UY39221A - Anticuerpos contra el sars-cov-2 y métodos de selección y uso de los mismos - Google Patents

Anticuerpos contra el sars-cov-2 y métodos de selección y uso de los mismos

Info

Publication number
UY39221A
UY39221A UY0001039221A UY39221A UY39221A UY 39221 A UY39221 A UY 39221A UY 0001039221 A UY0001039221 A UY 0001039221A UY 39221 A UY39221 A UY 39221A UY 39221 A UY39221 A UY 39221A
Authority
UY
Uruguay
Prior art keywords
cov
methods
same
sars
selection
Prior art date
Application number
UY0001039221A
Other languages
English (en)
Inventor
Mark Esser
James Steinhardt
MCTAMNEY II Patrick
LOO Yueh-Ming
M Varkey Reena
Qun Du
Saravanan RAJAN
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of UY39221A publication Critical patent/UY39221A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1002—Coronaviridae
    • C07K16/1003—Severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2 or Covid-19]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/165—Coronaviridae, e.g. avian infectious bronchitis virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente divulgación proporciona anticuerpos y fragmentos de unión a antígeno de los mismos que se unen específicamente a la proteína espicular del SARS-CoV-2 y métodos para elaborar y seleccionar los mismos. Los anticuerpos pueden usarse, por ejemplo, en la profilaxis, profilaxis posterior a la exposición o tratamiento de la infección por SARS-CoV-2. Los anticuerpos también se pueden usar para detectar la infección por SARS-CoV-2 en un sujeto.
UY0001039221A 2020-05-17 2021-05-18 Anticuerpos contra el sars-cov-2 y métodos de selección y uso de los mismos UY39221A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202063026121P 2020-05-17 2020-05-17

Publications (1)

Publication Number Publication Date
UY39221A true UY39221A (es) 2021-12-31

Family

ID=76098926

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001039221A UY39221A (es) 2020-05-17 2021-05-18 Anticuerpos contra el sars-cov-2 y métodos de selección y uso de los mismos

Country Status (19)

Country Link
US (2) US20210355196A1 (es)
EP (1) EP4153312A1 (es)
JP (1) JP2023528235A (es)
KR (1) KR20230010749A (es)
CN (1) CN115697491A (es)
AR (1) AR122111A1 (es)
AU (1) AU2021275361A1 (es)
BR (1) BR112022023088A2 (es)
CA (1) CA3182150A1 (es)
CL (1) CL2022003177A1 (es)
CO (1) CO2022017690A2 (es)
CR (1) CR20220646A (es)
EC (1) ECSP22094536A (es)
IL (1) IL297977A (es)
MX (1) MX2022014422A (es)
PE (1) PE20231376A1 (es)
TW (1) TW202208423A (es)
UY (1) UY39221A (es)
WO (1) WO2021233834A1 (es)

Families Citing this family (9)

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AU2020340881A1 (en) 2020-04-02 2021-10-21 Regeneron Pharmaceuticals, Inc. Anti-SARS-CoV-2-spike glycoprotein antibodies and antigen-binding fragments
CN116057069A (zh) 2020-06-03 2023-05-02 瑞泽恩制药公司 用抗SARS-CoV-2刺突糖蛋白抗体治疗或预防SARS-CoV-2感染和COVID-19的方法
BR112023002234A2 (pt) * 2020-08-10 2023-03-07 Astrazeneca Uk Ltd Anticorpos sars-cov-2 para tratamento e prevenção de covid-19
WO2022263638A1 (en) * 2021-06-17 2022-12-22 Centre Hospitalier Universitaire Vaudois (C.H.U.V.) Anti-sars-cov-2 antibodies and use thereof in the treatment of sars-cov-2 infection
CA3225575A1 (en) * 2021-07-14 2023-01-19 Regeneron Pharmaceuticals, Inc. Anti-sars-cov-2-spike glycoprotein antibodies and antigen-binding fragments
WO2023141176A2 (en) * 2022-01-19 2023-07-27 Icahn School Of Medicine At Mount Sinai Neutralizing antibodies and antigen-binding fragments thereof against omicron and other coronavirus variants, and methods of making and using the same
TW202342510A (zh) 2022-02-18 2023-11-01 英商Ｒｑ生物科技有限公司 抗體
CN115286712B (zh) * 2022-03-18 2024-09-27 北京百普赛斯医学检验实验室有限公司 新型冠状病毒Delta突变株特异性抗体及其应用
CN116041494B (zh) * 2022-12-12 2024-08-20 首都医科大学 一种针对SARS-CoV或SARS-CoV-2的单克隆抗体、其制备方法及应用

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Also Published As

Publication number Publication date
TW202208423A (zh) 2022-03-01
AU2021275361A1 (en) 2023-01-19
CL2022003177A1 (es) 2023-07-28
IL297977A (en) 2023-01-01
EP4153312A1 (en) 2023-03-29
CN115697491A (zh) 2023-02-03
WO2021233834A1 (en) 2021-11-25
CR20220646A (es) 2023-10-23
US20210355196A1 (en) 2021-11-18
ECSP22094536A (es) 2023-01-31
CO2022017690A2 (es) 2022-12-20
AR122111A1 (es) 2022-08-17
BR112022023088A2 (pt) 2022-12-20
CA3182150A1 (en) 2021-11-25
JP2023528235A (ja) 2023-07-04
PE20231376A1 (es) 2023-09-07
US20240182548A1 (en) 2024-06-06
MX2022014422A (es) 2022-12-07
KR20230010749A (ko) 2023-01-19

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