UY33272A - Inhibidores heterocíclicos de los receptores de histamina para el tratamiento de una enfermedad - Google Patents

Inhibidores heterocíclicos de los receptores de histamina para el tratamiento de una enfermedad

Info

Publication number
UY33272A
UY33272A UY0001033272A UY33272A UY33272A UY 33272 A UY33272 A UY 33272A UY 0001033272 A UY0001033272 A UY 0001033272A UY 33272 A UY33272 A UY 33272A UY 33272 A UY33272 A UY 33272A
Authority
UY
Uruguay
Prior art keywords
treatment
disease
histamine receptors
heterocyclic inhibitors
inhibitors
Prior art date
Application number
UY0001033272A
Other languages
English (en)
Inventor
Beauregard Clay
Gamache Daniel
Yanni John
Borchardt Allen
Davis Robert
Daniel P Becker
Noble Stewart
Hellberg Mark
Peter G Klimko
Qiu Zhihai
Payne Joseph
Original Assignee
Kalypsys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kalypsys Inc filed Critical Kalypsys Inc
Publication of UY33272A publication Critical patent/UY33272A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)

Abstract

La presente invención se refiere a compuestos y métodos que pueden ser útiles como inhibidores de H1R y/o H4R para el tratamiento o la prevención de enfermedades inflamatorias, autoinmunes, alérgicas y oculares.
UY0001033272A 2010-03-10 2011-03-10 Inhibidores heterocíclicos de los receptores de histamina para el tratamiento de una enfermedad UY33272A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31261910P 2010-03-10 2010-03-10

Publications (1)

Publication Number Publication Date
UY33272A true UY33272A (es) 2011-10-31

Family

ID=44564100

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001033272A UY33272A (es) 2010-03-10 2011-03-10 Inhibidores heterocíclicos de los receptores de histamina para el tratamiento de una enfermedad

Country Status (4)

Country Link
US (1) US20110257137A1 (es)
TW (1) TW201204727A (es)
UY (1) UY33272A (es)
WO (1) WO2011112731A2 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110065698A1 (en) * 2009-08-26 2011-03-17 Cylene Pharmaceuticals, Inc. Novel protein kinase modulators
EP2616468A4 (en) * 2010-09-16 2014-02-26 Hutchison Medipharma Ltd CONDENSED HETEROARYLES AND USES THEREOF
KR101567610B1 (ko) 2010-11-04 2015-11-09 주식회사 엘지화학 신규한 질소 함유 헤테로환 화합물 및 이를 이용한 유기 전자 소자
KR101834362B1 (ko) 2011-03-18 2018-03-05 바이엘 인텔렉쳐 프로퍼티 게엠베하 N-(3-카바모일페닐)-1h-피라졸-5-카복사미드 유도체 및 동물 해충을 구제하기 위한 그의 용도
EA034193B1 (ru) 2011-04-21 2020-01-15 Оригенис Гмбх Гетероциклические соединения в качестве ингибиторов киназ
RU2628074C2 (ru) * 2011-09-30 2017-08-14 Си энд Си РИСЕРЧ ЛЭБОРЕТРИЗ ТРИЦИКЛИЧЕСКИЕ АЗОТСОДЕРЖАЩИЕ ПРОИЗВОДНЫЕ ИМИДАЗО[4,5-с]ПИРИДИНА, ОБЛАДАЮЩИЕ ИНГИБИРУЮЩЕЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ РЕЦЕПТОРА ГИСТАМИНА 4 (hH4R)
US9464085B2 (en) * 2012-08-17 2016-10-11 AbbVie Deutschland GmbH & Co. KG Inhibitor compounds of phosphodiesterase type 10A
WO2014060113A1 (en) * 2012-10-19 2014-04-24 Origenis Gmbh Novel kinase inhibitors
JP6211189B2 (ja) * 2013-07-17 2017-10-11 ヒソン・マテリアル・リミテッドＨｅｅｓｕｎｇ Ｍａｔｅｒｉａｌ Ｌｔｄ． 窒素含有多環式化合物およびそれを用いた有機発光素子
WO2016199943A1 (en) * 2015-06-11 2016-12-15 Takeda Pharmaceutical Company Limited Heterocyclic compounds
KR102070265B1 (ko) 2017-01-26 2020-01-28 한국화학연구원 신규한 [1,2,4]트리아졸로[4,3-a]퀴녹살린 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 BET 단백질 관련 질환의 예방 또는 치료용 약학적 조성물
KR20200009001A (ko) * 2017-05-17 2020-01-29 가부시끼가이샤 도꾸야마 디아미노벤젠 화합물의 제조 방법
TW202021969A (zh) * 2018-05-31 2020-06-16 南韓商Ｃ＆Ｃ新藥研究所 雜環衍生物及其用途
CN112707846B (zh) * 2019-10-25 2023-04-21 成都伊诺达博医药科技有限公司 一种达克替尼关键中间体的制备方法
CN114133395A (zh) * 2021-10-21 2022-03-04 中国科学院成都有机化学有限公司 具有荧光特性的吡咯并喹唑啉酮骨架化合物、制备方法、用途
CN114031619A (zh) * 2021-12-17 2022-02-11 山东汇海医药化工有限公司 一种图卡替尼中间体的制备方法
CN115433093A (zh) * 2022-09-26 2022-12-06 无锡双启科技有限公司 一种3-氯-4-三氟甲基苯胺的制备方法
WO2024069577A1 (en) * 2022-09-29 2024-04-04 Jw Pharmaceutical Corporation Novel crystalline form of 1-(8-bromopyrido[2,3-e][1,2,4]triazolo[4,3-a]pyrazin-4-yl)-n-methylazetidin-3-amine
WO2024069576A1 (en) * 2022-09-30 2024-04-04 Jw Pharmaceutical Corporation Novel crystalline form of 1-(8-bromopyrido[2,3-e][1,2,4]triazolo[4,3-a]pyrazin-4-yl)-n-methylazetidin-3-amine mono succinate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008003702A2 (en) * 2006-07-03 2008-01-10 Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg Fused bicyclic compounds interacting with the histamine h4 receptor
GB2454549B (en) * 2007-09-25 2009-09-23 Medical & Pharm Ind Tech & Dev Uses of 2-[piperidinyl]methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one for providing an anti-allergic effect and histamine H1 receptor antagonism effect

Also Published As

Publication number Publication date
WO2011112731A3 (en) 2012-01-12
WO2011112731A2 (en) 2011-09-15
US20110257137A1 (en) 2011-10-20
TW201204727A (en) 2012-02-01

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Effective date: 20191217