed that out of 328 newborn calves, which were purchased by the claimed device, 19 of them had any injuries. ⁇ live group of 185 live
- the claimed medication was changed to 284 calves with various gastrointestinal diseases
- the inventive process was designated as the next one.
- Compound ampoules 300-400 milligrams of micro-cells were mixed in one milk or water, they were cooled and cooled to 25–30 ° C, and they were allowed to cool.
- the claimed preparation showed a high therapeutic and preventive effect.
- the product is characterized by a high rate of antagonism to the static response to various types of microorganisms - pathogens.
- the product helps to increase the protective reactions of the organism of animals (induction of the endogenous interactions,
- the claimed process is as follows.
- ⁇ Brass As a filling medium, use a mixture of a quick-release mixture of quick-release or gelatin with sugar or glucose. The resulting mixture is poured into a stylish ampoule 1 and placed in a corner, a cracker for 24 hours at a temperature not exceeding -20 ° C. The product is licensed for at least 44 hours and operating at -20 ° to + 20 ° ⁇ . After filizirovaniya ampoules solder. The inventive preparation keeps the activity and the duration of the storage for at least 2 years.
- the test for harmlessness leads to the following test: when administered directly, at least 5 mice weighing 18-22 grams are much more lively than the mouse, but the weight is very good. on the fifth day of observation.
- the conversion of speci fi c activity is carried out by the following process. Researches the antagonistic properties of -10- sections of microcultures included in the composition of the drug, in addition to testing, the number of tests carried out by the Party is limited,
- test results are presented in the table. For example, 2.
- the inventive product is of the following composition, in% (%): biomass strain . ⁇ . ⁇ admir ⁇ transaction ⁇ ⁇ ⁇ £ ⁇ -2336 20 35 5th gelatin solution. 21 sugar 4 -II-
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/SU1987/000024 WO1988006619A1 (en) | 1987-02-24 | 1987-02-24 | Preparation for prophylaxis and treatment of gastro-intestinal disturbances in farm animals |
DE873790919T DE3790919T1 (de) | 1987-02-24 | 1987-02-24 | Arzneimittel zur prophylaxe und behandlung von gastrointerfinalen erkrankungen des landwirtschaftsviehs |
JP62502918A JPH01502340A (ja) | 1987-02-24 | 1987-02-24 | 家畜の胃腸病の予防及び処置のための製剤 |
CH4117/88A CH674149A5 (de) | 1987-02-24 | 1988-02-24 | |
GB8823554A GB2209343B (en) | 1987-02-24 | 1988-10-07 | Preparation for prophylaxis and treatment of gastro-intestinal disturbances in farm animals |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/SU1987/000024 WO1988006619A1 (en) | 1987-02-24 | 1987-02-24 | Preparation for prophylaxis and treatment of gastro-intestinal disturbances in farm animals |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1988006619A1 true WO1988006619A1 (en) | 1988-09-07 |
Family
ID=21617080
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/SU1987/000024 WO1988006619A1 (en) | 1987-02-24 | 1987-02-24 | Preparation for prophylaxis and treatment of gastro-intestinal disturbances in farm animals |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPH01502340A (de) |
CH (1) | CH674149A5 (de) |
DE (1) | DE3790919T1 (de) |
GB (1) | GB2209343B (de) |
WO (1) | WO1988006619A1 (de) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5364788A (en) * | 1991-07-01 | 1994-11-15 | Ahc Inc. | Pure culture of Bacillus subtilis FERM BP-3418 |
