UY39091A - Procedimiento para obtener un inhibidor de proteinasa alfa-1 - Google Patents
Procedimiento para obtener un inhibidor de proteinasa alfa-1Info
- Publication number
- UY39091A UY39091A UY0001039091A UY39091A UY39091A UY 39091 A UY39091 A UY 39091A UY 0001039091 A UY0001039091 A UY 0001039091A UY 39091 A UY39091 A UY 39091A UY 39091 A UY39091 A UY 39091A
- Authority
- UY
- Uruguay
- Prior art keywords
- a1pi
- alpha
- proteinase inhibitor
- procedure
- solution
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8125—Alpha-1-antitrypsin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Water Supply & Treatment (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Abstract
Procedimientos para obtener un inhibidor de proteinasa alfa-1 (A1PI) altamente concentrado que comprende una etapa de preparar una solución de A1PI concentrando una solución inicial de A1PI mediante filtración de flujo tangencial (TFF) contra agua, en el que la concentración final de A1PI en la solución concentrada es, como mínimo, 110 mg/ml.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062981410P | 2020-02-25 | 2020-02-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY39091A true UY39091A (es) | 2021-08-31 |
Family
ID=74758764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY0001039091A UY39091A (es) | 2020-02-25 | 2021-02-22 | Procedimiento para obtener un inhibidor de proteinasa alfa-1 |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP4110808A1 (es) |
| JP (1) | JP2023515431A (es) |
| KR (1) | KR20220145352A (es) |
| CN (1) | CN115135667A (es) |
| AR (1) | AR121391A1 (es) |
| AU (1) | AU2021225310A1 (es) |
| BR (1) | BR112022016234A2 (es) |
| CA (1) | CA3168165A1 (es) |
| IL (1) | IL295661A (es) |
| MX (1) | MX2022010087A (es) |
| TW (1) | TW202139973A (es) |
| UY (1) | UY39091A (es) |
| WO (1) | WO2021170531A1 (es) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6462180B1 (en) | 1999-11-24 | 2002-10-08 | Bayer Corporation | Method of preparing α-1 proteinase inhibitor |
| BRPI0915948A2 (pt) | 2008-07-18 | 2019-04-09 | Talecris Biotherapeutics Inc | método de preparar inibidor de alfa-1 proteinase |
| MX2012005132A (es) | 2009-11-03 | 2012-07-25 | Grifols Therapeutics Inc | Composicion, metodo y kit para inhibidor de alfa-1 proteinasa. |
| US9353165B2 (en) * | 2012-07-25 | 2016-05-31 | Grifols, S.A. | Purification of cell culture derived alpha1 protease inhibitor |
| US10550148B2 (en) * | 2014-06-16 | 2020-02-04 | Emd Millipore Corporation | Methods for increasing the capacity of flow-through processes |
| US20210032314A1 (en) * | 2018-03-12 | 2021-02-04 | Protease Pharmaceuticals Inc. | Methods and compositions for alpha-1 antitrypsin related disease disorders |
| IL267923B2 (en) * | 2018-08-02 | 2023-06-01 | Grifols Worldwide Operations Ltd | The composition containing the most concentrated alpha-1 type protein inhibitor and a method for obtaining it |
-
2021
- 2021-02-22 UY UY0001039091A patent/UY39091A/es unknown
- 2021-02-22 TW TW110106017A patent/TW202139973A/zh unknown
- 2021-02-22 JP JP2022549348A patent/JP2023515431A/ja active Pending
- 2021-02-22 AU AU2021225310A patent/AU2021225310A1/en active Pending
- 2021-02-22 CA CA3168165A patent/CA3168165A1/en active Pending
- 2021-02-22 MX MX2022010087A patent/MX2022010087A/es unknown
- 2021-02-22 CN CN202180014889.7A patent/CN115135667A/zh active Pending
- 2021-02-22 KR KR1020227031517A patent/KR20220145352A/ko active Search and Examination
- 2021-02-22 EP EP21708169.4A patent/EP4110808A1/en active Pending
- 2021-02-22 WO PCT/EP2021/054302 patent/WO2021170531A1/en unknown
- 2021-02-22 AR ARP210100447A patent/AR121391A1/es unknown
- 2021-02-22 IL IL295661A patent/IL295661A/en unknown
- 2021-02-22 BR BR112022016234A patent/BR112022016234A2/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4110808A1 (en) | 2023-01-04 |
| JP2023515431A (ja) | 2023-04-13 |
| AU2021225310A1 (en) | 2022-10-06 |
| CN115135667A (zh) | 2022-09-30 |
| TW202139973A (zh) | 2021-11-01 |
| WO2021170531A1 (en) | 2021-09-02 |
| CA3168165A1 (en) | 2021-09-02 |
| AR121391A1 (es) | 2022-06-01 |
| IL295661A (en) | 2022-10-01 |
| KR20220145352A (ko) | 2022-10-28 |
| BR112022016234A2 (pt) | 2022-10-11 |
| MX2022010087A (es) | 2022-09-02 |
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