EP1093803A2 (de) * | 1996-10-23 | 2001-04-25 | Sanofi-Synthelabo | Kosmetische Zubereitung Antagonisten des Neuropeptid-Y-Rezeptors enthaltend |
US9005601B2 (en) | 2010-07-16 | 2015-04-14 | The Board Of Trustees Of The University Of Arkansas | Methods and compositions including spore-forming bacteria for increasing the health of animals |
US9107938B2 (en) | 2010-09-30 | 2015-08-18 | The Board Of Trustees Of The University Of Arkansas | Methods of selecting and using therapeutic and prophylactic probiotic cultures to reduce bacterial pathogen loads |
US9393275B2 (en) | 2012-08-01 | 2016-07-19 | Novozymes A/S | Probiotic for amelioration of coccidiosis vaccine reaction |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995004539A1 (fr) * | 1993-08-11 | 1995-02-16 | Ahc Inc. | Adjuvant d'immunite et procede permettant de renforcer l'immunite d'un animal avec cet adjuvant |
FR2758051B1 (fr) * | 1997-01-06 | 1999-12-17 | Cobiotex | Procedes d'eradication systematique du portage d'agents pathogenes par des animaux et compositions mises en oeuvre dans ces procedes |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1554525A (en) * | 1976-12-07 | 1979-10-24 | Grace W R & Co | Ruminant feed additive |
GB2138023A (en) * | 1983-03-29 | 1984-10-17 | Mitsui Toatsu Chemicals | Bacillus licheniformis used in animal feeds |
EP0145798A1 (de) * | 1983-12-09 | 1985-06-26 | Miles Kali-Chemie GmbH & Co. KG Biochemisches Werk | Bacillus subtilis DSM 2704 und Verfahren zur Herstellung von Alpha-Amylase |
-
1987
- 1987-02-24 JP JP62502918A patent/JPH01502340A/ja active Pending
- 1987-02-24 WO PCT/SU1987/000024 patent/WO1988006619A1/ru active Application Filing
- 1987-02-24 DE DE873790919T patent/DE3790919T1/de not_active Withdrawn
-
1988
- 1988-02-24 CH CH4117/88A patent/CH674149A5/de not_active IP Right Cessation
- 1988-10-07 GB GB8823554A patent/GB2209343B/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1554525A (en) * | 1976-12-07 | 1979-10-24 | Grace W R & Co | Ruminant feed additive |
GB2138023A (en) * | 1983-03-29 | 1984-10-17 | Mitsui Toatsu Chemicals | Bacillus licheniformis used in animal feeds |
EP0145798A1 (de) * | 1983-12-09 | 1985-06-26 | Miles Kali-Chemie GmbH & Co. KG Biochemisches Werk | Bacillus subtilis DSM 2704 und Verfahren zur Herstellung von Alpha-Amylase |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5364788A (en) * | 1991-07-01 | 1994-11-15 | Ahc Inc. | Pure culture of Bacillus subtilis FERM BP-3418 |
EP1093803A2 (de) * | 1996-10-23 | 2001-04-25 | Sanofi-Synthelabo | Kosmetische Zubereitung Antagonisten des Neuropeptid-Y-Rezeptors enthaltend |
EP1093803A3 (de) * | 1996-10-23 | 2004-03-31 | Sanofi-Synthelabo | Eine Kosmetische Zubereitung die Antagonisten des Neuropeptid-Y-Rezeptors enthaltet |
US9005601B2 (en) | 2010-07-16 | 2015-04-14 | The Board Of Trustees Of The University Of Arkansas | Methods and compositions including spore-forming bacteria for increasing the health of animals |
US9107938B2 (en) | 2010-09-30 | 2015-08-18 | The Board Of Trustees Of The University Of Arkansas | Methods of selecting and using therapeutic and prophylactic probiotic cultures to reduce bacterial pathogen loads |
US9393275B2 (en) | 2012-08-01 | 2016-07-19 | Novozymes A/S | Probiotic for amelioration of coccidiosis vaccine reaction |
Also Published As
Publication number | Publication date |
---|---|
CH674149A5 (de) | 1990-05-15 |
GB2209343A (en) | 1989-05-10 |
JPH01502340A (ja) | 1989-08-17 |
GB2209343B (en) | 1990-09-12 |
GB8823554D0 (en) | 1989-01-25 |
DE3790919T1 (de) | 1989-03-23 |
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